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Select item 111594121.

Fibroblast growth factor receptor 1 oncogene partner as a novel prognostic biomarker and therapeutic target for lung cancer

Yuria Mano, Koji Takahashi, Nobuhisa Ishikawa, Atsushi Takano, Wataru Yasui, Kouki Inai, Hitoshi Nishimura, Eiju Tsuchiya, Yusuke Nakamura, Yataro Daigo

Cancer Sci. 2007 Dec; 98(12): 1902–1913. Published online 2007 Sep 20. doi: 10.1111/j.1349-7006.2007.00610.x

PMCID:: PMC11159412

Abstract Article PDF–688K

Select item 82651732.

c-Abl promotes osteoblast expansion by differentially regulating canonical and non-canonical BMP pathways and p16^INK4a expression

Hui-Yi Kua, Huijuan Liu, Wai Fook Leong, Lili Li, Deyong Jia, Gang Ma, Yuanyu Hu, Xueying Wang, Jenny F. L. Chau, Ye-Guang Chen, Yuji Mishina, Sharon Boast, James Yeh, Li Xia, Guo-Qiang Chen, Lin He, Stephen P. Goff, Baojie Li

Nat Cell Biol. Author manuscript; available in PMC 2021 Jul 8.

Published in final edited form as: Nat Cell Biol. 2012 Jun 24; 14(7): 727–737. Published online 2012 Jun 24. doi: 10.1038/ncb2528

PMCID:: PMC8265173

Abstract Article PDF–2.1M

Select item 74336593.

C1222C Deletion in Exon 8 of ABL1 Is Involved in Carcinogenesis and Cell Cycle Control of Colorectal Cancer Through IRS1/PI3K/Akt Pathway

Yi Liu, Jian Cao, Ya-Ning Zhu, Yu Ma, Ghulam Murtaza, Yu Li, Jian-Hua Wang, Yan-Song Pu

Front Oncol. 2020; 10: 1385. Published online 2020 Aug 11. doi: 10.3389/fonc.2020.01385

PMCID:: PMC7433659

Abstract Article PDF–1.2M

Select item 73871914.

ABL1, Overexpressed in Hepatocellular Carcinomas, Regulates Expression of NOTCH1 and Promotes Development of Liver Tumors in Mice

Fang Wang, Wei Hou, Lennox Chitsike, Yingchen Xu, Carlee Bettler, Aldeb Perera, Thomas Bank, Scott J. Cotler, Asha Dhanarajan, Mitchell F. Denning, Xianzhong Ding, Peter Breslin, Wenan Qiang, Jun Li, Anthony J. Koleske, Wei Qiu

Gastroenterology. Author manuscript; available in PMC 2021 Jul 1.

Published in final edited form as: Gastroenterology. 2020 Jul; 159(1): 289–305.e16. Published online 2020 Jun 24. doi: 10.1053/j.gastro.2020.03.013

PMCID:: PMC7387191

Abstract Article PDF–2.9M

Select item 72783175.

c-Abl-p38α signaling pathway mediates dopamine neuron loss in trigeminal neuralgia

Jia Fu, Guo Mu, Ling Qiu, Jiaomei Zhao, Cehua Ou

Mol Pain. 2020; 16: 1744806920930855. Published online 2020 Jun 4. doi: 10.1177/1744806920930855

PMCID:: PMC7278317

Abstract Article PDF–1.9M

Select item 67299136.

Abl Tyrosine Kinase Promotes Dendrogenesis by Inducing Actin Cytoskeletal Rearrangements in Cooperation with Rho Family Small GTPases in Hippocampal Neurons

Shiloh B. Jones, Hope Y. Lu, Qun Lu

J Neurosci. 2004 Sep 29; 24(39): 8510–8521. doi: 10.1523/JNEUROSCI.1264-04.2004

PMCID:: PMC6729913

Abstract Article PDF–914K

Select item 66646907.

Reactive Oxygen Species Are Involved in the Development of Gastric Cancer and Gastric Cancer-Related Depression through ABL1-Mediated Inflammation Signaling Pathway

Tianhe Huang, Fuling Zhou, Xiaohan Yuan, Tian Yang, Xuan Liang, Yu Wang, Honglei Tu, Jiantong Chang, Kejun Nan, Yongchang Wei

Oxid Med Cell Longev. 2019; 2019: 5813985. Published online 2019 Jul 15. doi: 10.1155/2019/5813985

PMCID:: PMC6664690

Abstract Article PDF–3.6M

Select item 66231458.

The c-Abl-MST1 Signaling Pathway Mediates Oxidative Stress-Induced Neuronal Cell Death

Lei Xiao, Dongmei Chen, Peng Hu, Junbing Wu, Weizhe Liu, Yanhong Zhao, Mou Cao, Yuan Fang, Wenzhi Bi, Zheng Zheng, Jian Ren, Guangju Ji, Yan Wang, Zengqiang Yuan

J Neurosci. 2011 Jun 29; 31(26): 9611–9619. doi: 10.1523/JNEUROSCI.0035-11.2011

Correction in:: J Neurosci. 2021 Feb 10; 41(6): 1364.

PMCID:: PMC6623145

Abstract Article PDF–2.4M

Select item 54305429.

Differential regulation of PKD isoforms in oxidative stress conditions through phosphorylation of a conserved Tyr in the P+1 loop

Mathias Cobbaut, Rita Derua, Heike Döppler, Hua Jane Lou, Sandy Vandoninck, Peter Storz, Benjamin E. Turk, Thomas Seufferlein, Etienne Waelkens, Veerle Janssens, Johan Van Lint

Sci Rep. 2017; 7: 887. Published online 2017 Apr 20. doi: 10.1038/s41598-017-00800-w

PMCID:: PMC5430542

Abstract Article PDF–5.0M

Select item 537398710.

Germline mutations in ABL1 cause an autosomal dominant syndrome characterized by congenital heart defects and skeletal malformations

Xia Wang, Wu-Lin Charng, Chun-An Chen, Jill A. Rosenfeld, Aisha Al Shamsi, Lihadh Al-Gazali, Marianne McGuire, Nicholas Ah Mew, Georgianne L. Arnold, Chunjing Qu, Yan Ding, Donna M. Muzny, Richard A. Gibbs, Christine M. Eng, Magdalena Walkiewicz, Fan Xia, Sharon E. Plon, James R. Lupski, Christian P. Schaaf, Yaping Yang

Nat Genet. Author manuscript; available in PMC 2017 Sep 13.

Published in final edited form as: Nat Genet. 2017 Apr; 49(4): 613–617. Published online 2017 Mar 13. doi: 10.1038/ng.3815

PMCID:: PMC5373987

Abstract Article PDF–1.4M

Select item 497435811.

The Endocytic Fate of the Transferrin Receptor Is Regulated by c-Abl Kinase

Hong Cao, Barbara Schroeder, Jing Chen, Micah B. Schott, Mark A. McNiven

J Biol Chem. 2016 Aug 5; 291(32): 16424–16437. Published online 2016 May 24. doi: 10.1074/jbc.M116.724997

PMCID:: PMC4974358

Abstract Article PDF–5.0M

Select item 473483612.

Somatically mutated ABL1 is an actionable and essential NSCLC survival gene

Ewelina Testoni, Natalie L Stephenson, Pedro Torres‐Ayuso, Anna A Marusiak, Eleanor W Trotter, Andrew Hudson, Cassandra L Hodgkinson, Christopher J Morrow, Caroline Dive, John Brognard

EMBO Mol Med. 2016 Feb; 8(2): 105–116. Published online 2016 Jan 12. doi: 10.15252/emmm.201505456

PMCID:: PMC4734836

Abstract Article PDF–1.4M

Select item 452826313.

NRP1 Regulates CDC42 Activation to Promote Filopodia Formation in Endothelial Tip Cells

Alessandro Fantin, Anastasia Lampropoulou, Gaia Gestri, Claudio Raimondi, Valentina Senatore, Ian Zachary, Christiana Ruhrberg

Cell Rep. 2015 Jun 16; 11(10): 1577–1590. Published online 2015 Jun 4. doi: 10.1016/j.celrep.2015.05.018

PMCID:: PMC4528263

Abstract Article PDF–5.3M

Select item 416249714.

Outcomes of Children With BCR-ABL1–Like Acute Lymphoblastic Leukemia Treated With Risk-Directed Therapy Based on the Levels of Minimal Residual Disease

Kathryn G. Roberts, Deqing Pei, Dario Campana, Debbie Payne-Turner, Yongjin Li, Cheng Cheng, John T. Sandlund, Sima Jeha, John Easton, Jared Becksfort, Jinghui Zhang, Elaine Coustan-Smith, Susana C. Raimondi, Wing H. Leung, Mary V. Relling, William E. Evans, James R. Downing, Charles G. Mullighan, Ching-Hon Pui

J Clin Oncol. 2014 Sep 20; 32(27): 3012–3020. Published online 2014 Jul 21. doi: 10.1200/JCO.2014.55.4105

PMCID:: PMC4162497

Abstract Article PDF–236K

Select item 413683715.

Transferred BCR/ABL DNA from K562 Extracellular Vesicles Causes Chronic Myeloid Leukemia in Immunodeficient Mice

Jin Cai, Gengze Wu, Xiaorong Tan, Yu Han, Caiyu Chen, Chuanwei Li, Na Wang, Xue Zou, Xinjian Chen, Faying Zhou, Duofen He, Lin Zhou, Pedro A. Jose, Chunyu Zeng

PLoS One. 2014; 9(8): e105200. Published online 2014 Aug 18. doi: 10.1371/journal.pone.0105200

PMCID:: PMC4136837

Abstract Article PDF–3.0M

Select item 405487016.

Abelson Phosphorylation of CLASP2 Modulates its Association With Microtubules and Actin

Ulrike Engel, Yougen Zhan, Jennifer B Long, Scott N Boyle, Bryan A Ballif, Karel Dorey, Steven P Gygi, Anthony J Koleske, David VanVactor

Cytoskeleton (Hoboken) 2014 Mar; 71(3): 195–209. Published online 2014 Mar 12. doi: 10.1002/cm.21164

PMCID:: PMC4054870

Abstract Article PDF–850K

Select item 404264517.

Imatinib inhibits VEGF-independent angiogenesis by targeting neuropilin 1–dependent ABL1 activation in endothelial cells

Claudio Raimondi, Alessandro Fantin, Anastasia Lampropoulou, Laura Denti, Anissa Chikh, Christiana Ruhrberg

J Exp Med. 2014 Jun 2; 211(6): 1167–1183. doi: 10.1084/jem.20132330

PMCID:: PMC4042645

Abstract Article PDF–5.2M

Select item 402288318.

The Association of Cortactin with Profilin-1 Is Critical for Smooth Muscle Contraction

Ruping Wang, Rachel A. Cleary, Tao Wang, Jia Li, Dale D. Tang

J Biol Chem. 2014 May 16; 289(20): 14157–14169. Published online 2014 Apr 3. doi: 10.1074/jbc.M114.548099

PMCID:: PMC4022883

Abstract Article PDF–1.9M

Select item 401418919.

c-Abl phosphorylates α-synuclein and regulates its degradation: implication for α-synuclein clearance and contribution to the pathogenesis of Parkinson's disease

Anne-Laure Mahul-Mellier, Bruno Fauvet, Amanda Gysbers, Igor Dikiy, Abid Oueslati, Sandrine Georgeon, Allan J. Lamontanara, Alejandro Bisquertt, David Eliezer, Eliezer Masliah, Glenda Halliday, Oliver Hantschel, Hilal A. Lashuel

Hum Mol Genet. 2014 Jun 1; 23(11): 2858–2879. Published online 2014 Jan 9. doi: 10.1093/hmg/ddt674

PMCID:: PMC4014189

Abstract Article PDF–2.4M

Select item 396238720.

EphA4 Activation of c-Abl Mediates Synaptic Loss and LTP Blockade Caused by Amyloid-β Oligomers

Lina M. Vargas, Nancy Leal, Lisbell D. Estrada, Adrian González, Felipe Serrano, Katherine Araya, Katia Gysling, Nibaldo C. Inestrosa, Elena B. Pasquale, Alejandra R. Alvarez

PLoS One. 2014; 9(3): e92309. Published online 2014 Mar 21. doi: 10.1371/journal.pone.0092309

PMCID:: PMC3962387

Abstract Article PDF–2.5M

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