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Items: 1 to 20 of 328

1.
Increased Protein Kinase A Activity Induces Fibrolamellar Hepatocellular Carcinoma Features Independent of DNAJB1
Mahsa Shirani, Solomon Levin, Bassem Shebl, David Requena, Tova M. Finkelstein, Daniel S. Johnson, Denise Ng, Gadi Lalazar, Søren Heissel, Peter Hojrup, Henrik Molina, Ype P. de Jong, Charles M. Rice, Aatur D. Singhi, Michael S. Torbenson, Philip Coffino, Barbara Lyons, Sanford M. Simon
Cancer Res. 2024 Aug 15; 84(16): 2626–2644. Published online 2024 Jun 18. doi: 10.1158/0008-5472.CAN-23-4110
PMCID:
PMC11325150
AbstractArticlePDF–15M
2.
DSBSO-Based XL-MS Analysis of Breast Cancer PDX Tissues to Delineate Protein Interaction Network in Clinical Samples
Fenglong Jiao, Clinton Yu, Andrew Wheat, Lijun Chen, Tung-Shing Mamie Lih, Hui Zhang, Lan Huang
J Proteome Res. Author manuscript; available in PMC 2024 Aug 3.
Published in final edited form as: J Proteome Res. 2024 Aug 2; 23(8): 3269–3279. Published online 2024 Feb 9. doi: 10.1021/acs.jproteome.3c00832
PMCID:
PMC11296914
AbstractArticlePDF–1.7M
3.
Antagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability
Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold, Christopher E. Pearson
Cell. Author manuscript; available in PMC 2024 Oct 26.
Published in final edited form as: Cell. 2023 Oct 26; 186(22): 4898–4919.e25. Published online 2023 Oct 11. doi: 10.1016/j.cell.2023.09.008
PMCID:
PMC11209935
AbstractArticlePDF–3.0M
4.
Current insights into the role of PKA phosphorylation in CFTR channel activity and the pharmacological rescue of cystic fibrosis disease-causing mutants
Stephanie Chin, Maurita Hung, Christine E. Bear
Cell Mol Life Sci. 2017 Jan; 74(1): 57–66. Published online 2016 Oct 8. doi: 10.1007/s00018-016-2388-6
PMCID:
PMC11107731
AbstractArticlePDF–793K
5.
Protein kinase A is a functional component of focal adhesions
Mingu Kang, Amanda J. Senatore, Hannah Naughton, Madeline McTigue, Rachel J. Beltman, Andrew A. Herppich, Mary Kay H. Pflum, Alan K. Howe
J Biol Chem. 2024 May; 300(5): 107234. Published online 2024 Mar 27. doi: 10.1016/j.jbc.2024.107234
PMCID:
PMC11044056
AbstractArticlePDF–3.5M
6.
The PKA-CREB1 axis regulates coronavirus proliferation by viral helicase nsp13 association
Tong Zheng, Beilei Shen, Yu Bai, Entao Li, Xun Zhang, Yong Hu, Ting Gao, Qincai Dong, Lin Zhu, Rui Jin, Hui Shi, Hainan Liu, Yuwei Gao, Xuan Liu, Cheng Cao
J Virol. 2024 Apr; 98(4): e01565-23. Published online 2024 Mar 6. doi: 10.1128/jvi.01565-23
PMCID:
PMC11019953
AbstractArticlePDF–2.3M
7.
In Vitro Reconstitution and Analysis of SARS-CoV-2/Host Protein–Protein Interactions
Shayli Varasteh Moradi, Yue Wu, Patricia Walden, Zhenling Cui, Wayne A. Johnston, Dmitri Petrov, Kirill Alexandrov
ACS Omega. 2023 Jul 18; 8(28): 25009–25019. Published online 2023 Jul 6. doi: 10.1021/acsomega.3c01625
PMCID:
PMC10357528
AbstractArticlePDF–4.1M
8.
HAPSTR1 localizes HUWE1 to the nucleus to limit stress signaling pathways
Julie K. Monda, Xuezhen Ge, Moritz Hunkeler, Katherine A. Donovan, Michelle W. Ma, Cyrus Y. Jin, Marilyn Leonard, Eric S. Fischer, Eric J. Bennett
Cell Rep. Author manuscript; available in PMC 2023 Jun 19.
Published in final edited form as: Cell Rep. 2023 May 30; 42(5): 112496. Published online 2023 May 9. doi: 10.1016/j.celrep.2023.112496
PMCID:
PMC10279472
AbstractArticlePDF–2.9M
9.
PKA mediates modality-specific modulation of the mechanically gated ion channel PIEZO2
Irina Schaefer, Clement Verkest, Lucas Vespermann, Thomas Mair, Hannah Voß, Nadja Zeitzschel, Stefan G. Lechner
J Biol Chem. 2023 Jun; 299(6): 104782. Published online 2023 May 4. doi: 10.1016/j.jbc.2023.104782
PMCID:
PMC10240422
AbstractArticlePDF–7.8M
10.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
11.
TRIM21 ameliorates hepatic glucose and lipid metabolic disorders in type 2 diabetes mellitus by ubiquitination of PEPCK1 and FASN
Kaini Zhang, Chen Yang, Xin Zhou, Jin Liang, Jianjin Guo, Min Li, Yi Zhang, Shulin Shao, Peng Sun, Kai Li, Jingjing Huang, Fang Chen, Xiubin Liang, Dongming Su
Cell Mol Life Sci. 2023 Jun; 80(6): 168. Published online 2023 May 30. doi: 10.1007/s00018-023-04820-w
PMCID:
PMC10229743
AbstractArticlePDF–2.9M
12.
Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell
Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low
Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120
PMCID:
PMC10151615
AbstractArticlePDF–2.9M
13.
A screen for MeCP2-TBL1 interaction inhibitors using a luminescence-based assay
Beatrice Alexander-Howden, Li Zhang, Almer M. van der Sloot, Sylvain Tollis, Daniel J. St-Cyr, Frank Sicheri, Adrian P. Bird, Mike Tyers, Matthew J. Lyst
Sci Rep. 2023; 13: 3868. Published online 2023 Mar 8. doi: 10.1038/s41598-023-29915-z
PMCID:
PMC9995496
AbstractArticlePDF–2.4M
14.
The SpACE-CCM: A facile and versatile cell culture medium-based biosensor for detection of SARS-CoV-2 spike-ACE2 interaction
Youngwook Ham, Nam-Chul Cho, Daeyong Kim, Jung-Hee Kim, Min Ju Jo, Min Seon Jeong, Bo-Yeong Pak, Sanghyeok Lee, Mi-Kyung Lee, Seung-Wook Chi, Tae-Don Kim, Nak Cheol Jeong, Sungchan Cho
Biosens Bioelectron. 2023 May 1; 227: 115169. Published online 2023 Feb 19. doi: 10.1016/j.bios.2023.115169
PMCID:
PMC9938795
AbstractArticlePDF–6.0M
15.
Flotillin-2 regulates epidermal growth factor receptor activation, degradation by Cbl-mediated ubiquitination, and cancer growth
David J. Wisniewski, Mariya S. Liyasova, Soumya Korrapati, Xu Zhang, Shashikala Ratnayake, Qingrong Chen, Samuel F. Gilbert, Alexis Catalano, Donna Voeller, Daoud Meerzaman, Udayan Guha, Natalie Porat-Shliom, Christina M. Annunziata, Stanley Lipkowitz
J Biol Chem. 2023 Jan; 299(1): 102766. Published online 2022 Dec 5. doi: 10.1016/j.jbc.2022.102766
PMCID:
PMC9823131
AbstractArticlePDF–2.5M
16.
A whole genome CRISPR screen identifies AHR loss as a mechanism of resistance to a PARP7 inhibitor
Huadong Chen, Morgan E. Diolaiti, Patrick C. O’Leary, Ajda Rojc, Nevan J. Krogan, Minkyu Kim, Alan Ashworth
Mol Cancer Ther. Author manuscript; available in PMC 2023 Jan 5.
Published in final edited form as: Mol Cancer Ther. 2022 Jul 5; 21(7): 1076–1089. doi: 10.1158/1535-7163.MCT-21-0841
PMCID:
PMC9769698
AbstractArticlePDF–2.7M
17.
Defective synaptic plasticity in a model of Coffin–Lowry syndrome is rescued by simultaneously targeting PKA and MAPK pathways
Rong-Yu Liu, Yili Zhang, Paul Smolen, Leonard J. Cleary, John H. Byrne
Learn Mem. 2022 Dec; 29(12): 435–446. Published online 2022 Dec. doi: 10.1101/lm.053625.122
PMCID:
PMC9749851
AbstractArticlePDF–3.8M
18.
SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis
Jun-yi Zhu, Guanglei Wang, Xiaohu Huang, Hangnoh Lee, Jin-Gu Lee, Penghua Yang, Joyce van de Leemput, Weiliang Huang, Maureen A. Kane, Peixin Yang, Zhe Han
Commun Biol. 2022; 5: 1039. Published online 2022 Sep 30. doi: 10.1038/s42003-022-03986-6
PMCID:
PMC9523645
AbstractArticlePDF–3.9M
19.
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery
Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili
Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z
PMCID:
PMC9279285
AbstractArticlePDF–2.5M
20.
Physical and functional interactome atlas of human receptor tyrosine kinases
Kari Salokas, Xiaonan Liu, Tiina Öhman, Iftekhar Chowdhury, Lisa Gawriyski, Salla Keskitalo, Markku Varjosalo
EMBO Rep. 2022 Jun; 23(6): e54041. Published online 2022 Apr 5. doi: 10.15252/embr.202154041
PMCID:
PMC9171411
AbstractArticlePDF–1.9M

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