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Select item 105114121.

Leptin receptor gene deficiency minimally affects osseointegration in rats

Martina Jolic, Krisztina Ruscsák, Lena Emanuelsson, Birgitta Norlindh, Peter Thomsen, Furqan A. Shah, Anders Palmquist

Sci Rep. 2023; 13: 15631. Published online 2023 Sep 20. doi: 10.1038/s41598-023-42379-5

PMCID:: PMC10511412

Abstract Article PDF–5.8M

Select item 88605432.

TNF-α Antagonizes the Effect of Leptin on Insulin Secretion through FOXO1-Dependent Transcriptional Suppression of LepRb in INS-1 Cells

Yang Zhang, Weidong Jin, Dongyun Zhang, Changhai Lin, Haiyan He, Fengxin Xie, Lixia Gan, Weiling Fu, Lixiang Wu, Yongzhong Wu

Oxid Med Cell Longev. 2022; 2022: 9142798. Published online 2022 Feb 14. doi: 10.1155/2022/9142798

PMCID:: PMC8860543

Abstract Article PDF–2.6M

Select item 76114993.

Nicotinamide for the treatment of heart failure with preserved ejection fraction

Mahmoud Abdellatif, Viktoria Trummer-Herbst, Franziska Koser, Sylvère Durand, Rui Adão, Francisco Vasques-Nóvoa, Johanna K. Freundt, Julia Voglhuber, Maria-Rosaria Pricolo, Michael Kasa, Clara Türk, Fanny Aprahamian, Elías Herrero-Galán, Sebastian J. Hofer, Tobias Pendl, Lavinia Rech, Julia Kargl, Nathaly Anto-Michel, Senka Ljubojevic-Holzer, Julia Schipke, Christina Brandenberger, Martina Auer, Renate Schreiber, Chintan N. Koyani, Akos Heinemann, Andreas Zirlik, Albrecht Schmidt, Dirk von Lewinski, Daniel Scherr, Peter P. Rainer, Julia von Maltzahn, Christian Mühlfeld, Marcus Krüger, Saša Frank, Frank Madeo, Tobias Eisenberg, Andreas Prokesch, Adelino F. Leite-Moreira, André P. Lourenço, Jorge Alegre-Cebollada, Stefan Kiechl, Wolfgang A. Linke, Guido Kroemer, Simon Sedej

Sci Transl Med. Author manuscript; available in PMC 2021 Aug 16.

Published in final edited form as: Sci Transl Med. 2021 Feb 10; 13(580): eabd7064. Published online 2021 Feb 10. doi: 10.1126/scitranslmed.abd7064

PMCID:: PMC7611499

Abstract Article PDF–3.6M

Select item 75240624.

ZSF1 rat as animal model for HFpEF: Development of reduced diastolic function and skeletal muscle dysfunction

Antje Schauer, Runa Draskowski, Anett Jannasch, Virginia Kirchhoff, Keita Goto, Anita Männel, Peggy Barthel, Antje Augstein, Ephraim Winzer, Malte Tugtekin, Siegfried Labeit, Axel Linke, Volker Adams

ESC Heart Fail. 2020 Oct; 7(5): 2123–2134. Published online 2020 Jul 25. doi: 10.1002/ehf2.12915

PMCID:: PMC7524062

Abstract Article PDF–1.6M

Select item 73117045.

Depletion of macrophages slows the early progression of renal injury in obese Dahl salt-sensitive leptin receptor mutant rats

Bibek Poudel, Corbin A. Shields, Andrea K. Brown, Ubong Ekperikpe, Tyler Johnson, Denise C. Cornelius, Jan M. Williams

Am J Physiol Renal Physiol. 2020 Jun 1; 318(6): F1489–F1499. Published online 2020 May 11. doi: 10.1152/ajprenal.00100.2020

PMCID:: PMC7311704

Abstract Article

Select item 62448936.

Leptin receptor is expressed by tissue mast cells

Paulina Żelechowska, Magdalena Wiktorska, Sylwia Różalska, Olga Stasikowska-Kanicka, Małgorzata Wągrowska-Danilewicz, Justyna Agier, Ewa Brzezińska-Błaszczyk

Immunol Res. 2018; 66(5): 557–566. Published online 2018 Sep 29. doi: 10.1007/s12026-018-9029-0

PMCID:: PMC6244893

Abstract Article PDF–3.7M

Select item 59988607.

Study of the association of 17 lipid-related gene polymorphisms with coronary heart disease

Nan Wu, Guili Liu, Yi Huang, Qi Liao, Liyuan Han, Huandan Ye, Shiwei Duan, Xiaomin Chen

Anatol J Cardiol. 2018 Jun; 19(6): 360–367. Published online 2018 May 11. doi: 10.14744/AnatolJCardiol.2018.23682

PMCID:: PMC5998860

Abstract Article PDF–136K

Select item 59286628.

Role of leptin and the leptin receptor in the pathogenesis of varicocele-induced testicular dysfunction

Jie Zhang, Peng-Peng Jin, Min Gong, Qing-Tong Yi, Ru-Jian Zhu

Mol Med Rep. 2018 May; 17(5): 7065–7072. Published online 2018 Mar 15. doi: 10.3892/mmr.2018.8753

PMCID:: PMC5928662

Abstract Article PDF–1.9M

Select item 55290269.

High resolution molecular and histological analysis of renal disease progression in ZSF1 fa/fa^CP rats, a model of type 2 diabetic nephropathy

Ken Dower, Shanrong Zhao, Franklin J. Schlerman, Leigh Savary, Gabriela Campanholle, Bryce G. Johnson, Li Xi, Vuong Nguyen, Yutian Zhan, Matthew P. Lech, Ju Wang, Qing Nie, Morten A. Karsdal, Federica Genovese, Germaine Boucher, Thomas P. Brown, Baohong Zhang, Bruce L. Homer, Robert V. Martinez

PLoS One. 2017; 12(7): e0181861. Published online 2017 Jul 26. doi: 10.1371/journal.pone.0181861

PMCID:: PMC5529026

Abstract Article PDF–24M

Select item 551663610.

Leptin receptor polymorphisms and lung function decline in COPD

N.N. Hansel, L. Gao, N.M. Rafaels, R.A. Mathias, E.R. Neptune, C. Tankersley, A.V. Grant, J. Connett, T.H. Beaty, R.A. Wise, K.C. Barnes

Eur Respir J. Author manuscript; available in PMC 2017 Jul 19.

Published in final edited form as: Eur Respir J. 2009 Jul; 34(1): 103–110. Published online 2009 Feb 5. doi: 10.1183/09031936.00120408

PMCID:: PMC5516636

Abstract Article PDF–792K

Select item 514223611.

Early development of podocyte injury independently of hyperglycemia and elevations in arterial pressure in nondiabetic obese Dahl SS leptin receptor mutant rats

Kasi C. McPherson, Lateia Taylor, Ashley C. Johnson, Sean P. Didion, Aron M. Geurts, Michael R. Garrett, Jan M. Williams

Am J Physiol Renal Physiol. 2016 Oct 1; 311(4): F793–F804. Published online 2016 Jul 27. doi: 10.1152/ajprenal.00590.2015

PMCID:: PMC5142236

Abstract Article

Select item 488849912.

Leptin Receptor Gene Polymorphisms and the Risk of Non-Alcoholic Fatty Liver Disease and Coronary Atherosclerosis in the Chinese Han Population

Bai-Quan An, Lin-Lin Lu, Chen Yuan, Yong-Ning Xin, Shi-Ying Xuan

Hepat Mon. 2016 Apr; 16(4): e35055. Published online 2016 Apr 27. doi: 10.5812/hepatmon.35055

PMCID:: PMC4888499

Abstract Article PDF–144K

Select item 466698413.

Leptin decreases heart rate associated with increased ventricular repolarization via its receptor

Yen-Chang Lin, Jianying Huang, Stan Hileman, Karen H. Martin, Robert Hull, Mary Davis, Han-Gang Yu

Am J Physiol Heart Circ Physiol. 2015 Nov 15; 309(10): H1731–H1739. Published online 2015 Sep 25. doi: 10.1152/ajpheart.00623.2015

PMCID:: PMC4666984

Abstract Article

Select item 463358214.

Preliminary Characterization of a Leptin Receptor Knockout Rat Created by CRISPR/Cas9 System

Dan Bao, Yuanwu Ma, Xu Zhang, Feifei Guan, Wei Chen, Kai Gao, Chuan Qin, Lianfeng Zhang

Sci Rep. 2015; 5: 15942. Published online 2015 Nov 5. doi: 10.1038/srep15942

PMCID:: PMC4633582

Abstract Article PDF–1.8M

Select item 425523415.

Leptin-inhibited PBN neurons enhance counter-regulatory responses to hypoglycemia in negative energy balance

Jonathan N. Flak, Christa M. Patterson, Alastair S. Garfield, Giuseppe D’Agostino, Paulette B. Goforth, Amy K. Sutton, Paige A. Malec, Jenny-Marie T. Wong, Mark Germani, Justin C. Jones, Michael Rajala, Leslie Satin, Christopher J. Rhodes, David P. Olson, Robert T. Kennedy, Lora K. Heisler, Martin G. Myers, Jr.

Nat Neurosci. Author manuscript; available in PMC 2015 Jun 1.

Published in final edited form as: Nat Neurosci. 2014 Dec; 17(12): 1744–1750. Published online 2014 Nov 10. doi: 10.1038/nn.3861