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Select item 74907181.

Chromatin accessibility mapping of the striatum identifies tyrosine kinase FYN as a therapeutic target for heroin use disorder

Gabor Egervari, Diana Akpoyibo, Tanni Rahman, John F. Fullard, James E. Callens, Joseph A. Landry, Annie Ly, Xianxiao Zhou, Noël Warren, Mads E. Hauberg, Gabriel Hoffman, Randy Ellis, Jacqueline-Marie N. Ferland, Michael L. Miller, Eva Keller, Bin Zhang, Panos Roussos, Yasmin L. Hurd

Nat Commun. 2020; 11: 4634. Published online 2020 Sep 14. doi: 10.1038/s41467-020-18114-3

PMCID:: PMC7490718

Abstract Article PDF–1.8M

Select item 71832102.

Linkage of non-receptor tyrosine kinase Fyn to mGlu5 receptors in striatal neurons in a depression model

Li-Min Mao, John Q. Wang

Neuroscience. Author manuscript; available in PMC 2021 May 1.

Published in final edited form as: Neuroscience. 2020 May 1; 433: 11–20. Published online 2020 Mar 5. doi: 10.1016/j.neuroscience.2020.02.048

PMCID:: PMC7183210

Abstract Article PDF–956K

Select item 70155803.

Leptin Controls Glutamatergic Synaptogenesis and NMDA-Receptor Trafficking via Fyn Kinase Regulation of NR2B

Tyler Bland, Mingyan Zhu, Crystal Dillon, Gulcan Semra Sahin, Jose Luis Rodriguez-Llamas, Suzanne M Appleyard, Gary A Wayman

Endocrinology. 2020 Feb; 161(2): bqz030. Published online 2019 Dec 16. doi: 10.1210/endocr/bqz030

PMCID:: PMC7015580

Abstract Article

Select item 67626134.

A Unique Role for Fyn in CNS Myelination

Brian R. Sperber, Éilis A. Boyle-Walsh, Mark J. Engleka, Paul Gadue, Alan C. Peterson, Paul L. Stein, Steven S. Scherer, F. Arthur McMorris

J Neurosci. 2001 Mar 15; 21(6): 2039–2047. doi: 10.1523/JNEUROSCI.21-06-02039.2001

PMCID:: PMC6762613

Abstract Article PDF–732K

Select item 67584985.

Process Outgrowth of Oligodendrocytes Is Promoted by Interaction of Fyn Kinase with the Cytoskeletal Protein Tau

Corinna Klein, Eva-Maria Krämer, Anne-Marie Cardine, Burkhardt Schraven, Roland Brandt, Jacqueline Trotter

J Neurosci. 2002 Feb 1; 22(3): 698–707. doi: 10.1523/JNEUROSCI.22-03-00698.2002

PMCID:: PMC6758498

Abstract Article PDF–584K

Select item 67304426.

Phosphorylation of Tau by Fyn: Implications for Alzheimer's Disease

Gloria Lee, Ramasamy Thangavel, Vandana M. Sharma, Joel M. Litersky, Kiran Bhaskar, Sandy M. Fang, Lana H. Do, Athena Andreadis, Gary Van Hoesen, Hanna Ksiezak-Reding

J Neurosci. 2004 Mar 3; 24(9): 2304–2312. doi: 10.1523/JNEUROSCI.4162-03.2004

PMCID:: PMC6730442

Abstract Article PDF–533K

Select item 67256707.

Absence of Fyn and Src Causes a Reeler-Like Phenotype

Gloria Kuo, Lionel Arnaud, Priscilla Kronstad-O'Brien, Jonathan A. Cooper

J Neurosci. 2005 Sep 14; 25(37): 8578–8586. doi: 10.1523/JNEUROSCI.1656-05.2005

PMCID:: PMC6725670

Abstract Article PDF–1.7M

Select item 66706978.

Voltage-Gated Na⁺ Channel β1 Subunit-Mediated Neurite Outgrowth Requires Fyn Kinase and Contributes to Postnatal CNS Development In Vivo

William J. Brackenbury, Tigwa H. Davis, Chunling Chen, Emily A. Slat, Matthew J. Detrow, Travis L. Dickendesher, Barbara Ranscht, Lori L. Isom

J Neurosci. 2008 Mar 19; 28(12): 3246–3256. doi: 10.1523/JNEUROSCI.5446-07.2008

PMCID:: PMC6670697

Abstract Article PDF–477K

Select item 66705789.

Cdk5 Phosphorylation of WAVE2 Regulates Oligodendrocyte Precursor Cell Migration through Nonreceptor Tyrosine Kinase Fyn

Yuki Miyamoto, Junji Yamauchi, Akito Tanoue

J Neurosci. 2008 Aug 13; 28(33): 8326–8337. doi: 10.1523/JNEUROSCI.1482-08.2008

PMCID:: PMC6670578

Abstract Article PDF–706K

Select item 560883410.

An Essential Role of Fyn in the Modulation of Metabotropic Glutamate Receptor 1 in Neurons

Dao-Zhong Jin, Li-Min Mao, John Q. Wang

eNeuro. 2017 Jul-Aug; 4(4): ENEURO.0096-17.2017. Prepublished online 2017 Aug 24. Published online 2017 May 30. doi: 10.1523/ENEURO.0096-17.2017

PMCID:: PMC5608834

Abstract Article PDF–2.0M

Select item 509303211.

Dynamically coupled residues within the SH2 domain of FYN are key to unlocking its activity

Radu Huculeci, Elisa Cilia, Agatha Lyczek, Lieven Buts, Klaartje Houben, Markus A. Seeliger, Nico van Nuland, Tom Lenaerts

Structure. Author manuscript; available in PMC 2017 Nov 1.

Published in final edited form as: Structure. 2016 Nov 1; 24(11): 1947–1959. Published online 2016 Sep 29. doi: 10.1016/j.str.2016.08.016

PMCID:: PMC5093032

Abstract Article PDF–2.8M

Select item 500496112.

Tyrosine kinase FYN negatively regulates NOX4 in cardiac remodeling

Shouji Matsushima, Junya Kuroda, Peiyong Zhai, Tong Liu, Shohei Ikeda, Narayani Nagarajan, Shin-ichi Oka, Takashi Yokota, Shintaro Kinugawa, Chiao-Po Hsu, Hong Li, Hiroyuki Tsutsui, Junichi Sadoshima

J Clin Invest. 2016 Sep 1; 126(9): 3403–3416. Published online 2016 Aug 15. doi: 10.1172/JCI85624

PMCID:: PMC5004961

Abstract Article PDF–2.4M

Select item 498779213.

PSD-95 stabilizes NMDA receptors by inducing the degradation of STEP₆₁

Sehoon Won, Salvatore Incontro, Roger A. Nicoll, Katherine W. Roche

Proc Natl Acad Sci U S A. 2016 Aug 9; 113(32): E4736–E4744. Published online 2016 Jul 25. doi: 10.1073/pnas.1609702113

PMCID:: PMC4987792

Abstract Article PDF–1.5M

Select item 484477314.

Novel Autophosphorylation Sites of Src Family Kinases Regulate Kinase Activity and SH2 Domain Binding Capacity

Marion E. Weir, Jacqueline E. Mann, Thomas Corwin, Zachary W. Fulton, Jennifer M. Hao, Jeanine F. Maniscalco, Marie C. Kenney, Kristal M. Roman Roque, Elizabeth F. Chapdelaine, Ulrich Stelzl, Paula B. Deming, Bryan A. Ballif, Karen L. Hinkle

FEBS Lett. Author manuscript; available in PMC 2017 Apr 13.

Published in final edited form as: FEBS Lett. 2016 Apr; 590(8): 1042–1052. Published online 2016 Apr 13. doi: 10.1002/1873-3468.12144

PMCID:: PMC4844773

Abstract Article PDF–1.1M

Select item 476277815.

A Central Nervous System-Dependent Intron-Embedded Gene Encodes a Novel Murine Fyn Binding Protein

Noureddine Ben Khalaf, Safa Taha, Moiz Bakhiet, M. Dahmani Fathallah

PLoS One. 2016; 11(2): e0149612. Published online 2016 Feb 22. doi: 10.1371/journal.pone.0149612

PMCID:: PMC4762778

Abstract Article PDF–2.9M

Select item 474455116.

Dopamine D2 receptors are involved in the regulation of Fyn and mGluR5 phosphorylation in the rat striatum in vivo

Li-Min Mao, John Q. Wang

J Neurosci Res. Author manuscript; available in PMC 2016 Oct 1.

Published in final edited form as: J Neurosci Res. 2016 Apr; 94(4): 329–338. Published online 2016 Jan 17. doi: 10.1002/jnr.23713

PMCID:: PMC4744551

Abstract Article PDF–704K

Select item 465516417.

Dopaminergic and cholinergic regulation of Fyn tyrosine kinase phosphorylation in the rat striatum in vivo

Li-Min Mao, John Q. Wang

Neuropharmacology. Author manuscript; available in PMC 2016 Dec 1.

Published in final edited form as: Neuropharmacology. 2015 Dec; 99: 491–499. Published online 2015 Aug 13. doi: 10.1016/j.neuropharm.2015.08.017

PMCID:: PMC4655164

Abstract Article PDF–1.4M

Select item 451662818.

STriatal-Enriched protein tyrosine Phosphatase (STEP) Regulates the PTPα/Fyn Signaling Pathway

Jian Xu, Pradeep Kurup, Ethan Foscue, Paul J. Lombroso

J Neurochem. Author manuscript; available in PMC 2016 Aug 1.

Published in final edited form as: J Neurochem. 2015 Aug; 134(4): 629–641. Published online 2015 May 25. doi: 10.1111/jnc.13160

PMCID:: PMC4516628

Abstract Article PDF–1.2M

Select item 431857219.

AlphaScreen HTS and Live Cell Bioluminescence Resonance Energy Transfer (BRET) Assays for Identification of Tau–Fyn SH3 Interaction Inhibitors for Alzheimer’s Disease

J. Nicholas Cochran, Pauleatha V. Diggs, N. Miranda Nebane, Lynn Rasmussen, E. Lucile White, Robert Bostwick, Joseph A. Maddry, Mark J. Suto, Erik D. Roberson

J Biomol Screen. Author manuscript; available in PMC 2015 Dec 1.

Published in final edited form as: J Biomol Screen. 2014 Dec; 19(10): 1338–1349. Published online 2014 Aug 25. doi: 10.1177/1087057114547232