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Select item 115122251.

STING Orchestrates EV-D68 Replication and Immunometabolism within Viral-Induced Replication Organelles

Kathy Triantafilou, Barbara Szomolay, Mark William Shepherd, Joshi Ramanjulu, Martha Triantafilou

Viruses. 2024 Oct; 16(10): 1541. Published online 2024 Sep 29. doi: 10.3390/v16101541

PMCID:: PMC11512225

Abstract Article PDF–1.2M

Select item 114410742.

FMT rescues mice from DSS-induced colitis in a STING-dependent manner

Dan Pu, Yao Yao, Chuan Zhou, Ruixian Liu, Zhihong Wang, Yan Liu, Dandan Wang, Binbin Wang, Yaohe Wang, Zhanju Liu, Zhe Zhang, Baisui Feng

Gut Microbes. 2024; 16(1): 2397879. Published online 2024 Sep 26. doi: 10.1080/19490976.2024.2397879

PMCID:: PMC11441074

Abstract Article PDF–36M

Select item 114252213.

Inactivated cGAS‐STING Signaling Facilitates Endocrine Resistance by Forming a Positive Feedback Loop with AKT Kinase in ER+HER2– Breast Cancer

Kai‐Ming Zhang, De‐Chang Zhao, Ze‐Yu Li, Yan Wang, Jian‐Nan Liu, Tian Du, Ling Zhou, Yu‐Hong Chen, Qi‐Chao Yu, Qing‐Shan Chen, Rui‐Zhao Cai, Zi‐Xuan Zhao, Jia‐Lu Shan, Bing‐Xin Hu, Hai‐Liang Zhang, Gong‐Kan Feng, Xiao‐Feng Zhu, Jun Tang, Rong Deng

Adv Sci (Weinh) 2024 Sep; 11(35): 2403592. Published online 2024 Jul 18. doi: 10.1002/advs.202403592

PMCID:: PMC11425221

Abstract Article PDF–21M

Select item 114252014.

Activation of the cGAS‐STING‐IRF3 Axis by Type I and II Interferons Contributes to Host Defense

Zhen Tong, Jia‐Peng Zou, Su‐Yun Wang, Wei‐Wei Luo, Yan‐Yi Wang

Adv Sci (Weinh) 2024 Sep; 11(35): 2308890. Published online 2024 Jul 14. doi: 10.1002/advs.202308890

PMCID:: PMC11425201

Abstract Article PDF–5.4M

Select item 114185785.

VPS13C and STING expression in neuropsychiatric systemic lupus erythematosus: unveiling an unbreached territory

Amany M Ebaid, Mohammad A Zakaria, Enas M Mekkawy, Rania S Nageeb, Rabab M Elfwakhry, Dina A Seleem, Marwa A Shabana, Marwa M Esawy

Lupus Sci Med. 2024; 11(2): e001271. Published online 2024 Sep 20. doi: 10.1136/lupus-2024-001271

PMCID:: PMC11418578

Abstract Article PDF–882K

Select item 113798676.

High levels of tumor cell-intrinsic STING signaling are associated with increased infiltration of CD8⁺ T cells in dMMR/MSI-H gastric cancer

Ryo Kanoda, Shotaro Nakajima, Satoshi Fukai, Motonobu Saito, Katsuharu Saito, Hiroya Suzuki, Tomohiro Kikuchi, Azuma Nirei, Hirokazu Okayama, Kosaku Mimura, Hiroyuki Hanayama, Wataru Sakamoto, Tomoyuki Momma, Zenichiro Saze, Koji Kono

Sci Rep. 2024; 14: 20859. Published online 2024 Sep 6. doi: 10.1038/s41598-024-71974-3

PMCID:: PMC11379867

Abstract Article PDF–1.7M

Select item 113488157.

The crucial roles and research advances of cGAS‑STING pathway in liver diseases

Xiaoqian Zhang, Bin He, Juan Lu, Qiongling Bao, Jie Wang, Yida Yang

Ann Med. 2024; 56(1): 2394588. Published online 2024 Aug 25. doi: 10.1080/07853890.2024.2394588

PMCID:: PMC11348815

Abstract Article PDF–1.4M

Select item 113467938.

Hsa-miR-181a-2-3p inhibits the oncogenicity of colon cancer by directly targeting STING

Bowei Liu, Kai Lu, Lijie Yuan, Xiaofang Li, Ling Lan, Shuangyin Han

Aging (Albany NY) 2024 Aug 15; 16(15): 11729–11743. Published online 2024 Aug 9. doi: 10.18632/aging.206059

PMCID:: PMC11346793

Abstract Article PDF–1.1M

Select item 113037089.

53BP1 loss elicits cGAS-STING-dependent antitumor immunity in ovarian and pancreatic cancer

Yajie Sun, Jeffrey Patterson-Fortin, Sen Han, Zhe Li, Zuzanna Nowicka, Yuna Hirohashi, Susan Kilgas, Jae Kyo Yi, Alexander Spektor, Wojciech Fendler, Panagiotis A. Konstantinopoulos, Dipanjan Chowdhury

Nat Commun. 2024; 15: 6676. Published online 2024 Aug 6. doi: 10.1038/s41467-024-50999-2

PMCID:: PMC11303708

Abstract Article PDF–7.1M

Select item 1130323010.

The effects of cGAS-STING inhibition in liver disease, kidney disease, and cellular senescence

Ling Wang, Zhengwei Zhang, Haichao Zhang, Minmin Zhou, Cheng Huang, Wenjiang Xia, Jun Li, Hongmei You

Front Immunol. 2024; 15: 1346446. Published online 2024 Jul 24. doi: 10.3389/fimmu.2024.1346446

PMCID:: PMC11303230

Abstract Article PDF–1.2M

Select item 1130308311.

Intestinal epithelial damage-derived mtDNA activates STING-IL12 axis in dendritic cells to promote colitis

Yajie Cai, Shuo Li, Yang Yang, Shuni Duan, Guifang Fan, Jinzhao Bai, Qi Zheng, Yiqing Gu, Xiaojiaoyang Li, Runping Liu

Theranostics. 2024; 14(11): 4393–4410. Published online 2024 Jul 16. doi: 10.7150/thno.96184

PMCID:: PMC11303083

Abstract Article PDF–12M

Select item 1126043512.

Human STING is a proton channel

Bingxu Liu, Rebecca J. Carlson, Ivan S. Pires, Matteo Gentili, Ellie Feng, Quentin Hellier, Marc A. Schwartz, Paul C. Blainey, Darrell J. Irvine, Nir Hacohen

Science. Author manuscript; available in PMC 2024 Jul 21.

Published in final edited form as: Science. 2023 Aug 4; 381(6657): 508–514. Published online 2023 Aug 3. doi: 10.1126/science.adf8974

PMCID:: PMC11260435

Abstract Article PDF–1.4M

Select item 1120947413.

cGAS-STING-TBK1 Signaling Promotes Valproic Acid-Responsive Human Cytomegalovirus Immediate-Early Transcription during Infection of Incompletely Differentiated Myeloid Cells

Emily R. Albright, Robert F. Kalejta

Viruses. 2024 Jun; 16(6): 877. Published online 2024 May 30. doi: 10.3390/v16060877

PMCID:: PMC11209474

Abstract Article PDF–2.7M

Select item 1109232714.

The role of HPV11 E7 in modulating STING-dependent interferon β response in recurrent respiratory papillomatosis

Lijuan Chen, Huiying Hu, Yufei Pan, Yuanyuan Lu, Mengyuan Zhao, Yun Zhao, Lixin Wang, Kai Liu, Zhenkun Yu

J Virol. 2024 May; 98(5): e01925-23. Published online 2024 Apr 16. doi: 10.1128/jvi.01925-23

PMCID:: PMC11092327

Abstract Article PDF–2.9M

Select item 1100538815.

Tracing the STING exocytosis pathway during herpes viruses infection

Christos Dogrammatzis, Rabina Saud, Hope Waisner, Sarah Lasnier, Sreenath Muraleedharan Suma, Brandon Grieshaber, Maria Kalamvoki

mBio. 2024 Apr; 15(4): e00373-24. Published online 2024 Mar 12. doi: 10.1128/mbio.00373-24

PMCID:: PMC11005388

Abstract Article PDF–4.0M

Select item 1099238716.

Role of the cGAS-STING pathway in regulating the tumor-immune microenvironment in dMMR/MSI colorectal cancer

Akinao Kaneta, Shotaro Nakajima, Hirokazu Okayama, Takuro Matsumoto, Katsuharu Saito, Tomohiro Kikuchi, Eisei Endo, Misato Ito, Kosaku Mimura, Yasuyuki Kanke, Motonobu Saito, Zenichiro Saze, Shotaro Fujita, Wataru Sakamoto, Hisashi Onozawa, Tomoyuki Momma, Shinji Ohki, Koji Kono

Cancer Immunol Immunother. 2022 Nov; 71(11): 2765–2776. Published online 2022 Apr 16. doi: 10.1007/s00262-022-03200-w

PMCID:: PMC10992387

Abstract Article PDF–4.9M

Select item 1095662317.

STING is significantly increased in high-grade glioma with high risk of recurrence

Meishi Zhong, Manmei Long, Chenjie Han, Saiyan Ji, Qingyuan Yang

Oncoimmunology. 2024; 13(1): 2327682. Published online 2024 Mar 20. doi: 10.1080/2162402X.2024.2327682

PMCID:: PMC10956623

Abstract Article PDF–6.3M

Select item 1093776218.

Neuronal STING activation in amyotrophic lateral sclerosis and frontotemporal dementia

Christine Marques, Aaron Held, Katherine Dorfman, Joon Sung, Catherine Song, Amey S. Kavuturu, Corey Aguilar, Tommaso Russo, Derek H. Oakley, Mark W. Albers, Bradley T. Hyman, Leonard Petrucelli, Clotilde Lagier-Tourenne, Brian J. Wainger

Acta Neuropathol. 2024; 147(1): 56. Published online 2024 Mar 13. doi: 10.1007/s00401-024-02688-z