PMC Links for GEO Profiles (Select 117225347) - PMC

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Items: 14

Select item 56367841.

MKK6 controls T3-mediated browning of white adipose tissue

Nuria Matesanz, Edgar Bernardo, Rebeca Acín-Pérez, Elisa Manieri, Sonia Pérez-Sieira, Lourdes Hernández-Cosido, Valle Montalvo-Romeral, Alfonso Mora, Elena Rodríguez, Luis Leiva-Vega, Ana Victoria Lechuga-Vieco, Jesús Ruiz-Cabello, Jorge L. Torres, Maria Crespo-Ruiz, Francisco Centeno, Clara V. Álvarez, Miguel Marcos, Jose Antonio Enríquez, Ruben Nogueiras, Guadalupe Sabio

Nat Commun. 2017; 8: 856. Published online 2017 Oct 11. doi: 10.1038/s41467-017-00948-z

PMCID:: PMC5636784

Abstract Article PDF–1.9M

Select item 37435022.

Precisely Ordered Phosphorylation Reactions in the p38 Mitogen-activated Protein (MAP) Kinase Cascade

John M. Humphreys, Alexander T. Piala, Radha Akella, Haixia He, Elizabeth J. Goldsmith

J Biol Chem. 2013 Aug 9; 288(32): 23322–23330. Published online 2013 Jun 6. doi: 10.1074/jbc.M113.462101

PMCID:: PMC3743502

Abstract Article PDF–2.2M

Select item 36916793.

Overexpression of Mitogen-activated Protein Kinase Kinase 6 in the Heart Improves Functional Recovery from Ischemia in Vitro and Protects against Myocardial Infarction in Vivo

Joshua J. Martindale, Jason A. Wall, Diana M. Martinez-Longoria, Prafulla Aryal, Howard A. Rockman, Yiru Guo, Roberto Bolli, Christopher C. Glembotski

J Biol Chem. Author manuscript; available in PMC 2013 Jun 25.

Published in final edited form as: J Biol Chem. 2005 Jan 7; 280(1): 669–676. Published online 2004 Oct 18. doi: 10.1074/jbc.M406690200

PMCID:: PMC3691679

Abstract Article PDF–2.1M

Select item 36895394.

The Structure of the MAP2K MEK6 Reveals an Autoinhibitory Dimer

Xiaoshan Min, Radha Akella, Haixia He, John M. Humphreys, Susan E. Tsutakawa, Seung-Jae Lee, John A. Tainer, Melanie H. Cobb, Elizabeth J. Goldsmith

Structure. Author manuscript; available in PMC 2013 Jun 21.

Published in final edited form as: Structure. 2009 Jan 14; 17(1): 96–104. doi: 10.1016/j.str.2008.11.007

PMCID:: PMC3689539

Abstract Article PDF–1.8M

Select item 35339105.

Pro-life role for c-Jun N-terminal kinase and p38 mitogen-activated protein kinase at rostral ventrolateral medulla in experimental brain stem death

Alice YW Chang

J Biomed Sci. 2012; 19(1): 96. Published online 2012 Nov 17. doi: 10.1186/1423-0127-19-96

PMCID:: PMC3533910

Abstract Article PDF–1.7M

Select item 31780596.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 29542857.

Activation of ASK1, downstream MAPKK and MAPK isoforms during cardiac ischaemia

Stephen J. Harding, Gareth J. Browne, Bryan W. Miller, Sally A. Prigent, Martin Dickens

Biochim Biophys Acta. 2010 Sep; 1802(9): 733–740. doi: 10.1016/j.bbadis.2010.06.005

PMCID:: PMC2954285

Abstract Article

Select item 11699818.

Activation of the novel stress-activated protein kinase SAPK4 by cytokines and cellular stresses is mediated by SKK3 (MKK6); comparison of its substrate specificity with that of other SAP kinases.

M Goedert, A Cuenda, M Craxton, R Jakes, P Cohen

EMBO J. 1997 Jun 15; 16(12): 3563–3571. doi: 10.1093/emboj/16.12.3563

PMCID:: PMC1169981

Summary PDF–750K

Select item 10616519.

Role of the JIP4 Scaffold Protein in the Regulation of Mitogen-Activated Protein Kinase Signaling Pathways

Nyaya Kelkar, Claire L. Standen, Roger J. Davis

Mol Cell Biol. 2005 Apr; 25(7): 2733–2743. doi: 10.1128/MCB.25.7.2733-2743.2005

PMCID:: PMC1061651

Abstract Article PDF–890K

Select item 33828110.

Suppression of mitochondrial respiration through recruitment of p160 myb binding protein to PGC-1α: modulation by p38 MAPK

Melina Fan, James Rhee, Julie St-Pierre, Christoph Handschin, Pere Puigserver, Jiandie Lin, Sibylle Jäeger, Hediye Erdjument-Bromage, Paul Tempst, Bruce M. Spiegelman

Genes Dev. 2004 Feb 1; 18(3): 278–289. doi: 10.1101/gad.1152204

PMCID:: PMC338281

Abstract Article PDF–428K

Select item 15504611.

Targeted inhibition of p38 MAPK promotes hypertrophic cardiomyopathy through upregulation of calcineurin-NFAT signaling

Julian C. Braz, Orlando F. Bueno, Qiangrong Liang, Benjamin J. Wilkins, Yan-Shan Dai, Stephanie Parsons, Joseph Braunwart, Betty J. Glascock, Raisa Klevitsky, Thomas F. Kimball, Timothy E. Hewett, Jeffery D. Molkentin

J Clin Invest. 2003 May 15; 111(10): 1475–1486. doi: 10.1172/JCI17295

PMCID:: PMC155046

Abstract Article PDF–3.2M

Select item 13924112.

Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences

Mammalian Gene Collection (MGC) Program Team

Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26): 16899–16903. Published online 2002 Dec 11. doi: 10.1073/pnas.242603899

PMCID:: PMC139241

Abstract Article PDF–118K

Select item 12943613.

STAT4 serine phosphorylation is critical for IL-12-induced IFN-γ production but not for cell proliferation

Akio Morinobu, Massimo Gadina, Warren Strober, Roberta Visconti, Albert Fornace, Cristina Montagna, Gerald M. Feldman, Ryuta Nishikomori, John J. O'Shea

Proc Natl Acad Sci U S A. 2002 Sep 17; 99(19): 12281–12286. Published online 2002 Sep 4. doi: 10.1073/pnas.182618999

PMCID:: PMC129436

Abstract Article PDF–245K

Select item 5980614.

The in vivo role of p38 MAP kinases in cardiac remodeling and restrictive cardiomyopathy

Pu Liao, Dimitrios Georgakopoulos, Attila Kovacs, Meizi Zheng, Deborah Lerner, Haiying Pu, Jeffrey Saffitz, Kenneth Chien, Rui-Ping Xiao, David A. Kass, Yibin Wang

Proc Natl Acad Sci U S A. 2001 Oct 9; 98(21): 12283–12288. Published online 2001 Oct 2. doi: 10.1073/pnas.211086598