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Select item 105658761.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

Select item 99321022.

SVEP1 is an endogenous ligand for the orphan receptor PEAR1

Jared S. Elenbaas, Upasana Pudupakkam, Katrina J. Ashworth, Chul Joo Kang, Ved Patel, Katherine Santana, In-Hyuk Jung, Paul C. Lee, Kendall H. Burks, Junedh M. Amrute, Robert P. Mecham, Carmen M. Halabi, Arturo Alisio, Jorge Di Paola, Nathan O. Stitziel

Nat Commun. 2023; 14: 850. Published online 2023 Feb 15. doi: 10.1038/s41467-023-36486-0

Correction in:: Nat Commun. 2023; 14: 1511.

PMCID:: PMC9932102

Abstract Article PDF–8.9M

Select item 98051293.

The integrin ligand SVEP1 regulates GPCR‐mediated vasoconstriction via integrins α9β1 and α4β1

Gavin E. Morris, Matthew J. Denniff, Elisavet Karamanavi, Sarah A. Andrews, Renata B. Kostogrys, Vasiliki Bountziouka, Maryam Ghaderi‐Najafabadi, Noor Shamkhi, George McConnell, Michael A. Kaiser, Laura Carleton, Christine Schofield, Thorsten Kessler, Richard D. Rainbow, Nilesh J. Samani, Thomas R. Webb

Br J Pharmacol. 2022 Nov; 179(21): 4958–4973. Published online 2022 Aug 2. doi: 10.1111/bph.15921

PMCID:: PMC9805129

Abstract Article PDF–28M

Select item 81092614.

SVEP1 is a human coronary artery disease locus that promotes atherosclerosis

In-Hyuk Jung, Jared S. Elenbaas, Arturo Alisio, Katherine Santana, Erica P. Young, Chul Joo Kang, Puja Kachroo, Kory J. Lavine, Babak Razani, Robert P. Mecham, Nathan O. Stitziel

Sci Transl Med. Author manuscript; available in PMC 2021 Sep 24.

Published in final edited form as: Sci Transl Med. 2021 Mar 24; 13(586): eabe0357. doi: 10.1126/scitranslmed.abe0357

PMCID:: PMC8109261

Abstract Article PDF–2.9M

Select item 76665865.

Functional investigation of the coronary artery disease gene SVEP1

Michael J. Winkler, Philipp Müller, Amin M. Sharifi, Jana Wobst, Hanna Winter, Michal Mokry, Lijiang Ma, Sander W. van der Laan, Shichao Pang, Benedikt Miritsch, Julia Hinterdobler, Julia Werner, Barbara Stiller, Ulrich Güldener, Tom R. Webb, Folkert W. Asselbergs, Johan L. M. Björkegren, Lars Maegdefessel, Heribert Schunkert, Hendrik B. Sager, Thorsten Kessler

Basic Res Cardiol. 2020; 115(6): 67. Published online 2020 Nov 13. doi: 10.1007/s00395-020-00828-6

PMCID:: PMC7666586

Abstract Article PDF–2.5M

Select item 75450806.

SVEP1 as a Genetic Modifier of TEK-Related Primary Congenital Glaucoma

Terri L. Young, Kristina N. Whisenhunt, Jing Jin, Sarah M. LaMartina, Sean M. Martin, Tomokazu Souma, Vachiranee Limviphuvadh, Fatemeh Suri, Emmanuelle Souzeau, Xue Zhang, Yongwook Dan, Evie Anagnos, Susana Carmona, Nicole M. Jody, Nickie Stangel, Emily C. Higuchi, Samuel J. Huang, Owen M. Siggs, Maria José Simões, Brendan M. Lawson, Jacob S. Martin, Elahe Elahi, Mehrnaz Narooie-Nejad, Behzad Fallahi Motlagh, Susan E. Quaggin, Heather D. Potter, Eduardo D. Silva, Jamie E. Craig, Conceição Egas, Reza Maroofian, Sebastian Maurer-Stroh, Yasmin S. Bradfield, Stuart W. Tompson

Invest Ophthalmol Vis Sci. 2020 Oct; 61(12): 6. Published online 2020 Oct 7. doi: 10.1167/iovs.61.12.6

PMCID:: PMC7545080

Abstract Article PDF–7.0M

Select item 72007797.

The novel miR-1269b-regulated protein SVEP1 induces hepatocellular carcinoma proliferation and metastasis likely through the PI3K/Akt pathway

Lu Chen, Dongming Liu, Xianfu Yi, Lisha Qi, Xiangdong Tian, Bo Sun, Qiuping Dong, Zhiqiang Han, Qiang Li, Tianqiang Song, Mingxi Guo, Wei Zhang, Hua Guo, Ti Zhang

Cell Death Dis. 2020 May; 11(5): 320. Published online 2020 May 5. doi: 10.1038/s41419-020-2535-8

PMCID:: PMC7200779

Abstract Article PDF–2.6M

Select item 58269268.

VIRMA mediates preferential m⁶A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation

Yanan Yue, Jun Liu, Xiaolong Cui, Jie Cao, Guanzheng Luo, Zezhou Zhang, Tao Cheng, Minsong Gao, Xiao Shu, Honghui Ma, Fengqin Wang, Xinxia Wang, Bin Shen, Yizhen Wang, Xinhua Feng, Chuan He, Jianzhao Liu

Cell Discov. 2018; 4: 10. Published online 2018 Feb 27. doi: 10.1038/s41421-018-0019-0

PMCID:: PMC5826926

Abstract Article PDF–2.3M

Select item 55433069.

SVEP1 plays a crucial role in epidermal differentiation

L Samuelov, Q Li, R Bochner, N Najor, L Albrecht, N Malchin, T Goldsmith, M Grafi-Cohen, D Vodo, G Fainberg, B Meilik, I Goldberg, E Warshauer, T Rogers, S Edie, A Ishida-Yamamoto, L Burzenski, N Erez, SA Murray, AD Irvine, L Shultz, K Green, J Uitto, E Sprecher, O Sarig

Exp Dermatol. Author manuscript; available in PMC 2018 May 1.

Published in final edited form as: Exp Dermatol. 2017 May; 26(5): 423–430. Published online 2017 Feb 20. doi: 10.1111/exd.13256

PMCID:: PMC5543306

Abstract Article PDF–1.7M

Select item 502208410.

Leveraging electronic health records to study pleiotropic effects on bipolar disorder and medical comorbidities

M L Prieto, E Ryu, G D Jenkins, A Batzler, M M Nassan, A B Cuellar-Barboza, J Pathak, S L McElroy, M A Frye, J M Biernacka

Transl Psychiatry. 2016 Aug; 6(8): e870. Published online 2016 Aug 16. doi: 10.1038/tp.2016.138

PMCID:: PMC5022084

Abstract Article PDF–174K

Select item 485083811.

Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease

Myocardial Infarction Genetics and CARDIoGRAM Exome Consortia Investigators

N Engl J Med. Author manuscript; available in PMC 2016 Sep 24.

Published in final edited form as: N Engl J Med. 2016 Mar 24; 374(12): 1134–1144. Published online 2016 Mar 2. doi: 10.1056/NEJMoa1507652

PMCID:: PMC4850838

Abstract Article PDF–456K

Select item 355872512.

Exploring genome-wide – dietary heme iron intake interactions and the risk of type 2 diabetes

Louis R. Pasquale, Stephanie J. Loomis, Hugues Aschard, Jae H. Kang, Marilyn C. Cornelis, Lu Qi, Peter Kraft, Frank B. Hu

Front Genet. 2013; 4: 7. Published online 2013 Jan 30. doi: 10.3389/fgene.2013.00007

PMCID:: PMC3558725

Abstract Article PDF–274K

Select item 340819713.

Polydom/SVEP1 Is a Ligand for Integrin α9β1

Ryoko Sato-Nishiuchi, Itsuko Nakano, Akio Ozawa, Yuya Sato, Makiko Takeichi, Daiji Kiyozumi, Kiyoshi Yamazaki, Teruo Yasunaga, Sugiko Futaki, Kiyotoshi Sekiguchi

J Biol Chem. 2012 Jul 20; 287(30): 25615–25630. Published online 2012 May 31. doi: 10.1074/jbc.M112.355016

PMCID:: PMC3408197

Abstract Article PDF–5.3M

Select item 334049914.

Genome-wide association study of lung function decline in adults with and without asthma

Medea Imboden, Emmanuelle Bouzigon, Ivan Curjuric, Adaikalavan Ramasamy, Ashish Kumar, Dana B Hancock, Jemma B Wilk, Judith M Vonk, Gian A Thun, Valerie Siroux, Rachel Nadif, Florent Monier, Juan R Gonzalez, Matthias Wjst, Joachim Heinrich, Laura R Loehr, Nora Franceschini, Kari E North, Janine Altmüller, Gerard H. Koppelman, Stefano Guerra, Florian Kronenberg, Mark Lathrop, Miriam F Moffatt, George T O’Connor, David P Strachan, Dirkje S Postma, Stephanie J London, Christian Schindler, Manolis Kogevinas, Francine Kauffmann, Debbie L Jarvis, Florence Demenais, Nicole M Probst-Hensch

J Allergy Clin Immunol. Author manuscript; available in PMC 2013 May 1.

Published in final edited form as: J Allergy Clin Immunol. 2012 May; 129(5): 1218–1228. Published online 2012 Mar 16. doi: 10.1016/j.jaci.2012.01.074

PMCID:: PMC3340499

Abstract Article PDF–1.1M

Select item 317805915.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 298460916.

Joint influence of small-effect genetic variants on human longevity

Anatoliy I. Yashin, Deqing Wu, Konstantin G. Arbeev, Svetlana V. Ukraintseva

Aging (Albany NY) 2010 Sep; 2(9): 612–620. Published online 2010 Aug 26. doi: 10.18632/aging.100191

PMCID:: PMC2984609

Abstract Article PDF–1.3M

Select item 289646417.

Personalized Smoking Cessation: Interactions between Nicotine Dose, Dependence and Quit-Success Genotype Score

Jed E Rose, Frédérique M Behm, Tomas Drgon, Catherine Johnson, George R Uhl

Mol Med. 2010 Jul-Aug; 16(7-8): 247–253. Published online 2010 Mar 17. doi: 10.2119/molmed.2009.00159

Correction in:: Mol Med. 2012; 18(1): 729.

PMCID:: PMC2896464

Abstract Article PDF–2.4M

Select item 287109518.

Fine mapping of the 9q31 Hirschsprung’s disease locus

C. S. Tang, Y. Sribudiani, X. P. Miao, A. R. de Vries, G. Burzynski, M. T. So, Y. Y. Leon, B. H. Yip, J. Osinga, K. J. W. S. Hui, J. B. G. M. Verheij, S. S. Cherny, P. K. H. Tam, P. C. Sham, R. M. W. Hofstra, M. M. Garcia-Barceló

Hum Genet. 2010; 127(6): 675–683. Published online 2010 Apr 2. doi: 10.1007/s00439-010-0813-8

PMCID:: PMC2871095

Abstract Article PDF–365K

Select item 270378019.

Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder

Manuel A R Ferreira, Michael C O’Donovan, Yan A Meng, Ian R Jones, Douglas M Ruderfer, Lisa Jones, Jinbo Fan, George Kirov, Roy H Perlis, Elaine K Green, Jordan W Smoller, Detelina Grozeva, Jennifer Stone, Ivan Nikolov, Kimberly Chambert, Marian L Hamshere, Vishwajit L Nimgaonkar, Valentina Moskvina, Michael E Thase, Sian Caesar, Gary S Sachs, Jennifer Franklin, Katherine Gordon-Smith, Kristin G Ardlie, Stacey B Gabriel, Christine Fraser, Brendan Blumenstiel, Matthew Defelice, Gerome Breen, Michael Gill, Derek W Morris, Amanda Elkin, Walter J Muir, Kevin A McGhee, Richard Williamson, Donald J MacIntyre, Alan W MacLean, David St Clair, Michelle Robinson, Margaret Van Beck, Ana C P Pereira, Radhika Kandaswamy, Andrew McQuillin, David A Collier, Nicholas J Bass, Allan H Young, Jacob Lawrence, I Nicol Ferrier, Adebayo Anjorin, Anne Farmer, David Curtis, Edward M Scolnick, Peter McGuffin, Mark J Daly, Aiden P Corvin, Peter A Holmans, Douglas H Blackwood, Wellcome Trust Case Control Consortium, Hugh M Gurling, Michael J Owen, Shaun M Purcell, Pamela Sklar, Nick Craddock

Nat Genet. Author manuscript; available in PMC 2009 Jun 30.

Published in final edited form as: Nat Genet. 2008 Sep; 40(9): 1056–1058. doi: 10.1038/ng.209

PMCID:: PMC2703780

Abstract Article PDF–557K

Select item 122143120.

Polydom: a secreted protein with pentraxin, complement control protein, epidermal growth factor and von Willebrand factor A domains.

D Gilgès, M A Vinit, I Callebaut, L Coulombel, V Cacheux, P H Romeo, I Vigon

Biochem J. 2000 Nov 15; 352(Pt 1): 49–59.

PMCID:: PMC1221431

Summary PDF–671K

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