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Items: 1 to 20 of 56

1.
Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell
Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low
Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120
PMCID:
PMC10151615
AbstractArticlePDF–2.9M
2.
Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity
Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong
Mol Cell. Author manuscript; available in PMC 2023 Apr 4.
Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015
PMCID:
PMC10072906
AbstractArticlePDF–4.2M
3.
Activin A receptor type 2A mutation affects the tumor biology of microsatellite instability-high gastric cancer
Kizuki Yuza, Masayuki Nagahashi, Hiroshi Ichikawa, Takaaki Hanyu, Masato Nakajima, Yoshifumi Shimada, Takashi Ishikawa, Jun Sakata, Shiho Takeuchi, Shujiro Okuda, Yasunobu Matsuda, Manabu Abe, Kenji Sakimura, Kazuaki Takabe, Toshifumi Wakai
J Gastrointest Surg. Author manuscript; available in PMC 2022 Sep 1.
Published in final edited form as: J Gastrointest Surg. 2021 Sep; 25(9): 2231–2241. Published online 2021 Jan 8. doi: 10.1007/s11605-020-04889-9
PMCID:
PMC8728635
AbstractArticlePDF–1016K
4.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
5.
Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases
Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger
Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001
PMCID:
PMC7427327
AbstractArticle
6.
Synovial chondromatosis and soft tissue chondroma: extra-osseous cartilaginous tumours defined by FN1 gene rearrangement
Fernanda Amary, Luis Perez-Casanova, Hongtao Ye, Lucia Cottone, Anna Strobl, Paul Cool, Elena Miranda, Fitim Berisha, William Aston, Maia Rocha, Paul O’Donnell, Nischalan Pillay, Roberto Tirabosco, Daniel Baumhoer, Edward S Hookway, Adrienne M Flanagan
Mod Pathol. Author manuscript; available in PMC 2019 Nov 28.
Published in final edited form as: Mod Pathol. 2019 Jun 14; 32(12): 1762–1771. Published online 2019 Jul 4. doi: 10.1038/s41379-019-0315-8
PMCID:
PMC6882679
AbstractArticlePDF–1.6M
7.
Structural characterization of an activin class ternary receptor complex reveals a third paradigm for receptor specificity
Erich J. Goebel, Richard A. Corpina, Cynthia S. Hinck, Magdalena Czepnik, Roselyne Castonguay, Rosa Grenha, Angela Boisvert, Gabriella Miklossy, Paul T. Fullerton, Martin M. Matzuk, Vincent J. Idone, Aris N. Economides, Ravindra Kumar, Andrew P. Hinck, Thomas B. Thompson
Proc Natl Acad Sci U S A. 2019 Jul 30; 116(31): 15505–15513. Published online 2019 Jul 17. doi: 10.1073/pnas.1906253116
PMCID:
PMC6681762
AbstractArticlePDF–1.8M
8.
The Activin Receptor, Activin-Like Kinase 4, Mediates Toxoplasma Gondii Activation of Hypoxia Inducible Factor-1
Agnieszka Lis, Mandi Wiley, Joan Vaughan, Peter C. Gray, Ira J. Blader
Front Cell Infect Microbiol. 2019; 9: 36. Published online 2019 Mar 5. doi: 10.3389/fcimb.2019.00036
PMCID:
PMC6411701
AbstractArticlePDF–2.7M
9.
Non-additive effects of ACVR2A in preeclampsia in a Philippine population
Melissa D. Amosco, Gloria R. Tavera, Van Anthony M. Villar, Justin Michael A. Naniong, Lara Marie G. David-Bustamante, Scott M. Williams, Pedro A. Jose, Cynthia P. Palmes-Saloma
BMC Pregnancy Childbirth. 2019; 19: 11. Published online 2019 Jan 8. doi: 10.1186/s12884-018-2152-z
PMCID:
PMC6323705
AbstractArticlePDF–703K
10.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
11.
Biochemical and Cellular Analysis Reveals Ligand Binding Specificities, a Molecular Basis for Ligand Recognition, and Membrane Association-dependent Activities of Cripto-1 and Cryptic
Senem Aykul, Anthony Parenti, Kit Yee Chu, Jake Reske, Monique Floer, Amy Ralston, Erik Martinez-Hackert
J Biol Chem. 2017 Mar 10; 292(10): 4138–4151. Published online 2017 Jan 26. doi: 10.1074/jbc.M116.747501
PMCID:
PMC5354514
AbstractArticlePDF–3.1M
12.
TGF-beta receptor mediated telomerase inhibition, telomere shortening and breast cancer cell senescence
Lucy Cassar, Craig Nicholls, Alex R. Pinto, Ruping Chen, Lihui Wang, He Li, Jun-Ping Liu
Protein Cell. 2017 Jan; 8(1): 39–54. Published online 2016 Sep 30. doi: 10.1007/s13238-016-0322-1
PMCID:
PMC5233610
AbstractArticlePDF–3.2M
13.
Pleiotropic Associations of Allelic Variants in a 2q22 Region with Risks of Major Human Diseases and Mortality
Alexander M. Kulminski, Liang He, Irina Culminskaya, Yury Loika, Yelena Kernogitski, Konstantin G. Arbeev, Elena Loiko, Liubov Arbeeva, Olivia Bagley, Matt Duan, Arseniy Yashkin, Fang Fang, Mikhail Kovtun, Svetlana V. Ukraintseva, Deqing Wu, Anatoliy I. Yashin
PLoS Genet. 2016 Nov; 12(11): e1006314. Published online 2016 Nov 10. doi: 10.1371/journal.pgen.1006314
PMCID:
PMC5104356
AbstractArticlePDF–1.9M
14.
Rapid Activation of Bone Morphogenic Protein 9 by Receptor-mediated Displacement of Pro-domains
Yvonne Kienast, Ute Jucknischke, Stefan Scheiblich, Martina Thier, Mariana de Wouters, Alexander Haas, Christian Lehmann, Verena Brand, Dirk Bernicke, Konrad Honold, Stefan Lorenz
J Biol Chem. 2016 Feb 12; 291(7): 3395–3410. Published online 2015 Dec 16. doi: 10.1074/jbc.M115.680009
PMCID:
PMC4751383
AbstractArticlePDF–4.0M
15.
The BioPlex Network: A Systematic Exploration of the Human Interactome
Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2016 Jul 16.
Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043
PMCID:
PMC4617211
AbstractArticlePDF–2.2M
16.
Activin A inhibits BMP-signaling by binding ACVR2A and ACVR2B
Oddrun Elise Olsen, Karin Fahl Wader, Hanne Hella, Anne Kærsgaard Mylin, Ingemar Turesson, Ingerid Nesthus, Anders Waage, Anders Sundan, Toril Holien
Cell Commun Signal. 2015; 13: 27. Published online 2015 Jun 6. doi: 10.1186/s12964-015-0104-z
PMCID:
PMC4467681
AbstractArticlePDF–1.3M
17.
Small Molecules Dorsomorphin and LDN-193189 Inhibit Myostatin/GDF8 Signaling and Promote Functional Myoblast Differentiation
Daniel Horbelt, Jan H. Boergermann, Apirat Chaikuad, Ivan Alfano, Eleanor Williams, Ilya Lukonin, Tobias Timmel, Alex N. Bullock, Petra Knaus
J Biol Chem. 2015 Feb 6; 290(6): 3390–3404. Published online 2014 Nov 3. doi: 10.1074/jbc.M114.604397
PMCID:
PMC4319009
AbstractArticlePDF–3.5M
18.
Influence of target gene mutations on survival, stage and histology in sporadic microsatellite unstable colon cancers
Barbara Jung, E. Julieta Smith, Ryan T. Doctolero, Pascal Gervaz, Julio C. Alonso, Katsumi Miyai, Temitope Keku, Robert S. Sandler, John M. Carethers
Int J Cancer. Author manuscript; available in PMC 2014 Sep 5.
Published in final edited form as: Int J Cancer. 2006 May 15; 118(10): 2509–2513. doi: 10.1002/ijc.21710
PMCID:
PMC4155491
AbstractArticlePDF–95K
19.
Activin Type 2 Receptor Restoration in MSI-H Colon Cancer Suppresses Growth and Enhances Migration With Activin
BARBARA H. JUNG, STAYCE E. BECK, JENNIFER CABRAL, EDDY CHAU, BETTY L. CABRERA, ANTONIO FIORINO, E. JULIETA SMITH, MELANIE BOCANEGRA, JOHN M. CARETHERS
Gastroenterology. Author manuscript; available in PMC 2014 Sep 4.
Published in final edited form as: Gastroenterology. 2007 Feb; 132(2): 633–644. Published online 2006 Nov 16. doi: 10.1053/j.gastro.2006.11.018
PMCID:
PMC4154562
AbstractArticlePDF–865K
20.
Endoglin-Mediated Suppression of Prostate Cancer Invasion Is Regulated by Activin and Bone Morphogenetic Protein Type II Receptors
Michael J. Breen, Diarmuid M. Moran, Wenzhe Liu, Xiaoke Huang, Calvin P. H. Vary, Raymond C. Bergan
PLoS One. 2013; 8(8): e72407. Published online 2013 Aug 13. doi: 10.1371/journal.pone.0072407
PMCID:
PMC3742533
AbstractArticlePDF–3.1M

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