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Select item 91197361.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 84501102.

Activation of bivalent factor DLX5 cooperates with master regulator TP63 to promote squamous cell carcinoma

Yongsheng Huang, Qian Yang, Yueyuan Zheng, Lehang Lin, Xin Xu, Xiu-E Xu, Tiago C Silva, Masaharu Hazawa, Li Peng, Haotian Cao, Yanbing Ding, Daning Lu, Benjamin P Berman, Li-Yan Xu, En-Min Li, Dong Yin

Nucleic Acids Res. 2021 Sep 20; 49(16): 9246–9263. Published online 2021 Aug 9. doi: 10.1093/nar/gkab679

PMCID:: PMC8450110

Abstract Article PDF–7.4M

Select item 80090483.

Impact of cytosine methylation on DNA binding specificities of human transcription factors

Yimeng Yin, Ekaterina Morgunova, Arttu Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, Pratyush K. Das, Teemu Kivioja, Kashyap Dave, Fan Zhong, Kazuhiro R. Nitta, Minna Taipale, Alexander Popov, Paul A. Ginno, Silvia Domcke, Jian Yan, Dirk Schübeler, Charles Vinson, Jussi Taipale

Science. Author manuscript; available in PMC 2021 Mar 30.

Published in final edited form as: Science. 2017 May 5; 356(6337): eaaj2239. doi: 10.1126/science.aaj2239

PMCID:: PMC8009048

Abstract Article PDF–2.6M

Select item 74040544.

Distal-Less Homeobox 5 Is a Therapeutic Target for Attenuating Hypertrophy and Apoptosis of Mesenchymal Progenitor Cells

John Twomey-Kozak, Salomi Desai, Wenguang Liu, Neill Y. Li, Nicholas Lemme, Qian Chen, Brett D. Owens, Chathuraka T. Jayasuriya

Int J Mol Sci. 2020 Jul; 21(14): 4823. Published online 2020 Jul 8. doi: 10.3390/ijms21144823

PMCID:: PMC7404054

Abstract Article PDF–2.6M

Select item 74022665.

APC/C-dependent control of gene expression and cell identity

Eugene Oh, Kevin G. Mark, Annamaria Mocciaro, Edmond R. Watson, J. Rajan Prabu, Denny D. Cha, Martin Kampmann, Nathan Gamarra, Coral Y. Zhou, Michael Rape

Nature. Author manuscript; available in PMC 2020 Aug 19.

Published in final edited form as: Nature. 2020 Mar; 579(7797): 136–140. Published online 2020 Feb 19. doi: 10.1038/s41586-020-2034-1

PMCID:: PMC7402266

Abstract Article PDF–5.3M

Select item 64334776.

Children's biobehavioral reactivity to challenge predicts DNA methylation in adolescence and emerging adulthood

Sarah J. Goodman, Danielle S. Roubinov, Nicole R. Bush, Mina Park, Pau Farré, Eldon Emberly, Clyde Hertzman, Marilyn J. Essex, Michael S. Kobor, W. Thomas Boyce

Dev Sci. 2019 Mar; 22(2): e12739. Published online 2018 Sep 21. doi: 10.1111/desc.12739

PMCID:: PMC6433477

Abstract Article PDF–2.1M

Select item 62358987.

Inhibition of STAT5A promotes osteogenesis by DLX5 regulation

Kyoung-Mi Lee, Kwang Hwan Park, Ji Suk Hwang, Moses Lee, Dong Suk Yoon, Hyun Aae Ryu, Ho Sun Jung, Ki Won Park, Jihyun Kim, Sahng Wook Park, Sung-Hwan Kim, Yong-Min Chun, Woo Jin Choi, Jin Woo Lee

Cell Death Dis. 2018 Nov; 9(11): 1136. Published online 2018 Nov 14. doi: 10.1038/s41419-018-1184-7

PMCID:: PMC6235898

Abstract Article PDF–2.0M

Select item 58443298.

Deletion of a Long-Range Dlx5 Enhancer Disrupts Inner Ear Development in Mice

Kenneth R. Johnson, Leona H. Gagnon, Cong Tian, Chantal M. Longo-Guess, Benjamin E. Low, Michael V. Wiles, Amy E. Kiernan

Genetics. 2018 Mar; 208(3): 1165–1179. Published online 2018 Jan 3. doi: 10.1534/genetics.117.300447

PMCID:: PMC5844329

Abstract Article PDF–1.5M

Select item 56718039.

Disturbed Placental Imprinting in Preeclampsia Leads to Altered Expression of DLX5, a Human-Specific Early Trophoblast Marker

Julianna Zadora, Manvendra Singh, Florian Herse, Lukasz Przybyl, Nadine Haase, Michaela Golic, Hong Wa Yung, Berthold Huppertz, Judith E. Cartwright, Guy Whitley, Guro M. Johnsen, Giovanni Levi, Annette Isbruch, Herbert Schulz, Friedrich C. Luft, Dominik N. Müller, Anne Cathrine Staff, Laurence D. Hurst, Ralf Dechend, Zsuzsanna Izsvák

Circulation. 2017 Nov 7; 136(19): 1824–1839. Published online 2017 Nov 7. doi: 10.1161/CIRCULATIONAHA.117.028110

Correction in:: Circulation. 2018 Oct 9; 138(15): e423.

PMCID:: PMC5671803

Abstract Article PDF–2.6M

Select item 562788310.

Distal-less homeobox 5 is a master regulator of the osteogenesis of human mesenchymal stem cells

June Seok Heo, Seung Gwan Lee, Hyun Ok Kim

Int J Mol Med. 2017 Nov; 40(5): 1486–1494. Published online 2017 Sep 19. doi: 10.3892/ijmm.2017.3142

PMCID:: PMC5627883

Abstract Article PDF–1.0M

Select item 549581311.

Increased methylation and decreased expression of homeobox genes TLX1, HOXA10 and DLX5 in human placenta are associated with trophoblast differentiation

Boris Novakovic, Thierry Fournier, Lynda K. Harris, Joanna James, Claire T. Roberts, Hannah E. J. Yong, Bill Kalionis, Danièle Evain-Brion, Peter R. Ebeling, Euan M. Wallace, Richard Saffery, Padma Murthi

Sci Rep. 2017; 7: 4523. Published online 2017 Jul 3. doi: 10.1038/s41598-017-04776-5

PMCID:: PMC5495813

Abstract Article PDF–2.7M

Select item 502888312.

Transcriptome analysis of periodontitis-associated fibroblasts by CAGE sequencing identified DLX5 and RUNX2 long variant as novel regulators involved in periodontitis

Masafumi Horie, Yoko Yamaguchi, Akira Saito, Takahide Nagase, Marina Lizio, Masayoshi Itoh, Hideya Kawaji, Timo Lassmann, Piero Carninci, Alistair R. R. Forrest, Yoshihide Hayashizaki, Tatsuo Suzutani, Kai Kappert, Patrick Micke, Mitsuhiro Ohshima

Sci Rep. 2016; 6: 33666. Published online 2016 Sep 20. doi: 10.1038/srep33666

PMCID:: PMC5028883

Abstract Article PDF–1.9M

Select item 499362313.

Methylation Alterations at Imprinted Genes Detected Among Long Term Shiftworkers

Daniel I. Jacobs, Johnni Hansen, Alan Fu, Richard G. Stevens, Anne Tjonneland, Ulla B. Vogel, Tongzhang Zheng, Yong Zhu

Environ Mol Mutagen. Author manuscript; available in PMC 2016 Aug 22.

Published in final edited form as: Environ Mol Mutagen. 2013 Mar; 54(2): 141–146. Published online 2012 Nov 28. doi: 10.1002/em.21752

PMCID:: PMC4993623

Abstract Article PDF–470K

Select item 482662814.

Dlx5 homedomain/DNA complex; Structure, binding and effect of mutations related to split-hand and foot malformation syndrome

Andrew Proudfoot, Herbert L. Axelrod, Michael Geralt, Robert J Fletterick, Fumiaki Yumoto, Ashley M. Deacon, Marc-André Elsliger, Ian A. Wilson, Kurt Wüthrich, Pedro Serrano

J Mol Biol. Author manuscript; available in PMC 2016 Apr 9.

Published in final edited form as: J Mol Biol. 2016 Mar 27; 428(6): 1130–1141. Published online 2016 Jan 29. doi: 10.1016/j.jmb.2016.01.023

PMCID:: PMC4826628

Abstract Article PDF–1.6M

Select item 433215015.

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes

Xu Li, Wenqi Wang, Jiadong Wang, Anna Malovannaya, Yuanxin Xi, Wei Li, Rudy Guerra, David H Hawke, Jun Qin, Junjie Chen

Mol Syst Biol. 2015 Jan; 11(1): 775. Published online 2015 Jan 21. doi: 10.15252/msb.20145504

PMCID:: PMC4332150

Abstract Article PDF–2.8M

Select item 413542316.

Exome sequencing reveals a heterozygous DLX5 mutation in a Chinese family with autosomal-dominant split-hand/foot malformation

Xue Wang, Qian Xin, Lin Li, Jiangxia Li, Changwu Zhang, Rongfang Qiu, Chenmin Qian, Hailing Zhao, Yongchao Liu, Shan Shan, Jie Dang, Xianli Bian, Changshun Shao, Yaoqin Gong, Qiji Liu

Eur J Hum Genet. 2014 Sep; 22(9): 1105–1110. Published online 2014 Feb 5. doi: 10.1038/ejhg.2014.7