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Items: 1 to 20 of 31

1.
miR-432-5p Inhibits the Ferroptosis in Cardiomyocytes Induced by Hypoxia/Reoxygenation via Activating Nrf2/SLC7A11 Axis by Degrading Keap1
Wei Geng, Shaohua Yan, Xinyue Li, Qiumei Liu, Xuefei Zhang, Xinshun Gu, Xiang Tian, Yunfa Jiang
Anal Cell Pathol (Amst) 2023; 2023: 1293200. Published online 2023 Oct 3. doi: 10.1155/2023/1293200
PMCID:
PMC10564581
AbstractArticlePDF–2.7M
2.
Inhibition of MAGL activates the Keap1/Nrf2 pathway to attenuate glucocorticoid‐induced osteonecrosis of the femoral head
Ning Yang, Houyi Sun, Yi Xue, Weicheng Zhang, Hongzhi Wang, Huaqiang Tao, Xiaolong Liang, Meng Li, Yaozeng Xu, Liang Chen, Liang Zhang, Lixin Huang, Dechun Geng
Clin Transl Med. 2021 Jun; 11(6): e447. Published online 2021 Jun 1. doi: 10.1002/ctm2.447
PMCID:
PMC8167863
AbstractArticlePDF–6.3M
3.
Fucoxanthin Prevents 6-OHDA-Induced Neurotoxicity by Targeting Keap1
Wei Wu, Hui Han, Jingwangwei Liu, Min Tang, Xiaoyu Wu, Xiaojun Cao, Tiantian Zhao, Yujia Lu, Tingting Niu, Juanjuan Chen, Haimin Chen
Oxid Med Cell Longev. 2021; 2021: 6688708. Published online 2021 Mar 11. doi: 10.1155/2021/6688708
PMCID:
PMC7972864
AbstractArticlePDF–2.0M
4.
Mechanism of oxidative stress and Keap-1/Nrf2 signaling pathway in bronchopulmonary dysplasia
Di Ma, Wenhui Gao, Junjiao Liu, Dan Kong, Yunfeng Zhang, Min Qian
Medicine (Baltimore) 2020 Jun 26; 99(26): e20433. Published online 2020 Jun 26. doi: 10.1097/MD.0000000000020433
PMCID:
PMC7328910
AbstractArticlePDF–632K
5.
Berberine ameliorates CCl4-induced liver injury in rats through regulation of the Nrf2-Keap1-ARE and p53 signaling pathways
Chun-Yang Han, Tao-Tao Sun, Guang-Pei Xv, Si-Si Wang, Jin-Gang Gu, Cui-Yan Liu
Mol Med Rep. 2019 Oct; 20(4): 3095–3102. Published online 2019 Aug 6. doi: 10.3892/mmr.2019.10551
PMCID:
PMC6755230
AbstractArticlePDF–665K
6.
Hypothermic machine perfusion attenuates ischemia/reperfusion injury against rat livers donated after cardiac death by activating the Keap1/Nrf2-ARE signaling pathway
Shuai Xue, Weiyang He, Xianpeng Zeng, Zimei Tang, Shoucheng Feng, Zibiao Zhong, Yan Xiong, Yanfeng Wang, Qifa Ye
Mol Med Rep. 2018 Jul; 18(1): 815–826. Published online 2018 May 23. doi: 10.3892/mmr.2018.9065
PMCID:
PMC6059711
AbstractArticlePDF–2.2M
7.
The complexity of the Nrf2 pathway: Beyond the antioxidant response
Ying Huang, Wenji Li, Zheng-yuan Su, Ah-Ng Tony Kong
J Nutr Biochem. Author manuscript; available in PMC 2016 Dec 1.
Published in final edited form as: J Nutr Biochem. 2015 Dec; 26(12): 1401–1413. Published online 2015 Aug 8. doi: 10.1016/j.jnutbio.2015.08.001
PMCID:
PMC4785809
AbstractArticlePDF–817K
8.
Epigenetic Modifications of Keap1 Regulate Its Interaction With the Protective Factor Nrf2 in the Development of Diabetic Retinopathy
Manish Mishra, Qing Zhong, Renu A. Kowluru
Invest Ophthalmol Vis Sci. 2014 Nov; 55(11): 7256–7265. Published online 2014 Nov 13. doi: 10.1167/iovs.14-15193
PMCID:
PMC4231994
AbstractArticlePDF–712K
9.
Garlic Attenuates Cardiac Oxidative Stress via Activation of PI3K/AKT/Nrf2-Keap1 Pathway in Fructose-Fed Diabetic Rat
Raju Padiya, Debabrata Chowdhury, Roshan Borkar, R. Srinivas, Manika Pal Bhadra, Sanjay K. Banerjee
PLoS One. 2014; 9(5): e94228. Published online 2014 May 5. doi: 10.1371/journal.pone.0094228
PMCID:
PMC4010400
AbstractArticlePDF–794K
10.
Dissection of the Mammalian Midbody Proteome Reveals Conserved Cytokinesis Mechanisms
Ahna R. Skop, Hongbin Liu, John Yates, III, Barbara J. Meyer, Rebecca Heald
Science. Author manuscript; available in PMC 2013 Jun 12.
Published in final edited form as: Science. 2004 Jul 2; 305(5680): 61–66. Published online 2004 May 27. doi: 10.1126/science.1097931
PMCID:
PMC3679889
AbstractArticlePDF–1.5M
11.
Transcription Factor Nrf2-Mediated Antioxidant Defense System in the Development of Diabetic Retinopathy
Qing Zhong, Manish Mishra, Renu A. Kowluru
Invest Ophthalmol Vis Sci. 2013 Jun; 54(6): 3941–3948. Published online 2013 Jun 6. doi: 10.1167/iovs.13-11598
PMCID:
PMC3676188
AbstractArticlePDF–499K
12.
Thyroid Hormone-Induced Cytosol-to-Nuclear Translocation of Rat Liver Nrf2 Is Dependent on Kupffer Cell Functioning
Luis A. Videla, Pamela Cornejo, Pamela Romanque, Catherine Santibáñez, Iván Castillo, Romina Vargas
ScientificWorldJournal. 2012; 2012: 301494. Published online 2011 Dec 20. doi: 10.1100/2012/301494
PMCID:
PMC3353293
AbstractArticlePDF–1.1M
13.
Enhancing Nrf2 Pathway by Disruption of Keap1 in Myeloid Leukocytes Protects against Sepsis
Xiaoni Kong, Rajesh Thimmulappa, Florin Craciun, Christopher Harvey, Anju Singh, Ponvijay Kombairaju, Sekhar P. Reddy, Daniel Remick, Shyam Biswal
Am J Respir Crit Care Med. 2011 Oct 15; 184(8): 928–938. Published online 2011 Oct 15. doi: 10.1164/rccm.201102-0271OC
PMCID:
PMC3208662
AbstractArticlePDF–2.2M
14.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
15.
The Nrf2–Keap1 cellular defense pathway and heat shock protein 70 (Hsp70) response. Role in protection against oxidative stress in early neonatal unilateral ureteral obstruction (UUO)
Martin E. Rinaldi Tosi, Victoria Bocanegra, Walter Manucha, Andrea Gil Lorenzo, Patricia G. Vallés
Cell Stress Chaperones. 2011 Jan; 16(1): 57–68. Published online 2010 Aug 24. doi: 10.1007/s12192-010-0221-y
PMCID:
PMC3024087
AbstractArticlePDF–628K
16.
p62/SQSTM1 Is a Target Gene for Transcription Factor NRF2 and Creates a Positive Feedback Loop by Inducing Antioxidant Response Element-driven Gene Transcription
Ashish Jain, Trond Lamark, Eva Sjøttem, Kenneth Bowitz Larsen, Jane Atesoh Awuh, Aud Øvervatn, Michael McMahon, John D. Hayes, Terje Johansen
J Biol Chem. 2010 Jul 16; 285(29): 22576–22591. Published online 2010 May 7. doi: 10.1074/jbc.M110.118976
PMCID:
PMC2903417
AbstractArticlePDF–6.5M
17.
A Noncanonical Mechanism of Nrf2 Activation by Autophagy Deficiency: Direct Interaction between Keap1 and p62
Alexandria Lau, Xiao-Jun Wang, Fei Zhao, Nicole F. Villeneuve, Tongde Wu, Tao Jiang, Zheng Sun, Eileen White, Donna D. Zhang
Mol Cell Biol. 2010 Jul; 30(13): 3275–3285. Published online 2010 Apr 26. doi: 10.1128/MCB.00248-10
PMCID:
PMC2897585
AbstractArticlePDF–2.9M
18.
Deletion of Keap1 in the Lung Attenuates Acute Cigarette Smoke–Induced Oxidative Stress and Inflammation
David J. Blake, Anju Singh, Ponvijay Kombairaju, Deepti Malhotra, Thomas J. Mariani, Rubin M. Tuder, Edward Gabrielson, Shyam Biswal
Am J Respir Cell Mol Biol. 2010 May; 42(5): 524–536. Published online 2009 Jun 11. doi: 10.1165/rcmb.2009-0054OC
PMCID:
PMC2874439
AbstractArticlePDF–821K
19.
Keap1 is a forked-stem dimer structure with two large spheres enclosing the intervening, double glycine repeat, and C-terminal domains
Toshihiko Ogura, Kit I. Tong, Kazuhiro Mio, Yuusuke Maruyama, Hirofumi Kurokawa, Chikara Sato, Masayuki Yamamoto
Proc Natl Acad Sci U S A. 2010 Feb 16; 107(7): 2842–2847. Published online 2010 Jan 27. doi: 10.1073/pnas.0914036107
PMCID:
PMC2840362
AbstractArticlePDF–963K
20.
Ectodermal-Neural Cortex 1 Down-Regulates Nrf2 at the Translational Level
Xiao-Jun Wang, Donna D. Zhang
PLoS One. 2009; 4(5): e5492. Published online 2009 May 8. doi: 10.1371/journal.pone.0005492
PMCID:
PMC2675063
AbstractArticlePDF–592K

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