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Select item 110830941.

The Suppression of Ubiquitin C-Terminal Hydrolase L1 Promotes the Transdifferentiation of Auditory Supporting Cells into Hair Cells by Regulating the mTOR Pathway

Yeon Ju Kim, In Hye Jeong, Jung Ho Ha, Young Sun Kim, Siung Sung, Jeong Hun Jang, Yun-Hoon Choung

Cells. 2024 May; 13(9): 737. Published online 2024 Apr 24. doi: 10.3390/cells13090737

PMCID:: PMC11083094

Abstract Article PDF–12M

Select item 110731522.

Podocyte-specific deletion of ubiquitin carboxyl-terminal hydrolase L1 causes podocyte injury by inducing endoplasmic reticulum stress

Yuan Hu, Chenyang Qi, Jiaoyu Shi, Weiqiang Tan, Adiljan·Abdurusul, Zhonghua Zhao, Yanyong Xu, Huijuan Wu, Zhigang Zhang

Cell Mol Life Sci. 2023 Apr; 80(4): 106. Published online 2023 Mar 23. doi: 10.1007/s00018-023-04747-2

PMCID:: PMC11073152

Abstract Article PDF–8.2M

Select item 82123823.

Long-term inhibition of UCHL1 decreases hypertension and retinopathy in spontaneously hypertensive rats

Shasha Liu, Chengfang Wang, Jianmin Lu, Guangzheng Dai, Huixin Che, Wei He

J Int Med Res. 2021 Jun; 49(6): 03000605211020641. Published online 2021 Jun 15. doi: 10.1177/03000605211020641

PMCID:: PMC8212382

Abstract Article PDF–1.0M

Select item 67629804.

Caspase 3 Deficiency Rescues Peripheral Nervous System Defect in Retinoblastoma Nullizygous Mice

Matthew T. W. Simpson, Jason G. MacLaurin, Daigen Xu, Kerry L. Ferguson, Jacqueline L. Vanderluit, Maria A. Davoli, Sophie Roy, Donald W. Nicholson, George S. Robertson, David S. Park, Ruth S. Slack

J Neurosci. 2001 Sep 15; 21(18): 7089–7098. doi: 10.1523/JNEUROSCI.21-18-07089.2001

PMCID:: PMC6762980

Abstract Article PDF–1.2M

Select item 67626535.

P2X₃ Knock-Out Mice Reveal a Major Sensory Role for Urothelially Released ATP

Mila Vlaskovska, Lubomir Kasakov, Weifang Rong, Philippe Bodin, Michelle Bardini, Debra A. Cockayne, Anthony P. D. W. Ford, Geoffrey Burnstock

J Neurosci. 2001 Aug 1; 21(15): 5670–5677. doi: 10.1523/JNEUROSCI.21-15-05670.2001

PMCID:: PMC6762653

Abstract Article PDF–754K

Select item 67575566.

A Role of the Ubiquitin–Proteasome System in Neuropathic Pain

Andrew Moss, Gordon Blackburn-Munro, Emer M. Garry, James A. Blakemore, Tracey Dickinson, Roberta Rosie, Rory Mitchell, Susan M. Fleetwood-Walker

J Neurosci. 2002 Feb 15; 22(4): 1363–1372. doi: 10.1523/JNEUROSCI.22-04-01363.2002

PMCID:: PMC6757556

Abstract Article PDF–305K

Select item 65965007.

Ubiquitin C-Terminal Hydrolase L1 (UCH-L1) Promotes Hippocampus-Dependent Memory via Its Deubiquitinating Effect on TrkB

Yun-Yun Guo, Yi Lu, Yuan Zheng, Xiao-Rong Chen, Jun-Lu Dong, Rong-Rong Yuan, Shu-Hong Huang, Hui Yu, Yue Wang, Zhe-Yu Chen, Bo Su

J Neurosci. 2017 Jun 21; 37(25): 5978–5995. doi: 10.1523/JNEUROSCI.3148-16.2017

PMCID:: PMC6596500

Abstract Article PDF–1.9M

Select item 42768778.

The Ubiquitin C-Terminal Hydrolase L1 (UCH-L1) C Terminus Plays a Key Role in Protein Stability, but Its Farnesylation Is Not Required for Membrane Association in Primary Neurons

Paul Bishop, Philip Rubin, Andrew R. Thomson, Dan Rocca, Jeremy M. Henley

J Biol Chem. 2014 Dec 26; 289(52): 36140–36149. Published online 2014 Oct 17. doi: 10.1074/jbc.M114.557124

PMCID:: PMC4276877

Abstract Article PDF–2.0M

Select item 39962269.

In Vivo Regulation of NGF-Mediated Functions by Nedd4-2 Ubiquitination of TrkA

Tao Yu, Laura Calvo, Begoña Anta, Saray López-Benito, Roger López-Bellido, Cristina Vicente-García, Lino Tessarollo, Raquel E. Rodriguez, Juan C. Arévalo

J Neurosci. 2014 Apr 23; 34(17): 6098–6106. doi: 10.1523/JNEUROSCI.4271-13.2014

PMCID:: PMC3996226

Abstract Article PDF–1.9M

Select item 395374710.

Interactome analysis of AMP-activated protein kinase (AMPK)-α1 and -β1 in INS-1 pancreatic beta-cells by affinity purification-mass spectrometry

Sungyoon Moon, Dohyun Han, Yikwon Kim, Jonghwa Jin, Won-Kyung Ho, Youngsoo Kim

Sci Rep. 2014; 4: 4376. Published online 2014 Mar 14. doi: 10.1038/srep04376

PMCID:: PMC3953747

Abstract Article PDF–1.4M

Select item 385093911.

The proteases HtrA2/Omi and UCH-L1 regulate TNF-induced necroptosis

Justyna Sosna, Susann Voigt, Sabine Mathieu, Dieter Kabelitz, Ahmad Trad, Ottmar Janssen, Catherine Meyer-Schwesinger, Stefan Schütze, Dieter Adam

Cell Commun Signal. 2013; 11: 76. Published online 2013 Oct 3. doi: 10.1186/1478-811X-11-76

PMCID:: PMC3850939

Abstract Article PDF–1.9M

Select item 367562612.

β-Amyloid (Aβ) Oligomers Impair Brain-derived Neurotrophic Factor Retrograde Trafficking by Down-regulating Ubiquitin C-terminal Hydrolase, UCH-L1

Wayne W. Poon, Anthony J. Carlos, Brittany L. Aguilar, Nicole C. Berchtold, Crystal K. Kawano, Vahe Zograbyan, Tim Yaopruke, Michael Shelanski, Carl W. Cotman

J Biol Chem. 2013 Jun 7; 288(23): 16937–16948. Published online 2013 Apr 18. doi: 10.1074/jbc.M113.463711

PMCID:: PMC3675626

Abstract Article PDF–2.4M

Select item 352408713.

Ascl1 (Mash1) Knockout Perturbs Differentiation of Nonneuronal Cells in Olfactory Epithelium

Richard C. Krolewski, Adam Packard, Woochan Jang, Hendrik Wildner, James E. Schwob

PLoS One. 2012; 7(12): e51737. Published online 2012 Dec 17. doi: 10.1371/journal.pone.0051737

PMCID:: PMC3524087

Abstract Article PDF–10M

Select item 344340914.

Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis

Chan-Hyun Na, Drew R. Jones, Yanling Yang, Xusheng Wang, Yanji Xu, Junmin Peng

J Proteome Res. Author manuscript; available in PMC 2013 Sep 7.

Published in final edited form as: J Proteome Res. 2012 Sep 7; 11(9): 4722–4732. Published online 2012 Aug 15. doi: 10.1021/pr300536k

PMCID:: PMC3443409

Abstract Article PDF–4.2M

Select item 317805915.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 311131116.

Cholinergic chemosensory cells in the trachea regulate breathing

Gabriela Krasteva, Brendan J. Canning, Petra Hartmann, Tibor Z. Veres, Tamara Papadakis, Christian Mühlfeld, Kirstin Schliecker, Yvonne N. Tallini, Armin Braun, Holger Hackstein, Nelli Baal, Eberhard Weihe, Burkhard Schütz, Michael Kotlikoff, Ines Ibanez-Tallon, Wolfgang Kummer

Proc Natl Acad Sci U S A. 2011 Jun 7; 108(23): 9478–9483. Published online 2011 May 23. doi: 10.1073/pnas.1019418108

PMCID:: PMC3111311

Abstract Article PDF–998K

Select item 301443617.

Modification of ubiquitin-C-terminal hydrolase-L1 by cyclopentenone prostaglandins exacerbates hypoxic injury

Hao Liu, Wenjin Li, Muzamil Ahmad, Tricia M. Miller, Marie E. Rose, Samuel M. Poloyac, Guy Uechi, Manimalha Balasubramani, Robert W. Hickey, Steven H. Graham

Neurobiol Dis. Author manuscript; available in PMC 2012 Feb 1.

Published in final edited form as: Neurobiol Dis. 2011 Feb; 41(2): 318–328. Published online 2010 Oct 13. doi: 10.1016/j.nbd.2010.09.020

PMCID:: PMC3014436

Abstract Article PDF–1.9M

Select item 287241218.

Cyclopentenone prostaglandin-induced unfolding and aggregation of the Parkinson disease-associated UCH-L1

Leonardus M. I. Koharudin, Hao Liu, Roberto Di Maio, Ravindra B. Kodali, Steven H. Graham, Angela M. Gronenborn

Proc Natl Acad Sci U S A. 2010 Apr 13; 107(15): 6835–6840. Published online 2010 Mar 15. doi: 10.1073/pnas.1002295107

PMCID:: PMC2872412

Abstract Article PDF–5.4M

Select item 267610119.

Proteolipid Protein Is Required for Transport of Sirtuin 2 into CNS Myelin

Hauke B. Werner, Katja Kuhlmann, Siming Shen, Marina Uecker, Anke Schardt, Kalina Dimova, Foteini Orfaniotou, Ajit Dhaunchak, Bastian G. Brinkmann, Wiebke Möbius, Lenny Guarente, Patrizia Casaccia-Bonnefil, Olaf Jahn, Klaus-Armin Nave

J Neurosci. 2007 Jul 18; 27(29): 7717–7730. doi: 10.1523/JNEUROSCI.1254-07.2007