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Items: 1 to 20 of 46

1.
Ubiquitylation of nucleic acids by DELTEX ubiquitin E3 ligase DTX3L
Kang Zhu, Chatrin Chatrin, Marcin J Suskiewicz, Vincent Aucagne, Benjamin Foster, Benedikt M Kessler, Ian Gibbs-Seymour, Dragana Ahel, Ivan Ahel
EMBO Rep. 2024 Oct; 25(10): 4172–4189. Published online 2024 Sep 6. doi: 10.1038/s44319-024-00235-1
PMCID:
PMC11467253
AbstractArticlePDF–8.5M
2.
PARP14 is regulated by the PARP9/DTX3L complex and promotes interferon γ-induced ADP-ribosylation
Victoria Chaves Ribeiro, Lilian Cristina Russo, Nícolas Carlos Hoch
EMBO J. 2024 Jul; 43(14): 2908–2928. Published online 2024 Jun 4. doi: 10.1038/s44318-024-00125-1
PMCID:
PMC11251048
AbstractArticlePDF–3.6M
3.
DELTEX E3 ligases ubiquitylate ADP-ribosyl modification on nucleic acids
Kang Zhu, Marcin J Suskiewicz, Chatrin Chatrin, Øyvind Strømland, Bryan W Dorsey, Vincent Aucagne, Dragana Ahel, Ivan Ahel
Nucleic Acids Res. 2024 Jan 25; 52(2): 801–815. Published online 2023 Nov 24. doi: 10.1093/nar/gkad1119
PMCID:
PMC10810221
AbstractArticlePDF–1.6M
4.
Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates
Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert
Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644
PMCID:
PMC10565876
AbstractArticlePDF–3.7M
5.
DTX3L Enhances Type I Interferon Antiviral Response by Promoting the Ubiquitination and Phosphorylation of TBK1
Jiaqi Huang, Zhengrong Chen, Yunfei Ye, Yu Shao, Peijie Zhu, Xiaoping Li, Yu Ma, Fei Xu, Ji Zhou, Mengyun Wu, Xiu Gao, Yi Yang, Jinping Zhang, Chuangli Hao
J Virol. 2023 Jun; 97(6): e00687-23. Published online 2023 May 31. doi: 10.1128/jvi.00687-23
PMCID:
PMC10308958
AbstractArticlePDF–4.8M
6.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
7.
Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell
Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low
Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120
PMCID:
PMC10151615
AbstractArticlePDF–2.9M
8.
The p97/VCP segregase is essential for arsenic-induced degradation of PML and PML-RARA
Ellis G. Jaffray, Michael H. Tatham, Barbara Mojsa, Magda Liczmanska, Alejandro Rojas-Fernandez, Yili Yin, Graeme Ball, Ronald T. Hay
J Cell Biol. 2023 Apr 3; 222(4): e202201027. Published online 2023 Feb 28. doi: 10.1083/jcb.202201027
PMCID:
PMC10005898
AbstractArticlePDF–6.7M
9.
PARP7 mono-ADP-ribosylates the Agonist Conformation of the Androgen Receptor in the Nucleus
Teddy Kamata, Chun-Song Yang, Bryce M. Paschal
Biochem J. Author manuscript; available in PMC 2022 Sep 18.
Published in final edited form as: Biochem J. 2021 Aug 13; 478(15): 2999–3014. doi: 10.1042/BCJ20210378
PMCID:
PMC9482820
AbstractArticlePDF–1.4M
10.
ALS-linked loss of Cyclin-F function affects HSP90
Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends
Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359
PMCID:
PMC9481933
AbstractArticlePDF–3.5M
11.
Cullin 3 Exon 9 Deletion in Familial Hyperkalemic Hypertension Impairs Cullin3-Ring-E3 Ligase (CRL3) Dynamic Regulation and Cycling
Ilektra Kouranti, Waed Abdel Khalek, Stephani Mazurkiewicz, Irmine Loisel-Ferreira, Alexis M. Gautreau, Lionel Pintard, Xavier Jeunemaitre, Eric Clauser
Int J Mol Sci. 2022 May; 23(9): 5151. Published online 2022 May 5. doi: 10.3390/ijms23095151
PMCID:
PMC9105235
AbstractArticlePDF–5.8M
12.
Endofin is required for HD-PTP and ESCRT-0 interdependent endosomal sorting of ubiquitinated transmembrane cargoes
Jalal M. Kazan, Guillaume Desrochers, Claire E. Martin, Hyeonju Jeong, Dmitri Kharitidi, Pirjo M. Apaja, Ariel Roldan, Nicole St. Denis, Anne-Claude Gingras, Gergely L. Lukacs, Arnim Pause
iScience. 2021 Nov 19; 24(11): 103274. Published online 2021 Oct 14. doi: 10.1016/j.isci.2021.103274
PMCID:
PMC8567383
AbstractArticlePDF–5.3M
13.
The SARS-CoV-2 Nsp3 macrodomain reverses PARP9/DTX3L-dependent ADP-ribosylation induced by interferon signaling
Lilian Cristina Russo, Rebeka Tomasin, Isaac Araújo Matos, Antonio Carlos Manucci, Sven T. Sowa, Katie Dale, Keith W. Caldecott, Lari Lehtiö, Deborah Schechtman, Flavia C. Meotti, Alexandre Bruni-Cardoso, Nicolas Carlos Hoch
J Biol Chem. 2021 Sep; 297(3): 101041. Published online 2021 Aug 4. doi: 10.1016/j.jbc.2021.101041
PMCID:
PMC8332738
AbstractArticlePDF–3.4M
14.
TEM8 marks neovasculogenic tumor-initiating cells in triple-negative breast cancer
Jiahui Xu, Xiaoli Yang, Qiaodan Deng, Cong Yang, Dong Wang, Guojuan Jiang, Xiaohong Yao, Xueyan He, Jiajun Ding, Jiankun Qiang, Juchuanli Tu, Rui zhang, Qun-Ying Lei, Zhi-min Shao, Xiuwu Bian, Ronggui Hu, Lixing Zhang, Suling Liu
Nat Commun. 2021; 12: 4413. Published online 2021 Jul 20. doi: 10.1038/s41467-021-24703-7
PMCID:
PMC8292527
AbstractArticlePDF–6.5M
15.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
16.
DELTEX E3 ligases ubiquitylate ADP-ribosyl modification on protein substrates
Kang Zhu, Marcin J. Suskiewicz, Andrea Hloušek-Kasun, Hervé Meudal, Andreja Mikoč, Vincent Aucagne, Dragana Ahel, Ivan Ahel
Sci Adv. 2022 Oct; 8(40): eadd4253. Published online 2022 Oct 5. doi: 10.1126/sciadv.add4253
PMCID:
PMC7615817
AbstractArticlePDF–8.2M
17.
PDLIM5 inhibits STUB1-mediated degradation of SMAD3 and promotes the migration and invasion of lung cancer cells
Yueli Shi, Xinyu Wang, Zhiyong Xu, Ying He, Chunyi Guo, Lingjuan He, Caijuan Huan, Changhong Cai, Jiaqi Huang, Jie Zhang, Yiqing Li, Chunlai Zeng, Xue Zhang, Linrun Wang, Yuehai Ke, Hongqiang Cheng
J Biol Chem. 2020 Oct 2; 295(40): 13798–13811. Published online 2020 Jul 31. doi: 10.1074/jbc.RA120.014976
PMCID:
PMC7535919
AbstractArticlePDF–6.4M
18.
Structural insights into ADP-ribosylation of ubiquitin by Deltex family E3 ubiquitin ligases
Chatrin Chatrin, Mads Gabrielsen, Lori Buetow, Mark A. Nakasone, Syed F. Ahmed, David Sumpton, Gary J. Sibbet, Brian O. Smith, Danny T. Huang
Sci Adv. 2020 Sep; 6(38): eabc0418. Published online 2020 Sep 18. doi: 10.1126/sciadv.abc0418
PMCID:
PMC7500938
AbstractArticlePDF–3.4M
19.
DELTEX2 C-terminal domain recognizes and recruits ADP-ribosylated proteins for ubiquitination
Syed Feroj Ahmed, Lori Buetow, Mads Gabrielsen, Sergio Lilla, Chatrin Chatrin, Gary J. Sibbet, Sara Zanivan, Danny T. Huang
Sci Adv. 2020 Aug; 6(34): eabc0629. Published online 2020 Aug 21. doi: 10.1126/sciadv.abc0629
PMCID:
PMC7442474
AbstractArticlePDF–2.4M
20.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M

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