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Select item 106199051.

STAT1 deficiency underlies a proinflammatory imprint of naive CD4⁺ T cells in spondyloarthritis

Bilade Cherqaoui, Frédéric Crémazy, Marc Lauraine, Ghazal Shammas, Roula Said-Nahal, Hendrick Mambu Mambueni, Félicie Costantino, Marine Fourmont, Audrey Hulot, Henri-Jean Garchon, Simon Glatigny, Luiza M. Araujo, Maxime Breban

Front Immunol. 2023; 14: 1227281. Published online 2023 Oct 18. doi: 10.3389/fimmu.2023.1227281

PMCID:: PMC10619905

Abstract Article PDF–7.0M

Select item 102917792.

The transcription factor Stat-1 is essential for Schwann cell differentiation, myelination and myelin sheath regeneration

Jinghui Xu, Bin Zhang, Jieyi Cai, Qianqian Peng, Junxia Hu, Parizat Askar, Jianghong Shangguan, Wenfeng Su, Changlai Zhu, Hualin Sun, Songlin Zhou, Gang Chen, Xiaoming Yang, Yun Gu

Mol Med. 2023; 29: 79. Published online 2023 Jun 26. doi: 10.1186/s10020-023-00667-w

PMCID:: PMC10291779

Abstract Article PDF–23M

Select item 75401413.

Identification of immune checkpoint inhibitors and biomarkers among STAT family in stomach adenocarcinoma

Lili Guo, Te Fang, Yanhua Jiang, Dingsheng Liu

Am J Transl Res. 2020; 12(9): 4977–4997. Published online 2020 Sep 15.

PMCID:: PMC7540141

Abstract Article PDF–11M

Select item 74129084.

STAT1 regulates interferon-γ-induced angiotensinogen and MCP-1 expression in a bidirectional manner in primary cultured mesangial cells

Harrison M Penrose, Akemi Katsurada, Kayoko Miyata, Maki Urushihara, Ryousuke Satou

J Renin Angiotensin Aldosterone Syst. 2020 Jul-Sep; 21(3): 1470320320946527. Published online 2020 Aug 3. doi: 10.1177/1470320320946527

PMCID:: PMC7412908

Abstract Article PDF–1.4M

Select item 53760965.

Functional Selectivity in Cytokine Signaling Revealed Through a Pathogenic EPO Mutation

Ah Ram Kim, Jacob C. Ulirsch, Stephan Wilmes, Ekrem Unal, Ignacio Moraga, Musa Karakukcu, Daniel Yuan, Shideh Kazerounian, Nour J. Abdulhay, David S. King, Namrata Gupta, Stacey B. Gabriel, Eric S. Lander, Turkan Patiroglu, Alper Ozcan, Mehmet Akif Ozdemir, K. Christopher Garcia, Jacob Piehler, Hanna T. Gazda, Daryl E. Klein, Vijay G. Sankaran

Cell. Author manuscript; available in PMC 2018 Mar 9.

Published in final edited form as: Cell. 2017 Mar 9; 168(6): 1053–1064.e15. doi: 10.1016/j.cell.2017.02.026

PMCID:: PMC5376096

Abstract Article PDF–1.4M

Select item 53700116.

Activation of PI3K in response to high glucose leads to regulation of SOCS-3 and STAT1/3 signals and induction of glomerular mesangial extracellular matrix formation

Meei-Ling Sheu, Chin-Chang Shen, Jia-Rong Jheng, Chih-Kang Chiang

Oncotarget. 2017 Mar 7; 8(10): 16925–16938. Published online 2017 Jan 24. doi: 10.18632/oncotarget.14808

PMCID:: PMC5370011

Abstract Article PDF–4.7M

Select item 52909527.

Signal Transducer and Activator of Transcription 1 Plays a Pivotal Role in RET/PTC3 Oncogene-induced Expression of Indoleamine 2,3-Dioxygenase 1

Sonia Moretti, Elisa Menicali, Nicole Nucci, Pasquale Voce, Renato Colella, Rosa Marina Melillo, Federica Liotti, Silvia Morelli, Francesca Fallarino, Antonio Macchiarulo, Massimo Santoro, Nicola Avenia, Efisio Puxeddu

J Biol Chem. 2017 Feb 3; 292(5): 1785–1797. Published online 2016 Dec 19. doi: 10.1074/jbc.M116.745448

PMCID:: PMC5290952

Abstract Article PDF–1.7M

Select item 52280998.

Zinc deficiency affects the STAT1/3 signaling pathways in part through redox-mediated mechanisms

S. Supasai, L. Aimo, A.M. Adamo, G.G. Mackenzie, P.I. Oteiza

Redox Biol. 2017 Apr; 11: 469–481. Published online 2017 Jan 3. doi: 10.1016/j.redox.2016.12.027

PMCID:: PMC5228099

Abstract Article PDF–2.2M

Select item 50955329.

PARP9 and PARP14 cross-regulate macrophage activation via STAT1 ADP-ribosylation

Hiroshi Iwata, Claudia Goettsch, Amitabh Sharma, Piero Ricchiuto, Wilson Wen Bin Goh, Arda Halu, Iwao Yamada, Hideo Yoshida, Takuya Hara, Mei Wei, Noriyuki Inoue, Daiju Fukuda, Alexander Mojcher, Peter C. Mattson, Albert-László Barabási, Mark Boothby, Elena Aikawa, Sasha A. Singh, Masanori Aikawa

Nat Commun. 2016; 7: 12849. Published online 2016 Oct 31. doi: 10.1038/ncomms12849

PMCID:: PMC5095532

Abstract Article PDF–4.6M

Select item 497239710.

E-cadherin interactome complexity and robustness resolved by quantitative proteomics

Zhenhuan Guo, Lisa J Neilson, Hang Zhong, Paul S Murray, Megha Vaman Rao, Sara Zanivan, Ronen Zaidel-Bar

Sci Signal. Author manuscript; available in PMC 2016 Aug 3.

Published in final edited form as: Sci Signal. 2014 Dec 2; 7(354): rs7. Published online 2014 Dec 2. doi: 10.1126/scisignal.2005473

PMCID:: PMC4972397

Abstract Article PDF–3.1M

Select item 465307411.

PARP9-DTX3L ubiquitin ligase targets host histone H2BJ and viral 3C protease to enhance interferon signaling and control viral infection

Yong Zhang, Dailing Mao, William T Roswit, Xiaohua Jin, Anand C Patel, Dhara A Patel, Eugene Agapov, Zhepeng Wang, Rose M Tidwell, Jeffrey J Atkinson, Guangming Huang, Ronald McCarthy, Jinsheng Yu, Nadezhda E Yun, Slobodan Paessler, T Glen Lawson, Natalie S Omattage, Tom J Brett, Michael J Holtzman

Nat Immunol. 2015; 16(12): 1215–1227. Published online 2015 Dec 1. doi: 10.1038/ni.3279

PMCID:: PMC4653074

Abstract Article PDF–2.9M

Select item 465127312.

Aerosolized STAT1 Antisense Oligodeoxynucleotides Decrease the Concentrations of Inflammatory Mediators in Bronchoalveolar Lavage Fluid in Bleomycin-Induced Rat Pulmonary Fibrosis

Ming Zeng, Bin Liao, Chen Zhu, Wenjun Wang, Xiaoqin Zhan, Xianming Fan

Cell Mol Immunol. 2008 Jun; 5(3): 219–224. doi: 10.1038/cmi.2008.27

PMCID:: PMC4651273

Abstract PDF–409K

Select item 463758013.

Bone marrow mesenchymal stromal cells with CD47 high expression via the signal transducer and activators of transcription signaling pathway preventing myocardial fibrosis

Wei Deng, Qing-Wei Chen, Xing-Sheng Li, Zhong-Ming Yuan, Gui-Qiong Li, Da-Zhi Ke, Li Wang, Zhi-Qing Wu, Shi-Lan Luo

Int J Clin Exp Pathol. 2015; 8(9): 10555–10564. Published online 2015 Sep 1.

PMCID:: PMC4637580

Abstract Article PDF–718K

Select item 454728514.

Roles of unphosphorylated ISGF3 in HCV infection and interferon responsiveness

Pil Soo Sung, HyeonJoo Cheon, Chung Hwan Cho, Seon-Hui Hong, Do Youn Park, Hyung-Il Seo, Su-Hyung Park, Seung Kew Yoon, George R. Stark, Eui-Cheol Shin

Proc Natl Acad Sci U S A. 2015 Aug 18; 112(33): 10443–10448. Published online 2015 Jul 27. doi: 10.1073/pnas.1513341112

PMCID:: PMC4547285

Abstract Article PDF–1.5M

Select item 431599215.

Activation of JAK-STAT pathway is required for platelet-derived growth factor-induced proliferation of pancreatic stellate cells

Atsushi Masamune, Masahiro Satoh, Kazuhiro Kikuta, Noriaki Suzuki, Tooru Shimosegawa

World J Gastroenterol. 2005 Jun 14; 11(22): 3385–3391. Published online 2005 Jun 14. doi: 10.3748/wjg.v11.i22.3385

PMCID:: PMC4315992

Abstract Article PDF–528K

Select item 411401916.

Unanchored K48-linked poly-ubiquitin synthesized by the E3-ubiquitin ligase TRIM6 stimulates the interferon-IKKε kinase mediated antiviral response

Ricardo Rajsbaum, Gijs A. Versteeg, Sonja Schmid, Ana M. Maestre, Alan Belicha-Villanueva, Carles Martínez-Romero, Jenish R. Patel, Juliet Morrison, Giuseppe Pisanelli, Lisa Miorin, Maudry Laurent-Rolle, Hong M. Moulton, David A. Stein, Ana Fernandez-Sesma, Benjamin R. tenOever, Adolfo García-Sastre

Immunity. Author manuscript; available in PMC 2015 Jun 19.

Published in final edited form as: Immunity. 2014 Jun 19; 40(6): 880–895. Published online 2014 May 29. doi: 10.1016/j.immuni.2014.04.018

PMCID:: PMC4114019

Abstract Article PDF–2.7M

Select item 405627517.

TLR ligands up-regulate Trex1 expression in murine conventional dendritic cells through type I Interferon and NF-κB-dependent signaling pathways

Jun Xu, Philip W. Zoltick, Ana M. Gamero, Stefania Gallucci

J Leukoc Biol. 2014 Jul; 96(1): 93–103. doi: 10.1189/jlb.2A0713-393RR

PMCID:: PMC4056275

Abstract Article

Select item 394085718.

The signal transducers Stat1 and Stat3 and their novel target Jmjd3 drive the expression of inflammatory genes in microglia

Piotr Przanowski, Michal Dabrowski, Aleksandra Ellert-Miklaszewska, Michal Kloss, Jakub Mieczkowski, Beata Kaza, Anna Ronowicz, Feng Hu, Arkadiusz Piotrowski, Helmut Kettenmann, Jan Komorowski, Bozena Kaminska

J Mol Med (Berl) 2014; 92(3): 239–254. Published online 2013 Oct 6. doi: 10.1007/s00109-013-1090-5

PMCID:: PMC3940857

Abstract Article PDF–1.1M

Select item 392000719.

NF-κB and STAT1 control CXCL1 and CXCL2 gene transcription

Susan J. Burke, Danhong Lu, Tim E. Sparer, Thomas Masi, Matthew R. Goff, Michael D. Karlstad, J. Jason Collier

Am J Physiol Endocrinol Metab. 2014 Jan 15; 306(2): E131–E149. Published online 2013 Nov 26. doi: 10.1152/ajpendo.00347.2013

PMCID:: PMC3920007

Abstract Article

Select item 381102220.

Isolation of Mammalian 26S Proteasomes and p97/VCP Complexes Using the Ubiquitin-like Domain from HHR23B Reveals Novel Proteasome-Associated Proteins

Henrike C. Besche, Wilhelm Haas, Steven P. Gygi, Alfred L. Goldberg

Biochemistry. Author manuscript; available in PMC 2013 Oct 29.

Published in final edited form as: Biochemistry. 2009 Mar 24; 48(11): 10.1021/bi802198q. doi: 10.1021/bi802198q

PMCID:: PMC3811022

Abstract Article PDF–3.7M

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