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Items: 1 to 20 of 88

1.
Junctional adhesion molecule-A: functional diversity through molecular promiscuity
Tim Steinbacher, Daniel Kummer, Klaus Ebnet
Cell Mol Life Sci. 2018 Apr; 75(8): 1393–1409. Published online 2017 Dec 14. doi: 10.1007/s00018-017-2729-0
PMCID:
PMC11105642
AbstractArticlePDF–2.0M
2.
Spike S1 domain interactome in non-pulmonary systems: A role beyond the receptor recognition
Ilaria Iacobucci, Vittoria Monaco, Luisa Canè, Francesca Bibbò, Valentina Cioffi, Flora Cozzolino, Alfredo Guarino, Massimo Zollo, Maria Monti
Front Mol Biosci. 2022; 9: 975570. Published online 2022 Sep 26. doi: 10.3389/fmolb.2022.975570
PMCID:
PMC9550266
AbstractArticlePDF–2.5M
3.
A Transcriptional Link between HER2, JAM-A and FOXA1 in Breast Cancer
Rodrigo G. B. Cruz, Stephen F. Madden, Kieran Brennan, Ann M. Hopkins
Cells. 2022 Feb; 11(4): 735. Published online 2022 Feb 19. doi: 10.3390/cells11040735
PMCID:
PMC8870165
AbstractArticlePDF–4.7M
4.
MIR21-induced loss of junctional adhesion molecule A promotes activation of oncogenic pathways, progression and metastasis in colorectal cancer
Andrea Lampis, Jens C. Hahne, Pierluigi Gasparini, Luciano Cascione, Somaieh Hedayat, Georgios Vlachogiannis, Claudio Murgia, Elisa Fontana, Joanne Edwards, Paul G. Horgan, Luigi Terracciano, Owen J. Sansom, Carlos D. Martins, Gabriela Kramer-Marek, Carlo M. Croce, Chiara Braconi, Matteo Fassan, Nicola Valeri
Cell Death Differ. 2021 Oct; 28(10): 2970–2982. Published online 2021 Jul 5. doi: 10.1038/s41418-021-00820-0
PMCID:
PMC8481293
AbstractArticlePDF–5.0M
5.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
6.
Helicobacter pylori PqqE is a new virulence factor that cleaves junctional adhesion molecule A and disrupts gastric epithelial integrity
Miguel S. Marques, Ana C. Costa, Hugo Osório, Marta L. Pinto, Sandra Relvas, Mário Dinis-Ribeiro, Fátima Carneiro, Marina Leite, Ceu Figueiredo
Gut Microbes. 2021; 13(1): 1921928. Published online 2021 May 10. doi: 10.1080/19490976.2021.1921928
PMCID:
PMC8115454
AbstractArticlePDF–3.5M
7.
Anti-CD321 antibody immunotherapy protects liver against ischemia and reperfusion-induced injury
Enzhi Yin, Takeshi Fukuhara, Kazuyoshi Takeda, Yuko Kojima, Kyoko Fukuhara, Kenichi Ikejima, Hisashi Bashuda, Jiro Kitaura, Hideo Yagita, Ko Okumura, Koichiro Uchida
Sci Rep. 2021; 11: 6312. Published online 2021 Mar 18. doi: 10.1038/s41598-021-85001-2
PMCID:
PMC7973783
AbstractArticlePDF–9.6M
8.
Aberrant expression of junctional adhesion molecule‐A contributes to the malignancy of cervical adenocarcinoma by interaction with poliovirus receptor/CD155
Taro Murakami, Akira Takasawa, Kumi Takasawa, Taishi Akimoto, Tomoyuki Aoyama, Kazufumi Magara, Yuki Saito, Misaki Ota, Daisuke Kyuno, Soh Yamamoto, Tadashi Hasegawa, Tsuyoshi Saito, Makoto Osanai
Cancer Sci. 2021 Feb; 112(2): 906–917. Published online 2020 Dec 5. doi: 10.1111/cas.14734
PMCID:
PMC7893988
AbstractArticlePDF–1.4M
9.
Junctional adhesion molecules in cancer: a paradigm for the diverse functions of cell-cell interactions in tumor progression
Adam Lauko, Zhaomei Mu, David H. Gutmann, Ulhas P. Naik, Justin D. Lathia
Cancer Res. Author manuscript; available in PMC 2021 May 15.
Published in final edited form as: Cancer Res. 2020 Nov 15; 80(22): 4878–4885. Published online 2020 Aug 14. doi: 10.1158/0008-5472.CAN-20-1829
PMCID:
PMC7669553
AbstractArticlePDF–674K
10.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
11.
Investigation of JAM-A (rs790056) and LFA-1 (rs8058823) gene variants in Turkish colorectal cancer patients
Burcu Çaykara, Hani Alsaadoni, Halime Hanım Pençe, Sadrettin Pençe, Hülya Yılmaz Aydoğan, Didem Taştekin
Turk J Gastroenterol. 2019 Oct; 30(10): 872–876. Published online 2019 Oct 1. doi: 10.5152/tjg.2019.19141
PMCID:
PMC6812956
AbstractArticlePDF–112K
12.
LZTR1 is a regulator of RAS ubiquitination and signaling
Johannes W. Bigenzahn, Giovanna M. Collu, Felix Kartnig, Melanie Pieraks, Gregory I. Vladimer, Leonhard X. Heinz, Vitaly Sedlyarov, Fiorella Schischlik, Astrid Fauster, Manuele Rebsamen, Katja Parapatics, Vincent A. Blomen, André C. Müller, Georg E. Winter, Robert Kralovics, Thijn R. Brummelkamp, Marek Mlodzik, Giulio Superti-Furga
Science. Author manuscript; available in PMC 2019 Oct 15.
Published in final edited form as: Science. 2018 Dec 7; 362(6419): 1171–1177. Published online 2018 Nov 15. doi: 10.1126/science.aap8210
PMCID:
PMC6794158
AbstractArticlePDF–1.9M
13.
Role of JAM-A tyrosine phosphorylation in epithelial barrier dysfunction during intestinal inflammation
Shuling Fan, Caroline M. Weight, Anny-Claude Luissint, Roland S. Hilgarth, Jennifer C. Brazil, Mark Ettel, Asma Nusrat, Charles A. Parkos
Mol Biol Cell. 2019 Mar 1; 30(5): 566–578. doi: 10.1091/mbc.E18-08-0531
PMCID:
PMC6589701
AbstractArticlePDF–2.1M
14.
The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2
Joanna R. Kovalski, Aparna Bhaduri, Ashley M. Zehnder, Poornima H. Neela, Yonglu Che, Glenn G. Wozniak, Paul A. Khavari
Mol Cell. Author manuscript; available in PMC 2020 Feb 21.
Published in final edited form as: Mol Cell. 2019 Feb 21; 73(4): 830–844.e12. Published online 2019 Jan 10. doi: 10.1016/j.molcel.2018.12.001
PMCID:
PMC6386588
AbstractArticlePDF–1.7M
15.
Blood-Brain Barrier: From Physiology to Disease and Back
Melanie D. Sweeney, Zhen Zhao, Axel Montagne, Amy R. Nelson, Berislav V. Zlokovic
Physiol Rev. 2019 Jan 1; 99(1): 21–78. Published online 2018 Oct 3. doi: 10.1152/physrev.00050.2017
PMCID:
PMC6335099
AbstractArticle
16.
Discovery of a Human Testis-specific Protein Complex TEX101-DPEP3 and Selection of Its Disrupting Antibodies
Christina Schiza, Dimitrios Korbakis, Efstratia Panteleli, Keith Jarvi, Andrei P. Drabovich, Eleftherios P. Diamandis
Mol Cell Proteomics. 2018 Dec; 17(12): 2480–2495. Published online 2018 Aug 10. doi: 10.1074/mcp.RA118.000749
PMCID:
PMC6283293
AbstractArticlePDF–1.9M
17.
Cleavage of the extracellular domain of junctional adhesion molecule-A is associated with resistance to anti-HER2 therapies in breast cancer settings
Astrid O. Leech, Sri HariKrishna Vellanki, Emily J. Rutherford, Aoife Keogh, Hanne Jahns, Lance Hudson, Norma O’Donovan, Siham Sabri, Bassam Abdulkarim, Katherine M. Sheehan, Elaine W. Kay, Leonie S. Young, Arnold D. K. Hill, Yvonne E. Smith, Ann M. Hopkins
Breast Cancer Res. 2018; 20: 140. Published online 2018 Nov 20. doi: 10.1186/s13058-018-1064-1
PMCID:
PMC6247757
AbstractArticlePDF–2.4M
18.
A membrane fusion protein, Ykt6, regulates epithelial cell migration via microRNA-mediated suppression of Junctional Adhesion Molecule A
Nayden G. Naydenov, Supriya Joshi, Alex Feygin, Siddharth Saini, Larisa Litovchick, Andrei I. Ivanov
Cell Cycle. 2018; 17(14): 1812–1831. Published online 2018 Aug 4. doi: 10.1080/15384101.2018.1496755
PMCID:
PMC6133332
AbstractArticlePDF–3.6M
19.
Interrogating the protein interactomes of RAS isoforms identifies PIP5K1A as a KRAS-specific vulnerability
Hema Adhikari, Christopher M. Counter
Nat Commun. 2018; 9: 3646. Published online 2018 Sep 7. doi: 10.1038/s41467-018-05692-6
PMCID:
PMC6128905
AbstractArticlePDF–2.2M
20.
JAM-A knockdown accelerates the proliferation and migration of human keratinocytes, and improves wound healing in rats via FAK/Erk signaling
Yunchuan Wang, Jianping Zheng, Yue Han, Yijie Zhang, Linlin Su, Dahai Hu, Xiaobing Fu
Cell Death Dis. 2018 Sep; 9(9): 848. Published online 2018 Aug 28. doi: 10.1038/s41419-018-0941-y
PMCID:
PMC6113279
AbstractArticlePDF–4.7M

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