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Select item 112982031.

Deciphering the neuroprotective mechanisms of RACK1 in cerebral ischemia‐reperfusion injury: Pioneering insights into mitochondrial autophagy and the PINK1/Parkin axis

Lanqing Zhao, Yu Chen, Hongxi Li, Xiaoxu Ding, Jinwei Li

CNS Neurosci Ther. 2024 Aug; 30(8): e14836. Published online 2024 Aug 4. doi: 10.1111/cns.14836

PMCID:: PMC11298203

Abstract Article PDF–18M

Select item 109107372.

Prodromal Parkinson disease signs are predicted by a whole-blood inflammatory transcriptional signature in young Pink1^−/− rats

Sarah A. Lechner, David G. S. Barnett, Stephen C. Gammie, Cynthia A. Kelm-Nelson

BMC Neurosci. 2024; 25: 11. Published online 2024 Mar 4. doi: 10.1186/s12868-024-00857-0

PMCID:: PMC10910737

Abstract Article PDF–1.2M

Select item 105142383.

Pink1−/− rats demonstrate swallowing and gastrointestinal dysfunction in a model of prodromal Parkinson disease

Maryann N. Krasko, John Szot, Karolina Lungova, Linda M. Rowe, Glen Leverson, Cynthia A. Kelm-Nelson, Michelle R. Ciucci

Dysphagia. Author manuscript; available in PMC 2024 Apr 1.

Published in final edited form as: Dysphagia. 2023 Oct; 38(5): 1382–1397. Published online 2023 Mar 22. doi: 10.1007/s00455-023-10567-0

PMCID:: PMC10514238

Abstract Article PDF–1.7M

Select item 102363034.

Outlook of PINK1/Parkin signaling in molecular etiology of Parkinson’s disease, with insights into Pink1 knockout models

Zhangting Wang, See-Wing Chan, Hui Zhao, Kai-Kei Miu, Wai-Yee Chan

Zool Res. 2023 May 18; 44(3): 559–576. doi: 10.24272/j.issn.2095-8137.2022.406

PMCID:: PMC10236303

Abstract Article PDF–2.6M

Select item 97511155.

RhoA signaling increases mitophagy and protects cardiomyocytes against ischemia by stabilizing PINK1 protein and recruiting Parkin to mitochondria

Michelle Tu, Valerie P. Tan, Justin D. Yu, Raghav Tripathi, Zahna Bigham, Melissa Barlow, Jeffrey M. Smith, Joan Heller Brown, Shigeki Miyamoto

Cell Death Differ. 2022 Dec; 29(12): 2472–2486. Published online 2022 Jun 27. doi: 10.1038/s41418-022-01032-w

PMCID:: PMC9751115

Abstract Article PDF–6.5M

Select item 97415056.

SIAH proteins regulate the degradation and intra‐mitochondrial aggregation of PINK1: Implications for mitochondrial pathology in Parkinson's disease

Fatimah Abd Elghani, Hazem Safory, Haya Hamza, Mor Savyon, Malik Farhoud, Michal Toren‐Hershoviz, Zagorka Vitic, Kirsten Ebanks, Vered Shani, Sleman Bisharat, Lihi Shaulov, Claude Brodski, Zhiyin Song, Rina Bandopadhyay, Simone Engelender

Aging Cell. 2022 Dec; 21(12): e13731. Published online 2022 Oct 28. doi: 10.1111/acel.13731

PMCID:: PMC9741505

Abstract Article PDF–5.1M

Select item 95701617.

PINK1 Phosphorylates Drp1^S616 to Improve Mitochondrial Fission and Inhibit the Progression of Hypertension-Induced HFpEF

Jian Shou, Yunlong Huo

Int J Mol Sci. 2022 Oct; 23(19): 11934. Published online 2022 Oct 8. doi: 10.3390/ijms231911934

PMCID:: PMC9570161

Abstract Article PDF–7.9M

Select item 93460448.

The mitochondria-targeted antioxidant MitoQ ameliorates myocardial ischemia–reperfusion injury by enhancing PINK1/Parkin-mediated mitophagy in type 2 diabetic rats

Yelong Ji, Yan Leng, Shaoqing Lei, Zhen Qiu, Hao Ming, Yi Zhang, Aining Zhang, Yang Wu, Zhongyaun Xia

Cell Stress Chaperones. 2022 Jul; 27(4): 353–367. Published online 2022 Apr 15. doi: 10.1007/s12192-022-01273-1

PMCID:: PMC9346044

Abstract Article PDF–1.7M

Select item 93434609.

PINK1 overexpression prevents forskolin-induced tau hyperphosphorylation and oxidative stress in a rat model of Alzheimer’s disease

Xiao-juan Wang, Lin Qi, Ya-fang Cheng, Xue-fei Ji, Tian-yan Chi, Peng Liu, Li-bo Zou

Acta Pharmacol Sin. 2022 Aug; 43(8): 1916–1927. Published online 2021 Dec 10. doi: 10.1038/s41401-021-00810-5

PMCID:: PMC9343460

Abstract Article PDF–5.5M

Select item 814238810.

Changes to Ventilation, Vocalization, and Thermal Nociception in the Pink1−/− Rat Model of Parkinson’s Disease

Rebecca A. Johnson, Cynthia A. Kelm-Nelson, Michelle R. Ciucci

J Parkinsons Dis. Author manuscript; available in PMC 2021 May 24.

Published in final edited form as: J Parkinsons Dis. 2020; 10(2): 489–504. doi: 10.3233/JPD-191853

PMCID:: PMC8142388

Abstract Article PDF–1.3M

Select item 790881711.

Increased glutamate transmission onto dorsal striatum spiny projection neurons in Pink1 knockout rats

Rose B. Creed, Rosalinda C. Roberts, Charlene B. Farmer, Lori L. McMahon, Matthew S. Goldberg

Neurobiol Dis. Author manuscript; available in PMC 2022 Mar 1.

Published in final edited form as: Neurobiol Dis. 2021 Mar; 150: 105246. Published online 2020 Dec 30. doi: 10.1016/j.nbd.2020.105246

PMCID:: PMC7908817

Abstract Article PDF–2.2M

Select item 772531712.

Potential roles of neuronal nitric oxide synthase and the PTEN-induced kinase 1 (PINK1)/Parkin pathway for mitochondrial protein degradation in disuse-induced soleus muscle atrophy in adult rats

Munehiro Uda, Toshinori Yoshihara, Noriko Ichinoseki-Sekine, Takeshi Baba, Toshitada Yoshioka

PLoS One. 2020; 15(12): e0243660. Published online 2020 Dec 9. doi: 10.1371/journal.pone.0243660

PMCID:: PMC7725317

Abstract Article PDF–2.1M

Select item 759565613.

Hyperoxia exposure arrests alveolarization in neonatal rats via PTEN-induced putative kinase 1-Parkin and Nip3-like protein X-mediated mitophagy disorders

Xuefei Yu, Yanli Sun, Qing Cai, Xinyi Zhao, Ziyun Liu, Xindong Xue, Jianhua Fu

Int J Mol Med. 2020 Dec; 46(6): 2126–2136. Published online 2020 Oct 22. doi: 10.3892/ijmm.2020.4766

PMCID:: PMC7595656

Abstract Article PDF–2.0M

Select item 756737614.

Functional characterization of extrinsic tongue muscles in the Pink1-/- rat model of Parkinson disease

Tiffany J. Glass, Cynthia A. Kelm-Nelson, John C. Szot, Jacob M. Lake, Nadine P. Connor, Michelle R. Ciucci

PLoS One. 2020; 15(10): e0240366. Published online 2020 Oct 16. doi: 10.1371/journal.pone.0240366

PMCID:: PMC7567376

Abstract Article PDF–2.7M

Select item 751051115.

Enhanced susceptibility of PINK1 knockout rats to α-synuclein fibrils

Rose B. Creed, Matthew S. Goldberg

Neuroscience. Author manuscript; available in PMC 2021 Jun 15.

Published in final edited form as: Neuroscience. 2020 Jun 15; 437: 64–75. Published online 2020 Apr 27. doi: 10.1016/j.neuroscience.2020.04.032

PMCID:: PMC7510511

Abstract Article PDF–996K

Select item 730003816.

Psychological distress and lack of PINK1 promote bioenergetics alterations in peripheral blood mononuclear cells

Mariana Grigoruţă, Ruben K. Dagda, Ángel G. Díaz-Sánchez, Alejandro Martínez-Martínez

Sci Rep. 2020; 10: 9820. Published online 2020 Jun 17. doi: 10.1038/s41598-020-66745-9

PMCID:: PMC7300038

Abstract Article PDF–1.8M

Select item 688229617.

PTEN-Induced Putative Kinase 1 (PINK1)/Parkin-Mediated Mitophagy Protects PC12 Cells Against Cisplatin-Induced Neurotoxicity

Yao Zhang, Qingzhen Liu, Yongle Li, Caijuan Li, Yunhe Zhu, Fan Xia, Shiqin Xu, Weiyan Li

Med Sci Monit. 2019; 25: 8797–8806. Published online 2019 Nov 21. doi: 10.12659/MSM.918536

PMCID:: PMC6882296

Abstract Article PDF–2.4M

Select item 684877718.

Profiles of Brain Oxidative Damage, Ventricular Alterations, and Neurochemical Metabolites in the Striatum of PINK1 Knockout Rats as Functions of Age and Gender: Relevance to Parkinson Disease

Xiaojia Ren, Angela Hinchie, Aaron Swomley, David K. Powell, D. Allan Butterfield

Free Radic Biol Med. Author manuscript; available in PMC 2020 Nov 1.

Published in final edited form as: Free Radic Biol Med. 2019 Nov 1; 143: 146–152. Published online 2019 Aug 8. doi: 10.1016/j.freeradbiomed.2019.08.008

PMCID:: PMC6848777

Abstract Article PDF–1.1M

Select item 683185119.

Rewiring of the Human Mitochondrial Interactome during Neuronal Reprogramming Reveals Regulators of the Respirasome and Neurogenesis

Mohamed Taha Moutaoufik, Ramy Malty, Shahreen Amin, Qingzhou Zhang, Sadhna Phanse, Alla Gagarinova, Mara Zilocchi, Larissa Hoell, Zoran Minic, Maria Gagarinova, Hiroyuki Aoki, Jocelyn Stockwell, Matthew Jessulat, Florian Goebels, Kirsten Broderick, Nichollas E. Scott, James Vlasblom, Gabriel Musso, Bhanu Prasad, Eleonora Lamantea, Barbara Garavaglia, Alex Rajput, Kei Murayama, Yasushi Okazaki, Leonard J. Foster, Gary D. Bader, Francisco S. Cayabyab, Mohan Babu

iScience. 2019 Sep 27; 19: 1114–1132. Published online 2019 Sep 4. doi: 10.1016/j.isci.2019.08.057

PMCID:: PMC6831851

Abstract Article PDF–9.8M

Select item 658981020.

Laryngeal muscle biology in the Pink1−/− rat model of Parkinson disease

Tiffany J. Glass, Cynthia A. Kelm-Nelson, John A. Russell, John C. Szot, Jacob M. Lake, Nadine P. Connor, Michelle R. Ciucci

J Appl Physiol (1985) 2019 May 1; 126(5): 1326–1334. Published online 2019 Mar 7. doi: 10.1152/japplphysiol.00557.2018

PMCID:: PMC6589810

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