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Items: 1 to 20 of 119

1.
SENP1 mediates zinc-induced ZnT6 deSUMOylation at Lys-409 involved in the regulation of zinc metabolism in Golgi apparatus
Chang-Chun Song, Tao Liu, Christer Hogstrand, Chong-Chao Zhong, Hua Zheng, Lv-Hui Sun, Zhi Luo
Cell Mol Life Sci. 2024 Dec; 81(1): 422. Published online 2024 Oct 5. doi: 10.1007/s00018-024-05452-4
PMCID:
PMC11455790
AbstractArticlePDF–3.6M
2.
Antagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability
Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold, Christopher E. Pearson
Cell. Author manuscript; available in PMC 2024 Oct 26.
Published in final edited form as: Cell. 2023 Oct 26; 186(22): 4898–4919.e25. Published online 2023 Oct 11. doi: 10.1016/j.cell.2023.09.008
PMCID:
PMC11209935
AbstractArticlePDF–3.0M
3.
N6-methyladenosine-modified SENP1, identified by IGF2BP3, is a novel molecular marker in acute myeloid leukemia and aggravates progression by activating AKT signal via de-SUMOylating HDAC2
Diguang Wen, Hang Xiao, Yueyi Gao, Hanqing Zeng, Jianchuan Deng
Mol Cancer. 2024; 23: 116. Published online 2024 May 31. doi: 10.1186/s12943-024-02013-y
PMCID:
PMC11141000
AbstractArticlePDF–13M
4.
SENP1-Mediated deSUMOylation Regulates the Tumor Remodeling of Glioma Stem Cells Under Hypoxic Stress
Ping Wen, Haoran Li, Liang Liu, Xinglei Liu, Zhipeng Xu, Jun Dong
Technol Cancer Res Treat. 2024; 23: 15330338241257490. Published online 2024 May 27. doi: 10.1177/15330338241257490
PMCID:
PMC11135080
AbstractArticlePDF–2.5M
5.
ER-export and ARFRP1/AP-1–dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication
Guy J. Pearson, Harriet V. Mears, Malgorzata Broncel, Ambrosius P. Snijders, David L. V. Bauer, Jeremy G. Carlton
Sci Adv. 2024 Apr 5; 10(14): eadl5012. Published online 2024 Apr 3. doi: 10.1126/sciadv.adl5012
PMCID:
PMC10990277
AbstractArticlePDF–3.9M
6.
SUMOylation modulates eIF5A activities in both yeast and pancreatic ductal adenocarcinoma cells
Rocío Seoane, Tomás Lama-Díaz, Antonia María Romero, Ahmed El Motiam, Arantxa Martínez-Férriz, Santiago Vidal, Yanis H. Bouzaher, María Blanquer, Rocío M. Tolosa, Juan Castillo Mewa, Manuel S. Rodríguez, Adolfo García-Sastre, Dimitris Xirodimas, James D. Sutherland, Rosa Barrio, Paula Alepuz, Miguel G. Blanco, Rosa Farràs, Carmen Rivas
Cell Mol Biol Lett. 2024; 29: 15. Published online 2024 Jan 16. doi: 10.1186/s11658-024-00533-5
PMCID:
PMC10790418
AbstractArticlePDF–3.6M
7.
SENP1 inhibits ferroptosis and promotes head and neck squamous cell carcinoma by regulating ACSL4 protein stability via SUMO1
Xianzhi Xu, Yiting Mao, Zhaowei Feng, Feng Dai, Teng Gu, Jiwei Zheng
Oncol Rep. 2024 Feb; 51(2): 34. Published online 2023 Dec 28. doi: 10.3892/or.2023.8693
PMCID:
PMC10777466
AbstractArticlePDF–17M
8.
A role and mechanism for redox sensing by SENP1 in β-cell responses to high fat feeding
Haopeng Lin, Kunimasa Suzuki, Nancy Smith, Xi Li, Lisa Nalbach, Sonia Fuentes, Aliya F. Spigelman, Xiao-Qing Dai, Austin Bautista, Mourad Ferdaoussi, Saloni Aggarwal, Andrew R. Pepper, Leticia P. Roma, Emmanuel Ampofo, Wen-hong Li, Patrick E. MacDonald
Nat Commun. 2024; 15: 334. Published online 2024 Jan 6. doi: 10.1038/s41467-023-44589-x
PMCID:
PMC10771529
AbstractArticlePDF–3.6M
9.
Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates
Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert
Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644
PMCID:
PMC10565876
AbstractArticlePDF–3.7M
10.
SUMOylation of the ubiquitin ligase component KEAP1 at K39 upregulates NRF2 and its target function in lung cancer cell proliferation
Hao Yang, Yuzhang Du, Xuefeng Fei, Shu Huang, Maimaitiaili Yimiti, Xiaobao Yang, Junrui Ma, Shuhui Li, Huxidanmu Tuoheniyazi, Yanan Zhao, Zhidong Gu, Dakang Xu
J Biol Chem. 2023 Oct; 299(10): 105215. Published online 2023 Sep 1. doi: 10.1016/j.jbc.2023.105215
PMCID:
PMC10556770
AbstractArticlePDF–2.4M
11.
Native Semisynthesis of Isopeptide-Linked Substrates for Specificity Analysis of Deubiquitinases and Ubl Proteases
Zhou Zhao, Rachel O’Dea, Kim Wendrich, Nafizul Kazi, Malte Gersch
J Am Chem Soc. 2023 Sep 27; 145(38): 20801–20812. Published online 2023 Sep 15. doi: 10.1021/jacs.3c04062
PMCID:
PMC10540217
AbstractArticlePDF–7.6M
12.
MYB regulates the SUMO protease SENP1 and its novel interaction partner UXT, modulating MYB target genes and the SUMO landscape
Roza Berhanu Lemma, Marit Ledsaak, Bettina Maria Fuglerud, Fernando Rodríguez-Castañeda, Ragnhild Eskeland, Odd Stokke Gabrielsen
J Biol Chem. 2023 Sep; 299(9): 105062. Published online 2023 Jul 17. doi: 10.1016/j.jbc.2023.105062
PMCID:
PMC10463205
AbstractArticlePDF–4.6M
13.
RBM33 is a unique m6A RNA binding protein that regulates ALKBH5 Demethylase Activity and Substrate Selectivity
Fang Yu, Allen C Zhu, Shun Liu, Boyang Gao, Yuzhi Wang, Nelli Khudaverdyan, Chunjie Yu, Qiong Wu, Yunhan Jiang, Jikui Song, Lingtao Jin, Chuan He, Zhijian Qian
Mol Cell. Author manuscript; available in PMC 2024 Jun 15.
Published in final edited form as: Mol Cell. 2023 Jun 15; 83(12): 2003–2019.e6. Published online 2023 May 30. doi: 10.1016/j.molcel.2023.05.010
PMCID:
PMC10330838
AbstractArticlePDF–2.8M
14.
The p97/VCP segregase is essential for arsenic-induced degradation of PML and PML-RARA
Ellis G. Jaffray, Michael H. Tatham, Barbara Mojsa, Magda Liczmanska, Alejandro Rojas-Fernandez, Yili Yin, Graeme Ball, Ronald T. Hay
J Cell Biol. 2023 Apr 3; 222(4): e202201027. Published online 2023 Feb 28. doi: 10.1083/jcb.202201027
PMCID:
PMC10005898
AbstractArticlePDF–6.7M
15.
Dynamic SUMOylation of MORC2 orchestrates chromatin remodelling and DNA repair in response to DNA damage and drives chemoresistance in breast cancer
Fang-Lin Zhang, Shao-Ying Yang, Li Liao, Tai-Mei Zhang, Yin-Ling Zhang, Shu-Yuan Hu, Ling Deng, Min-Ying Huang, Lisa Andriani, Xiao-Yan Ma, Zhi-Min Shao, Da-Qiang Li
Theranostics. 2023; 13(3): 973–990. Published online 2023 Jan 22. doi: 10.7150/thno.79688
PMCID:
PMC9925317
AbstractArticlePDF–6.7M
16.
TBK1 posphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1
Jianwen Zhou, Nikoline Lander Rasmussen, Hallvard Lauritz Olsvik, Vyacheslav Akimov, Zehan Hu, Gry Evjen, Stéphanie Kaeser-Pebernard, Devanarayanan Siva Sankar, Carole Roubaty, Pauline Verlhac, Nicole van de Beek, Fulvio Reggiori, Yakubu Princely Abudu, Blagoy Blagoev, Trond Lamark, Terje Johansen, Jörn Dengjel
J Cell Biol. 2023 Feb 6; 222(2): e202108144. Published online 2022 Dec 27. doi: 10.1083/jcb.202108144
PMCID:
PMC9797988
AbstractArticlePDF–6.9M
17.
A whole genome CRISPR screen identifies AHR loss as a mechanism of resistance to a PARP7 inhibitor
Huadong Chen, Morgan E. Diolaiti, Patrick C. O’Leary, Ajda Rojc, Nevan J. Krogan, Minkyu Kim, Alan Ashworth
Mol Cancer Ther. Author manuscript; available in PMC 2023 Jan 5.
Published in final edited form as: Mol Cancer Ther. 2022 Jul 5; 21(7): 1076–1089. doi: 10.1158/1535-7163.MCT-21-0841
PMCID:
PMC9769698
AbstractArticlePDF–2.7M
18.
Insights into the Allosteric Effect of SENP1 Q597A Mutation on the Hydrolytic Reaction of SUMO1 via an Integrated Computational Study
Mingfei Ji, Zongtao Chai, Jie Chen, Gang Li, Qiang Li, Miao Li, Yelei Ding, Shaoyong Lu, Guanqun Ju, Jianquan Hou
Molecules. 2022 Jul; 27(13): 4149. Published online 2022 Jun 28. doi: 10.3390/molecules27134149
PMCID:
PMC9268427
AbstractArticlePDF–4.9M
19.
SARS-CoV-2 N Protein Antagonizes Stress Granule Assembly and IFN Production by Interacting with G3BPs to Facilitate Viral Replication
Hainan Liu, Yu Bai, Xun Zhang, Ting Gao, Yue Liu, Entao Li, Xuefeng Wang, Zheng Cao, Lin Zhu, Qincai Dong, Yong Hu, Guangfei Wang, Caiwei Song, Xiayang Niu, Tong Zheng, Di Wang, Zijing Liu, Yanwen Jin, Ping Li, Xiuwu Bian, Cheng Cao, Xuan Liu
J Virol. 2022 Jun; 96(12): e00412-22. Published online 2022 Jun 2. doi: 10.1128/jvi.00412-22
PMCID:
PMC9215227
AbstractArticlePDF–4.2M
20.
SENP1 promotes triple-negative breast cancer invasion and metastasis via enhancing CSN5 transcription mediated by GATA1 deSUMOylation
Yongchang Gao, Rongrong Wang, Jianjing Liu, Ke Zhao, Xiaolong Qian, Xianghui He, Hong Liu
Int J Biol Sci. 2022; 18(5): 2186–2201. Published online 2022 Mar 6. doi: 10.7150/ijbs.60594
PMCID:
PMC8935229
AbstractArticlePDF–4.2M

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