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Select item 93408631.

N‐Acetylcysteine protects against cobalt chloride‐induced endothelial dysfunction by enhancing glucose‐6‐phosphate dehydrogenase activity

Chen Yang, Xiaofang Zhang, Xilin Ge, Chunmei He, Suhuan Liu, Shuyu Yang, Caoxin Huang

FEBS Open Bio. 2022 Aug; 12(8): 1475–1488. Published online 2022 Jun 20. doi: 10.1002/2211-5463.13449

PMCID:: PMC9340863

Abstract Article PDF–2.2M

Select item 67426462.

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations

Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu

Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3

PMCID:: PMC6742646

Abstract Article PDF–1.2M

Select item 67410013.

Localization of a β-Actin Messenger Ribonucleoprotein Complex with Zipcode-Binding Protein Modulates the Density of Dendritic Filopodia and Filopodial Synapses

Taesun Eom, Laura N. Antar, Robert H. Singer, Gary J. Bassell

J Neurosci. 2003 Nov 12; 23(32): 10433–10444. doi: 10.1523/JNEUROSCI.23-32-10433.2003

PMCID:: PMC6741001

Abstract Article PDF–819K

Select item 66712374.

Spatial Learning Impairment, Enhanced CDK5/p35 Activity, and Downregulation of NMDA Receptor Expression in Transgenic Mice Expressing Tau-Tubulin Kinase 1

Shinji Sato, Jiqing Xu, Satoshi Okuyama, Lindsey B. Martinez, Shannon M. Walsh, Michael T. Jacobsen, Russell J. Swan, Joshua D. Schlautman, Pawel Ciborowski, Tsuneya Ikezu

J Neurosci. 2008 Dec 31; 28(53): 14511–14521. doi: 10.1523/JNEUROSCI.3417-08.2008

PMCID:: PMC6671237

Abstract Article PDF–709K

Select item 66230665.

Parkin Interacts with Ambra1 to Induce Mitophagy

Cindy Van Humbeeck, Tom Cornelissen, Hilde Hofkens, Wim Mandemakers, Kris Gevaert, Bart De Strooper, Wim Vandenberghe

J Neurosci. 2011 Jul 13; 31(28): 10249–10261. doi: 10.1523/JNEUROSCI.1917-11.2011

PMCID:: PMC6623066

Abstract Article PDF–3.5M

Select item 63149576.

An interactome perturbation framework prioritizes damaging missense mutations for developmental disorders

Siwei Chen, Robert Fragoza, Lambertus Klei, Yuan Liu, Jiebiao Wang, Kathryn Roeder, Bernie Devlin, Haiyuan Yu

Nat Genet. Author manuscript; available in PMC 2019 Jul 1.

Published in final edited form as: Nat Genet. 2018 Jul; 50(7): 1032–1040. Published online 2018 Jun 11. doi: 10.1038/s41588-018-0130-z

PMCID:: PMC6314957

Abstract Article PDF–1.3M

Select item 60524977.

Nonmuscle myosin II isoforms interact with sodium channel alpha subunits

Bhagirathi Dash, Chongyang Han, Stephen G Waxman, Sulayman D Dib-Hajj

Mol Pain. 2018; 14: 1744806918788638. Published online 2018 Jul 18. doi: 10.1177/1744806918788638

PMCID:: PMC6052497

Abstract Article PDF–818K

Select item 59960248.

Ependymal cilia beating induces an actin network to protect centrioles against shear stress

Alexia Mahuzier, Asm Shihavuddin, Clémence Fournier, Pauline Lansade, Marion Faucourt, Nikita Menezes, Alice Meunier, Meriem Garfa-Traoré, Marie-France Carlier, Raphael Voituriez, Auguste Genovesio, Nathalie Spassky, Nathalie Delgehyr

Nat Commun. 2018; 9: 2279. Published online 2018 Jun 11. doi: 10.1038/s41467-018-04676-w

PMCID:: PMC5996024

Abstract Article PDF–5.9M

Select item 58249589.

Identification and characterization of the BRI2 interactome in the brain

Filipa Martins, Ana M. Marafona, Cátia D. Pereira, Thorsten Müller, Christina Loosse, Katharina Kolbe, Odete A. B. da Cruz e Silva, Sandra Rebelo

Sci Rep. 2018; 8: 3548. Published online 2018 Feb 23. doi: 10.1038/s41598-018-21453-3

PMCID:: PMC5824958

Abstract Article PDF–1.7M

Select item 571138610.

Sperm Release at Spermiation Is Regulated by Changes in the Organization of Actin- and Microtubule-Based Cytoskeletons at the Apical Ectoplasmic Specialization—A Study Using the Adjudin Model

Linxi Li, Elizabeth I. Tang, Haiqi Chen, Qingquan Lian, Renshan Ge, Bruno Silvestrini, C. Yan Cheng

Endocrinology. 2017 Dec 1; 158(12): 4300–4316. Published online 2017 Oct 12. doi: 10.1210/en.2017-00660

PMCID:: PMC5711386

Abstract Article

Select item 551829411.

A recurrent de novo mutation in ACTG1 causes isolated ocular coloboma

Joe Rainger, Kathleen A Williamson, Dinesh C Soares, Julia Truch, Dominic Kurian, Gabriele Gillessen‐Kaesbach, Anne Seawright, James Prendergast, Mihail Halachev, Ann Wheeler, Lynn McTeir, Andrew C Gill, Veronica van Heyningen, Megan G Davey, UK10K, David R FitzPatrick

Hum Mutat. 2017 Aug; 38(8): 942–946. Published online 2017 Jun 6. doi: 10.1002/humu.23246

PMCID:: PMC5518294

Abstract Article PDF–1.1M

Select item 533657712.

Type of supplemented simple sugar, not merely calorie intake, determines adverse effects on metabolism and aortic function in female rats

Gemma Sangüesa, Sonali Shaligram, Farjana Akther, Núria Roglans, Juan C. Laguna, Roshanak Rahimian, Marta Alegret

Am J Physiol Heart Circ Physiol. 2017 Feb 1; 312(2): H289–H304. Published online 2016 Dec 6. doi: 10.1152/ajpheart.00339.2016

PMCID:: PMC5336577

Abstract Article

Select item 514573413.

Actin is crucial for all kinetically distinguishable forms of endocytosis at synapses

Xin-Sheng Wu, Sunghoon Lee, Jiansong Sheng, Zhen Zhang, Weidong Zhao, Dongsheng Wang, Yinghui Jin, Patrick Charnay, James M. Ervasti, Ling-Gang Wu

Neuron. Author manuscript; available in PMC 2017 Dec 7.

Published in final edited form as: Neuron. 2016 Dec 7; 92(5): 1020–1035. Published online 2016 Nov 10. doi: 10.1016/j.neuron.2016.10.014

PMCID:: PMC5145734

Abstract Article PDF–1.9M

Select item 481673914.

Coordination of Actin- and Microtubule-Based Cytoskeletons Supports Transport of Spermatids and Residual Bodies/Phagosomes During Spermatogenesis in the Rat Testis

Elizabeth I. Tang, Will M. Lee, C. Yan Cheng

Endocrinology. 2016 Apr; 157(4): 1644–1659. Published online 2016 Feb 19. doi: 10.1210/en.2015-1962

PMCID:: PMC4816739

Abstract Article

Select item 455193215.

Different motif requirements for the localization zipcode element of β-actin mRNA binding by HuD and ZBP1

Hak Hee Kim, Seung Joon Lee, Amy S. Gardiner, Nora I. Perrone-Bizzozero, Soonmoon Yoo

Nucleic Acids Res. 2015 Sep 3; 43(15): 7432–7446. Published online 2015 Jul 7. doi: 10.1093/nar/gkv699

PMCID:: PMC4551932

Abstract Article PDF–3.8M

Select item 444121516.

Widespread Macromolecular Interaction Perturbations in Human Genetic Disorders

Nidhi Sahni, Song Yi, Mikko Taipale, Juan I. Fuxman Bass, Jasmin Coulombe-Huntington, Fan Yang, Jian Peng, Jochen Weile, Georgios I. Karras, Yang Wang, István A. Kovács, Atanas Kamburov, Irina Krykbaeva, Mandy H. Lam, George Tucker, Vikram Khurana, Amitabh Sharma, Yang-Yu Liu, Nozomu Yachie, Quan Zhong, Yun Shen, Alexandre Palagi, Adriana San-Miguel, Changyu Fan, Dawit Balcha, Amelie Dricot, Daniel M. Jordan, Jennifer M. Walsh, Akash A. Shah, Xinping Yang, Ani Stoyanova, Alex Leighton, Michael A. Calderwood, Yves Jacob, Michael E. Cusick, Kourosh Salehi-Ashtiani, Luke J. Whitesell, Shamil Sunyaev, Bonnie Berger, Albert-László Barabási, Benoit Charloteaux, David E. Hill, Tong Hao, Frederick P. Roth, Yu Xia, Albertha J.M. Walhout, Susan Lindquist, Marc Vidal

Cell. Author manuscript; available in PMC 2016 Apr 23.

Published in final edited form as: Cell. 2015 Apr 23; 161(3): 647–660. doi: 10.1016/j.cell.2015.04.013

PMCID:: PMC4441215

Abstract Article PDF–1.2M

Select item 436245617.

ZO-1 controls endothelial adherens junctions, cell–cell tension, angiogenesis, and barrier formation

Olga Tornavaca, Minghao Chia, Neil Dufton, Lourdes Osuna Almagro, Daniel E. Conway, Anna M. Randi, Martin A. Schwartz, Karl Matter, Maria S. Balda

J Cell Biol. 2015 Mar 16; 208(6): 821–838. doi: 10.1083/jcb.201404140

PMCID:: PMC4362456

Abstract Article PDF–7.4M

Select item 433545718.

γ-Actin plays a key role in endothelial cell motility and neovessel maintenance

Eddy Pasquier, Maria-Pia Tuset, Snega Sinnappan, Michael Carnell, Alexander Macmillan, Maria Kavallaris

Vasc Cell. 2015; 7: 2. Published online 2015 Feb 6. doi: 10.1186/s13221-014-0027-2

PMCID:: PMC4335457

Abstract Article PDF–3.2M

Select item 426658819.

A proteome-scale map of the human interactome network

Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal

Cell. Author manuscript; available in PMC 2015 Nov 20.

Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050

PMCID:: PMC4266588

Abstract Article PDF–3.1M

Select item 426337120.

A Massively Parallel Pipeline to Clone DNA Variants and Examine Molecular Phenotypes of Human Disease Mutations

Xiaomu Wei, Jishnu Das, Robert Fragoza, Jin Liang, Francisco M. Bastos de Oliveira, Hao Ran Lee, Xiujuan Wang, Matthew Mort, Peter D. Stenson, David N. Cooper, Steven M. Lipkin, Marcus B. Smolka, Haiyuan Yu

PLoS Genet. 2014 Dec; 10(12): e1004819. Published online 2014 Dec 11. doi: 10.1371/journal.pgen.1004819

PMCID:: PMC4263371

Abstract Article PDF–7.6M

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