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Items: 1 to 20 of 22

1.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
2.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
3.
Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei
Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck
Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924
PMCID:
PMC6166682
AbstractArticlePDF–3.8M
4.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
5.
Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing
Teng Fei, Yiwen Chen, Tengfei Xiao, Wei Li, Laura Cato, Peng Zhang, Maura B. Cotter, Michaela Bowden, Rosina T. Lis, Shuang G. Zhao, Qiu Wu, Felix Y. Feng, Massimo Loda, Housheng Hansen He, X. Shirley Liu, Myles Brown
Proc Natl Acad Sci U S A. 2017 Jun 27; 114(26): E5207–E5215. Published online 2017 Jun 13. doi: 10.1073/pnas.1617467114
PMCID:
PMC5495225
AbstractArticlePDF–1.3M
6.
The BioPlex Network: A Systematic Exploration of the Human Interactome
Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2016 Jul 16.
Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043
PMCID:
PMC4617211
AbstractArticlePDF–2.2M
7.
A proteome-scale map of the human interactome network
Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal
Cell. Author manuscript; available in PMC 2015 Nov 20.
Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050
PMCID:
PMC4266588
AbstractArticlePDF–3.1M
8.
Genome-Wide Association Identifies Regulatory Loci Associated with Distinct Local Histogram Emphysema Patterns
Peter J. Castaldi, Michael H. Cho, Raúl San José Estépar, Merry-Lynn N. McDonald, Nan Laird, Terri H. Beaty, George Washko, James D. Crapo, Edwin K. Silverman
Am J Respir Crit Care Med. 2014 Aug 15; 190(4): 399–409. Published online 2014 Aug 15. doi: 10.1164/rccm.201403-0569OC
PMCID:
PMC4214129
AbstractArticlePDF–1.2M
9.
Genome-Wide Association Studies Identify CHRNA5/3 and HTR4 in the Development of Airflow Obstruction
Jemma B. Wilk, Nick R. G. Shrine, Laura R. Loehr, Jing Hua Zhao, Ani Manichaikul, Lorna M. Lopez, Albert Vernon Smith, Susan R. Heckbert, Joanna Smolonska, Wenbo Tang, Daan W. Loth, Ivan Curjuric, Jennie Hui, Michael H. Cho, Jeanne C. Latourelle, Amanda P. Henry, Melinda Aldrich, Per Bakke, Terri H. Beaty, Amy R. Bentley, Ingrid B. Borecki, Guy G. Brusselle, Kristin M. Burkart, Ting-hsu Chen, David Couper, James D. Crapo, Gail Davies, Josée Dupuis, Nora Franceschini, Amund Gulsvik, Dana B. Hancock, Tamara B. Harris, Albert Hofman, Medea Imboden, Alan L. James, Kay-Tee Khaw, Lies Lahousse, Lenore J. Launer, Augusto Litonjua, Yongmei Liu, Kurt K. Lohman, David A. Lomas, Thomas Lumley, Kristin D. Marciante, Wendy L. McArdle, Bernd Meibohm, Alanna C. Morrison, Arthur W. Musk, Richard H. Myers, Kari E. North, Dirkje S. Postma, Bruce M. Psaty, Stephen S. Rich, Fernando Rivadeneira, Thierry Rochat, Jerome I. Rotter, María Soler Artigas, John M. Starr, André G. Uitterlinden, Nicholas J. Wareham, Cisca Wijmenga, Pieter Zanen, Michael A. Province, Edwin K. Silverman, Ian J. Deary, Lyle J. Palmer, Patricia A. Cassano, Vilmundur Gudnason, R. Graham Barr, Ruth J. F. Loos, David P. Strachan, Stephanie J. London, H. Marike Boezen, Nicole Probst-Hensch, Sina A. Gharib, Ian P. Hall, George T. O’Connor, Martin D. Tobin, Bruno H. Stricker
Am J Respir Crit Care Med. 2012 Oct 1; 186(7): 622–632. Published online 2012 Oct 1. doi: 10.1164/rccm.201202-0366OC
PMCID:
PMC3480517
AbstractArticlePDF–770K
10.
Strong Association between Two Polymorphisms on 15q25.1 and Lung Cancer Risk: A Meta-Analysis
Mingliang Gu, Xiaoqun Dong, Xuezhi Zhang, Xumin Wang, Yue Qi, Jun Yu, Wenquan Niu
PLoS One. 2012; 7(6): e37970. Published online 2012 Jun 6. doi: 10.1371/journal.pone.0037970
PMCID:
PMC3368941
AbstractArticlePDF–242K
11.
Genome-wide association study of smoking behaviors in COPD patients
Mateusz Siedlinski, Michael H. Cho, Per Bakke, Amund Gulsvik, David A. Lomas, Wayne Anderson, Xiangyang Kong, Stephen I. Rennard, Terri H. Beaty, John E. Hokanson, James D. Crapo, Edwin K. Silverman, the COPDGene and ECLIPSE Investigators
Thorax. Author manuscript; available in PMC 2012 Oct 1.
Published in final edited form as: Thorax. 2011 Oct; 66(10): 894–902. Published online 2011 Jun 16. doi: 10.1136/thoraxjnl-2011-200154
PMCID:
PMC3302576
AbstractArticlePDF–1.2M
12.
Molecular Identification of Hydroxylysine Kinase and of Ammoniophospholyases Acting on 5-Phosphohydroxy-l-lysine and Phosphoethanolamine
Maria Veiga-da-Cunha, Farah Hadi, Thomas Balligand, Vincent Stroobant, Emile Van Schaftingen
J Biol Chem. 2012 Mar 2; 287(10): 7246–7255. Published online 2012 Jan 12. doi: 10.1074/jbc.M111.323485
PMCID:
PMC3293546
AbstractArticlePDF–1.0M
13.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
14.
Genetic variations on chromosomes 5p15 and 15q25 and bladder cancer risk: findings from the Los Angeles–Shanghai bladder case–control study
Manuela Gago-Dominguez, Xuejuan Jiang, David V. Conti, Jose Esteban Castelao, Mariana C. Stern, Victoria K. Cortessis, Malcolm C. Pike, Yong-Bing Xiang, Yu-Tang Gao, Jian-Min Yuan, David J. Van Den Berg
Carcinogenesis. 2011 Feb; 32(2): 197–202. Published online 2010 Nov 15. doi: 10.1093/carcin/bgq233
PMCID:
PMC3026841
AbstractArticlePDF–86K
15.
Fine mapping of chromosome 15q25.1 lung cancer susceptibility in African-Americans
Helen M. Hansen, Yuanyuan Xiao, Terri Rice, Paige M. Bracci, Margaret R. Wrensch, Jennette D. Sison, Jeffery S. Chang, Ivan V. Smirnov, Joseph Patoka, Michael F. Seldin, Charles P. Quesenberry, Karl T. Kelsey, John K. Wiencke
Hum Mol Genet. 2010 Sep 15; 19(18): 3652–3661. Published online 2010 Jun 29. doi: 10.1093/hmg/ddq268
PMCID:
PMC2928127
AbstractArticlePDF–215K
16.
Nicotinic Acetylcholine Receptor Region on Chromosome 15q25 and Lung Cancer Risk Among African Americans: A Case–Control Study
Christopher I. Amos, Ivan P. Gorlov, Qiong Dong, Xifeng Wu, Huifeng Zhang, Emily Y. Lu, Paul Scheet, Anthony J. Greisinger, Gordon B. Mills, Margaret R. Spitz
J Natl Cancer Inst. 2010 Aug 4; 102(15): 1199–1205. doi: 10.1093/jnci/djq232
PMCID:
PMC2914761
AbstractArticlePDF–773K
17.
Replication of Lung Cancer Susceptibility Loci at Chromosomes 15q25, 5p15, and 6p21: A Pooled Analysis From the International Lung Cancer Consortium
Therese Truong, Rayjean J. Hung, Christopher I. Amos, Xifeng Wu, Heike Bickeböller, Albert Rosenberger, Wiebke Sauter, Thomas Illig, H.-Erich Wichmann, Angela Risch, Hendrik Dienemann, Rudolph Kaaks, Ping Yang, Ruoxiang Jiang, John K. Wiencke, Margaret Wrensch, Helen Hansen, Karl T. Kelsey, Keitaro Matsuo, Kazuo Tajima, Ann G. Schwartz, Angie Wenzlaff, Adeline Seow, Chen Ying, Andrea Staratschek-Jox, Peter Nürnberg, Erich Stoelben, Jürgen Wolf, Philip Lazarus, Joshua E. Muscat, Carla J. Gallagher, Shanbeh Zienolddiny, Aage Haugen, Henricus F. M. van der Heijden, Lambertus A. Kiemeney, Dolores Isla, Jose Ignacio Mayordomo, Thorunn Rafnar, Kari Stefansson, Zuo-Feng Zhang, Shen-Chih Chang, Jin Hee Kim, Yun-Chul Hong, Eric J. Duell, Angeline S. Andrew, Flavio Lejbkowicz, Gad Rennert, Heiko Müller, Hermann Brenner, Loïc Le Marchand, Simone Benhamou, Christine Bouchardy, M. Dawn Teare, Xiaoyan Xue, John McLaughlin, Geoffrey Liu, James D. McKay, Paul Brennan, Margaret R. Spitz
J Natl Cancer Inst. 2010 Jul 7; 102(13): 959–971. doi: 10.1093/jnci/djq178
PMCID:
PMC2897877
AbstractArticlePDF–630K
18.
Deciphering the impact of common genetic variation on lung cancer risk: A genome-wide association study
Peter Broderick, Yufei Wang, Jayaram Vijayakrishnan, Athena Matakidou, Margaret R Spitz, Timothy Eisen, Christopher I. Amos, Richard S. Houlston
Cancer Res. Author manuscript; available in PMC 2010 Feb 15.
Published in final edited form as: Cancer Res. 2009 Aug 15; 69(16): 6633–6641. Published online 2009 Aug 4. doi: 10.1158/0008-5472.CAN-09-0680
PMCID:
PMC2754318
AbstractArticlePDF–848K
19.
Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1
Christopher I Amos, Xifeng Wu, Peter Broderick, Ivan P Gorlov, Jian Gu, Timothy Eisen, Qiong Dong, Qing Zhang, Xiangjun Gu, Jayaram Vijayakrishnan, Kate Sullivan, Athena Matakidou, Yufei Wang, Gordon Mills, Kimberly Doheny, Ya-Yu Tsai, Wei Vivien Chen, Sanjay Shete, Margaret R Spitz, Richard S Houlston
Nat Genet. Author manuscript; available in PMC 2009 Jul 21.
Published in final edited form as: Nat Genet. 2008 May; 40(5): 616–622. Published online 2008 Apr 2. doi: 10.1038/ng.109
PMCID:
PMC2713680
AbstractArticlePDF–2.4M
20.
A Genome-Wide Association Study in Chronic Obstructive Pulmonary Disease (COPD): Identification of Two Major Susceptibility Loci
Sreekumar G. Pillai, Dongliang Ge, Guohua Zhu, Xiangyang Kong, Kevin V. Shianna, Anna C. Need, Sheng Feng, Craig P. Hersh, Per Bakke, Amund Gulsvik, Andreas Ruppert, Karin C. Lødrup Carlsen, Allen Roses, Wayne Anderson, ICGN Investigators, Stephen I. Rennard, David A. Lomas, Edwin K. Silverman, David B. Goldstein
PLoS Genet. 2009 Mar; 5(3): e1000421. Published online 2009 Mar 20. doi: 10.1371/journal.pgen.1000421
PMCID:
PMC2650282
AbstractArticlePDF–228K

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