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Select item 110896831.

Estetrol/GPER/SERPINB2 transduction signaling inhibits the motility of triple-negative breast cancer cells

Francesca Cirillo, Asia Spinelli, Marianna Talia, Domenica Scordamaglia, Maria Francesca Santolla, Fedora Grande, Bruno Rizzuti, Marcello Maggiolini, Céline Gérard, Rosamaria Lappano

J Transl Med. 2024; 22: 450. Published online 2024 May 13. doi: 10.1186/s12967-024-05269-6

PMCID:: PMC11089683

Abstract Article PDF–8.7M

Select item 97384372.

SERPINB2, an Early Responsive Gene to Epigallocatechin Gallate, Inhibits Migration and Promotes Apoptosis in Esophageal Cancer Cells

Zikai Chen, Yifu Wei, Yuzhong Zheng, Hui Zhu, Qian Teng, Xianglan Lin, Fengnian Wu, Fei Zhou

Cells. 2022 Dec; 11(23): 3852. Published online 2022 Nov 30. doi: 10.3390/cells11233852

PMCID:: PMC9738437

Abstract Article PDF–8.3M

Select item 95699553.

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation

Yulemi Gonzalez Quesada, Luc DesGroseillers

Int J Mol Sci. 2022 Oct; 23(19): 11588. Published online 2022 Sep 30. doi: 10.3390/ijms231911588

PMCID:: PMC9569955

Abstract Article PDF–2.1M

Select item 94754534.

The N⁶-methyladenosine-mediated lncRNA WEE2-AS1 promotes glioblastoma progression by stabilizing RPN2

Boyan Li, Rongrong Zhao, Wei Qiu, Ziwen Pan, Shulin Zhao, Yanhua Qi, Jiawei Qiu, Shouji Zhang, Qindong Guo, Yang Fan, Hao Xu, Ming Li, Gang Li, Hao Xue

Theranostics. 2022; 12(14): 6363–6379. Published online 2022 Aug 29. doi: 10.7150/thno.74600

PMCID:: PMC9475453

Abstract Article PDF–4.4M

Select item 92792855.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 89979076.

A Novel Role for Plasminogen Activator Inhibitor Type-2 as a Hypochlorite-Resistant Serine Protease Inhibitor and Holdase Chaperone

Jordan H. Cater, Noralyn B. Mañucat-Tan, Demi K. Georgiou, Guomao Zhao, Irina A. Buhimschi, Amy R. Wyatt, Marie Ranson

Cells. 2022 Apr; 11(7): 1152. Published online 2022 Mar 29. doi: 10.3390/cells11071152

PMCID:: PMC8997907

Abstract Article PDF–4.0M

Select item 85664737.

Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma

Tatenda Mahlokozera, Bhuvic Patel, Hao Chen, Patrick Desouza, Xuan Qu, Diane D. Mao, Daniel Hafez, Wei Yang, Rukayat Taiwo, Mounica Paturu, Afshin Salehi, Amit D. Gujar, Gavin P. Dunn, Nima Mosammaparast, Allegra A. Petti, Hiroko Yano, Albert H. Kim

Nat Commun. 2021; 12: 6321. Published online 2021 Nov 3. doi: 10.1038/s41467-021-26653-6

PMCID:: PMC8566473

Abstract Article PDF–2.7M

Select item 81650308.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 81408419.

HMSC-Derived Exosome Inhibited Th2 Cell Differentiation via Regulating miR-146a-5p/SERPINB2 Pathway

Jing Zhou, Yi Lu, Wei Wu, Yunhai Feng

J Immunol Res. 2021; 2021: 6696525. Published online 2021 May 14. doi: 10.1155/2021/6696525

PMCID:: PMC8140841

Abstract Article PDF–2.1M

Select item 792163710.

HKB99, an allosteric inhibitor of phosphoglycerate mutase 1, suppresses invasive pseudopodia formation and upregulates plasminogen activator inhibitor-2 in erlotinib-resistant non-small cell lung cancer cells

Qian Liang, Wei-ming Gu, Ke Huang, Ming-yu Luo, Jing-hua Zou, Guang-lei Zhuang, Hui-min Lei, Hong-zhuan Chen, Liang Zhu, Lu Zhou, Ying Shen

Acta Pharmacol Sin. 2021 Jan; 42(1): 115–119. Published online 2020 May 13. doi: 10.1038/s41401-020-0399-1

PMCID:: PMC7921637

Abstract Article PDF–1.2M

Select item 779140611.

Deficiency of Plasminogen Activator Inhibitor-2 Results in Accelerated Tumor Growth

Randal J. Westrick, Lisa Payne Røjkjær, Angela Y. Yang, Michael H. Roh, Amy E. Siebert, David Ginsburg

J Thromb Haemost. Author manuscript; available in PMC 2021 Nov 1.

Published in final edited form as: J Thromb Haemost. 2020 Nov; 18(11): 2968–2975. Published online 2020 Oct 1. doi: 10.1111/jth.15054

PMCID:: PMC7791406

Abstract Article PDF–1.3M

Select item 764586312.

N‐Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS‐CoV‐2 Main Protease

Tomas Koudelka, Juliane Boger, Alessandra Henkel, Robert Schönherr, Stefanie Krantz, Sabine Fuchs, Estefanía Rodríguez, Lars Redecke, Andreas Tholey

Proteomics. 2021 Jan; 21(2): 2000246. Published online 2020 Nov 17. doi: 10.1002/pmic.202000246

PMCID:: PMC7645863

Abstract Article PDF–497K

Select item 735220213.

An Integrative Synthetic Biology Approach to Interrogating Cellular Ubiquitin and Ufm Signaling

Chuanyin Li, Tianting Han, Rong Guo, Peng Chen, Chao Peng, Gali Prag, Ronggui Hu

Int J Mol Sci. 2020 Jun; 21(12): 4231. Published online 2020 Jun 14. doi: 10.3390/ijms21124231

PMCID:: PMC7352202

Abstract Article PDF–1.5M

Select item 661266514.

An Endogenous Anti-aging Factor, Sonic Hedgehog, Suppresses Endometrial Stem Cell Aging through SERPINB2

Ara Cho, Se-Ra Park, Soo-Rim Kim, Seungyoon Nam, Soyi Lim, Chan Hum Park, Hwa-Yong Lee, In-Sun Hong

Mol Ther. 2019 Jul 3; 27(7): 1286–1298. Published online 2019 Apr 27. doi: 10.1016/j.ymthe.2019.04.019

PMCID:: PMC6612665

Abstract Article PDF–4.0M

Select item 601043215.

SERPINB2 is a novel indicator of stem cell toxicity

Na-Hee Lee, Ara Cho, Se-Ra Park, Jin Woo Lee, Park Sung Taek, Chan Hum Park, Yoon-Hyeong Choi, Soyi Lim, Min-Kwan Baek, Dong Young Kim, Mirim Jin, Hwa-Yong Lee, In-Sun Hong

Cell Death Dis. 2018 Jul; 9(7): 724. Published online 2018 Jun 20. doi: 10.1038/s41419-018-0748-x

PMCID:: PMC6010432

Abstract Article PDF–2.3M

Select item 577315416.

The microRNA-15a-PAI-2 axis in cholangiocarcinoma-associated fibroblasts promotes migration of cancer cells

Penkhae Utaijaratrasmi, Kulthida Vaeteewoottacharn, Takaaki Tsunematsu, Pranisa Jamjantra, Sopit Wongkham, Chawalit Pairojkul, Narong Khuntikeo, Naozumi Ishimaru, Yongyut Sirivatanauksorn, Ananya Pongpaibul, Peti Thuwajit, Chanitra Thuwajit, Yasusei Kudo

Mol Cancer. 2018; 17: 10. Published online 2018 Jan 18. doi: 10.1186/s12943-018-0760-x

PMCID:: PMC5773154

Abstract Article PDF–4.2M

Select item 558980817.

SERPINB2 is a novel TGFβ-responsive lineage fate determinant of human bone marrow stromal cells

Mona Elsafadi, Muthurangan Manikandan, Muhammad Atteya, Raed Abu Dawud, Sami Almalki, Zahid Ali Kaimkhani, Abdullah Aldahmash, Nehad M. Alajez, Musaad Alfayez, Moustapha Kassem, Amer Mahmood

Sci Rep. 2017; 7: 10797. Published online 2017 Sep 7. doi: 10.1038/s41598-017-10983-x

PMCID:: PMC5589808

Abstract Article PDF–6.7M

Select item 553760618.

SerpinB2 regulates stromal remodelling and local invasion in pancreatic cancer

N L E Harris, C Vennin, J R W Conway, K L Vine, M Pinese, M J Cowley, R F Shearer, M C Lucas, D Herrmann, A H Allam, M Pajic, J P Morton, Australian Pancreatic Cancer Genome Initiative, A V Biankin, M Ranson, P Timpson, D N Saunders

Oncogene. 2017 Jul 27; 36(30): 4288–4298. Published online 2017 Mar 27. doi: 10.1038/onc.2017.63

PMCID:: PMC5537606

Abstract Article PDF–2.9M

Select item 553580619.

SERPINB2 is regulated by dynamic interactions with pause-release proteins and enhancer RNAs

Lihua Shi, Li Song, Kelly Maurer, Zhe Zhang, Kathleen E. Sullivan

Mol Immunol. Author manuscript; available in PMC 2018 Aug 1.

Published in final edited form as: Mol Immunol. 2017 Aug; 88: 20–31. Published online 2017 Jun 1. doi: 10.1016/j.molimm.2017.05.005

PMCID:: PMC5535806

Abstract Article PDF–1.4M

Select item 553161120.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

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