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Select item 49948731.

WNK1 kinase balances T cell adhesion versus migration in vivo

Robert Köchl, Flavian Thelen, Lesley Vanes, Tiago F. Brazao, Kathryn Fountain, Jian Xie, Chou-Long Huang, Ruth Lyck, Jens V. Stein, Victor L. J. Tybulewicz

Nat Immunol. Author manuscript; available in PMC 2017 Mar 1.

Published in final edited form as: Nat Immunol. 2016 Sep; 17(9): 1075–1083. Published online 2016 Jul 11. doi: 10.1038/ni.3495

Correction in:: Nat Immunol. 2017 Jan 19; 18(2): 246.

PMCID:: PMC4994873

Abstract Article PDF–2.3M

Select item 40623012.

In vitro membrane reconstitution of the T cell receptor proximal signaling network

Enfu Hui, Ronald D. Vale

Nat Struct Mol Biol. Author manuscript; available in PMC 2014 Aug 1.

Published in final edited form as: Nat Struct Mol Biol. 2014 Feb; 21(2): 133–142. Published online 2014 Jan 26. doi: 10.1038/nsmb.2762

PMCID:: PMC4062301

Abstract Article PDF–1.7M

Select item 37051093.

Identification of the dichotomous role of age-related LCK in calorie restriction revealed by integrative analysis of cDNA microarray and interactome

Daeui Park, Eun Kyeong Lee, Eun Jee Jang, Hyoung Oh Jeong, Byoung-Chul Kim, Young Mi Ha, Seong Eui Hong, Byung Pal Yu, Hae Young Chung

Age (Dordr) 2013 Aug; 35(4): 1045–1060. Published online 2012 Jul 25. doi: 10.1007/s11357-012-9426-6

PMCID:: PMC3705109

Abstract Article PDF–743K

Select item 36742764.

Lck tyrosine kinase mediates β1-integrin signalling to regulate Schwann cell migration and myelination

Jennifer K. Ness, Kristin M. Snyder, Nikos Tapinos

Nat Commun. 2013 May 28; 4: 1912. Published online 2013 May 28. doi: 10.1038/ncomms2928

PMCID:: PMC3674276

Abstract Article PDF–5.7M

Select item 32260065.

T cell protein tyrosine phosphatase attenuates T cell signaling to maintain tolerance in mice

Florian Wiede, Benjamin J. Shields, Sock Hui Chew, Konstantinos Kyparissoudis, Catherine van Vliet, Sandra Galic, Michel L. Tremblay, Sarah M. Russell, Dale I. Godfrey, Tony Tiganis

J Clin Invest. 2011 Dec 1; 121(12): 4758–4774. Published online 2011 Nov 14. doi: 10.1172/JCI59492

Correction in:: J Clin Invest. 2023 Oct 16; 133(20): e175163.

PMCID:: PMC3226006

Abstract Article PDF–4.7M

Select item 31780596.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 30984877.

LKB1 regulates TCR-mediated PLCγ1 activation and thymocyte positive selection

Yonghao Cao, Hai Li, Haifeng Liu, Min Zhang, Zichun Hua, Hongbin Ji, Xiaolong Liu

EMBO J. 2011 May 18; 30(10): 2083–2093. Published online 2011 Apr 12. doi: 10.1038/emboj.2011.116

PMCID:: PMC3098487

Abstract Article PDF–1.8M

Select item 30897698.

Role of Non-receptor Protein Tyrosine Kinases During Phospholipase C-γ1 Related Uterine Contractions in the Rat

Mark Phillippe, Leigh M. Sweet, Diana F. Bradley, Daniel Engle

Reprod Sci. Author manuscript; available in PMC 2011 May 7.

Published in final edited form as: Reprod Sci. 2009 Mar; 16(3): 265–273. doi: 10.1177/1933719108327598

PMCID:: PMC3089769

Abstract Article PDF–2.0M

Select item 30742029.

Regulation of GATA-3 expression during CD4 lineage differentiation

Idoia Gimferrer, Taishan Hu, Amie Simmons, Chi Wang, Abdallah Souabni, Meinrad Busslinger, Timothy P. Bender, Gabriela Hernandez-Hoyos, José Alberola-Ila

J Immunol. Author manuscript; available in PMC 2012 Apr 1.

Published in final edited form as: J Immunol. 2011 Apr 1; 186(7): 3892–3898. Published online 2011 Feb 25. doi: 10.4049/jimmunol.1003505

PMCID:: PMC3074202

Abstract Article PDF–1.3M

Select item 306231210.

Strong CD28 costimulation suppresses induction of regulatory T cells from naive precursors through Lck signaling

Kenrick Semple, Antony Nguyen, Yu Yu, Honglin Wang, Claudio Anasetti, Xue-Zhong Yu

Blood. 2011 Mar 17; 117(11): 3096–3103. Prepublished online 2011 Jan 18. doi: 10.1182/blood-2010-08-301275

PMCID:: PMC3062312

Abstract Article

Select item 291166111.

Tarp regulates early Chlamydia-induced host cell survival through interactions with the human adaptor protein SHC1

Adrian Mehlitz, Sebastian Banhart, André P. Mäurer, Alexis Kaushansky, Andrew G. Gordus, Julia Zielecki, Gavin MacBeath, Thomas F. Meyer

J Cell Biol. 2010 Jul 12; 190(1): 143–157. doi: 10.1083/jcb.200909095

PMCID:: PMC2911661

Abstract Article PDF–3.2M

Select item 284417512.

SOCS-6 Negatively Regulates T Cell Activation through Targeting p56^lck to Proteasomal Degradation

Young Bong Choi, Myoungsun Son, Mijin Park, Jaekyoon Shin, Yungdae Yun

J Biol Chem. 2010 Mar 5; 285(10): 7271–7280. Published online 2009 Dec 10. doi: 10.1074/jbc.M109.073726

PMCID:: PMC2844175

Abstract Article PDF–1.4M

Select item 227071913.

Heather J. Hosea, Edward S. Rector, Carla G. Taylor

Clin Dev Immunol. 2005 Mar; 12(1): 75–84. doi: 10.1080/17402520400017393

PMCID:: PMC2270719

Summary PDF–557K

Select item 219396914.

Regulation of Fyn Through Translocation of Activated Lck into Lipid Rafts

Dominik Filipp, Jenny Zhang, Bernadine L. Leung, Andrey Shaw, Steven D. Levin, André Veillette, Michael Julius

J Exp Med. 2003 May 5; 197(9): 1221–1227. doi: 10.1084/jem.20022112

PMCID:: PMC2193969

Abstract Article PDF–240K

Select item 219182315.

Impaired development of V gamma 3 dendritic epidermal T cells in p56lck protein tyrosine kinase-deficient and CD45 protein tyrosine phosphatase- deficient mice

J Exp Med. 1995 Jan 1; 181(1): 345–349. doi: 10.1084/jem.181.1.345

PMCID:: PMC2191823

Summary PDF–619K

Select item 211999316.

Distinct intracellular localization of Lck and Fyn protein tyrosine kinases in human T lymphocytes

J Cell Biol. 1994 May 1; 125(3): 639–649. doi: 10.1083/jcb.125.3.639

PMCID:: PMC2119993

Summary PDF–2.2M

Select item 121761617.

The SH3 domain of Src tyrosyl protein kinase interacts with the N-terminal splice region of the PDE4A cAMP-specific phosphodiesterase RPDE-6 (RNPDE4A5).

J C O'Connell, J F McCallum, I McPhee, J Wakefield, E S Houslay, W Wishart, G Bolger, M Frame, M D Houslay

Biochem J. 1996 Aug 15; 318(Pt 1): 255–261. doi: 10.1042/bj3180255

PMCID:: PMC1217616

Summary PDF–419K

Select item 117095118.

Kit signaling through PI 3-kinase and Src kinase pathways: an essential role for Rac1 and JNK activation in mast cell proliferation.

I Timokhina, H Kissel, G Stella, P Besmer

EMBO J. 1998 Nov 2; 17(21): 6250–6262. doi: 10.1093/emboj/17.21.6250

PMCID:: PMC1170951

Summary PDF–518K

Select item 36481219.

The SH3 domain of p56lck is involved in binding to phosphatidylinositol 3'-kinase from T lymphocytes.

L B Vogel, D J Fujita

Mol Cell Biol. 1993 Dec; 13(12): 7408–7417. doi: 10.1128/mcb.13.12.7408

PMCID:: PMC364812

Summary Page Browse PDF–2.7M

Select item 28711420.

The CD4 and CD8 antigens are coupled to a protein-tyrosine kinase (p56lck) that phosphorylates the CD3 complex.

E K Barber, J D Dasgupta, S F Schlossman, J M Trevillyan, C E Rudd

Proc Natl Acad Sci U S A. 1989 May; 86(9): 3277–3281. doi: 10.1073/pnas.86.9.3277

PMCID:: PMC287114

Summary Page Browse PDF–1.4M

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