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Select item 101917901.

TCN1 Deficiency Inhibits the Malignancy of Colorectal Cancer Cells by Regulating the ITGB4 Pathway

Xinqiang Zhu, Xuetong Jiang, Qinglin Zhang, Hailong Huang, Xiaohong Shi, Daorong Hou, Chungen Xing

Gut Liver. 2023 May 15; 17(3): 412–429. Published online 2022 Jun 10. doi: 10.5009/gnl210494

PMCID:: PMC10191790

Abstract Article PDF–13M

Select item 81650302.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 73977563.

Clinicopathological Analysis and Prognostic Assessment of Transcobalamin I (TCN1) in Patients with Colorectal Tumors

Xinqiang Zhu, Kui Yi, Daorong Hou, Hailong Huang, Xuetong Jiang, Xiaohong Shi, Chungen Xing

Med Sci Monit. 2020; 26: e923828-1–e923828-9. Prepublished online 2020 May 27. Published online 2020 Jul 23. doi: 10.12659/MSM.923828

PMCID:: PMC7397756

Abstract Article PDF–974K

Select item 60143604.

A common TCN1 loss-of-function variant is associated with lower vitamin B₁₂ concentration in African Americans

Yao Hu, Laura M. Raffield, Linda M. Polfus, Arden Moscati, Girish Nadkarni, Michael H. Preuss, Xue Zhong, Qiang Wei, Stephen S. Rich, Yun Li, James G. Wilson, Adolfo Correa, Ruth J. F. Loos, Bingshan Li, Paul L. Auer, Alex P. Reiner, the NHLBI Trans-Omics for Precision Medicine Consortium

Blood. 2018 Jun 21; 131(25): 2859–2863. Prepublished online 2018 May 15. doi: 10.1182/blood-2018-03-841023

PMCID:: PMC6014360

Article

Select item 55316115.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 49471546.

Structural basis of transcobalamin recognition by human CD320 receptor

Amer Alam, Jae-Sung Woo, Jennifer Schmitz, Bernadette Prinz, Katharina Root, Fan Chen, Joël S. Bloch, Renato Zenobi, Kaspar P. Locher

Nat Commun. 2016; 7: 12100. Published online 2016 Jul 14. doi: 10.1038/ncomms12100

PMCID:: PMC4947154

Abstract Article PDF–1.1M

Select item 41236057.

Genetic Associations with Plasma B12, B6, and Folate Levels in an Ischemic Stroke Population from the Vitamin Intervention for Stroke Prevention (VISP) Trial

Keith L. Keene, Wei-Min Chen, Fang Chen, Stephen R. Williams, Stacey D. Elkhatib, Fang-Chi Hsu, Josyf C. Mychaleckyj, Kimberly F. Doheny, Elizabeth W. Pugh, Hua Ling, Cathy C. Laurie, Stephanie M. Gogarten, Ebony B. Madden, Bradford B. Worrall, Michele M. Sale

Front Public Health. 2014; 2: 112. Published online 2014 Aug 6. doi: 10.3389/fpubh.2014.00112

PMCID:: PMC4123605

Abstract Article PDF–874K

Select item 39387498.

Transcriptomic Profile Reveals Gender-Specific Molecular Mechanisms Driving Multiple Sclerosis Progression

Haritz Irizar, Maider Muñoz-Culla, Lucia Sepúlveda, Matías Sáenz-Cuesta, Álvaro Prada, Tamara Castillo-Triviño, Gorka Zamora-López, Adolfo López de Munain, Javier Olascoaga, David Otaegui

PLoS One. 2014; 9(2): e90482. Published online 2014 Feb 28. doi: 10.1371/journal.pone.0090482

PMCID:: PMC3938749

Abstract Article PDF–4.6M

Select item 38337079.

Investigation of CBS, MTR, RFC-1 and TC Polymorphisms as Maternal Risk Factors for Down Syndrome

N. Fintelman-Rodrigues, J. C. Corrêa, J. M. Santos, M. M. G. Pimentel, C. B. Santos-Rebouças

Dis Markers. 2009; 26(4): 155–161. Published online 2009 Sep 3. doi: 10.3233/DMA-2009-0626

PMCID:: PMC3833707

Summary PDF–288K

Select item 375720810.

Structural Basis for Universal Corrinoid Recognition by the Cobalamin Transport Protein Haptocorrin

Evelyne Furger, Dominik C. Frei, Roger Schibli, Eliane Fischer, Andrea E. Prota

J Biol Chem. 2013 Aug 30; 288(35): 25466–25476. Published online 2013 Jul 11. doi: 10.1074/jbc.M113.483271

PMCID:: PMC3757208

Abstract Article PDF–4.8M

Select item 346048611.

A Single Rainbow Trout Cobalamin-binding Protein Stands in for Three Human Binders

Eva Greibe, Sergey Fedosov, Boe S. Sorensen, Peter Højrup, Steen S. Poulsen, Ebba Nexo

J Biol Chem. 2012 Sep 28; 287(40): 33917–33925. Published online 2012 Aug 7. doi: 10.1074/jbc.M112.398016

PMCID:: PMC3460486

Abstract Article PDF–1.9M

Select item 330794712.

Elevated Vitamin B₁₂ Levels in Autoimmune Lymphoproliferative Syndrome Attributable to Elevated Haptocorrin in Lymphocytes

Raffick A.R. Bowen, Kennichi C. Dowdell, Janet K. Dale, Steven K. Drake, Thomas A. Fleisher, Glen L. Hortin, Alan T. Remaley, Ebba Nexo, V. Koneti Rao

Clin Biochem. Author manuscript; available in PMC 2013 Apr 1.

Published in final edited form as: Clin Biochem. 2012 Apr; 45(6): 490–492. Published online 2012 Jan 28. doi: 10.1016/j.clinbiochem.2012.01.016

PMCID:: PMC3307947

Abstract Article PDF–512K

Select item 317805913.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 306601514.

Polymorphisms in DNA Repair and One-Carbon Metabolism Genes and Overall Survival in Diffuse Large B-Cell Lymphoma (DLBCL) and Follicular Lymphoma

Sophia S Wang, Matthew J Maurer, Lindsay M Morton, Thomas M Habermann, Scott Davis, Wendy Cozen, Charles F Lynch, Richard K Severson, Nathaniel Rothman, Stephen J Chanock, Patricia Hartge, James R Cerhan

Leukemia. Author manuscript; available in PMC 2011 Mar 29.

Published in final edited form as: Leukemia. 2009 Mar; 23(3): 596–602. Published online 2008 Oct 2. doi: 10.1038/leu.2008.240

PMCID:: PMC3066015

Article PDF–776K

Select item 304224715.

TRANSCOBALAMIN-II VARIANTS, DECREASED VITAMIN B12 AVAILABILITY AND INCREASED RISK OF FRAILTY

A.M. MATTEINI, J.D. WALSTON, K. BANDEEN-ROCHE, D.E. ARKING, R.H. ALLEN, L.P. FRIED, A. CHAKRAVARTI, S.P. STABLER, M.D. FALLIN

J Nutr Health Aging. Author manuscript; available in PMC 2011 Feb 21.

Published in final edited form as: J Nutr Health Aging. 2010 Jan; 14(1): 73–77. doi: 10.1007/s12603-010-0013-1

PMCID:: PMC3042247

Abstract Article PDF–357K

Select item 298946116.

Systematic Characterization of Human Protein Complexes Identifies Chromosome Segregation Proteins

James R.A. Hutchins, Yusuke Toyoda, Björn Hegemann, Ina Poser, Jean-Karim Hériché, Martina M. Sykora, Martina Augsburg, Otto Hudecz, Bettina A. Buschhorn, Jutta Bulkescher, Christian Conrad, David Comartin, Alexander Schleiffer, Mihail Sarov, Andrei Pozniakovsky, Mikolaj Michal Slabicki, Siegfried Schloissnig, Ines Steinmacher, Marit Leuschner, Andrea Ssykor, Steffen Lawo, Laurence Pelletier, Holger Stark, Kim Nasmyth, Jan Ellenberg, Richard Durbin, Frank Buchholz, Karl Mechtler, Anthony A. Hyman, Jan-Michael Peters

Science. Author manuscript; available in PMC 2010 Nov 22.

Published in final edited form as: Science. 2010 Apr 30; 328(5978): 593–599. Published online 2010 Apr 1. doi: 10.1126/science.1181348

PMCID:: PMC2989461

Abstract Article PDF–2.2M

Select item 294516817.

Variation at the NFATC2 Locus Increases the Risk of Thiazolidinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study

Swneke D. Bailey, Changchun Xie, Ron Do, Alexandre Montpetit, Rafael Diaz, Viswanathan Mohan, Bernard Keavney, Salim Yusuf, Hertzel C. Gerstein, James C. Engert, Sonia Anand, on behalf of the DREAM investigators

Diabetes Care. 2010 Oct; 33(10): 2250–2253. Published online 2010 Jul 13. doi: 10.2337/dc10-0452

PMCID:: PMC2945168

Abstract Article PDF–153K

Select item 286478718.

Transcobalamin C776G Genotype Modifies the Association between Vitamin B12 and Homocysteine in Older Hispanics

Marjorie G. Garrod, Lindsay H. Allen, Mary N. Haan, Ralph Green, Joshua W. Miller

Eur J Clin Nutr. Author manuscript; available in PMC 2010 Nov 1.

Published in final edited form as: Eur J Clin Nutr. 2010 May; 64(5): 503–509. Published online 2010 Mar 10. doi: 10.1038/ejcn.2010.20

PMCID:: PMC2864787

Abstract Article PDF–790K

Select item 281034419.

An Integrative Predictive Model of Coronary Artery Calcification in Arteriosclerosis

Michael McGeachie, Rachel L Badovinac Ramoni, Josyf C. Mychaleckyj, Karen L Furie, Jonathan M. Dreyfuss, Yongmei Liu, David Herrington, Xiuqing Guo, João A. Lima, Wendy Post, Jerome I. Rotter, Stephen Rich, Michèle Sale, Marco F. Ramoni

Circulation. Author manuscript; available in PMC 2010 Dec 15.

Published in final edited form as: Circulation. 2009 Dec 15; 120(24): 2448–2454. doi: 10.1161/CIRCULATIONAHA.109.865501

PMCID:: PMC2810344

Abstract Article PDF–448K

Select item 277583220.

Gene-centric Association Signals for Lipids and Apolipoproteins Identified via the HumanCVD BeadChip

Philippa J. Talmud, Fotios Drenos, Sonia Shah, Tina Shah, Jutta Palmen, Claudio Verzilli, Tom R. Gaunt, Jacky Pallas, Ruth Lovering, Kawah Li, Juan Pablo Casas, Reecha Sofat, Meena Kumari, Santiago Rodriguez, Toby Johnson, Stephen J. Newhouse, Anna Dominiczak, Nilesh J. Samani, Mark Caulfield, Peter Sever, Alice Stanton, Denis C. Shields, on behalf of the ASCOT investigators, Sandosh Padmanabhan, Olle Melander, Claire Hastie, Christian Delles, on behalf of the NORDIL investigators, Shah Ebrahim, Michael G. Marmot, George Davey Smith, Debbie A. Lawlor, Patricia B. Munroe, for the BRIGHT Consortium, Ian N. Day, Mika Kivimaki, John Whittaker, Steve E. Humphries, Aroon D. Hingorani

Am J Hum Genet. 2009 Nov 13; 85(5): 628–642. doi: 10.1016/j.ajhg.2009.10.014

PMCID:: PMC2775832

Abstract Article PDF–2.8M

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