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Select item 67407051.

Calmodulin Binds to the C Terminus of Sodium Channels Na_v1.4 and Na_v1.6 and Differentially Modulates Their Functional Properties

Raimund I. Herzog, Chuanju Liu, Stephen G. Waxman, Theodore R. Cummins

J Neurosci. 2003 Sep 10; 23(23): 8261–8270. doi: 10.1523/JNEUROSCI.23-23-08261.2003

PMCID:: PMC6740705

Abstract Article PDF–328K

Select item 53475712.

Mapping of voltage sensor positions in resting and inactivated mammalian sodium channels by LRET

Tomoya Kubota, Thomas Durek, Bobo Dang, Rocio K. Finol-Urdaneta, David J. Craik, Stephen B. H. Kent, Robert J. French, Francisco Bezanilla, Ana M. Correa

Proc Natl Acad Sci U S A. 2017 Mar 7; 114(10): E1857–E1865. Published online 2017 Feb 15. doi: 10.1073/pnas.1700453114

PMCID:: PMC5347571

Abstract Article PDF–1.8M

Select item 46758203.

Important Role of Asparagines in Coupling the Pore and Votage-Sensor Domain in Voltage-Gated Sodium Channels

Michael F. Sheets, Harry A. Fozzard, Dorothy A. Hanck

Biophys J. 2015 Dec 1; 109(11): 2277–2286. Published online 2015 Dec 1. doi: 10.1016/j.bpj.2015.10.012

PMCID:: PMC4675820

Abstract Article PDF–1.0M

Select item 41368384.

Molecular Dynamics Study of Binding of µ-Conotoxin GIIIA to the Voltage-Gated Sodium Channel Na_v1.4

Somayeh Mahdavi, Serdar Kuyucak

PLoS One. 2014; 9(8): e105300. Published online 2014 Aug 18. doi: 10.1371/journal.pone.0105300

PMCID:: PMC4136838

Abstract Article PDF–4.4M

Select item 35624585.

Multiple pore conformations driven by asynchronous movements of voltage sensors in a eukaryotic sodium channel

Marcel P. Goldschen-Ohm, Deborah L. Capes, Kevin M. Oelstrom, Baron Chanda

Nat Commun. 2013 Jan 15; 4: 1350. Published online 2013 Jan 15. doi: 10.1038/ncomms2356

PMCID:: PMC3562458

Abstract Article PDF–2.0M

Select item 34276606.

Effect of SkM1 Sodium Channels Delivered Via a Cell Platform on Cardiac Conduction and Arrhythmia Induction

Gerard J.J. Boink, Jia Lu, Helen E. Driessen, Lian Duan, Eugene A. Sosunov, Evgeny P. Anyukhovsky, Iryna N. Shlapakova, David H. Lau, Tove S. Rosen, Peter Danilo, Zhiheng Jia, Nazira Ozgen, Yevgeniy Bobkov, Yuanjian Guo, Peter R. Brink, Yelena Kryukova, Richard B. Robinson, Emilia Entcheva, Ira S. Cohen, Michael R. Rosen

Circ Arrhythm Electrophysiol. Author manuscript; available in PMC 2013 Aug 1.

Published in final edited form as: Circ Arrhythm Electrophysiol. 2012 Aug 1; 5(4): 831–840. Published online 2012 Jun 21. doi: 10.1161/CIRCEP.111.969907

PMCID:: PMC3427660

Abstract Article PDF–2.1M

Select item 34104087.

SkM1 and Cx32 improve conduction in canine myocardial infarcts yet only SkM1 is antiarrhythmic

Gerard J.J. Boink, David H. Lau, Iryna N. Shlapakova, Eugene A. Sosunov, Evgeny P. Anyukhovsky, Helen E. Driessen, Wen Dun, Ming Chen, Peter Danilo, Jr, Tove S. Rosen, Nazira Őzgen, Heather S. Duffy, Yelena Kryukova, Penelope A Boyden, Richard B. Robinson, Peter R. Brink, Ira S. Cohen, Michael R. Rosen

Cardiovasc Res. 2012 Jun 1; 94(3): 450–459. Published online 2012 Feb 27. doi: 10.1093/cvr/cvs107

PMCID:: PMC3410408

Abstract Article PDF–576K

Select item 31954708.

A sodium channel knockin mutant (Na_V1.4-R669H) mouse model of hypokalemic periodic paralysis

Fenfen Wu, Wentao Mi, Dennis K. Burns, Yu Fu, Hillery F. Gray, Arie F. Struyk, Stephen C. Cannon

J Clin Invest. 2011 Oct 3; 121(10): 4082–4094. Published online 2011 Sep 1. doi: 10.1172/JCI57398

PMCID:: PMC3195470

Abstract Article PDF–2.7M

Select item 31780599.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 305220810.

Open- and closed-state fast inactivation in sodium channels: Differential effects of a site-3 anemone toxin

James R Groome, Frank Lehmann-Horn, Boris D Holzherr

Channels (Austin) 2011 Jan-Feb; 5(1): 65–78. Published online 2011 Jan 1. doi: 10.4161/chan.5.1.14031

PMCID:: PMC3052208

Abstract Article PDF–1.6M

Select item 299813411.

A Molecular Switch between the Outer and the Inner Vestibules of the Voltage-gated Na⁺ Channel

Touran Zarrabi, Rene Cervenka, Walter Sandtner, Peter Lukacs, Xaver Koenig, Karlheinz Hilber, Markus Mille, Gregory M. Lipkind, Harry A. Fozzard, Hannes Todt

J Biol Chem. 2010 Dec 10; 285(50): 39458–39470. Published online 2010 Oct 6. doi: 10.1074/jbc.M110.132886

PMCID:: PMC2998134

Abstract Article PDF–2.9M

Select item 291206912.

Ion permeation and block of the gating pore in the voltage sensor of Na_V1.4 channels with hypokalemic periodic paralysis mutations

Stanislav Sokolov, Todd Scheuer, William A. Catterall

J Gen Physiol. 2010 Aug; 136(2): 225–236. doi: 10.1085/jgp.201010414

PMCID:: PMC2912069

Abstract Article PDF–1.5M

Select item 290710513.

µ-Conotoxin KIIIA Derivatives with Divergent Affinities versus Efficacies in Blocking Voltage-gated Sodium Channels

Min-Min Zhang, Tiffany S. Han, Baldomero M. Olivera, Grzegorz Bulaj, Doju Yoshikami

Biochemistry. Author manuscript; available in PMC 2011 Jun 15.

Published in final edited form as: Biochemistry. 2010 Jun 15; 49(23): 4804–4812. doi: 10.1021/bi100207k

PMCID:: PMC2907105

Abstract Article PDF–675K

Select item 263913114.

Expression of skeletal but not cardiac Na⁺ channel isoform preserves normal conduction in a depolarized cardiac syncytium

Lev Protas, Wen Dun, Zhiheng Jia, Jia Lu, Annalisa Bucchi, Sindhu Kumari, Ming Chen, Ira S. Cohen, Michael R. Rosen, Emilia Entcheva, Richard B. Robinson

Cardiovasc Res. 2009 Feb 15; 81(3): 528–535. Published online 2008 Oct 31. doi: 10.1093/cvr/cvn290