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Select item 108304321.

Intermittent short-duration reoxygenation relieves high-altitude pulmonary hypertension via NOX4/H₂O₂/PPAR-γ axis

Shaohua Li, Qiang Lyu, Qixin Shi, Yungang Bai, Xinling Ren, Jin Ma

Clin Sci (Lond) 2024 Feb; 138(3): 103–115. Published online 2024 Jan 30. doi: 10.1042/CS20231508

PMCID:: PMC10830432

Abstract Article PDF–6.2M

Select item 103689472.

Maternal exercise represses Nox4 via SIRT1 to prevent vascular oxidative stress and endothelial dysfunction in SHR offspring

Yanyan Zhang, Meiling Shan, Xiaozhen Ding, Hualing Sun, Fang Qiu, Lijun Shi

Front Endocrinol (Lausanne) 2023; 14: 1219194. Published online 2023 Jul 12. doi: 10.3389/fendo.2023.1219194

PMCID:: PMC10368947

Abstract Article PDF–25M

Select item 98124193.

Functional Significance of Angiotensin Receptor Type 2 in the Neuroplasticity of Autonomic Ganglia in (mRen2)27 Transgenic Hypertensive Rats

Berwin Singh Swami Vetha, Rachel Byrum, Kaisi Peele, Debra Diz, Azeez Aileru

J Cardiovasc Pharmacol. 2023 Jan; 81(1): 76–84. Published online 2022 Sep 16. doi: 10.1097/FJC.0000000000001368

PMCID:: PMC9812419

Abstract Article PDF–864K

Select item 97862654.

MicroRNA‐454 modulates the oxidative stress and neuronal apoptosis after cerebral ischemia/reperfusion injury via targeting NADPH oxidase 4 (NOX4)

Tao Zhang, Haiping Han, Yan Zhou, Zhimei Liu, Tingjie Ma, Xuqing Cao

J Biochem Mol Toxicol. 2022 Oct; 36(10): e23153. Published online 2022 Aug 31. doi: 10.1002/jbt.23153

PMCID:: PMC9786265

Abstract Article PDF–5.0M

Select item 93547965.

Advanced oxidation protein products induce annulus fibrosus cell senescence through a NOX4-dependent, MAPK-mediated pathway and accelerate intervertebral disc degeneration

Xiangheng Dai, Yu Chen, Zihan Yu, Congrui Liao, Zhongyuan Liu, Jianting Chen, Qian Wu

PeerJ. 2022; 10: e13826. Published online 2022 Aug 2. doi: 10.7717/peerj.13826

PMCID:: PMC9354796

Abstract Article PDF–36M

Select item 88091186.

NOX4 stimulates ANF secretion via activation of the Sirt1/Nrf2/ATF3/4 axis in hypoxic beating rat atria

Zhi-Yu Li, Ying Liu, Yue-Ying Wang, Xiang Li, Zhuo-Na Han, Lan Hong, Ying-Shun Li, Xun Cui

Mol Med Rep. 2022 Mar; 25(3): 84. Published online 2022 Jan 13. doi: 10.3892/mmr.2022.12600

PMCID:: PMC8809118

Abstract Article PDF–4.8M

Select item 86184897.

In Vivo Investigation of the Ameliorating Effect of Tempol against MIA-Induced Knee Osteoarthritis in Rats: Involvement of TGF-β1/SMAD3/NOX4 Cue

Hagar B. Abo-zalam, Rania M. Abdelsalam, Rehab F. Abdel-Rahman, Mohamed F. Abd-Ellah, Mahmoud M. Khattab

Molecules. 2021 Nov; 26(22): 6993. Published online 2021 Nov 19. doi: 10.3390/molecules26226993

PMCID:: PMC8618489

Abstract Article PDF–6.4M

Select item 83830398.

Protective effects of metformin against myocardial ischemia-reperfusion injury via AMPK-dependent suppression of NOX4

Yan Shi, Shu-Ai Hou

Mol Med Rep. 2021 Oct; 24(4): 712. Published online 2021 Aug 10. doi: 10.3892/mmr.2021.12351

PMCID:: PMC8383039

Abstract Article PDF–953K

Select item 78759219.

Neuregulin‐1 alleviate oxidative stress and mitigate inflammation by suppressing NOX4 and NLRP3/caspase‐1 in myocardial ischaemia‐reperfusion injury

Fuhua Wang, Huan Wang, Xuejing Liu, Haiyi Yu, Xiaomin Huang, Wei Huang, Guisong Wang

J Cell Mol Med. 2021 Feb; 25(3): 1783–1795. Published online 2021 Jan 20. doi: 10.1111/jcmm.16287

PMCID:: PMC7875921

Abstract Article PDF–2.1M

Select item 772204210.

NOX4-dependent regulation of ENaC in hypertension and diabetic kidney disease

Tengis S. Pavlov, Oleg Palygin, Elena Isaeva, Vladislav Levchenko, Sherif Khedr, Gregory Blass, Daria V. Ilatovskaya, Allen W. Cowley, Jr., Alexander Staruschenko

FASEB J. Author manuscript; available in PMC 2021 Oct 1.

Published in final edited form as: FASEB J. 2020 Oct; 34(10): 13396–13408. Published online 2020 Aug 16. doi: 10.1096/fj.202000966RR

PMCID:: PMC7722042

Abstract Article PDF–1.1M

Select item 768315611.

Oxymatrine Ameliorates Memory Impairment in Diabetic Rats by Regulating Oxidative Stress and Apoptosis: Involvement of NOX2/NOX4

Yongpan Huang, Xinliang Li, Xi Zhang, Jiayu Tang

Oxid Med Cell Longev. 2020; 2020: 3912173. Published online 2020 Nov 16. doi: 10.1155/2020/3912173

PMCID:: PMC7683156

Abstract Article PDF–2.7M

Select item 752794712.

Nox4 regulates InsP₃ receptor‐dependent Ca²⁺ release into mitochondria to promote cell survival

Matteo Beretta, Celio XC Santos, Chris Molenaar, Anne D Hafstad, Chris CJ Miller, Aram Revazian, Kai Betteridge, Katrin Schröder, Katrin Streckfuß‐Bömeke, James H Doroshow, Roland A Fleck, Tsung‐Ping Su, Vsevolod V Belousov, Maddy Parsons, Ajay M Shah

EMBO J. 2020 Oct 1; 39(19): e103530. Published online 2020 Aug 10. doi: 10.15252/embj.2019103530

PMCID:: PMC7527947

Abstract Article PDF–3.6M

Select item 727273313.

NADPH oxidase-mediated endothelial injury in HIV- and opioid-induced pulmonary arterial hypertension

Stuti Agarwal, Himanshu Sharma, Ling Chen, Navneet K. Dhillon

Am J Physiol Lung Cell Mol Physiol. 2020 May 1; 318(5): L1097–L1108. Published online 2020 Apr 1. doi: 10.1152/ajplung.00480.2019

PMCID:: PMC7272733

Abstract Article

Select item 723212814.

Overexpression of mechanical sensitive miR-337-3p alleviates ectopic ossification in rat tendinopathy model via targeting IRS1 and Nox4 of tendon-derived stem cells

Yiyun Geng, Xiaoying Zhao, Jiajia Xu, Xudong Zhang, Guoli Hu, Sai-Chuen Fu, Kerong Dai, Xiaodong Chen, Yung shu-huang Patrick, Xiaoling Zhang

J Mol Cell Biol. 2020 Apr; 12(4): 305–317. Published online 2019 May 8. doi: 10.1093/jmcb/mjz030

PMCID:: PMC7232128

Abstract Article PDF–2.2M

Select item 717531615.

Chronic Exposure to Fluoride Affects GSH Level and NOX4 Expression in Rat Model of This Element of Neurotoxicity

Karolina Dec, Agnieszka Łukomska, Karolina Skonieczna-Żydecka, Karolina Jakubczyk, Maciej Tarnowski, Anna Lubkowska, Irena Baranowska-Bosiacka, Daniel Styburski, Marta Skórka-Majewicz, Dominika Maciejewska, Izabela Gutowska

Biomolecules. 2020 Mar; 10(3): 422. Published online 2020 Mar 9. doi: 10.3390/biom10030422

PMCID:: PMC7175316

Abstract Article PDF–1.4M

Select item 713931616.

Oxidative Stress and Mitochondrial Abnormalities Contribute to Decreased Endothelial Nitric Oxide Synthase Expression and Renal Disease Progression in Early Experimental Polycystic Kidney Disease

Alp S. Kahveci, Tania T. Barnatan, Ali Kahveci, Alexis E. Adrian, Jennifer Arroyo, Alfonso Eirin, Peter C. Harris, Amir Lerman, Lilach O. Lerman, Vicente E. Torres, Maria V. Irazabal

Int J Mol Sci. 2020 Mar; 21(6): 1994. Published online 2020 Mar 14. doi: 10.3390/ijms21061994