PMC Links for GEO Profiles (Select 132343487) - PMC

Links from GEO Profiles

Items: 1 to 20 of 165

<< First< Prev

Page of 9

Select item 114476911.

Bruton Tyrosine Kinase Inhibition Decreases Inflammation and Differentially Impacts Phagocytosis and Cellular Metabolism in Mouse- and Human-derived Myeloid Cells

Rochelle Y. Benoit, Jennifer L. Zagrodnik, Samantha J. Carew, Craig S. Moore

Immunohorizons. 2024 Sep; 8(9): 652–667. Published online 2024 Sep 11. doi: 10.4049/immunohorizons.2400045

PMCID:: PMC11447691

Abstract Article PDF–2.8M

Select item 113957592.

Transcriptomic and proteomic differences in BTK-WT and BTK-mutated CLL and their changes during therapy with pirtobrutinib

Burcu Aslan, Ganiraju Manyam, Lakesla R. Iles, Shady I. Tantawy, Sai Prasad Desikan, William G. Wierda, Varsha Gandhi

Blood Adv. 2024 Sep 10; 8(17): 4487–4501. Published online 2024 Jul 9. doi: 10.1182/bloodadvances.2023012360

PMCID:: PMC11395759

Abstract Article PDF–2.4M

Select item 112865063.

Mutation in Bruton Tyrosine Kinase (BTK) A428D confers resistance To BTK-degrader therapy in chronic lymphocytic leukemia

Richard L. Wong, Michael Y. Choi, Huan-You Wang, Thomas J. Kipps

Leukemia. 2024; 38(8): 1818–1821. Published online 2024 Jul 24. doi: 10.1038/s41375-024-02317-4

PMCID:: PMC11286506

Abstract Article PDF–680K

Select item 109227054.

Single-Cell RNA-Seq Analysis of Patient Myeloid-Derived Suppressor Cells and the Response to Inhibition of Bruton’s Tyrosine Kinase

Himanshu Savardekar, Carter Allen, Hyeongseon Jeon, Jianying Li, Dionisia Quiroga, Emily Schwarz, Richard C. Wu, Sara Zelinskas, Gabriella Lapurga, Alexander Abreo, Andrew Stiff, Jami Shaffer, Bradley W. Blaser, Matthew Old, Robert Wesolowski, Gang Xin, Kari L. Kendra, Dongjun Chung, William E. Carson, III

Mol Cancer Res. Author manuscript; available in PMC 2024 Sep 1.

Published in final edited form as: Mol Cancer Res. 2024 Mar 1; 22(3): 308–321. doi: 10.1158/1541-7786.MCR-22-0572

PMCID:: PMC10922705

Abstract Article PDF–2.2M

Select item 107440745.

Identification of the Axis β-Catenin–BTK in the Dynamic Adhesion of Chronic Lymphocytic Leukemia Cells to Their Microenvironment

Imane Mihoub, Tareck Rharass, Souhaïl Ouriemmi, Antonin Oudar, Laure Aubard, Valérie Gratio, Gregory Lazarian, Jordan Ferreira, Elisabetta Dondi, Florence Cymbalista, Vincent Levy, Fanny Baran-Marszak, Nadine Varin-Blank, Dominique Ledoux, Christine Le Roy, Laura Gardano

Int J Mol Sci. 2023 Dec; 24(24): 17623. Published online 2023 Dec 18. doi: 10.3390/ijms242417623

PMCID:: PMC10744074

Abstract Article PDF–2.7M

Select item 107424736.

Resisting the Resistance: Navigating BTK Mutations in Chronic Lymphocytic Leukemia (CLL)

Alexandra Chirino, Skye Montoya, Anita Safronenka, Justin Taylor

Genes (Basel) 2023 Dec; 14(12): 2182. Published online 2023 Dec 6. doi: 10.3390/genes14122182

PMCID:: PMC10742473

Abstract Article PDF–4.3M

Select item 106794517.

Expression of Bruton´s tyrosine kinase in different type of brain lesions of multiple sclerosis patients and during experimental demyelination

Maria L. Elkjaer, Mie R. Waede, Christina Kingo, Karina Damsbo, Zsolt Illes

Front Immunol. 2023; 14: 1264128. Published online 2023 Nov 13. doi: 10.3389/fimmu.2023.1264128

PMCID:: PMC10679451

Abstract Article PDF–734K

Select item 104876128.

Influence of Bruton’s Tyrosine Kinase (BTK) on Epithelial–Mesenchymal Transition (EMT) Processes and Cancer Stem Cell (CSC) Enrichment in Head and Neck Squamous Cell Carcinoma (HNSCC)

Franziska Leichtle, Annika C. Betzler, Carlotta Eizenberger, Kristina Lesakova, Jasmin Ezić, Robert Drees, Jens Greve, Patrick J. Schuler, Simon Laban, Thomas K. Hoffmann, Nils Cordes, Marialuisa Lavitrano, Emanuela Grassilli, Cornelia Brunner

Int J Mol Sci. 2023 Sep; 24(17): 13133. Published online 2023 Aug 23. doi: 10.3390/ijms241713133

PMCID:: PMC10487612

Abstract Article PDF–3.5M

Select item 104571699.

Overexpression of Bruton Tyrosine Kinase Inhibits the Proliferation, Migration, and Invasion of Non-Small Cell Lung Cancer Cells

Wenjia Ren, Cheng Yue, Linjun Liu, Licheng Du, Ke Xu, Yubai Zhou

Anal Cell Pathol (Amst) 2023; 2023: 3377316. Published online 2023 Aug 18. doi: 10.1155/2023/3377316

PMCID:: PMC10457169

Abstract Article PDF–1.9M

Select item 1027954710.

BTK and PLCG2 remain unmutated in one-third of patients with CLL relapsing on ibrutinib

Silvia Bonfiglio, Lesley-Ann Sutton, Viktor Ljungström, Antonella Capasso, Tatjana Pandzic, Simone Weström, Hassan Foroughi-Asl, Aron Skaftason, Anna Gellerbring, Anna Lyander, Francesca Gandini, Gianluca Gaidano, Livio Trentin, Lisa Bonello, Gianluigi Reda, Csaba Bödör, Niki Stavroyianni, Constantine S. Tam, Roberto Marasca, Francesco Forconi, Panayiotis Panayiotidis, Ingo Ringshausen, Ozren Jaksic, Anna Maria Frustaci, Sunil Iyengar, Marta Coscia, Stephen P. Mulligan, Loïc Ysebaert, Vladimir Strugov, Carolina Pavlovsky, Renata Walewska, Anders Österborg, Diego Cortese, Pamela Ranghetti, Panagiotis Baliakas, Kostas Stamatopoulos, Lydia Scarfò, Richard Rosenquist, Paolo Ghia

Blood Adv. 2023 Jun 27; 7(12): 2794–2806. Published online 2023 Jan 31. doi: 10.1182/bloodadvances.2022008821

PMCID:: PMC10279547

Abstract Article PDF–430K

Select item 1023042911.

Concomitant targeting of FLT3 and BTK overcomes FLT3 inhibitor resistance in acute myeloid leukemia through the inhibition of autophagy

Weiguo Zhang, Guopan Yu, Hongying Zhang, Mahesh Basyal, Charlie Ly, Bin Yuan, Vivian Ruvolo, Sujan Piya, Seemana Bhattacharya, Qi Zhang, Gautam Borthakur, Venkata L. Battula, Marina Konopleva, William G. Rice, Michael Andreeff

Haematologica. 2023 Jun 1; 108(6): 1500–1514. Published online 2022 Oct 13. doi: 10.3324/haematol.2022.280884

PMCID:: PMC10230429

Abstract Article PDF–3.0M

Select item 1017836112.

Differential Regulation of GPVI-Induced Btk and Syk Activation by PKC, PKA and PP2A in Human Platelets

Pengyu Zhang, Fiorella A. Solari, Johan W. M. Heemskerk, Marijke J. E. Kuijpers, Albert Sickmann, Ulrich Walter, Kerstin Jurk

Int J Mol Sci. 2023 May; 24(9): 7776. Published online 2023 Apr 24. doi: 10.3390/ijms24097776

PMCID:: PMC10178361

Abstract Article PDF–3.2M

Select item 1007290613.

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong

Mol Cell. Author manuscript; available in PMC 2023 Apr 4.

Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015

PMCID:: PMC10072906

Abstract Article PDF–4.2M

Select item 1001341414.

ROR1/CD19 receptor complex promotes growth of mantle cell lymphoma cells independently of the B Cell Receptor-BTK signaling pathway

Qian Zhang, Hong Y Wang, Xiaobin Liu, Selene Nunez-Cruz, Mowafaq Jillab, Olga Melnikov, Kavindra Nath, Jerry Glickson, Mariusz A Wasik

J Immunol. Author manuscript; available in PMC 2023 Mar 14.

Published in final edited form as: J Immunol. 2019 Oct 15; 203(8): 2043–2048. Published online 2019 Sep 18. doi: 10.4049/jimmunol.1801327

PMCID:: PMC10013414

Abstract Article PDF–808K

Select item 988838215.

Cotargeting of BTK and MALT1 overcomes resistance to BTK inhibitors in mantle cell lymphoma

Vivian Changying Jiang, Yang Liu, Junwei Lian, Shengjian Huang, Alexa Jordan, Qingsong Cai, Ruitao Lin, Fangfang Yan, Joseph McIntosh, Yijing Li, Yuxuan Che, Zhihong Chen, Jovanny Vargas, Maria Badillo, John Nelson Bigcal, Heng-Huan Lee, Wei Wang, Yixin Yao, Lei Nie, Christopher R. Flowers, Michael Wang

J Clin Invest. 2023 Feb 1; 133(3): e165694. Published online 2023 Feb 1. doi: 10.1172/JCI165694

PMCID:: PMC9888382

Abstract Article PDF–2.3M

Select item 924788216.

Palmitoylation of the Alternative Amino Terminus of the BTK-C Isoform Controls Subcellular Distribution and Signaling

MOSTAFA KOKABEE, XIANHUI WANG, ELENA VOORAND, EDEN ALIN, LEILA KOKABEE, FAIZA KHAN, SOPHIA DESROSIERS, DOUGLAS S. CONKLIN

Cancer Genomics Proteomics. 2022 Jul-Aug; 19(4): 415–427. Published online 2022 Jul 3. doi: 10.21873/cgp.20329

PMCID:: PMC9247882

Abstract Article PDF–5.2M

Select item 911756717.

Btk supports autoreactive B cell development and protects against apoptosis but is expendable for antigen-presentation

Lindsay E. Nyhoff, Amber S. Griffith, Emily S. Clark, James W. Thomas, Wasif N. Khan, Peggy L. Kendall

J Immunol. Author manuscript; available in PMC 2022 Dec 15.

Published in final edited form as: J Immunol. 2021 Dec 15; 207(12): 2922–2932. Published online 2021 Nov 19. doi: 10.4049/jimmunol.2000558

PMCID:: PMC9117567

Abstract Article PDF–2.1M

Select item 910630318.

Genome-wide CRISPR screens using isogenic cells reveal vulnerabilities conferred by loss of tumor suppressors

Xu Feng, Mengfan Tang, Merve Dede, Dan Su, Guangsheng Pei, Dadi Jiang, Chao Wang, Zhen Chen, Mi Li, Litong Nie, Yun Xiong, Siting Li, Jeong-Min Park, Huimin Zhang, Min Huang, Klaudia Szymonowicz, Zhongming Zhao, Traver Hart, Junjie Chen

Sci Adv. 2022 May; 8(19): eabm6638. Published online 2022 May 13. doi: 10.1126/sciadv.abm6638

PMCID:: PMC9106303

Abstract Article PDF–918K

Select item 907414319.

Mechanisms of Resistance to Noncovalent Bruton’s Tyrosine Kinase Inhibitors

Eric Wang, Xiaoli Mi, Meghan C. Thompson, Skye Montoya, Ryan Q. Notti, Jumana Afaghani, Benjamin H. Durham, Alex Penson, Matthew T. Witkowski, Sydney X. Lu, Jessie Bourcier, Simon J. Hogg, Caroline Erickson, Dan Cui, Hana Cho, Michael Singer, Tulasigeri M. Totiger, Sana Chaudhry, Mark Geyer, Alvaro Alencar, Adam J. Linley, M. Lia Palomba, Catherine C. Coombs, Jae H. Park, Andrew Zelenetz, Lindsey Roeker, Mary Rosendahl, Donald E. Tsai, Kevin Ebata, Barbara Brandhuber, David M. Hyman, Iannis Aifantis, Anthony Mato, Justin Taylor, Omar Abdel-Wahab

N Engl J Med. Author manuscript; available in PMC 2022 May 6.

Published in final edited form as: N Engl J Med. 2022 Feb 24; 386(8): 735–743. doi: 10.1056/NEJMoa2114110

PMCID:: PMC9074143

Abstract Article PDF–1014K

Select item 874479620.

Spontaneous Platelet Aggregation in Blood Is Mediated by FcγRIIA Stimulation of Bruton’s Tyrosine Kinase

Rundan Duan, Luise Goldmann, Ya Li, Christian Weber, Wolfgang Siess, Philipp von Hundelshausen

Int J Mol Sci. 2022 Jan; 23(1): 76. Published online 2021 Dec 22. doi: 10.3390/ijms23010076

PMCID:: PMC8744796

Abstract Article PDF–1.1M

PMC

Result Filters

Article attributes

Text availability

Publication date

Custom date range

Research Funder

Additional filters

Display Settings:

Send to:

Links from GEO Profiles

Items: 1 to 20 of 165

Display Settings:

Send to:

Supplemental Content

Find related data

Recent activity