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Items: 1 to 20 of 39

1.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
2.
Dipeptidyl peptidase like 6 promoter methylation is a potential prognostic biomarker for pancreatic ductal adenocarcinoma
Xin Zhao, Di Cao, Zhangyong Ren, Zhe Liu, Shaocheng Lv, Jiqiao Zhu, Lixin Li, Ren Lang, Qiang He
Biosci Rep. 2020 Jul 31; 40(7): BSR20200214. Published online 2020 Jul 30. doi: 10.1042/BSR20200214
PMCID:
PMC7396423
AbstractArticlePDF–1.2M
3.
Loss of DPP6 in neurodegenerative dementia: a genetic player in the dysfunction of neuronal excitability
Rita Cacace, Bavo Heeman, Sara Van Mossevelde, Arne De Roeck, Julie Hoogmartens, Peter De Rijk, Helena Gossye, Kristof De Vos, Wouter De Coster, Mojca Strazisar, Greet De Baets, Joost Schymkowitz, Frederic Rousseau, Nathalie Geerts, Tim De Pooter, Karin Peeters, Anne Sieben, Jean-Jacques Martin, Sebastiaan Engelborghs, Eric Salmon, Patrick Santens, Rik Vandenberghe, Patrick Cras, Peter P. De Deyn, John C. van Swieten, Cornelia M. van Duijn, Julie van der Zee, Kristel Sleegers, Christine Van Broeckhoven, the BELNEU Consortium
Acta Neuropathol. 2019; 137(6): 901–918. Published online 2019 Mar 14. doi: 10.1007/s00401-019-01976-3
PMCID:
PMC6531610
AbstractArticlePDF–3.2M
4.
Implication of LRRC4C and DPP6 in neurodevelopmental disorders
Gilles Maussion, Cristiana Cruceanu, Jill A. Rosenfeld, Scott C. Bell, Fabrice Jollant, Jin Szatkiewicz, Ryan L. Collins, Carrie Hanscom, Ilaria Kolobova, Nicolas Menjot de Champfleur, Ian Blumenthal, Colby Chiang, Vanessa Ota, Christina Hultman, Colm O’Dushlaine, Steve McCarroll, Martin Alda, Sebastien Jacquemont, Zehra Ordulu, Christian R. Marshall, Melissa T. Carter, Lisa G. Shaffer, Pamela Sklar, Santhosh Girirajan, Cynthia C. Morton, James F. Gusella, Gustavo Turecki, D. J. Stavropoulos, Patrick F. Sullivan, Stephen W. Scherer, Michael E. Talkowski, Carl Ernst
Am J Med Genet A. Author manuscript; available in PMC 2018 Mar 2.
Published in final edited form as: Am J Med Genet A. 2017 Feb; 173(2): 395–406. Published online 2016 Oct 19. doi: 10.1002/ajmg.a.38021
PMCID:
PMC5833302
AbstractArticlePDF–734K
5.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
6.
Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing
Teng Fei, Yiwen Chen, Tengfei Xiao, Wei Li, Laura Cato, Peng Zhang, Maura B. Cotter, Michaela Bowden, Rosina T. Lis, Shuang G. Zhao, Qiu Wu, Felix Y. Feng, Massimo Loda, Housheng Hansen He, X. Shirley Liu, Myles Brown
Proc Natl Acad Sci U S A. 2017 Jun 27; 114(26): E5207–E5215. Published online 2017 Jun 13. doi: 10.1073/pnas.1617467114
PMCID:
PMC5495225
AbstractArticlePDF–1.3M
7.
The BioPlex Network: A Systematic Exploration of the Human Interactome
Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2016 Jul 16.
Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043
PMCID:
PMC4617211
AbstractArticlePDF–2.2M
8.
Unique Cardiac Purkinje Fiber Transient Outward Current β-Subunit Composition: A Potential Molecular Link to Idiopathic Ventricular Fibrillation
Ling Xiao, Tamara T. Koopmann, Balázs Ördög, Pieter G. Postema, Arie O. Verkerk, Vivek Iyer, Kevin J. Sampson, Gerard J.J. Boink, Maya A. Mamarbachi, Andras Varro, Luc Jordaens, Jan Res, Robert S. Kass, Arthur A. Wilde, C.R. Bezzina, Stanley Nattel
Circ Res. Author manuscript; available in PMC 2015 Jun 14.
Published in final edited form as: Circ Res. 2013 May 10; 112(10): 1310–1322. Published online 2013 Mar 26. doi: 10.1161/CIRCRESAHA.112.300227
PMCID:
PMC4465785
AbstractArticlePDF–4.9M
9.
DPP6 Domains Responsible for Its Localization and Function
Lin Lin, Laura K. Long, Michael M. Hatch, Dax A. Hoffman
J Biol Chem. 2014 Nov 14; 289(46): 32153–32165. Published online 2014 Sep 4. doi: 10.1074/jbc.M114.578070
PMCID:
PMC4231691
AbstractArticlePDF–3.3M
10.
Genome-Wide Diet-Gene Interaction Analyses for Risk of Colorectal Cancer
Jane C. Figueiredo, Li Hsu, Carolyn M. Hutter, Yi Lin, Peter T. Campbell, John A. Baron, Sonja I. Berndt, Shuo Jiao, Graham Casey, Barbara Fortini, Andrew T. Chan, Michelle Cotterchio, Mathieu Lemire, Steven Gallinger, Tabitha A. Harrison, Loic Le Marchand, Polly A. Newcomb, Martha L. Slattery, Bette J. Caan, Christopher S. Carlson, Brent W. Zanke, Stephanie A. Rosse, Hermann Brenner, Edward L. Giovannucci, Kana Wu, Jenny Chang-Claude, Stephen J. Chanock, Keith R. Curtis, David Duggan, Jian Gong, Robert W. Haile, Richard B. Hayes, Michael Hoffmeister, John L. Hopper, Mark A. Jenkins, Laurence N. Kolonel, Conghui Qu, Anja Rudolph, Robert E. Schoen, Fredrick R. Schumacher, Daniela Seminara, Deanna L. Stelling, Stephen N. Thibodeau, Mark Thornquist, Greg S. Warnick, Brian E. Henderson, Cornelia M. Ulrich, W. James Gauderman, John D. Potter, Emily White, Ulrike Peters, on behalf of CCFR, and GECCO
PLoS Genet. 2014 Apr; 10(4): e1004228. Published online 2014 Apr 17. doi: 10.1371/journal.pgen.1004228
PMCID:
PMC3990510
AbstractArticlePDF–878K
11.
A Genome-Wide Association Study of Clinical Symptoms of Dissociation in a Trauma-Exposed Sample
Erika J. Wolf, Ann M. Rasmusson, Karen S. Mitchell, Mark W. Logue, Clinton T. Baldwin, Mark W. Miller
Depress Anxiety. Author manuscript; available in PMC 2015 Apr 1.
Published in final edited form as: Depress Anxiety. 2014 Apr; 31(4): 352–360. Published online 2014 Mar 27. doi: 10.1002/da.22260
PMCID:
PMC3984628
AbstractArticlePDF–657K
12.
The Prion Protein Modulates A-type K+ Currents Mediated by Kv4.2 Complexes through Dipeptidyl Aminopeptidase-like Protein 6
Robert C. C. Mercer, Li Ma, Joel C. Watts, Robert Strome, Serene Wohlgemuth, Jing Yang, Neil R. Cashman, Michael B. Coulthart, Gerold Schmitt-Ulms, Jack H. Jhamandas, David Westaway
J Biol Chem. 2013 Dec 27; 288(52): 37241–37255. Published online 2013 Nov 13. doi: 10.1074/jbc.M113.488650
PMCID:
PMC3873577
AbstractArticlePDF–2.4M
13.
DPP6 regulation of dendritic morphogenesis impacts hippocampal synaptic development
Lin Lin, Wei Sun, Ben Throesch, Faith Kung, Jameice T Decoster, Cory J Berner, Richard E. Cheney, Bernardo Rudy, Dax A Hoffman
Nat Commun. Author manuscript; available in PMC 2014 Feb 5.
Published in final edited form as: Nat Commun. 2013; 4: 2270. doi: 10.1038/ncomms3270
PMCID:
PMC3775611
AbstractArticlePDF–2.5M
14.
Generalization of Variants Identified by Genome-wide Association Studies for Electrocardiographic Traits in African Americans
Janina M. Jeff, Marylyn D. Ritchie, Joshua C. Denny, Abel N. Kho, Andrea H. Ramirez, David Crosslin, Loren Armstrong, Melissa A. Basford, Wendy A. Wolf, Jennifer A. Pacheco, Rex L. Chisholm, Dan M. Roden, M. Geoffrey Hayes, Dana C. Crawford
Ann Hum Genet. Author manuscript; available in PMC 2014 Jul 30.
Published in final edited form as: Ann Hum Genet. 2013 Jul; 77(4): 321–332. Published online 2013 Mar 28. doi: 10.1111/ahg.12023
PMCID:
PMC3743946
AbstractArticlePDF–375K
15.
Functional Stoichiometry Underlying KChIP Regulation of Kv4.2 Functional Expression
Kumud Kunjilwar, Yan Qian, Paul J. Pfaffinger
J Neurochem. Author manuscript; available in PMC 2014 Aug 1.
Published in final edited form as: J Neurochem. 2013 Aug; 126(4): 462–472. Published online 2013 Jun 10. doi: 10.1111/jnc.12309
PMCID:
PMC3737270
AbstractArticlePDF–2.0M
16.
A New TASK for Dipeptidyl Peptidase-like Protein 6
Brian M. Nadin, Paul J. Pfaffinger
PLoS One. 2013; 8(4): e60831. Published online 2013 Apr 9. doi: 10.1371/journal.pone.0060831
PMCID:
PMC3621905
AbstractArticlePDF–2.5M
17.
A Novel N-terminal Motif of Dipeptidyl Peptidase-like Proteins Produces Rapid Inactivation of Kv4.2 Channels by a Pore-blocking Mechanism
Henry H. Jerng, Kevin Dougherty, Manuel Covarrubias, Paul J. Pfaffinger
Channels (Austin) Author manuscript; available in PMC 2013 Mar 25.
Published in final edited form as: Channels (Austin). 2009 Nov; 3(6): 448–461. Published online 2009 Nov 30. doi: 10.4161/chan.3.6.10216
PMCID:
PMC3607289
AbstractArticlePDF–2.7M
18.
Encephalitis and antibodies to DPPX, a subunit of Kv4.2 potassium channels
Anna Boronat, Jeffrey M. Gelfand, Nuria Gresa-Arribas, Hyo-Young Jeong, Michael Walsh, Kirk Roberts, Eugenia Martinez-Hernandez, Myrna R. Rosenfeld, Rita Balice-Gordon, Francesc Graus, Bernardo Rudy, Josep Dalmau
Ann Neurol. Author manuscript; available in PMC 2014 Jan 1.
Published in final edited form as: Ann Neurol. 2013 Jan; 73(1): 120–128. Published online 2012 Dec 7. doi: 10.1002/ana.23756
PMCID:
PMC3563722
AbstractArticlePDF–1.8M
19.
Loci Associated with N-Glycosylation of Human Immunoglobulin G Show Pleiotropy with Autoimmune Diseases and Haematological Cancers
Gordan Lauc, Jennifer E. Huffman, Maja Pučić, Lina Zgaga, Barbara Adamczyk, Ana Mužinić, Mislav Novokmet, Ozren Polašek, Olga Gornik, Jasminka Krištić, Toma Keser, Veronique Vitart, Blanca Scheijen, Hae-Won Uh, Mariam Molokhia, Alan Leslie Patrick, Paul McKeigue, Ivana Kolčić, Ivan Krešimir Lukić, Olivia Swann, Frank N. van Leeuwen, L. Renee Ruhaak, Jeanine J. Houwing-Duistermaat, P. Eline Slagboom, Marian Beekman, Anton J. M. de Craen, André M. Deelder, Qiang Zeng, Wei Wang, Nicholas D. Hastie, Ulf Gyllensten, James F. Wilson, Manfred Wuhrer, Alan F. Wright, Pauline M. Rudd, Caroline Hayward, Yurii Aulchenko, Harry Campbell, Igor Rudan
PLoS Genet. 2013 Jan; 9(1): e1003225. Published online 2013 Jan 31. doi: 10.1371/journal.pgen.1003225
PMCID:
PMC3561084
AbstractArticlePDF–1.0M
20.
A Synthetic Interaction Screen Identifies Factors Selectively Required for Proliferation and TERT Transcription in p53-Deficient Human Cancer Cells
Li Xie, Claude Gazin, Sung Mi Park, Lihua J. Zhu, Marie-anne Debily, Ellen L. W. Kittler, Maria L. Zapp, David Lapointe, Stephane Gobeil, Ching-Man Virbasius, Michael R. Green
PLoS Genet. 2012 Dec; 8(12): e1003151. Published online 2012 Dec 20. doi: 10.1371/journal.pgen.1003151
PMCID:
PMC3527276
AbstractArticlePDF–1.8M

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