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Select item 73498301.

Maternal Tryptophan Supplementation Protects Adult Rat Offspring against Hypertension Programmed by Maternal Chronic Kidney Disease: Implication of Tryptophan-Metabolizing Microbiome and Aryl Hydrocarbon Receptor

Chien-Ning Hsu, I-Chun Lin, Hong-Ren Yu, Li-Tung Huang, Mao-Meng Tiao, You-Lin Tain

Int J Mol Sci. 2020 Jun; 21(12): 4552. Published online 2020 Jun 26. doi: 10.3390/ijms21124552

PMCID:: PMC7349830

Abstract Article PDF–2.6M

Select item 67705592.

Maternal Exposure to Bisphenol A Combined with High-Fat Diet-Induced Programmed Hypertension in Adult Male Rat Offspring: Effects of Resveratrol

Chien-Ning Hsu, Yu-Ju Lin, You-Lin Tain

Int J Mol Sci. 2019 Sep; 20(18): 4382. Published online 2019 Sep 6. doi: 10.3390/ijms20184382

PMCID:: PMC6770559

Abstract Article PDF–1.6M

Select item 54481723.

Structural hierarchy controlling dimerization and target DNA recognition in the AHR transcriptional complex

Seung-Hyeon Seok, Woojong Lee, Li Jiang, Kaivalya Molugu, Aiping Zheng, Yitong Li, Sanghyun Park, Christopher A. Bradfield, Yongna Xing

Proc Natl Acad Sci U S A. 2017 May 23; 114(21): 5431–5436. Published online 2017 Apr 10. doi: 10.1073/pnas.1617035114

PMCID:: PMC5448172

Abstract Article PDF–1.5M

Select item 53405024.

Targeting Renal Cell Carcinoma with a HIF-2 antagonist

Wenfang Chen, Haley Hill, Alana Christie, Min Soo Kim, Eboni Holloman, Andrea Pavia-Jimenez, Farrah Homayoun, Yuanqing Ma, Nirav Patel, Paul Yell, Guiyang Hao, Qurratulain Yousuf, Allison Joyce, Ivan Pedrosa, Heather Geiger, He Zhang, Jenny Chang, Kevin H. Gardner, Richard K. Bruick, Catherine Reeves, Tae Hyun Hwang, Kevin Courtney, Eugene Frenkel, Xiankai Sun, Naseem Zojwalla, Tai Wong, James P. Rizzi, Eli M. Wallace, John A. Josey, Yang Xie, Xian-Jin Xie, Payal Kapur, Renée M. McKay, James Brugarolas

Nature. Author manuscript; available in PMC 2017 May 3.

Published in final edited form as: Nature. 2016 Nov 3; 539(7627): 112–117. Published online 2016 Sep 5. doi: 10.1038/nature19796

PMCID:: PMC5340502

Abstract Article PDF–5.5M

Select item 51118845.

NPAS1-ARNT and NPAS3-ARNT crystal structures implicate the bHLH-PAS family as multi-ligand binding transcription factors

Dalei Wu, Xiaoyu Su, Nalini Potluri, Youngchang Kim, Fraydoon Rastinejad

eLife. 2016; 5: e18790. Published online 2016 Oct 26. doi: 10.7554/eLife.18790

PMCID:: PMC5111884

Abstract Article PDF–6.6M

Select item 38938216.

Diet-relevant phytochemical intake affects the cardiac AhR and nrf2 transcriptome and reduces heart failure in hypertensive rats

E Mitchell Seymour, Maurice R. Bennink, Steven F. Bolling

J Nutr Biochem. Author manuscript; available in PMC 2014 Sep 1.

Published in final edited form as: J Nutr Biochem. 2013 Sep; 24(9): 1580–1586. Published online 2013 Mar 22. doi: 10.1016/j.jnutbio.2013.01.008

PMCID:: PMC3893821

Abstract Article PDF–387K

Select item 38119027.

Structure and Dimerization Properties of the Aryl Hydrocarbon Receptor PAS-A Domain

Dalei Wu, Nalini Potluri, Youngchang Kim, Fraydoon Rastinejad

Mol Cell Biol. 2013 Nov; 33(21): 4346–4356. doi: 10.1128/MCB.00698-13

PMCID:: PMC3811902

Abstract Article PDF–3.9M

Select item 35620008.

2,3,7,8-Tetrachlorodibenzo-p-dioxin poly(ADP-ribose) polymerase (TiPARP, ARTD14) is a mono-ADP-ribosyltransferase and repressor of aryl hydrocarbon receptor transactivation

Laura MacPherson, Laura Tamblyn, Sharanya Rajendra, Fernando Bralha, J. Peter McPherson, Jason Matthews

Nucleic Acids Res. 2013 Feb; 41(3): 1604–1621. Published online 2012 Dec 25. doi: 10.1093/nar/gks1337

PMCID:: PMC3562000

Abstract Article PDF–6.4M

Select item 34019129.

HIF1α and HIF2α: sibling rivalry in hypoxic tumor growth and progression

Brian Keith, Randall S. Johnson, M. Celeste Simon

Nat Rev Cancer. Author manuscript; available in PMC 2012 Jul 23.

Published in final edited form as: Nat Rev Cancer. 2011 Dec 15; 12(1): 9–22. Published online 2011 Dec 15. doi: 10.1038/nrc3183

PMCID:: PMC3401912

Abstract Article PDF–1.9M

Select item 339126010.

MicroRNA 107 Partly Inhibits Endothelial Progenitor Cells Differentiation via HIF-1β

Shu Meng, JiaTian Cao, LianSheng Wang, Qing Zhou, YiGang Li, ChengXing Shen, XiaoPing Zhang, ChangQian Wang

PLoS One. 2012; 7(7): e40323. Published online 2012 Jul 6. doi: 10.1371/journal.pone.0040323

PMCID:: PMC3391260

Abstract Article PDF–1.2M

Select item 317805911.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 302070812.

Aryl Hydrocarbon Receptor Nuclear Translocator/Hypoxia-inducible Factor-1β Plays a Critical Role in Maintaining Glucose-stimulated Anaplerosis and Insulin Release from Pancreatic β-Cells

Renjitha Pillai, Peter Huypens, Mei Huang, Stephanie Schaefer, Tanya Sheinin, Shawn D. Wettig, Jamie W. Joseph

J Biol Chem. 2011 Jan 14; 286(2): 1014–1024. Published online 2010 Nov 8. doi: 10.1074/jbc.M110.149062

PMCID:: PMC3020708

Abstract Article PDF–2.8M

Select item 287756013.

Hypoxia-inducible factor-1α regulates β cell function in mouse and human islets

Kim Cheng, Kenneth Ho, Rebecca Stokes, Christopher Scott, Sue Mei Lau, Wayne J. Hawthorne, Philip J. O’Connell, Thomas Loudovaris, Thomas W. Kay, Rohit N. Kulkarni, Terumasa Okada, Xiaohui L. Wang, Sun Hee Yim, Yatrik Shah, Shane T. Grey, Andrew V. Biankin, James G. Kench, D. Ross Laybutt, Frank J. Gonzalez, C. Ronald Kahn, Jenny E. Gunton

J Clin Invest. 2010 Jun 1; 120(6): 2171–2183. Published online 2010 May 3. doi: 10.1172/JCI35846