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Items: 1 to 20 of 77

1.
Thymine DNA glycosylase combines sliding, hopping, and nucleosome interactions to efficiently search for 5-formylcytosine
Brittani L. Schnable, Matthew A. Schaich, Vera Roginskaya, Liam P. Leary, Tyler M. Weaver, Bret D. Freudenthal, Alexander C. Drohat, Bennett Van Houten
Nat Commun. 2024; 15: 9226. Published online 2024 Oct 25. doi: 10.1038/s41467-024-53497-7
PMCID:
PMC11512004
AbstractArticlePDF–1.7M
2.
Comprehensive analysis of the prognostic value and biological function of TDG in hepatocellular carcinoma
Guoliang Wang, Yinwen Zhou, Bin Yi, Yanli Long, Bo Ma, Yi Zhang
Cell Cycle. 2023; 22(12): 1478–1495. Published online 2023 May 24. doi: 10.1080/15384101.2023.2216501
PMCID:
PMC10281473
AbstractArticlePDF–4.7M
3.
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery
Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili
Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z
PMCID:
PMC9279285
AbstractArticlePDF–2.5M
4.
TDG suppresses the migration and invasion of human colon cancer cells via the DNMT3A/TIMP2 axis
Jiyu Miao, Changan Zhao, Kaijie Tang, Xiaofan Xiong, Fei Wu, Wanjuan Xue, Baojun Duan, Huahua Zhang, Xintao Jing, Wen Li, Ying Sun, Ni Hou, Chen Huang
Int J Biol Sci. 2022; 18(6): 2527–2539. Published online 2022 Mar 21. doi: 10.7150/ijbs.69266
PMCID:
PMC8990457
AbstractArticlePDF–2.6M
5.
TOPORS-mediated RAD51 SUMOylation facilitates homologous recombination repair
Gurusamy Hariharasudhan, Seo-Yeon Jeong, Min-Ji Kim, Sung Mi Jung, Gwanwoo Seo, Ju-Ran Moon, Sumi Lee, In-Youb Chang, Younghoon Kee, Ho Jin You, Jung-Hee Lee
Nucleic Acids Res. 2022 Feb 22; 50(3): 1501–1516. Published online 2022 Jan 21. doi: 10.1093/nar/gkac009
PMCID:
PMC8860612
AbstractArticlePDF–4.5M
6.
Direct and Base Excision Repair-Mediated Regulation of a GC-Rich cis-Element in Response to 5-Formylcytosine and 5-Carboxycytosine
Nadine Müller, Eveliina Ponkkonen, Thomas Carell, Andriy Khobta
Int J Mol Sci. 2021 Oct; 22(20): 11025. Published online 2021 Oct 13. doi: 10.3390/ijms222011025
PMCID:
PMC8539351
AbstractArticlePDF–2.4M
7.
Reversible chromatin condensation by the DNA repair and demethylation factor thymine DNA glycosylase
Charles E Deckard, III, Jonathan T Sczepanski
Nucleic Acids Res. 2021 Mar 18; 49(5): 2450–2459. Published online 2021 Feb 8. doi: 10.1093/nar/gkab040
PMCID:
PMC7969020
AbstractArticlePDF–1.8M
8.
Genetic Screens Reveal FEN1 and APEX2 as BRCA2 Synthetic Lethal Targets
Kristen Mengwasser, Richard Adeyemi, Yumei Leng, Mei Yuk Choi, Connor Clairmont, Alan D’Andrea, Stephen J. Elledge
Mol Cell. Author manuscript; available in PMC 2019 Dec 4.
Published in final edited form as: Mol Cell. 2019 Mar 7; 73(5): 885–899.e6. Published online 2019 Jan 24. doi: 10.1016/j.molcel.2018.12.008
PMCID:
PMC6892393
AbstractArticlePDF–1.7M
9.
lncRNA H19 contributes to oxidative damage repair in the early age‐related cataract by regulating miR‐29a/TDG axis
Tianyu Cheng, Mudong Xu, Bai Qin, Jian Wu, Yuanyuan Tu, Lihua Kang, Yong Wang, Huaijin Guan
J Cell Mol Med. 2019 Sep; 23(9): 6131–6139. Published online 2019 Jul 7. doi: 10.1111/jcmm.14489
PMCID:
PMC6714223
AbstractArticlePDF–1.4M
10.
Thymine DNA glycosylase as a novel target for melanoma
Pietro Mancuso, Rossella Tricarico, Vikram Bhattacharjee, Laura Cosentino, Yuwaraj Kadariya, Jaroslav Jelinek, Emmanuelle Nicolas, Margret Einarson, Neil Beeharry, Karthik Devarajan, Richard A. Katz, Dorjbal G. Dorjsuren, Hongmao Sun, Anton Simeonov, Antonio Giordano, Joseph R. Testa, Guillaume Davidson, Irwin Davidson, Lionel Larue, Robert W. Sobol, Timothy J. Yen, Alfonso Bellacosa
Oncogene. 2019; 38(19): 3710–3728. Published online 2019 Jan 23. doi: 10.1038/s41388-018-0640-2
Correction in:
Oncogene. 2022 May 3
PMCID:
PMC6563616
AbstractArticlePDF–5.9M
11.
Effect of the thymine‐DNA glycosylase rs4135050 variant on Saudi smoker population
Mikhlid Almutairi, Abdullah Mohammad Alhadeq, Rafa Almeer, Mohammed Almutairi, Mohammed Alzahrani, Abdelhabib Semlali
Mol Genet Genomic Med. 2019 Apr; 7(4): e00590. Published online 2019 Feb 18. doi: 10.1002/mgg3.590
PMCID:
PMC6465727
AbstractArticlePDF–831K
12.
Defining the impact of sumoylation on substrate binding and catalysis by thymine DNA glycosylase
Christopher T Coey, Alexander C Drohat
Nucleic Acids Res. 2018 Jun 1; 46(10): 5159–5170. Published online 2018 Apr 12. doi: 10.1093/nar/gky278
PMCID:
PMC6007377
AbstractArticlePDF–2.2M
13.
Dynamics of the excised base release in thymine DNA glycosylase during DNA repair process
Lin-Tai Da, Yi Shi, Guodong Ning, Jin Yu
Nucleic Acids Res. 2018 Jan 25; 46(2): 568–581. Published online 2017 Dec 14. doi: 10.1093/nar/gkx1261
PMCID:
PMC5778594
AbstractArticlePDF–3.8M
14.
RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination
Nila Roy Choudhury, Gregory Heikel, Maryia Trubitsyna, Peter Kubik, Jakub Stanislaw Nowak, Shaun Webb, Sander Granneman, Christos Spanos, Juri Rappsilber, Alfredo Castello, Gracjan Michlewski
BMC Biol. 2017; 15: 105. Published online 2017 Nov 8. doi: 10.1186/s12915-017-0444-9
PMCID:
PMC5678581
AbstractArticlePDF–3.2M
15.
Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism
Giulia Antoniali, Fabrizio Serra, Lisa Lirussi, Mikiei Tanaka, Chiara D’Ambrosio, Shiheng Zhang, Slobodanka Radovic, Emiliano Dalla, Yari Ciani, Andrea Scaloni, Mengxia Li, Silvano Piazza, Gianluca Tell
Nat Commun. 2017; 8: 797. Published online 2017 Oct 6. doi: 10.1038/s41467-017-00842-8
PMCID:
PMC5630600
AbstractArticlePDF–2.3M
16.
TET2- and TDG-mediated changes are required for the acquisition of distinct histone modifications in divergent terminal differentiation of myeloid cells
Antonio Garcia-Gomez, Tianlu Li, Martin Kerick, Francesc Català-Moll, Natalia R. Comet, Javier Rodríguez-Ubreva, Lorenzo de la Rica, Miguel R. Branco, Javier Martín, Esteban Ballestar
Nucleic Acids Res. 2017 Sep 29; 45(17): 10002–10017. Published online 2017 Jul 29. doi: 10.1093/nar/gkx666
PMCID:
PMC5622316
AbstractArticlePDF–2.3M
17.
Nei-like 1 (NEIL1) excises 5-carboxylcytosine directly and stimulates TDG-mediated 5-formyl and 5-carboxylcytosine excision
Anton Slyvka, Karolina Mierzejewska, Matthias Bochtler
Sci Rep. 2017; 7: 9001. Published online 2017 Aug 21. doi: 10.1038/s41598-017-07458-4
PMCID:
PMC5566547
AbstractArticlePDF–1.7M
18.
Linking functions: an additional role for an intrinsically disordered linker domain in the transcriptional coactivator CBP
Sara Contreras-Martos, Alessandro Piai, Simone Kosol, Mihaly Varadi, Angela Bekesi, Pierre Lebrun, Alexander N. Volkov, Kris Gevaert, Roberta Pierattelli, Isabella C. Felli, Peter Tompa
Sci Rep. 2017; 7: 4676. Published online 2017 Jul 5. doi: 10.1038/s41598-017-04611-x
PMCID:
PMC5498717
AbstractArticlePDF–3.7M
19.
HSP90 shapes the consequences of human genetic variation
Georgios I. Karras, Song Yi, Nidhi Sahni, Máté Fischer, Jenny Xie, Marc Vidal, Alan D. D'Andrea, Luke Whitesell, Susan Lindquist
Cell. Author manuscript; available in PMC 2018 Feb 23.
Published in final edited form as: Cell. 2017 Feb 23; 168(5): 856–866.e12. Published online 2017 Feb 16. doi: 10.1016/j.cell.2017.01.023
PMCID:
PMC5325763
AbstractArticlePDF–2.4M
20.
Structural basis for excision of 5-formylcytosine by thymine DNA glycosylase
Lakshmi S. Pidugu, Joshua W. Flowers, Christopher T. Coey, Edwin Pozharski, Marc M. Greenberg, Alexander C. Drohat
Biochemistry. Author manuscript; available in PMC 2017 Nov 15.
Published in final edited form as: Biochemistry. 2016 Nov 15; 55(45): 6205–6208. Published online 2016 Nov 2. doi: 10.1021/acs.biochem.6b00982
PMCID:
PMC5148694
AbstractArticlePDF–769K

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