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Select item 69973661.

A20 targets PFKL and glycolysis to inhibit the progression of hepatocellular carcinoma

Yilu Feng, Ye Zhang, Yi Cai, Ruijie Liu, Miaolong Lu, Tangzhiming Li, Ying Fu, Ming Guo, Huichao Huang, Yifu Ou, Yongheng Chen

Cell Death Dis. 2020 Feb; 11(2): 89. Published online 2020 Feb 3. doi: 10.1038/s41419-020-2278-6

PMCID:: PMC6997366

Abstract Article PDF–3.3M

Select item 67426462.

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations

Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu

Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3

PMCID:: PMC6742646

Abstract Article PDF–1.2M

Select item 62982543.

A protein-protein interaction map of the TNF-induced NF-κB signal transduction pathway

Emmy Van Quickelberghe, Delphine De Sutter, Geert van Loo, Sven Eyckerman, Kris Gevaert

Sci Data. 2018; 5: 180289. Published online 2018 Dec 18. doi: 10.1038/sdata.2018.289

PMCID:: PMC6298254

Abstract Article PDF–1.4M

Select item 56962474.

A20 enhances the radiosensitivity of hepatocellular carcinoma cells to ⁶⁰Co-γ ionizing radiation

Rui Liu, Dongli Zhao, Xiaozhi Zhang, Suxia Han, Yunyi Yang, Jinlu Ma, Du Meng

Oncotarget. 2017 Nov 3; 8(54): 93103–93116. Published online 2017 Oct 16. doi: 10.18632/oncotarget.21860

PMCID:: PMC5696247

Abstract Article PDF–5.6M

Select item 55727295.

Altered expression of Tumor Necrosis Factor Alpha -Induced Protein 3 correlates with disease severity in Ulcerative Colitis

Ishani Majumdar, Vineet Ahuja, Jaishree Paul

Sci Rep. 2017; 7: 9420. Published online 2017 Aug 25. doi: 10.1038/s41598-017-09796-9

PMCID:: PMC5572729

Abstract Article PDF–1.9M

Select item 55475186.

Association of the tandem polymorphisms (rs148314165, rs200820567) in TNFAIP3 with chronic hepatitis B virus infection in Chinese Han population

Na Li, Ying Shi, Pingping Zhang, Jiao Sang, Fang Li, Huan Deng, Yi Lv, Qunying Han, Zhengwen Liu

Virol J. 2017; 14: 148. Published online 2017 Aug 7. doi: 10.1186/s12985-017-0814-5

PMCID:: PMC5547518

Abstract Article PDF–393K

Select item 53245537.

The deubiquitinating enzyme, ubiquitin‐specific peptidase 50, regulates inflammasome activation by targeting the ASC adaptor protein

Jae Young Lee, Dongyeob Seo, Jiyeon You, Sehee Chung, Jin Seok Park, Ji‐Hyung Lee, Su Myung Jung, Youn Sook Lee, Seok Hee Park

FEBS Lett. 2017 Feb; 591(3): 479–490. Published online 2017 Jan 29. doi: 10.1002/1873-3468.12558

PMCID:: PMC5324553

Abstract Article PDF–638K

Select item 51433848.

A20 prevents chronic liver inflammation and cancer by protecting hepatocytes from death

L Catrysse, M Farhang Ghahremani, L Vereecke, S A Youssef, C Mc Guire, M Sze, A Weber, M Heikenwalder, A de Bruin, R Beyaert, G van Loo

Cell Death Dis. 2016 Jun; 7(6): e2250. Published online 2016 Jun 2. doi: 10.1038/cddis.2016.154

PMCID:: PMC5143384

Abstract Article PDF–2.5M

Select item 49293009.

A20 deficiency leads to angiogenesis of pulmonary artery endothelial cells through stronger NF‐κB activation under hypoxia

Jing Li, Linlin Zhang, Yueming Zhang, Ying Liu, Hongyue Zhang, Liuping Wei, Tingting Shen, Chun Jiang, Daling Zhu

J Cell Mol Med. 2016 Jul; 20(7): 1319–1328. Published online 2016 Mar 17. doi: 10.1111/jcmm.12816

PMCID:: PMC4929300

Abstract Article PDF–1.0M

Select item 463419110.

A20 suppresses hepatocellular carcinoma proliferation and metastasis through inhibition of Twist1 expression

Haiyang Chen, Liang Hu, Zaili Luo, Jian Zhang, Cunzhen Zhang, Bijun Qiu, Liwei Dong, Yexiong Tan, Jin Ding, Shanhua Tang, Feng Shen, Zhong Li, Hongyang Wang

Mol Cancer. 2015; 14: 186. Published online 2015 Nov 4. doi: 10.1186/s12943-015-0454-6

PMCID:: PMC4634191

Abstract Article PDF–3.6M

Select item 461277911.

The Prognostic Role of SOCS3 and A20 in Human Cholangiocarcinoma

Yimin Wang, Ming Wan, Qingxin Zhou, Hao Wang, Zhidong Wang, Xiangyu Zhong, Lei Zhang, Sheng Tai, Yunfu Cui

PLoS One. 2015; 10(10): e0141165. Published online 2015 Oct 20. doi: 10.1371/journal.pone.0141165

PMCID:: PMC4612779

Abstract Article PDF–2.8M

Select item 426658812.

A proteome-scale map of the human interactome network

Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal

Cell. Author manuscript; available in PMC 2015 Nov 20.

Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050

PMCID:: PMC4266588

Abstract Article PDF–3.1M

Select item 426337113.

A Massively Parallel Pipeline to Clone DNA Variants and Examine Molecular Phenotypes of Human Disease Mutations

Xiaomu Wei, Jishnu Das, Robert Fragoza, Jin Liang, Francisco M. Bastos de Oliveira, Hao Ran Lee, Xiujuan Wang, Matthew Mort, Peter D. Stenson, David N. Cooper, Steven M. Lipkin, Marcus B. Smolka, Haiyuan Yu

PLoS Genet. 2014 Dec; 10(12): e1004819. Published online 2014 Dec 11. doi: 10.1371/journal.pgen.1004819

PMCID:: PMC4263371

Abstract Article PDF–7.6M

Select item 402118214.

Ubiquitin ligase A20 regulates p53 protein in human colon epithelial cells

Jing Liu, Shaobo Yang, Zhiqiang Wang, Xiao Chen, Ziqi Zhang

J Biomed Sci. 2013; 20(1): 74. Published online 2013 Oct 7. doi: 10.1186/1423-0127-20-74

PMCID:: PMC4021182

Abstract Article PDF–830K

Select item 370520815.

OTU Deubiquitinases Reveal Mechanisms of Linkage Specificity and Enable Ubiquitin Chain Restriction Analysis

Tycho E.T. Mevissen, Manuela K. Hospenthal, Paul P. Geurink, Paul R. Elliott, Masato Akutsu, Nadia Arnaudo, Reggy Ekkebus, Yogesh Kulathu, Tobias Wauer, Farid El Oualid, Stefan M.V. Freund, Huib Ovaa, David Komander

Cell. 2013 Jul 3; 154(1): 169–184. doi: 10.1016/j.cell.2013.05.046

PMCID:: PMC3705208

Abstract Article

Select item 367556216.

Immune Responsive Gene 1 (IRG1) Promotes Endotoxin Tolerance by Increasing A20 Expression in Macrophages through Reactive Oxygen Species

Yingke Li, Peng Zhang, Chengcai Wang, Chaofeng Han, Jun Meng, Xingguang Liu, Sheng Xu, Nan Li, Qingqing Wang, Xueyin Shi, Xuetao Cao

J Biol Chem. 2013 Jun 7; 288(23): 16225–16234. Published online 2013 Apr 22. doi: 10.1074/jbc.M113.454538

PMCID:: PMC3675562

Abstract Article PDF–1.5M

Select item 360637317.

The Ubiquitin-Editing Enzyme A20 Restricts Nucleotide-Binding Oligomerization Domain Containing 2-Triggered Signals

Osamu Hitotsumatsu, Regina-Celeste Ahmad, Rita Tavares, Min Wang, Dana Philpott, Emre E. Turer, Bettina L. Lee, Nataliya Shiffin, Rommel Advincula, Barbara A. Malynn, Catherine Werts, Averil Ma

Immunity. Author manuscript; available in PMC 2013 Mar 22.

Published in final edited form as: Immunity. 2008 Mar; 28(3): 381–390. doi: 10.1016/j.immuni.2008.02.002

PMCID:: PMC3606373

Abstract Article PDF–2.1M

Select item 359454518.

Regulation of NF-κB by Ubiquitination

Jueqi Chen, Zhijian J. Chen

Curr Opin Immunol. Author manuscript; available in PMC 2014 Feb 1.

Published in final edited form as: Curr Opin Immunol. 2013 Feb; 25(1): 4–12. Published online 2013 Jan 8. doi: 10.1016/j.coi.2012.12.005

PMCID:: PMC3594545

Abstract Article PDF–1.3M

Select item 358239919.

Failure to Regulate TNF-Induced NF-κB and Cell Death Responses in A20-Deficient Mice

Eric G. Lee, David L. Boone, Sophia Chai, Shon L. Libby, Marcia Chien, James P. Lodolce, Averil Ma

Science. Author manuscript; available in PMC 2013 Feb 26.

Published in final edited form as: Science. 2000 Sep 29; 289(5488): 2350–2354. doi: 10.1126/science.289.5488.2350

PMCID:: PMC3582399

Abstract Article PDF–3.3M

Select item 317805920.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

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