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Select item 111591841.

ESE‐3, an Ets family transcription factor, is up‐regulated in cellular senescence

Makoto Fujikawa, Toyomasa Katagiri, Antonio Tugores, Yusuke Nakamura, Fuyuki Ishikawa

Cancer Sci. 2007 Sep; 98(9): 1468–1475. Published online 2007 Jul 11. doi: 10.1111/j.1349-7006.2007.00543.x

PMCID:: PMC11159184

Abstract Article PDF–549K

Select item 83539212.

Activation of EHF via STAT3 phosphorylation by LMP2A in Epstein‐Barr virus–positive gastric cancer

Wenzhe Li, Atsushi Okabe, Genki Usui, Masaki Fukuyo, Keisuke Matsusaka, Bahityar Rahmutulla, Yasunobu Mano, Takayuki Hoshii, Sayaka Funata, Nobuhiro Hiura, Masashi Fukayama, Patrick Tan, Tetsuo Ushiku, Atsushi Kaneda

Cancer Sci. 2021 Aug; 112(8): 3349–3362. Published online 2021 Jun 13. doi: 10.1111/cas.14978

PMCID:: PMC8353921

Abstract Article PDF–2.9M

Select item 81650303.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 80728154.

EHF enhances malignancy by modulating AKT and MAPK/ERK signaling in non-small cell lung cancer cells

Lei Gao, Tian Yang, Shuo Zhang, Yiqian Liang, Puyu Shi, Hui Ren, Peng Hou, Mingwei Chen

Oncol Rep. 2021 Jun; 45(6): 102. Published online 2021 Apr 15. doi: 10.3892/or.2021.8053

PMCID:: PMC8072815

Abstract Article PDF–1.3M

Select item 77908225.

Loss of EHF facilitates the development of treatment-induced neuroendocrine prostate cancer

Zhi Long, Liang Deng, Chao Li, Qiangrong He, Yao He, Xiheng Hu, Yi Cai, Yu Gan

Cell Death Dis. 2021 Jan; 12(1): 46. Published online 2021 Jan 5. doi: 10.1038/s41419-020-03326-8

PMCID:: PMC7790822

Abstract Article PDF–2.4M

Select item 68157776.

Coordinate regulation of ELF5 and EHF at the chr11p13 CF modifier region

Hannah Swahn, Jey Sabith Ebron, Kay‐Marie Lamar, Shiyi Yin, Jenny L. Kerschner, Monali NandyMazumdar, Candice Coppola, Eric M. Mendenhall, Shih‐Hsing Leir, Ann Harris

J Cell Mol Med. 2019 Nov; 23(11): 7726–7740. Published online 2019 Sep 26. doi: 10.1111/jcmm.14646

PMCID:: PMC6815777

Abstract Article PDF–1.4M

Select item 64005407.

Tumoral EHF predicts the efficacy of anti-PD1 therapy in pancreatic ductal adenocarcinoma

Jing Liu, Wenna Jiang, Kaili Zhao, Hongwei Wang, Tianxing Zhou, Weiwei Bai, Xiuchao Wang, Tiansuo Zhao, Chongbiao Huang, Song Gao, Tai Qin, Wenwen Yu, Bo Yang, Xin Li, Danqi Fu, Wei Tan, Shengyu Yang, He Ren, Jihui Hao

J Exp Med. 2019 Mar 4; 216(3): 656–673. doi: 10.1084/jem.20180749

PMCID:: PMC6400540

Abstract Article PDF–4.5M

Select item 63816328.

A novel miR-365-3p/EHF/keratin 16 axis promotes oral squamous cell carcinoma metastasis, cancer stemness and drug resistance via enhancing β5-integrin/c-met signaling pathway

Wei-Chieh Huang, Te-Hsuan Jang, Shiao-Lin Tung, Tzu-Chen Yen, Shih-Hsuan Chan, Lu-Hai Wang

J Exp Clin Cancer Res. 2019; 38: 89. Published online 2019 Feb 19. doi: 10.1186/s13046-019-1091-5

PMCID:: PMC6381632

Abstract Article PDF–5.6M

Select item 55877319.

Regulatory dynamics of 11p13 suggest a role for EHF in modifying CF lung disease severity

Lindsay R. Stolzenburg, Rui Yang, Jenny L. Kerschner, Sara Fossum, Matthew Xu, Andrew Hoffmann, Kay-Marie Lamar, Sujana Ghosh, Sarah Wachtel, Shih-Hsing Leir, Ann Harris

Nucleic Acids Res. 2017 Sep 6; 45(15): 8773–8784. Published online 2017 May 26. doi: 10.1093/nar/gkx482

PMCID:: PMC5587731

Abstract Article PDF–2.8M

Select item 553161110.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 549522511.

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing

Teng Fei, Yiwen Chen, Tengfei Xiao, Wei Li, Laura Cato, Peng Zhang, Maura B. Cotter, Michaela Bowden, Rosina T. Lis, Shuang G. Zhao, Qiu Wu, Felix Y. Feng, Massimo Loda, Housheng Hansen He, X. Shirley Liu, Myles Brown

Proc Natl Acad Sci U S A. 2017 Jun 27; 114(26): E5207–E5215. Published online 2017 Jun 13. doi: 10.1073/pnas.1617467114

PMCID:: PMC5495225

Abstract Article PDF–1.3M

Select item 549177812.

Ets homologous factor (EHF) has critical roles in epithelial dysfunction in airway disease

Sara L. Fossum, Michael J. Mutolo, Antonio Tugores, Sujana Ghosh, Scott H. Randell, Lisa C. Jones, Shih-Hsing Leir, Ann Harris

J Biol Chem. 2017 Jun 30; 292(26): 10938–10949. Published online 2017 May 1. doi: 10.1074/jbc.M117.775304

PMCID:: PMC5491778

Abstract Article PDF–2.8M

Select item 536354713.

The ETS factor ESE3/EHF represses IL-6 preventing STAT3 activation and expansion of the prostate cancer stem-like compartment

Domenico Albino, Gianluca Civenni, Simona Rossi, Abhishek Mitra, Carlo V. Catapano, Giuseppina M. Carbone

Oncotarget. 2016 Nov 22; 7(47): 76756–76768. Published online 2016 Oct 8. doi: 10.18632/oncotarget.12525

PMCID:: PMC5363547

Abstract Article PDF–5.3M

Select item 531337614.

ESE3 inhibits pancreatic cancer metastasis by upregulating E-cadherin

Tiansuo Zhao, Wenna Jiang, Xiuchao Wang, Hongwei Wang, Chen Zheng, Yang Li, Yan Sun, Chongbiao Huang, Zhi-bo Han, Shengyu Yang, Zhiliang Jia, Keping Xie, He Ren, Jihui Hao

Cancer Res. Author manuscript; available in PMC 2018 Feb 15.

Published in final edited form as: Cancer Res. 2017 Feb 15; 77(4): 874–885. Published online 2016 Dec 6. doi: 10.1158/0008-5472.CAN-16-2170

PMCID:: PMC5313376

Abstract Article PDF–3.3M

Select item 529540515.

Increased expression of EHF contributes to thyroid tumorigenesis through transcriptionally regulating HER2 and HER3

Yanyan Lv, Fang Sui, Jingjing Ma, Xiaojuan Ren, Qi Yang, Yanfang Zhang, Haixia Guan, Bingyin Shi, Peng Hou, Meiju Ji

Oncotarget. 2016 Sep 6; 7(36): 57978–57990. Published online 2016 Aug 9. doi: 10.18632/oncotarget.11154

PMCID:: PMC5295405

Abstract Article PDF–3.5M

Select item 513400116.

Increased expression of EHF via gene amplification contributes to the activation of HER family signaling and associates with poor survival in gastric cancer

Jing Shi, Yiping Qu, Xinru Li, Fang Sui, Demao Yao, Qi Yang, Bingyin Shi, Meiju Ji, Peng Hou

Cell Death Dis. 2016 Oct; 7(10): e2442. Published online 2016 Oct 27. doi: 10.1038/cddis.2016.346

PMCID:: PMC5134001

Abstract Article PDF–4.4M

Select item 461721117.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

Select item 449483118.

Regulation of epithelium-specific Ets-like factors ESE-1 and ESE-3 in airway epithelial cells: potential roles in airway inflammation

Jing Wu, Rongqi Duan, Huibi Cao, Deborah Field, Catherine M Newnham, David R Koehler, Noe Zamel, Melanie A Pritchard, Paul Hertzog, Martin Post, A Keith Tanswell, Jim Hu

Cell Res. Author manuscript; available in PMC 2015 Jul 7.

Published in final edited form as: Cell Res. 2008 Jun; 18(6): 649–663. doi: 10.1038/cr.2008.57

PMCID:: PMC4494831

Abstract Article PDF–1.4M

Select item 442398919.

Abnormal Localization and Tumor Suppressor Function of Epithelial Tissue-Specific Transcription Factor ESE3 in Esophageal Squamous Cell Carcinoma

Li Wang, Jie Xing, Rui Cheng, Ying Shao, Peng Li, Shengtao Zhu, Shutian Zhang

PLoS One. 2015; 10(5): e0126319. Published online 2015 May 7. doi: 10.1371/journal.pone.0126319

PMCID:: PMC4423989

Abstract Article PDF–12M

Select item 415654320.

GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region

Don L. Armstrong, Raphael Zidovetzki, Marta E Alarcón-Riquelme, Betty P Tsao, Lindsey A Criswell, Robert P Kimberly, John B Harley, Kathy L Sivils, Timothy J Vyse, Patrick M. Gaffney, Carl D Langefeld, Chaim O. Jacob

Genes Immun. Author manuscript; available in PMC 2015 Mar 1.

Published in final edited form as: Genes Immun. 2014 Sep; 15(6): 347–354. Published online 2014 May 29. doi: 10.1038/gene.2014.23

PMCID:: PMC4156543

Abstract Article PDF–1.5M

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