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Items: 1 to 20 of 555

1.
Polyubiquitinated PCNA triggers SLX4-mediated break-induced replication in alternative lengthening of telomeres (ALT) cancer cells
Sangin Kim, Su Hyung Park, Nalae Kang, Jae Sun Ra, Kyungjae Myung, Kyoo-young Lee
Nucleic Acids Res. 2024 Oct 28; 52(19): 11785–11805. Published online 2024 Sep 18. doi: 10.1093/nar/gkae785
PMCID:
PMC11514459
ArticlePDF–4.5M
2.
A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex
Marisa Bedir, Emily Outwin, Rita Colnaghi, Lydia Bassett, Iga Abramowicz, Mark O’Driscoll
EMBO Rep. 2024 Aug; 25(8): 3432–3455. Published online 2024 Jun 28. doi: 10.1038/s44319-024-00184-9
PMCID:
PMC11315929
ArticlePDF–3.4M
3.
DSBSO-Based XL-MS Analysis of Breast Cancer PDX Tissues to Delineate Protein Interaction Network in Clinical Samples
Fenglong Jiao, Clinton Yu, Andrew Wheat, Lijun Chen, Tung-Shing Mamie Lih, Hui Zhang, Lan Huang
J Proteome Res. Author manuscript; available in PMC 2024 Aug 3.
Published in final edited form as: J Proteome Res. 2024 Aug 2; 23(8): 3269–3279. Published online 2024 Feb 9. doi: 10.1021/acs.jproteome.3c00832
PMCID:
PMC11296914
ArticlePDF–1.7M
4.
Antagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability
Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold, Christopher E. Pearson
Cell. Author manuscript; available in PMC 2024 Oct 26.
Published in final edited form as: Cell. 2023 Oct 26; 186(22): 4898–4919.e25. Published online 2023 Oct 11. doi: 10.1016/j.cell.2023.09.008
PMCID:
PMC11209935
ArticlePDF–3.0M
5.
EIF3B stabilizes PCNA by counteracting SYVN1-mediated ubiquitination to serve as a promotor in cholangiocarcinoma
Ranglang Huang, Wanpin Nie, Liangliang Mi, Chenjiao Yao, Haixia Zhu
Aging (Albany NY) 2024 Apr 30; 16(8): 7311–7330. Published online 2024 Apr 29. doi: 10.18632/aging.205759
PMCID:
PMC11087095
ArticlePDF–2.6M
6.
Cryo-EM reveals a nearly complete PCNA loading process and unique features of the human alternative clamp loader CTF18-RFC
Qing He, Feng Wang, Michael E. O’Donnell, Huilin Li
Proc Natl Acad Sci U S A. 2024 Apr 30; 121(18): e2319727121. Published online 2024 Apr 26. doi: 10.1073/pnas.2319727121
PMCID:
PMC11067034
ArticlePDF–17M
7.
Mitochondrial Raf1 Regulates Glutamine Catabolism
Ronald L. Shanderson, Ian D. Ferguson, Zurab Siprashvili, Luca Ducoli, Albert M. Li, Weili Miao, Suhas Srinivasan, Mary Grace Velasco, Yang Li, Jiangbin Ye, Paul A. Khavari
Version 1. bioRxiv. Preprint. 2024 Mar 9. doi: 10.1101/2024.03.08.581297
PMCID:
PMC10942467
ArticlePDF–6.5M
8.
Checkpoint activation by Spd1: a competition-based system relying on tandem disordered PCNA binding motifs
Johan G Olsen, Andreas Prestel, Noah Kassem, Sebastian S Broendum, Hossain Mohammad Shamim, Signe Simonsen, Martin Grysbæk, Josefine Mortensen, Louise Lund Rytkjær, Gitte W Haxholm, Riccardo Marabini, Christian Holmberg, Antony M Carr, Ramon Crehuet, Olaf Nielsen, Birthe B Kragelund
Nucleic Acids Res. 2024 Feb 28; 52(4): 2030–2044. Published online 2024 Jan 23. doi: 10.1093/nar/gkae011
PMCID:
PMC10939359
ArticlePDF–2.6M
9.
Break induced replication orchestrates resection dependent template switch
Tianpeng Zhang, Yashpal Rawal, Haoyang Jiang, Youngho Kwon, Patrick Sung, Roger A. Greenberg
Nature. Author manuscript; available in PMC 2024 Mar 13.
Published in final edited form as: Nature. 2023 Jul; 619(7968): 201–208. Published online 2023 Jun 14. doi: 10.1038/s41586-023-06177-3
PMCID:
PMC10937050
ArticlePDF–4.2M
10.
Multisite phosphorylation dictates selective E2-E3 pairing as revealed by Ubc8/UBE2H-GID/CTLH assemblies
Jakub Chrustowicz, Dawafuti Sherpa, Jerry Li, Christine R. Langlois, Eleftheria C. Papadopoulou, D. Tung Vu, Laura A. Hehl, Özge Karayel, Viola Beier, Susanne von Gronau, Judith Müller, J. Rajan Prabu, Matthias Mann, Gary Kleiger, Arno F. Alpi, Brenda A. Schulman
Mol Cell. Author manuscript; available in PMC 2025 Jan 18.
Published in final edited form as: Mol Cell. 2024 Jan 18; 84(2): 293–308.e14. Published online 2023 Dec 18. doi: 10.1016/j.molcel.2023.11.027
PMCID:
PMC10843684
ArticlePDF–3.1M
11.
FANCD2-dependent mitotic DNA synthesis relies on PCNA K164 ubiquitination
Wendy Leung, Ryan M. Baxley, Emma Traband, Ya-Chu Chang, Colette B. Rogers, Liangjun Wang, Wesley Durrett, Kendall S. Bromley, Lidia Fiedorowicz, Tanay Thakar, Anika Tella, Alexandra Sobeck, Eric A. Hendrickson, George-Lucian Moldovan, Naoko Shima, Anja-Katrin Bielinsky
Cell Rep. Author manuscript; available in PMC 2024 Feb 5.
Published in final edited form as: Cell Rep. 2023 Dec 26; 42(12): 113523. Published online 2023 Dec 5. doi: 10.1016/j.celrep.2023.113523
PMCID:
PMC10842461
ArticlePDF–2.2M
12.
Molecular insight into the PCNA-binding mode of FBH1
Jiuyang Liu, Belén Chaves-Arquero, Pengcheng Wei, Adam H. Tencer, Antonio Ruiz-Albor, Gongyi Zhang, Francisco J. Blanco, Tatiana G. Kutateladze
Structure. Author manuscript; available in PMC 2024 May 4.
Published in final edited form as: Structure. 2023 May 4; 31(5): 511–517.e3. Published online 2023 Mar 28. doi: 10.1016/j.str.2023.03.004
PMCID:
PMC10727010
ArticlePDF–1.9M
13.
The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation
Xin Gu, Christopher Nardone, Nolan Kamitaki, Aoyue Mao, Stephen J. Elledge, Michael E. Greenberg
Science. Author manuscript; available in PMC 2023 Oct 31.
Published in final edited form as: Science. 2023 Aug 25; 381(6660): eadh5021. Published online 2023 Aug 25. doi: 10.1126/science.adh5021
PMCID:
PMC10617673
ArticlePDF–3.6M
14.
Short-range end resection requires ATAD5-mediated PCNA unloading for faithful homologous recombination
Su Hyung Park, Namwoo Kim, Nalae Kang, Eunjin Ryu, Eun A Lee, Jae Sun Ra, Anton Gartner, Sukhyun Kang, Kyungjae Myung, Kyoo-young Lee
Nucleic Acids Res. 2023 Oct 27; 51(19): 10519–10535. Published online 2023 Sep 22. doi: 10.1093/nar/gkad776
PMCID:
PMC10602867
ArticlePDF–2.2M
15.
Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates
Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert
Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644
PMCID:
PMC10565876
ArticlePDF–3.7M
16.
PCNA recruits cohesin loader Scc2 to ensure sister chromatid cohesion
Ivan Psakhye, Ryotaro Kawasumi, Takuya Abe, Kouji Hirota, Dana Branzei
Nat Struct Mol Biol. 2023; 30(9): 1286–1294. Published online 2023 Aug 17. doi: 10.1038/s41594-023-01064-x
PMCID:
PMC10497406
ArticlePDF–9.2M
17.
Mapping the MOB proteins’ proximity network reveals a unique interaction between human MOB3C and the RNase P complex
Islam E. Elkholi, Jonathan Boulais, Marie-Pier Thibault, Hong-Duc Phan, Amélie Robert, Lien B. Lai, Denis Faubert, Matthew J. Smith, Venkat Gopalan, Jean-Franҫois Côté
J Biol Chem. 2023 Sep; 299(9): 105123. Published online 2023 Aug 1. doi: 10.1016/j.jbc.2023.105123
PMCID:
PMC10480535
ArticlePDF–2.4M
18.
High-sensitivity profiling of SARS-CoV-2 noncoding region–host protein interactome reveals the potential regulatory role of negative-sense viral RNA
Liuyiqi Jiang, Mu Xiao, Qing-Qing Liao, Luqian Zheng, Chunyan Li, Yuemei Liu, Bing Yang, Aiming Ren, Chao Jiang, Xin-Hua Feng
mSystems. 2023 Jul-Aug; 8(4): e00135-23. Published online 2023 Jun 14. doi: 10.1128/msystems.00135-23
PMCID:
PMC10469612
ArticlePDF–4.0M
19.
RNAPII-dependent ATM signaling at collisions with replication forks
Elias Einig, Chao Jin, Valentina Andrioletti, Boris Macek, Nikita Popov
Nat Commun. 2023; 14: 5147. Published online 2023 Aug 24. doi: 10.1038/s41467-023-40924-4
PMCID:
PMC10449895
ArticlePDF–2.2M
20.
Some aspects of the life of SARS-CoV-2 ORF3a protein in mammalian cells
Song Jiao, Pablo Miranda, Yan Li, Dragan Maric, Miguel Holmgren
Heliyon. 2023 Aug; 9(8): e18754. Published online 2023 Aug 1. doi: 10.1016/j.heliyon.2023.e18754
PMCID:
PMC10440475
ArticlePDF–8.9M

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