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Items: 1 to 20 of 261

1.
Hypoxia‐inducible factor‐1α attenuates renal podocyte injury in male rats in a simulated high‐altitude environment by upregulating Krüppel‐like factor 4 expression
Zeng Xiaoshan, Cheng Huan, Gan Zhilin, Mo Liwen, Zeng Yan, Cheng Yue
Exp Physiol. 2024 Jul; 109(7): 1188–1198. Published online 2024 May 22. doi: 10.1113/EP091443
PMCID:
PMC11215487
AbstractArticlePDF–2.1M
2.
Aerobic exercise-induced HIF-1α upregulation in heart failure: exploring potential impacts on MCT1 and MPC1 regulation
Longfei Xu, Miaomiao Yang, Aili Wei, Zilin Wei, Yingkai Qin, Kun Wang, Bin Li, Kang Chen, Chen Liu, Chao Li, Tianhui Wang
Mol Med. 2024; 30: 83. Published online 2024 Jun 12. doi: 10.1186/s10020-024-00854-3
PMCID:
PMC11167843
AbstractArticlePDF–8.9M
3.
Lipid nephrotoxicity mediated by HIF-1α activation accelerates tubular injury in diabetic nephropathy
Zebo Hu, Qianwen Zhu, Ying Wang, Xue Deng, Hui Yang, Mingjun Zhou, Jiyuan Zhang, Hao Wang, Haosen Wang, Lin Wang, Cui Zhang, Shu Li
Ren Fail. 2024; 46(1): 2347446. Published online 2024 May 2. doi: 10.1080/0886022X.2024.2347446
PMCID:
PMC11067561
AbstractArticlePDF–9.2M
4.
Overexpression of RAD54L attenuates osteoarthritis by suppressing the HIF-1α/VEGF signaling pathway: Bioinformatics analysis and experimental validation
Zhengnan Li, Lifeng Xie, Longqiang Zou, Shiliang Xiao, Jun Tao
PLoS One. 2024; 19(4): e0298575. Published online 2024 Apr 9. doi: 10.1371/journal.pone.0298575
PMCID:
PMC11003635
AbstractArticlePDF–3.5M
5.
Mitophagy mediated by HIF-1α/FUNDC1 signaling in tubular cells protects against renal ischemia/reperfusion injury
Wenjun Zhang, Chao Guo, Yi Li, Hao Wang, Huabing Wang, Yingying Wang, Tingting Wu, Huinan Wang, Gang Cheng, Jiangwei Man, Siyu Chen, Shengjun Fu, Li Yang
Ren Fail. 2024; 46(1): 2332492. Published online 2024 Apr 7. doi: 10.1080/0886022X.2024.2332492
PMCID:
PMC11000611
AbstractArticlePDF–7.4M
6.
Adenovirus-mediated hypoxia-inducible factor 1α double-mutant promotes differentiation of bone marrow stem cells to cardiomyocytes
Yesong Wang, Chong Feng, Jiaojie Xue, Aijiao Sun, Jun Li, Juekan Wu
J Physiol Sci. 2009 Nov; 59(6): 413–420. Published online 2009 Jul 15. doi: 10.1007/s12576-009-0050-x
PMCID:
PMC10717356
AbstractArticlePDF–326K
7.
The promotion of sestrin2/AMPK signaling by HIF-1α overexpression enhances the damage caused by acute myocardial infarction
Jie Wang, Honglei Du, Qing Sun, Weiping Wan, Haifeng Zhang
BMC Cardiovasc Disord. 2023; 23: 571. Published online 2023 Nov 20. doi: 10.1186/s12872-023-03604-1
PMCID:
PMC10662688
AbstractArticlePDF–14M
8.
Panax quinquefolium L. and Salvia miltiorrhiza Bunge. Enhances Angiogenesis by Regulating the miR-155-5p/HIF-1α/VEGF Axis in Acute Myocardial Infarction
Xingxing Li, Rongpeng Liu, Wei Liu, Xin Liu, Zongjing Fan, Jie Cui, Yang Wu, Huijun Yin, Quan Lin
Drug Des Devel Ther. 2023; 17: 3249–3267. Published online 2023 Nov 7. doi: 10.2147/DDDT.S426345
PMCID:
PMC10638910
AbstractArticlePDF–12M
9.
HIF-1α活化介导的胆固醇稳态失调加速大鼠的糖尿病肾病进展
王 影, 周 明俊, 朱 倩文, 张 翠, 王 林, 李 曙, 胡 泽波
Nan Fang Yi Ke Da Xue Xue Bao. 2023 Oct 20; 43(10): 1782–1788. Chinese. doi: 10.12122/j.issn.1673-4254.2023.10.17
PMCID:
PMC10630203
AbstractArticlePDF–1.4M
10.
Autologous blood transfusion promotes autophagy and inhibits hepatocellular carcinoma progression through HIF‐1α signalling pathway
Yu Bai, Tong Liu, Ying‐Hui Cui, Zhen‐Zhou Li, Xiao‐Fang Zhou, Yong Cheng, Jin‐Huo Wang, Jian‐Rong Guo
J Cell Mol Med. 2023 May; 27(10): 1353–1361. Published online 2023 Apr 10. doi: 10.1111/jcmm.17736
PMCID:
PMC10183710
AbstractArticlePDF–2.7M
11.
Oxygen-generating microparticles downregulate HIF-1α expression, increase cardiac contractility, and mitigate ischemic injury
Kalpana Mandal, Sivakoti Sangabathuni, Reihaneh Haghniaz, Satoru Kawakita, Marvin Mecwan, Aya Nakayama, Cher Zhang, Masoud Edalati, Wei Huang, Ana Hernandez Lopez, Vadim Jucaud, Mehmet R. Dokmeci, Ali Khademhosseini
Acta Biomater. Author manuscript; available in PMC 2024 Mar 15.
Published in final edited form as: Acta Biomater. 2023 Mar 15; 159: 211–225. Published online 2023 Jan 18. doi: 10.1016/j.actbio.2023.01.030
PMCID:
PMC9992239
AbstractArticlePDF–2.1M
12.
Hypermethylation of the Bmp4 promoter dampens binding of HIF-1α and impairs its cardiac protective effects from oxidative stress in prenatally GC-exposed offspring
Ling-Tong Gao, Jian-Qiang Yuan, Zhi-Yu Zhang, Hou-Ming Zhao, Lu Gao
Cell Mol Life Sci. 2023 Mar; 80(3): 58. Published online 2023 Feb 6. doi: 10.1007/s00018-023-04703-0
PMCID:
PMC9902418
AbstractArticlePDF–8.2M
13.
HIF-1α Causes LCMT1/PP2A Deficiency and Mediates Tau Hyperphosphorylation and Cognitive Dysfunction during Chronic Hypoxia
Ling Lei, Jun Feng, Gang Wu, Zhen Wei, Jian-Zhi Wang, Bin Zhang, Rong Liu, Fei Liu, Xiaochuan Wang, Hong-Lian Li
Int J Mol Sci. 2022 Dec; 23(24): 16140. Published online 2022 Dec 17. doi: 10.3390/ijms232416140
PMCID:
PMC9783654
AbstractArticlePDF–4.3M
14.
miR-199a-5p Relieves Obstructive Sleep Apnea Syndrome-Related Hypertension by Targeting HIF-1α
Chunyan Guo, Minghui Zhang, Wei Su, Min Xu, Shumei Zhao
J Immunol Res. 2022; 2022: 7236647. Published online 2022 Jul 27. doi: 10.1155/2022/7236647
PMCID:
PMC9348946
AbstractArticlePDF–1.9M
15.
Prostaglandin E1 reduces apoptosis and improves the homing of mesenchymal stem cells in pulmonary arterial hypertension by regulating hypoxia-inducible factor 1 alpha
De-Tian Jiang, Lei Tuo, Xiao Bai, Wei-Dong Bing, Qing-Xi Qu, Xin Zhao, Guang-Min Song, Yan-Wen Bi, Wen-Yu Sun
Stem Cell Res Ther. 2022; 13: 316. Published online 2022 Jul 16. doi: 10.1186/s13287-022-03011-x
PMCID:
PMC9288720
AbstractArticlePDF–2.1M
16.
Expressions of HIF-1α and MiR-210 in aqueous humor of patients with central retinal vein occlusion combined with macular edema
Pinghui Hu, Guanghui Liu, Huaping Sun, Wei Wei
Pak J Med Sci. 2022 May-Jun; 38(5): 1327–1332. doi: 10.12669/pjms.38.5.5092
PMCID:
PMC9247752
AbstractArticlePDF–411K
17.
Hypoxia-inducible factor expression is related to apoptosis and cartilage degradation in temporomandibular joint osteoarthritis
Jun Zhang, Yu Hu, Zihan Wang, Xuelian Wu, Chun Yang, Hefeng Yang
BMC Musculoskelet Disord. 2022; 23: 583. Published online 2022 Jun 16. doi: 10.1186/s12891-022-05544-x
PMCID:
PMC9202126
AbstractArticlePDF–5.1M
18.
The protective effects of HIF-1α activation on sepsis induced intestinal mucosal barrier injury in rats model of sepsis
Xiuzhen Lei, Wenbin Teng, Ying Fan, Yeke Zhu, Liuxu Yao, Yuhong Li, Shengmei Zhu
PLoS One. 2022; 17(5): e0268445. Published online 2022 May 16. doi: 10.1371/journal.pone.0268445
PMCID:
PMC9109928
AbstractArticlePDF–1.5M
19.
LncRNA TUG1 Promotes Apoptosis, Invasion, and Angiogenesis of Retinal Endothelial Cells in Retinopathy of Prematurity via MiR-145-5p
Yuexia Wang, Yue Wang, Xue Wang, Yuan Ma, Zhaojin Li, Yu Di
Front Med (Lausanne) 2022; 9: 803214. Published online 2022 Apr 4. doi: 10.3389/fmed.2022.803214
PMCID:
PMC9014803
AbstractArticlePDF–5.0M
20.
Hypoxia-inducible factor-1alpha protects the liver against ischemia-reperfusion injury by regulating the A2B adenosine receptor
Xingjian Zhang, Peng Du, Kaifeng Luo, Yong Li, Zhongzhong Liu, Wei Wang, Cheng Zeng, Qifa Ye, Qi Xiao
Bioengineered. 2021; 12(1): 3737–3752. Published online 2021 Jul 21. doi: 10.1080/21655979.2021.1953217
PMCID:
PMC8806673
AbstractArticlePDF–2.9M

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