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Select item 104448401.

The role of TRPV2 as a regulator on the osteoclast differentiation during orthodontic tooth movement in rats

Shohei Shigemi, Tadasu Sato, Mayuri Sakamoto, Takehiro Yajima, Takahiro Honda, Hiroka Tsumaki, Toru Deguchi, Hiroyuki Ichikawa, Tomohiro Fukunaga, Itaru Mizoguchi

Sci Rep. 2023; 13: 13718. Published online 2023 Aug 22. doi: 10.1038/s41598-023-41019-2

PMCID:: PMC10444840

Abstract Article PDF–11M

Select item 97229162.

Cannabinoid non-cannabidiol site modulation of TRPV2 structure and function

Liying Zhang, Charlotte Simonsen, Lucie Zimova, Kaituo Wang, Lavanya Moparthi, Rachelle Gaudet, Maria Ekoff, Gunnar Nilsson, Ute A. Hellmich, Viktorie Vlachova, Pontus Gourdon, Peter M. Zygmunt

Nat Commun. 2022; 13: 7483. Published online 2022 Dec 5. doi: 10.1038/s41467-022-35163-y

PMCID:: PMC9722916

Abstract Article PDF–35M

Select item 96754693.

Loss of TRPV2-mediated blood flow autoregulation recapitulates diabetic retinopathy in rats

Michael O’Hare, Gema Esquiva, Mary K. McGahon, Jose Manuel Romero Hombrebueno, Josy Augustine, Paul Canning, Kevin S. Edgar, Peter Barabas, Thomas Friedel, Patrizia Cincolà, Jennifer Henry, Katie Mayne, Hannah Ferrin, Alan W. Stitt, Timothy J. Lyons, Derek P. Brazil, David J. Grieve, J. Graham McGeown, Tim M. Curtis

JCI Insight. 2022 Sep 22; 7(18): e155128. Published online 2022 Sep 22. doi: 10.1172/jci.insight.155128

PMCID:: PMC9675469

Abstract Article PDF–2.4M

Select item 92828554.

Tyrosine phosphorylation tunes chemical and thermal sensitivity of TRPV2 ion channel

Xiaoyi Mo, Peiyuan Pang, Yulin Wang, Dexiang Jiang, Mengyu Zhang, Yang Li, Peiyu Wang, Qizhi Geng, Chang Xie, Hai-Ning Du, Bo Zhong, Dongdong Li, Jing Yao

eLife. 2022; 11: e78301. Published online 2022 Jun 10. doi: 10.7554/eLife.78301

PMCID:: PMC9282855

Abstract Article PDF–7.2M

Select item 89980655.

Oxidative Stress-Induced TRPV2 Expression Increase Is Involved in Diabetic Cataracts and Apoptosis of Lens Epithelial Cells in a High-Glucose Environment

Linghui Chen, Yanzhuo Chen, Wen Ding, Tao Zhan, Jie Zhu, Lesha Zhang, Han Wang, Bing Shen, Yong Wang

Cells. 2022 Apr; 11(7): 1196. Published online 2022 Apr 2. doi: 10.3390/cells11071196

PMCID:: PMC8998065

Abstract Article PDF–4.0M

Select item 79638966.

Tetrandrine Ameliorates Myocardial Ischemia Reperfusion Injury through miR-202-5p/TRPV2

Wei Zhao, Youyang Wu, Fanhao Ye, Shiwei Huang, Hao Chen, Rui Zhou, Wenbing Jiang

Biomed Res Int. 2021; 2021: 8870674. Published online 2021 Mar 8. doi: 10.1155/2021/8870674

PMCID:: PMC7963896

Abstract Article PDF–4.5M

Select item 68874877.

The ion selectivity filter is not an activation gate in TRPV1-3 channels

Andrés Jara-Oseguera, Katherine E Huffer, Kenton J Swartz

eLife. 2019; 8: e51212. Published online 2019 Nov 14. doi: 10.7554/eLife.51212

PMCID:: PMC6887487

Abstract Article PDF–1.8M

Select item 68838318.

Oxidation of methionine residues activates the high-threshold heat-sensitive ion channel TRPV2

Tabea C. Fricke, Frank Echtermeyer, Johannes Zielke, Jeanne de la Roche, Milos R. Filipovic, Stéphane Claverol, Christine Herzog, Makoto Tominaga, Ruth A. Pumroy, Vera Y. Moiseenkova-Bell, Peter M. Zygmunt, Andreas Leffler, Mirjam J. Eberhardt

Proc Natl Acad Sci U S A. 2019 Nov 26; 116(48): 24359–24365. Published online 2019 Nov 12. doi: 10.1073/pnas.1904332116

PMCID:: PMC6883831

Abstract Article PDF–1.3M

Select item 67940889.

Molecular mechanism of TRPV2 channel modulation by cannabidiol

Ruth A Pumroy, Amrita Samanta, Yuhang Liu, Taylor ET Hughes, Siyuan Zhao, Yevgen Yudin, Tibor Rohacs, Seungil Han, Vera Y Moiseenkova-Bell

eLife. 2019; 8: e48792. Published online 2019 Sep 30. doi: 10.7554/eLife.48792

PMCID:: PMC6794088

Abstract Article PDF–3.1M

Select item 672954810.

Nociceptors Lacking TRPV1 and TRPV2 Have Normal Heat Responses

C. Jeffery Woodbury, Melissa Zwick, Shuying Wang, Jeffrey J. Lawson, Michael J. Caterina, Martin Koltzenburg, Kathryn M. Albers, H. Richard Koerber, Brian M. Davis

J Neurosci. 2004 Jul 14; 24(28): 6410–6415. doi: 10.1523/JNEUROSCI.1421-04.2004

PMCID:: PMC6729548

Abstract Article PDF–602K

Select item 663231111.

TRPV2 Enhances Axon Outgrowth through Its Activation by Membrane Stretch in Developing Sensory and Motor Neurons

Koji Shibasaki, Namie Murayama, Katsuhiko Ono, Yasuki Ishizaki, Makoto Tominaga

J Neurosci. 2010 Mar 31; 30(13): 4601–4612. doi: 10.1523/JNEUROSCI.5830-09.2010

PMCID:: PMC6632311

Abstract Article PDF–1.9M

Select item 638736212.

The Membrane Proximal Domain of TRPV1 and TRPV2 Channels Mediates Protein–Protein Interactions and Lipid Binding In Vitro

Pau Doñate-Macián, Elena Álvarez-Marimon, Francesc Sepulcre, José Luis Vázquez-Ibar, Alex Perálvarez-Marín

Int J Mol Sci. 2019 Feb; 20(3): 682. Published online 2019 Feb 5. doi: 10.3390/ijms20030682

PMCID:: PMC6387362

Abstract Article PDF–2.1M

Select item 554812013.

Structural Insight into the Assembly of TRPV Channels

Kevin W. Huynh, Matthew R. Cohen, Sudha Chakrapani, Heather A. Holdaway, Phoebe L. Stewart, Vera Y. Moiseenkova-Bell

Structure. Author manuscript; available in PMC 2017 Aug 8.

Published in final edited form as: Structure. 2014 Feb 4; 22(2): 260–268. Published online 2013 Dec 26. doi: 10.1016/j.str.2013.11.008

PMCID:: PMC5548120

Abstract Article PDF–1.3M

Select item 483383014.

Use Dependence of Heat Sensitivity of Vanilloid Receptor TRPV2

Beiying Liu, Feng Qin

Biophys J. 2016 Apr 12; 110(7): 1523–1537. Published online 2016 Apr 12. doi: 10.1016/j.bpj.2016.03.005

PMCID:: PMC4833830

Abstract Article PDF–2.4M

Select item 482061415.

Structure of the full-length TRPV2 channel by cryo-EM

Kevin W. Huynh, Matthew R. Cohen, Jiansen Jiang, Amrita Samanta, David T. Lodowski, Z. Hong Zhou, Vera Y. Moiseenkova-Bell

Nat Commun. 2016; 7: 11130. Published online 2016 Mar 29. doi: 10.1038/ncomms11130

PMCID:: PMC4820614

Abstract Article PDF–1.5M

Select item 477298716.

Lack of TRPV2 impairs thermogenesis in mouse brown adipose tissue

Wuping Sun, Kunitoshi Uchida, Yoshiro Suzuki, Yiming Zhou, Minji Kim, Yasunori Takayama, Nobuyuki Takahashi, Tsuyoshi Goto, Shigeo Wakabayashi, Teruo Kawada, Yuko Iwata, Makoto Tominaga

EMBO Rep. 2016 Mar; 17(3): 383–399. Published online 2016 Feb 11. doi: 10.15252/embr.201540819