PMC Links for GEO Profiles (Select 13636290) - PMC

Select item 108800721.

YTHDF2-regulated matrilin-3 mitigates post-reperfusion hemorrhagic transformation in ischemic stroke via the PI3K/AKT pathway

Hanze Chen, Siping Guo, Runnan Li, Lihui Yang, Rui Wang, Yasi Jiang, Yonggang Hao

J Neuropathol Exp Neurol. 2024 Mar; 83(3): 194–204. Published online 2024 Jan 16. doi: 10.1093/jnen/nlad102

PMCID:: PMC10880072

Abstract Article PDF–1.6M

Select item 99011132.

Methyltransferase-like 3 aggravates endoplasmic reticulum stress in preeclampsia by targeting TMBIM6 in YTHDF2-dependent manner

Yangyang Chen, Xiaoxia Liu, Lun Li, Xiyang He, Fanghui Zheng, Yang Zhang, Hui Gao, Zhishan Jin, Di Wu, Qianhua Wang, Hui Tao, Yin Zhao, Weifang Liu, Li Zou

Mol Med. 2023; 29: 19. Published online 2023 Feb 6. doi: 10.1186/s10020-023-00604-x

PMCID:: PMC9901113

Abstract Article PDF–15M

Select item 93914613.

METTL3 promotes prostatic hyperplasia by regulating PTEN expression in an m⁶A-YTHDF2-dependent manner

Jiaren Li, Hanyu Yao, Jin Huang, Chao Li, Yichuan Zhang, Ran Xu, Zhenting Wang, Zhi Long, Jin Tang, Long Wang

Cell Death Dis. 2022 Aug; 13(8): 723. Published online 2022 Aug 19. doi: 10.1038/s41419-022-05162-4

PMCID:: PMC9391461

Abstract Article PDF–5.9M

Select item 61704354.

Loss of YTHDF2-mediated m⁶A-dependent mRNA clearance facilitates hematopoietic stem cell regeneration

Hu Wang, Hongna Zuo, Jin Liu, Fei Wen, Yawei Gao, Xudong Zhu, Bo Liu, Feng Xiao, Wengong Wang, Gang Huang, Bin Shen, Zhenyu Ju

Cell Res. 2018 Oct; 28(10): 1035–1038. Published online 2018 Aug 27. doi: 10.1038/s41422-018-0082-y

PMCID:: PMC6170435

Article PDF–904K

Select item 61234985.

Suppression of m⁶A reader Ythdf2 promotes hematopoietic stem cell expansion

Zhenrui Li, Pengxu Qian, Wanqing Shao, Hailing Shi, Xi C. He, Madelaine Gogol, Zulin Yu, Yongfu Wang, Meijie Qi, Yunfei Zhu, John M. Perry, Kai Zhang, Fang Tao, Kun Zhou, Deqing Hu, Yingli Han, Chongbei Zhao, Richard Alexander, Hanzhang Xu, Shiyuan Chen, Allison Peak, Kathyrn Hall, Michael Peterson, Anoja Perera, Jeffrey S. Haug, Tari Parmely, Hua Li, Bin Shen, Julia Zeitlinger, Chuan He, Linheng Li

Cell Res. 2018 Sep; 28(9): 904–917. Published online 2018 Jul 31. doi: 10.1038/s41422-018-0072-0

Correction in:: Cell Res. 2018 Oct; 28(10): 1042.

PMCID:: PMC6123498

Abstract Article PDF–3.9M

Select item 59844426.

Ythdf2-mediated m⁶A mRNA clearance modulates neural development in mice

Miaomiao Li, Xu Zhao, Wei Wang, Hailing Shi, Qingfei Pan, Zhike Lu, Sonia Peña Perez, Rajikala Suganthan, Chuan He, Magnar Bjørås, Arne Klungland

Genome Biol. 2018; 19: 69. Published online 2018 May 31. doi: 10.1186/s13059-018-1436-y

PMCID:: PMC5984442

Abstract Article PDF–2.8M

Select item 56131437.

The RNA m⁶A Reader YTHDF2 Is Essential for the Post-transcriptional Regulation of the Maternal Transcriptome and Oocyte Competence

Ivayla Ivanova, Christian Much, Monica Di Giacomo, Chiara Azzi, Marcos Morgan, Pedro N. Moreira, Jack Monahan, Claudia Carrieri, Anton J. Enright, Dónal O’Carroll

Mol Cell. 2017 Sep 21; 67(6): 1059–1067.e4. doi: 10.1016/j.molcel.2017.08.003

PMCID:: PMC5613143

Abstract Article PDF–4.1M

Select item 53398348.

YTHDF3 facilitates translation and decay of N⁶-methyladenosine-modified RNA

Hailing Shi, Xiao Wang, Zhike Lu, Boxuan S Zhao, Honghui Ma, Phillip J Hsu, Chang Liu, Chuan He

Cell Res. 2017 Mar; 27(3): 315–328. Published online 2017 Jan 20. doi: 10.1038/cr.2017.15

PMCID:: PMC5339834

Abstract Article PDF–3.0M

Select item 50073319.

YTHDF2 destabilizes m⁶A-containing RNA through direct recruitment of the CCR4–NOT deadenylase complex

Hao Du, Ya Zhao, Jinqiu He, Yao Zhang, Hairui Xi, Mofang Liu, Jinbiao Ma, Ligang Wu

Nat Commun. 2016; 7: 12626. Published online 2016 Aug 25. doi: 10.1038/ncomms12626

PMCID:: PMC5007331

Abstract Article PDF–2.7M

Select item 485124810.

Dynamic m⁶A mRNA methylation directs translational control of heat shock response

Jun Zhou, Ji Wan, Xiangwei Gao, Xingqian Zhang, Shu-Bing Qian

Nature. Author manuscript; available in PMC 2016 Apr 29.

Published in final edited form as: Nature. 2015 Oct 22; 526(7574): 591–594. Published online 2015 Oct 12. doi: 10.1038/nature15377

PMCID:: PMC4851248

Abstract Article PDF–2.3M

Select item 482569611.

N⁶-methyladenosine Modulates Messenger RNA Translation Efficiency

Xiao Wang, Boxuan Simen Zhao, Ian A. Roundtree, Zhike Lu, Dali Han, Honghui Ma, Xiaocheng Weng, Kai Chen, Hailing Shi, Chuan He

Cell. Author manuscript; available in PMC 2016 Apr 8.

Published in final edited form as: Cell. 2015 Jun 4; 161(6): 1388–1399. doi: 10.1016/j.cell.2015.05.014

PMCID:: PMC4825696

Abstract Article PDF–2.4M

Select item 459899912.

Structural Basis for the Discriminative Recognition of N⁶-Methyladenosine RNA by the Human YT521-B Homology Domain Family of Proteins

Chao Xu, Ke Liu, Hazem Ahmed, Peter Loppnau, Matthieu Schapira, Jinrong Min

J Biol Chem. 2015 Oct 9; 290(41): 24902–24913. Published online 2015 Aug 28. doi: 10.1074/jbc.M115.680389

PMCID:: PMC4598999

Abstract Article PDF–4.0M

Select item 426035113.

Structure of the YTH domain of human YTHDF2 in complex with an m⁶A mononucleotide reveals an aromatic cage for m⁶A recognition

Fudong Li, Debiao Zhao, Jihui Wu, Yunyu Shi

Cell Res. 2014 Dec; 24(12): 1490–1492. Published online 2014 Nov 21. doi: 10.1038/cr.2014.153

PMCID:: PMC4260351

Article PDF–1.3M

Select item 426035014.

Crystal structure of the YTH domain of YTHDF2 reveals mechanism for recognition of N6-methyladenosine

Tingting Zhu, Ian A Roundtree, Ping Wang, Xiao Wang, Li Wang, Chang Sun, Yuan Tian, Jie Li, Chuan He, Yanhui Xu

Cell Res. 2014 Dec; 24(12): 1493–1496. Published online 2014 Nov 21. doi: 10.1038/cr.2014.152

PMCID:: PMC4260350

Article PDF–1.1M

Select item 387771515.

m⁶A-dependent regulation of messenger RNA stability

Xiao Wang, Zhike Lu, Adrian Gomez, Gary C. Hon, Yanan Yue, Dali Han, Ye Fu, Marc Parisien, Qing Dai, Guifang Jia, Bing Ren, Tao Pan, Chuan He

Nature. Author manuscript; available in PMC 2014 Jul 2.

Published in final edited form as: Nature. 2014 Jan 2; 505(7481): 117–120. Published online 2013 Nov 27. doi: 10.1038/nature12730

PMCID:: PMC3877715

Abstract Article PDF–1.2M

Select item 317805916.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 13924117.

Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences

Mammalian Gene Collection (MGC) Program Team

Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26): 16899–16903. Published online 2002 Dec 11. doi: 10.1073/pnas.242603899

PMCID:: PMC139241

Abstract Article PDF–118K

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