PMC Links for GEO Profiles (Select 109669649) - PMC

Result Filters

Links from GEO Profiles

Items: 17

Select item 66817571.

Site-specific phosphorylation of myosin binding protein-C coordinates thin and thick filament activation in cardiac muscle

Saraswathi Ponnam, Ivanka Sevrieva, Yin-Biao Sun, Malcolm Irving, Thomas Kampourakis

Proc Natl Acad Sci U S A. 2019 Jul 30; 116(31): 15485–15494. Published online 2019 Jul 15. doi: 10.1073/pnas.1903033116

PMCID:: PMC6681757

Abstract Article PDF–1.6M

Select item 61395722.

Structural and functional effects of myosin-binding protein-C phosphorylation in heart muscle are not mimicked by serine-to-aspartate substitutions

Thomas Kampourakis, Saraswathi Ponnam, Yin-Biao Sun, Ivanka Sevrieva, Malcolm Irving

J Biol Chem. 2018 Sep 14; 293(37): 14270–14275. Published online 2018 Aug 6. doi: 10.1074/jbc.AC118.004816

PMCID:: PMC6139572

Abstract Article PDF–798K

Select item 50052823.

A post-MI power struggle: adaptations in cardiac power occur at the sarcomere level alongside MyBP-C and RLC phosphorylation

Christopher N. Toepfer, Markus B. Sikkel, Valentina Caorsi, Anupama Vydyanath, Iratxe Torre, O'Neal Copeland, Alexander R. Lyon, Steven B. Marston, Pradeep K. Luther, Kenneth T. Macleod, Timothy G. West, Michael A. Ferenczi

Am J Physiol Heart Circ Physiol. 2016 Aug 1; 311(2): H465–H475. Published online 2016 May 27. doi: 10.1152/ajpheart.00899.2015

PMCID:: PMC5005282

Abstract Article

Select item 46380454.

Interacting Network of the Gap Junction (GJ) Protein Connexin43 (Cx43) is Modulated by Ischemia and Reperfusion in the Heart

Tania Martins-Marques, Sandra Isabel Anjo, Paulo Pereira, Bruno Manadas, Henrique Girão

Mol Cell Proteomics. 2015 Nov; 14(11): 3040–3055. Published online 2015 Aug 27. doi: 10.1074/mcp.M115.052894

PMCID:: PMC4638045

Abstract Article PDF–2.5M

Select item 44054915.

A Novel Phosphorylation Site, Serine 199, in the C-Terminus of Cardiac Troponin I Regulates Calcium Sensitivity and Susceptibility to Calpain-Induced Proteolysis

Paul J.M. Wijnker, Yuejin Li, Pingbo Zhang, D. Brian Foster, Cris dos Remedios, Jennifer E. Van Eyk, Ger J.M. Stienen, Anne M. Murphy, Jolanda van der Velden

J Mol Cell Cardiol. Author manuscript; available in PMC 2016 May 1.

Published in final edited form as: J Mol Cell Cardiol. 2015 May; 82: 93–103. Published online 2015 Mar 11. doi: 10.1016/j.yjmcc.2015.03.006

PMCID:: PMC4405491

Abstract Article PDF–1.3M

Select item 43424936.

A Hypertrophic Cardiomyopathy-associated MYBPC3 Mutation Common in Populations of South Asian Descent Causes Contractile Dysfunction

Diederik W. D. Kuster, Suresh Govindan, Tzvia I. Springer, Jody L. Martin, Natosha L. Finley, Sakthivel Sadayappan

J Biol Chem. 2015 Feb 27; 290(9): 5855–5867. Published online 2015 Jan 12. doi: 10.1074/jbc.M114.607911

PMCID:: PMC4342493

Abstract Article PDF–2.8M

Select item 42845307.

Myosin binding protein-C activates thin filaments and inhibits thick filaments in heart muscle cells

Thomas Kampourakis, Ziqian Yan, Mathias Gautel, Yin-Biao Sun, Malcolm Irving

Proc Natl Acad Sci U S A. 2014 Dec 30; 111(52): 18763–18768. Published online 2014 Dec 15. doi: 10.1073/pnas.1413922112

PMCID:: PMC4284530

Abstract Article PDF–1.0M

Select item 40233168.

Atrogin-1 and MuRF1 regulate cardiac MyBP-C levels via different mechanisms

Giulia Mearini, Christina Gedicke, Saskia Schlossarek, Christian C. Witt, Elisabeth Krämer, Peirang Cao, Marcelo D. Gomes, Stewart H. Lecker, Siegfried Labeit, Monte S. Willis, Thomas Eschenhagen, Lucie Carrier

Cardiovasc Res. 2010 Jan 15; 85(2): 357–366. Published online 2009 Oct 22. doi: 10.1093/cvr/cvp348

PMCID:: PMC4023316

Abstract Article PDF–522K

Select item 34960579.

Determination of the critical residues responsible for cardiac myosin binding protein C’s interactions

Md. Shenuarin Bhuiyan, James Gulick, Hanna Osinska, Manish Gupta, Jeffrey Robbins

J Mol Cell Cardiol. Author manuscript; available in PMC 2013 Dec 1.

Published in final edited form as: J Mol Cell Cardiol. 2012 Dec; 53(6): 838–847. Published online 2012 Sep 11. doi: 10.1016/j.yjmcc.2012.08.028

PMCID:: PMC3496057

Abstract Article PDF–2.5M

Select item 336827710.

Pathogenic properties of the N-terminal region of cardiac myosin binding protein-C in vitro

Suresh Govindan, Jason Sarkey, Xiang Ji, Nagalingam R. Sundaresan, Mahesh P. Gupta, Pieter P. de Tombe, Sakthivel Sadayappan

J Muscle Res Cell Motil. Author manuscript; available in PMC 2013 May 1.

Published in final edited form as: J Muscle Res Cell Motil. 2012 May; 33(1): 17–30. Published online 2012 Apr 17. doi: 10.1007/s10974-012-9292-y

PMCID:: PMC3368277

Abstract Article PDF–2.9M

Select item 324611811.

Cardiac myosin binding protein-C is a potential diagnostic biomarker for myocardial infarction

Suresh Govindan, Andrew McElligott, Saminathan Muthusamy, Nandini Nair, David Barefield, Jody L. Martin, Enrique Gongora, Kenneth D. Greis, Pradeep K. Luther, Saul Winegrad, Kyle K. Henderson, Sakthivel Sadayappan

J Mol Cell Cardiol. Author manuscript; available in PMC 2013 Jan 1.

Published in final edited form as: J Mol Cell Cardiol. 2012 Jan; 52(1): 154–164. Published online 2011 Sep 19. doi: 10.1016/j.yjmcc.2011.09.011

PMCID:: PMC3246118

Abstract Article PDF–4.0M

Select item 317805912.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 189227713.

Radial displacement of myosin cross-bridges in mouse myocardium due to ablation of myosin binding protein-C

Brett A. Colson, Tanya Bekyarova, Daniel P. Fitzsimons, Thomas C. Irving, Richard L. Moss

J Mol Biol. Author manuscript; available in PMC 2008 Mar 16.

Published in final edited form as: J Mol Biol. 2007 Mar 16; 367(1): 36–41. Published online 2006 Dec 28. doi: 10.1016/j.jmb.2006.12.063

PMCID:: PMC1892277

Abstract Article PDF–719K

Select item 163655414.

Cardiac myosin binding protein c phosphorylation is cardioprotective

Sakthivel Sadayappan, Hanna Osinska, Raisa Klevitsky, John N. Lorenz, Michelle Sargent, Jeffrey D. Molkentin, Christine E. Seidman, Jonathan G. Seidman, Jeffrey Robbins

Proc Natl Acad Sci U S A. 2006 Nov 7; 103(45): 16918–16923. Published online 2006 Oct 30. doi: 10.1073/pnas.0607069103

PMCID:: PMC1636554

Abstract Article PDF–577K

Select item 134349415.

Cardiac Myosin Binding Protein-C Phosphorylation and Cardiac Function

Sakthivel Sadayappan, James Gulick, Hanna Osinska, Lisa A. Martin, Harvey S. Hahn, Gerald W. Dorn, II, Raisa Klevitsky, Christine E. Seidman, Jonathan G. Seidman, Jeffrey Robbins.

Circ Res. Author manuscript; available in PMC 2006 May 25.

Published in final edited form as: Circ Res. 2005 Nov 25; 97(11): 1156–1163. Published online 2005 Oct 13. doi: 10.1161/01.RES.0000190605.79013.4d

PMCID:: PMC1343494

Abstract Article PDF–1.8M

Select item 40981916.

Dilated cardiomyopathy in homozygous myosin-binding protein-C mutant mice

Bradley K. McConnell, Karen A. Jones, Diane Fatkin, Luis H. Arroyo, Richard T. Lee, Orlando Aristizabal, Daniel H. Turnbull, Dimitrios Georgakopoulos, David Kass, Meredith Bond, Hideshi Niimura, Frederick J. Schoen, David Conner, Donald H. Fischman, Christine E. Seidman, J.G. Seidman

J Clin Invest. 1999 Nov 1; 104(9): 1235–1244. doi: 10.1172/JCI7377