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Select item 111151111.

Amyloid β-induced FOXRED2 mediates neuronal cell death via inhibition of proteasome activity

SangMi Shim, WonJae Lee, HaeWon Chung, Yong-Keun Jung

Cell Mol Life Sci. 2011 Jun; 68(12): 2115–2127. Published online 2010 Oct 23. doi: 10.1007/s00018-010-0561-x

PMCID:: PMC11115111

Abstract Article PDF–752K

Select item 102514912.

Sex-specific effects of ethanol consumption in older Fischer 344 rats on microglial dynamics and Aβ_(1–42) accumulation

Paige Marsland, Andrew S. Vore, Evan DaPrano, Joanna M. Paluch, Ashley A. Blackwell, Elena I. Varlinskaya, Terrence Deak

Alcohol. Author manuscript; available in PMC 2023 Jun 9.

Published in final edited form as: Alcohol. 2023 Mar; 107: 108–118. Published online 2022 Sep 22. doi: 10.1016/j.alcohol.2022.08.013

PMCID:: PMC10251491

Abstract Article PDF–2.1M

Select item 101830393.

Pathological convergence of APP and SNCA deficiency in hippocampal degeneration of young rats

Yajie Wang, Zhikang Miao, Chang Xu, Ying Cai, Yuting Yang, Yue Hu, Mengna Zhao, Yue Shao, Zhiqiang Li, Jincao Chen, Shi Chen, Lianrong Wang

Cell Death Dis. 2023 May; 14(5): 325. Published online 2023 May 13. doi: 10.1038/s41419-023-05846-5

PMCID:: PMC10183039

Abstract Article PDF–3.8M

Select item 88076124.

An App knock-in rat model for Alzheimer’s disease exhibiting Aβ and tau pathologies, neuronal death and cognitive impairments

Keliang Pang, Richeng Jiang, Wei Zhang, Zhengyi Yang, Lin-Lin Li, Makoto Shimozawa, Simone Tambaro, Johanna Mayer, Baogui Zhang, Man Li, Jiesi Wang, Hang Liu, Ailing Yang, Xi Chen, Jiazheng Liu, Bengt Winblad, Hua Han, Tianzi Jiang, Weiwen Wang, Per Nilsson, Wei Guo, Bai Lu

Cell Res. 2022 Feb; 32(2): 157–175. Published online 2021 Nov 17. doi: 10.1038/s41422-021-00582-x

PMCID:: PMC8807612

Abstract Article PDF–9.4M

Select item 87824175.

A PDK-1 allosteric agonist neutralizes insulin signaling derangements and beta-amyloid toxicity in neuronal cells and in vitro

Henry Querfurth, John Marshall, Keykavous Parang, Mengia S. Rioult-Pedotti, Rakesh Tiwari, Bumsup Kwon, Steve Reisinger, Han-Kyu Lee

PLoS One. 2022; 17(1): e0261696. Published online 2022 Jan 21. doi: 10.1371/journal.pone.0261696

Correction in:: PLoS One. 2024; 19(5): e0304731.

PMCID:: PMC8782417

Abstract Article PDF–2.0M

Select item 87006056.

Ellagic Acid Modulates the Amyloid Precursor Protein Gene via Superoxide Dismutase Regulation in the Entorhinal Cortex in an Experimental Alzheimer’s Model

Wafaa S. Ramadan, Saleh Alkarim

Cells. 2021 Dec; 10(12): 3511. Published online 2021 Dec 13. doi: 10.3390/cells10123511

PMCID:: PMC8700605

Abstract Article PDF–6.6M

Select item 85220967.

Characterization of an APP/tau rat model of Alzheimer’s disease by positron emission tomography and immunofluorescent labeling

Thomas Filip, Severin Mairinger, Joerg Neddens, Michael Sauberer, Stefanie Flunkert, Johann Stanek, Thomas Wanek, Nobuyuki Okamura, Oliver Langer, Birgit Hutter-Paier, Claudia Kuntner

Alzheimers Res Ther. 2021; 13: 175. Published online 2021 Oct 16. doi: 10.1186/s13195-021-00916-2

PMCID:: PMC8522096

Abstract Article PDF–1.6M

Select item 75154808.

Electroacupuncture at GV24 and bilateral GB13 improves cognitive ability via influences the levels of Aβ, p-tau (s396) and p-tau (s404) in the hippocampus of Alzheimer’s disease model rats

Yang Yang, Shaowen Hu, Haibo Lin, Jiang He, Chunzhi Tang

Neuroreport. 2020 Oct 14; 31(15): 1072–1083. Published online 2020 Aug 31. doi: 10.1097/WNR.0000000000001518

PMCID:: PMC7515480

Abstract Article PDF–2.2M

Select item 73833689.

Intramitochondrial proteostasis is directly coupled to α-synuclein and amyloid β1-42 pathologies

Janin Lautenschläger, Sara Wagner-Valladolid, Amberley D. Stephens, Ana Fernández-Villegas, Colin Hockings, Ajay Mishra, James D. Manton, Marcus J. Fantham, Meng Lu, Eric J. Rees, Clemens F. Kaminski, Gabriele S. Kaminski Schierle

J Biol Chem. 2020 Jul 24; 295(30): 10138–10152. Published online 2020 May 8. doi: 10.1074/jbc.RA119.011650

PMCID:: PMC7383368

Abstract Article PDF–3.0M

Select item 724731810.

Knock-in rats with homozygous PSEN1^L435F Alzheimer mutation are viable and show selective γ-secretase activity loss causing low Aβ40/42 and high Aβ43

Marc D. Tambini, Luciano D'Adamio

J Biol Chem. 2020 May 22; 295(21): 7442–7451. Published online 2020 Apr 7. doi: 10.1074/jbc.RA120.012542

PMCID:: PMC7247318

Abstract Article PDF–2.7M

Select item 720167511.

Effect of Quercetin on PC12 Alzheimer's Disease Cell Model Induced by Aβ_25-35 and Its Mechanism Based on Sirtuin1/Nrf2/HO-1 Pathway

Xinjun Yu, Yicai Li, Xiaohua Mu

Biomed Res Int. 2020; 2020: 8210578. Published online 2020 Apr 27. doi: 10.1155/2020/8210578

PMCID:: PMC7201675

Abstract Article PDF–926K

Select item 719614012.

(-)-cis-Carveol, a Natural Compound, Improves β-Amyloid-Peptide 1-42-Induced Memory Impairment and Oxidative Stress in the Rat Hippocampus

Lucian Hritcu, Razvan Stefan Boiangiu, Mayara Castro de Morais, Damião Pergentino de Sousa

Biomed Res Int. 2020; 2020: 8082560. Published online 2020 Apr 22. doi: 10.1155/2020/8082560

PMCID:: PMC7196140

Abstract Article PDF–884K

Select item 679369313.

Trafficking of Cell-Surface β-Amyloid Precursor Protein: Evidence that a Sorting Intermediate Participates in Synaptic Vesicle Recycling

Numa R. Marquez-Sterling, Amy C. Y. Lo, Sangram S. Sisodia, Edward H. Koo

J Neurosci. 1997 Jan 1; 17(1): 140–151. doi: 10.1523/JNEUROSCI.17-01-00140.1997

PMCID:: PMC6793693

Abstract Article PDF–930K

Select item 678259814.

Role of Phosphorylation of Alzheimer’s Amyloid Precursor Protein during Neuronal Differentiation

Kanae Ando, Masaki Oishi, Shizu Takeda, Ko-ichi Iijima, Toshio Isohara, Angus C. Nairn, Yutaka Kirino, Paul Greengard, Toshiharu Suzuki

J Neurosci. 1999 Jun 1; 19(11): 4421–4427. doi: 10.1523/JNEUROSCI.19-11-04421.1999

PMCID:: PMC6782598

Abstract Article PDF–1.3M

Select item 678215615.

The Amyloid Precursor Protein Interacts with G_o Heterotrimeric Protein within a Cell Compartment Specialized in Signal Transduction

Emmanuel Brouillet, Alain Trembleau, Damien Galanaud, Michel Volovitch, Colette Bouillot, Cécile Valenza, Alain Prochiantz, Bernadette Allinquant

J Neurosci. 1999 Mar 1; 19(5): 1717–1727. doi: 10.1523/JNEUROSCI.19-05-01717.1999

PMCID:: PMC6782156

Abstract Article PDF–830K

Select item 676382516.

Amyloid β₄₂ Activates a G-Protein-Coupled Chemoattractant Receptor, FPR-Like-1

Yingying Le, Wanghua Gong, H. Lee Tiffany, Alexei Tumanov, Sergei Nedospasov, Weiping Shen, Nancy M. Dunlop, Ji-Liang Gao, Philip M. Murphy, Joost J. Oppenheim, Ji Ming Wang

J Neurosci. 2001 Jan 15; 21(2): RC123. doi: 10.1523/JNEUROSCI.21-02-j0003.2001

PMCID:: PMC6763825

Abstract PDF–273K

Select item 676276417.

β-Amyloid Activates the Mitogen-Activated Protein Kinase Cascade via Hippocampal α7 Nicotinic Acetylcholine Receptors:In Vitro and In Vivo Mechanisms Related to Alzheimer's Disease

Kelly T. Dineley, Marcus Westerman, Duy Bui, Karen Bell, Karen Hsiao Ashe, J. David Sweatt

J Neurosci. 2001 Jun 15; 21(12): 4125–4133. doi: 10.1523/JNEUROSCI.21-12-04125.2001

PMCID:: PMC6762764

Abstract Article PDF–351K

Select item 675886218.

The Relationship between Aβ and Memory in the Tg2576 Mouse Model of Alzheimer's Disease

Marcus A. Westerman, Deirdre Cooper-Blacketer, Ami Mariash, Linda Kotilinek, Takeshi Kawarabayashi, Linda H. Younkin, George A. Carlson, Steven G. Younkin, Karen H. Ashe

J Neurosci. 2002 Mar 1; 22(5): 1858–1867. doi: 10.1523/JNEUROSCI.22-05-01858.2002