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Select item 74329121.

Alterations of STEP46 and STEP61 Expression in the Rat Retina with Age and AMD-Like Retinopathy Development

Darya V. Telegina, Elizabeth A. Kulikova, Oyuna S. Kozhevnikova, Alexander V. Kulikov, Tatyana M. Khomenko, Konstantin P. Volcho, Nariman F. Salakhutdinov, Nataliya G. Kolosova

Int J Mol Sci. 2020 Aug; 21(15): 5182. Published online 2020 Jul 22. doi: 10.3390/ijms21155182

PMCID:: PMC7432912

Abstract Article PDF–1.6M

Select item 67257342.

Fyn Kinase Induces Synaptic and Cognitive Impairments in a Transgenic Mouse Model of Alzheimer's Disease

Jeannie Chin, Jorge J. Palop, Jukka Puoliväli, Catherine Massaro, Nga Bien-Ly, Hilary Gerstein, Kimberly Scearce-Levie, Eliezer Masliah, Lennart Mucke

J Neurosci. 2005 Oct 19; 25(42): 9694–9703. doi: 10.1523/JNEUROSCI.2980-05.2005

PMCID:: PMC6725734

Abstract Article PDF–802K

Select item 65792373.

STEP₆₁: A Member of a Family of Brain-Enriched PTPs Is Localized to the Endoplasmic Reticulum

Abel Bult, Feisha Zhao, Ronald Dirkx Jr., Ela Sharma, Erika Lukacsi, Michele Solimena, Janice R. Naegele, Paul J. Lombroso

J Neurosci. 1996 Dec 15; 16(24): 7821–7831. doi: 10.1523/JNEUROSCI.16-24-07821.1996

PMCID:: PMC6579237

Abstract Article PDF–1.2M

Select item 65778444.

Cellular and molecular characterization of a brain-enriched protein tyrosine phosphatase

LM Boulanger, PJ Lombroso, A Raghunathan, MJ During, P Wahle, JR Naegele

J Neurosci. 1995 Feb 1; 15(2): 1532–1544. doi: 10.1523/JNEUROSCI.15-02-01532.1995

PMCID:: PMC6577844

Abstract PDF–3.0M

Select item 65766875.

A protein tyrosine phosphatase expressed within dopaminoceptive neurons of the basal ganglia and related structures

PJ Lombroso, JR Naegele, E Sharma, M Lerner

J Neurosci. 1993 Jul 1; 13(7): 3064–3074. doi: 10.1523/JNEUROSCI.13-07-03064.1993

PMCID:: PMC6576687

Abstract PDF–4.8M

Select item 56682056.

Synaptic NMDA receptor activation induces ubiquitination and degradation of STEP₆₁

Jian Xu, Pradeep Kurup, Angus C. Nairn, Paul J. Lombroso

Mol Neurobiol. Author manuscript; available in PMC 2019 Apr 1.

Published in final edited form as: Mol Neurobiol. 2018 Apr; 55(4): 3096–3111. Published online 2017 May 2. doi: 10.1007/s12035-017-0555-x

PMCID:: PMC5668205

Abstract Article PDF–2.8M

Select item 51145537.

STEP activation by Gαq coupled GPCRs opposes Src regulation of NMDA receptors containing the GluN2A subunit

Meng Tian, Jian Xu, Gang Lei, Paul J. Lombroso, Michael F. Jackson, John F. MacDonald

Sci Rep. 2016; 6: 36684. Published online 2016 Nov 18. doi: 10.1038/srep36684

PMCID:: PMC5114553

Abstract Article PDF–2.3M

Select item 49877928.

PSD-95 stabilizes NMDA receptors by inducing the degradation of STEP₆₁

Sehoon Won, Salvatore Incontro, Roger A. Nicoll, Katherine W. Roche

Proc Natl Acad Sci U S A. 2016 Aug 9; 113(32): E4736–E4744. Published online 2016 Jul 25. doi: 10.1073/pnas.1609702113

PMCID:: PMC4987792

Abstract Article PDF–1.5M

Select item 48419199.

Aging is associated with dimerization and inactivation of the brain-enriched tyrosine phosphatase STEP

Sathyanarayanan Rajagopal, Ishani Deb, Ranjana Poddar, Surojit Paul

Neurobiol Aging. Author manuscript; available in PMC 2017 May 1.

Published in final edited form as: Neurobiol Aging. 2016 May; 41: 25–38. Published online 2016 Feb 12. doi: 10.1016/j.neurobiolaging.2016.02.004

PMCID:: PMC4841919

Abstract Article PDF–1.8M

Select item 470540010.

Zn²⁺-dependent Activation of the Trk Signaling Pathway Induces Phosphorylation of the Brain-enriched Tyrosine Phosphatase STEP: MOLECULAR BASIS FOR ZN²⁺-INDUCED ERK MAPK ACTIVATION

Ranjana Poddar, Sathyanarayanan Rajagopal, C. William Shuttleworth, Surojit Paul

J Biol Chem. 2016 Jan 8; 291(2): 813–825. Published online 2015 Nov 16. doi: 10.1074/jbc.M115.663468

PMCID:: PMC4705400

Abstract Article PDF–2.0M

Select item 457824211.

Regulation of STEP₆₁ and tyrosine-phosphorylation of NMDA and AMPA receptors during homeostatic synaptic plasticity

Sung-Soo Jang, Sara E. Royston, Jian Xu, John P. Cavaretta, Max O. Vest, Kwan Young Lee, Seungbae Lee, Han Gil Jeong, Paul J. Lombroso, Hee Jung Chung

Mol Brain. 2015; 8: 55. Published online 2015 Sep 22. doi: 10.1186/s13041-015-0148-4

PMCID:: PMC4578242

Abstract Article PDF–1.9M

Select item 451662812.

STriatal-Enriched protein tyrosine Phosphatase (STEP) Regulates the PTPα/Fyn Signaling Pathway

Jian Xu, Pradeep Kurup, Ethan Foscue, Paul J. Lombroso

J Neurochem. Author manuscript; available in PMC 2016 Aug 1.

Published in final edited form as: J Neurochem. 2015 Aug; 134(4): 629–641. Published online 2015 May 25. doi: 10.1111/jnc.13160

PMCID:: PMC4516628

Abstract Article PDF–1.2M

Select item 431384613.

STEP₆₁ is a substrate of the E3 ligase parkin and is upregulated in Parkinson’s disease

Pradeep K. Kurup, Jian Xu, Rita Alexandra Videira, Chimezie Ononenyi, Graça Baltazar, Paul J. Lombroso, Angus C. Nairn

Proc Natl Acad Sci U S A. 2015 Jan 27; 112(4): 1202–1207. Published online 2015 Jan 12. doi: 10.1073/pnas.1417423112

PMCID:: PMC4313846

Abstract Article PDF–1.1M

Select item 381855414.

Neuroprotective Role of a Brain-Enriched Tyrosine Phosphatase, STEP, in Focal Cerebral Ischemia

Ishani Deb, Namratta Manhas, Ranjana Poddar, Sathyanarayanan Rajagopal, Andrea M. Allan, Paul J. Lombroso, Gary A. Rosenberg, Eduardo Candelario-Jalil, Surojit Paul

J Neurosci. 2013 Nov 6; 33(45): 17814–17826. doi: 10.1523/JNEUROSCI.2346-12.2013

PMCID:: PMC3818554

Abstract Article PDF–3.0M

Select item 339098615.

In Vitro Stretch Injury Induces Time- and Severity-Dependent Alterations of STEP Phosphorylation and Proteolysis in Neurons

Mahlet N. Mesfin, Catherine R. von Reyn, Rosalind E. Mott, Mary E. Putt, David F. Meaney

J Neurotrauma. 2012 Jul 1; 29(10): 1982–1998. doi: 10.1089/neu.2011.2253

PMCID:: PMC3390986

Abstract Article PDF–917K

Select item 317805916.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 303542117.

NR2B-NMDA receptor mediated modulation of the tyrosine phosphatase STEP regulates glutamate induced neuronal cell death

Ranjana Poddar, Ishani Deb, Saibal Mukherjee, Surojit Paul

J Neurochem. Author manuscript; available in PMC 2011 Dec 1.

Published in final edited form as: J Neurochem. 2010 Dec; 115(6): 1350–1362. Published online 2010 Nov 2. doi: 10.1111/j.1471-4159.2010.07035.x

PMCID:: PMC3035421

Abstract Article PDF–2.1M

Select item 297389218.

Genetic reduction of striatal-enriched tyrosine phosphatase (STEP) reverses cognitive and cellular deficits in an Alzheimer’s disease mouse model

Yongfang Zhang, Pradeep Kurup, Jian Xu, Nikisha Carty, Stephanie M. Fernandez, Haakon B. Nygaard, Christopher Pittenger, Paul Greengard, Stephen M. Strittmatter, Angus C. Nairn, Paul J. Lombroso

Proc Natl Acad Sci U S A. 2010 Nov 2; 107(44): 19014–19019. Published online 2010 Oct 18. doi: 10.1073/pnas.1013543107