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Select item 112379301.

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein

Xiao Tang, Yang Liu, Jinhui Wang, Teng Long, Bobo Wing Yee Mok, Yan Huang, Ziqing Peng, Qinyu Jia, Chengxi Liu, Pui-Kin So, Sirius Pui-Kam Tse, Cheuk Hei NG, Shiyi Liu, Fei Sun, Shaojun Tang, Zhong-Ping Yao, Honglin Chen, Yusong Guo

J Biol Chem. 2024 Jun; 300(6): 107390. Published online 2024 May 21. doi: 10.1016/j.jbc.2024.107390

PMCID:: PMC11237930

Abstract Article PDF–3.8M

Select item 111584212.

RAF may induce cell proliferation through hypermethylation of tumor suppressor gene promoter in gastric epithelial cells

Xia Wang, Dan‐Feng Sun, Rong Lu, Zhao‐Fei Chen, Ying‐Xuan Chen, Jing‐Yuan Fang

Cancer Sci. 2009 Jan; 100(1): 117–125. Published online 2008 Nov 27. doi: 10.1111/j.1349-7006.2008.01017.x

PMCID:: PMC11158421

Abstract Article PDF–588K

Select item 111360083.

Back to the roots: the remarkable RAF oncogene story

A. Zebisch, J. Troppmair

Cell Mol Life Sci. 2006 Jun; 63(11): 1314–1330. Published online 2006 May 2. doi: 10.1007/s00018-006-6005-y

PMCID:: PMC11136008

Abstract Article PDF–418K

Select item 111158704.

The enhancement of antiproliferative and proapoptotic activity of HDAC inhibitors by curcumin is mediated by Hsp90 inhibition

Chiara Giommarelli, Valentina Zuco, Enrica Favini, Claudio Pisano, Fabrizio Dal Piaz, Nunziatina De Tommasi, Franco Zunino

Cell Mol Life Sci. 2010 Mar; 67(6): 995–1004. Published online 2009 Dec 29. doi: 10.1007/s00018-009-0233-x

PMCID:: PMC11115870

Abstract Article PDF–432K

Select item 109424675.

Mitochondrial Raf1 Regulates Glutamine Catabolism

Ronald L. Shanderson, Ian D. Ferguson, Zurab Siprashvili, Luca Ducoli, Albert M. Li, Weili Miao, Suhas Srinivasan, Mary Grace Velasco, Yang Li, Jiangbin Ye, Paul A. Khavari

Version 1. bioRxiv. Preprint. 2024 Mar 9. doi: 10.1101/2024.03.08.581297

PMCID:: PMC10942467

Abstract Article PDF–6.5M

Select item 108538026.

ESRP1 controls biogenesis and function of a large abundant multiexon circRNA

Dawei Liu, B Kate Dredge, Andrew G Bert, Katherine A Pillman, John Toubia, Wenting Guo, Boris J A Dyakov, Melodie M Migault, Vanessa M Conn, Simon J Conn, Philip A Gregory, Anne-Claude Gingras, Dinshaw Patel, Baixing Wu, Gregory J Goodall

Nucleic Acids Res. 2024 Feb 9; 52(3): 1387–1403. Published online 2023 Nov 28. doi: 10.1093/nar/gkad1138

PMCID:: PMC10853802

Abstract Article PDF–2.5M

Select item 107674307.

RAF1 mutation leading to hypertrophic cardiomyopathy in a Chinese family with a history of sudden cardiac death: A diagnostic insight into Noonan syndrome

Jingjing Zheng, Longyun Peng, Ruofei Cheng, Zhiyan Li, Jianjie Xie, Erwen Huang, Jianding Cheng, Qianhao Zhao

Mol Genet Genomic Med. 2024 Jan; 12(1): e2290. Published online 2023 Oct 3. doi: 10.1002/mgg3.2290

PMCID:: PMC10767430

Abstract Article PDF–8.9M

Select item 107415268.

PHI-1, an Endogenous Inhibitor Protein for Protein Phosphatase-1 and a Pan-Cancer Marker, Regulates Raf-1 Proteostasis

Jason A. Kirkbride, Garbo Young Nilsson, Jee In Kim, Kosuke Takeya, Yoshinori Tanaka, Hiroshi Tokumitsu, Futoshi Suizu, Masumi Eto

Biomolecules. 2023 Dec; 13(12): 1741. Published online 2023 Dec 4. doi: 10.3390/biom13121741

PMCID:: PMC10741526

Abstract Article PDF–3.0M

Select item 106277869.

ESYT1 tethers the ER to mitochondria and is required for mitochondrial lipid and calcium homeostasis

Alexandre Janer, Jordan L Morris, Michiel Krols, Hana Antonicka, Mari J Aaltonen, Zhen-Yuan Lin, Hanish Anand, Anne-Claude Gingras, Julien Prudent, Eric A Shoubridge

Life Sci Alliance. 2024 Jan; 7(1): e202302335. Published online 2023 Nov 6. doi: 10.26508/lsa.202302335

PMCID:: PMC10627786

Abstract Article PDF–5.2M

Select item 1061798110.

SND1 binds SARS-CoV-2 negative-sense RNA and promotes viral RNA synthesis through NSP9

Nora Schmidt, Sabina Ganskih, Yuanjie Wei, Alexander Gabel, Sebastian Zielinski, Hasmik Keshishian, Caleb A. Lareau, Liv Zimmermann, Jana Makroczyova, Cadence Pearce, Karsten Krey, Thomas Hennig, Sebastian Stegmaier, Lambert Moyon, Marc Horlacher, Simone Werner, Jens Aydin, Marco Olguin-Nava, Ramya Potabattula, Anuja Kibe, Lars Dölken, Redmond P. Smyth, Neva Caliskan, Annalisa Marsico, Christine Krempl, Jochen Bodem, Andreas Pichlmair, Steven A. Carr, Petr Chlanda, Florian Erhard, Mathias Munschauer

Cell. 2023 Oct 26; 186(22): 4834–4850.e23. doi: 10.1016/j.cell.2023.09.002

PMCID:: PMC10617981

Abstract Article

Select item 1055105111.

Matrix stiffness regulates tumor cell intravasation through expression and ESRP1-mediated alternative splicing of MENA

Wenjun Wang, Paul V. Taufalele, Martial Millet, Kevin Homsy, Kyra Smart, Emily D. Berestesky, Curtis T. Schunk, Matthew M. Rowe, Francois Bordeleau, Cynthia A. Reinhart-King

Cell Rep. Author manuscript; available in PMC 2023 Oct 23.

Published in final edited form as: Cell Rep. 2023 Apr 25; 42(4): 112338. Published online 2023 Apr 5. doi: 10.1016/j.celrep.2023.112338

PMCID:: PMC10551051

Abstract Article PDF–2.6M

Select item 1046704012.

Recurrent TRAK1::RAF1 Fusions in pediatric low‐grade gliomas

Jamal K. Benhamida, Hannah J. Harmsen, Deqin Ma, Christopher M. William, Bryan K. Li, Liliana Villafania, Purvil Sukhadia, Kerry A. Mullaney, Michael C. Dewan, Efsevia Vakiani, Matthias A. Karajannis, Matija Snuderl, David Zagzag, Marc Ladanyi, Marc K. Rosenblum, Tejus A. Bale

Brain Pathol. 2023 Sep; 33(5): e13185. Published online 2023 Jul 3. doi: 10.1111/bpa.13185

PMCID:: PMC10467040

Abstract Article PDF–1.4M

Select item 1039866013.

C9orf72 protein quality control by UBR5‐mediated heterotypic ubiquitin chains

Julia Jülg, Dieter Edbauer, Christian Behrends

EMBO Rep. 2023 Aug; 24(8): e55895. Published online 2023 Jun 15. doi: 10.15252/embr.202255895

PMCID:: PMC10398660

Abstract Article PDF–2.4M

Select item 1031806914.

TRIM22 promotes the proliferation of glioblastoma cells by activating MAPK signaling and accelerating the degradation of Raf-1

Xiaowei Fei, Ya-nan Dou, Kai Sun, Jialiang Wei, Qingdong Guo, Li Wang, Xiuquan Wu, Weihao Lv, Xiaofan Jiang, Zhou Fei

Exp Mol Med. 2023 Jun; 55(6): 1203–1217. Published online 2023 Jun 1. doi: 10.1038/s12276-023-01007-y

PMCID:: PMC10318069

Abstract Article PDF–7.6M

Select item 1028484015.

Molecular and cellular evidence for the impact of a hypertrophic cardiomyopathy-associated RAF1 variant on the structure and function of contractile machinery in bioartificial cardiac tissues

Saeideh Nakhaei-Rad, Fereshteh Haghighi, Farhad Bazgir, Julia Dahlmann, Alexandra Viktoria Busley, Marcel Buchholzer, Karolin Kleemann, Anne Schänzer, Andrea Borchardt, Andreas Hahn, Sebastian Kötter, Denny Schanze, Ruchika Anand, Florian Funk, Annette Vera Kronenbitter, Jürgen Scheller, Roland P. Piekorz, Andreas S. Reichert, Marianne Volleth, Matthew J. Wolf, Ion Cristian Cirstea, Bruce D. Gelb, Marco Tartaglia, Joachim P. Schmitt, Martina Krüger, Ingo Kutschka, Lukas Cyganek, Martin Zenker, George Kensah, Mohammad R. Ahmadian

Commun Biol. 2023; 6: 657. Published online 2023 Jun 21. doi: 10.1038/s42003-023-05013-8

PMCID:: PMC10284840

Abstract Article PDF–5.2M

Select item 1025238016.

LncRNA H19 Regulates Breast Cancer DNA Damage Response and Sensitivity to PARP Inhibitors via Binding to ILF2

Junsong Zhao, Junchao Xu, Mingming Wu, Wei Wang, Miaomiao Wang, Leiyan Yang, Huayong Cai, Qiao Xu, Ceshi Chen, Peter E. Lobie, Tao Zhu, Xinghua Han

Int J Mol Sci. 2023 Jun; 24(11): 9157. Published online 2023 May 23. doi: 10.3390/ijms24119157

PMCID:: PMC10252380

Abstract Article PDF–3.4M

Select item 1023742217.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 1018193618.

RAF1 contributes to cell proliferation and STAT3 activation in colorectal cancer independently of microsatellite and KRAS status

Coralie Dorard, Claire Madry, Olivier Buhard, Stefanie Toifl, Sebastian Didusch, Toky Ratovomanana, Quentin Letourneur, Helmut Dolznig, Mathew J. Garnett, Alex Duval, Manuela Baccarini

Oncogene. 2023; 42(20): 1649–1660. Published online 2023 Apr 5. doi: 10.1038/s41388-023-02683-w

PMCID:: PMC10181936

Abstract Article PDF–2.5M

Select item 1017768319.

SHOC2 mediates the drug-resistance of triple-negative breast cancer cells to everolimus

Wenwen Geng, Meiling Cao, Ke Dong, Junhua An, Haidong Gao

Cancer Biol Ther. 2023; 24(1): 2206362. Published online 2023 May 11. doi: 10.1080/15384047.2023.2206362

PMCID:: PMC10177683

Abstract Article PDF–2.5M

Select item 1016536220.

RAF1 deficiency causes a lethal syndrome that underscores RTK signaling during embryogenesis

Samantha Wong, Yu Xuan Tan, Abigail Yi Ting Loh, Kiat Yi Tan, Hane Lee, Zainab Aziz, Stanley F Nelson, Engin Özkan, Hülya Kayserili, Nathalie Escande‐Beillard, Bruno Reversade

EMBO Mol Med. 2023 May; 15(5): e17078. Published online 2023 Apr 17. doi: 10.15252/emmm.202217078

PMCID:: PMC10165362

Abstract Article PDF–2.7M

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