PMC Links for GEO Profiles (Select 23343884) - PMC

Marcel Morgenstern, Christian D. Peikert, Philipp Lübbert, Ida Suppanz, Cinzia Klemm, Oliver Alka, Conny Steiert, Nataliia Naumenko, Alexander Schendzielorz, Laura Melchionda, Wignand W.D. Mühlhäuser, Bettina Knapp, Jakob D. Busch, Sebastian B. Stiller, Stefan Dannenmaier, Caroline Lindau, Mariya Licheva, Christopher Eickhorst, Riccardo Galbusera, Ralf M. Zerbes, Michael T. Ryan, Claudine Kraft, Vera Kozjak-Pavlovic, Friedel Drepper, Sven Dennerlein, Silke Oeljeklaus, Nikolaus Pfanner, Nils Wiedemann, Bettina Warscheid

Cell Metab. 2021 Dec 7; 33(12): 2464–2483.e18. doi: 10.1016/j.cmet.2021.11.001

PMCID:: PMC8664129

Abstract Article

Select item 69856564.

SHP2 deficiency promotes Staphylococcus aureus pneumonia following influenza infection

Wei Ouyang, Chao Liu, Ying Pan, Yu Han, Liping Yang, Jingyan Xia, Feng Xu

Cell Prolif. 2020 Jan; 53(1): e12721. Published online 2019 Nov 29. doi: 10.1111/cpr.12721

PMCID:: PMC6985656

Abstract Article PDF–1.1M

Select item 68442935.

Noonan syndrome-associated SHP2 mutation differentially modulates the expression of postsynaptic receptors according to developmental maturation

Jun-Young Oh, Sangmyung Rhee, Alcino J Silva, Yong-Seok Lee, Hyong Kyu Kim

Neurosci Lett. Author manuscript; available in PMC 2019 Nov 11.

Published in final edited form as: Neurosci Lett. 2017 May 10; 649: 41–47. Published online 2017 Mar 31. doi: 10.1016/j.neulet.2017.03.036

PMCID:: PMC6844293

Abstract Article PDF–1.0M

Select item 66795826.

Tau interacts with SHP2 in neuronal systems and in Alzheimer's disease brains

Yohan Kim, Guanghao Liu, Chad J. Leugers, Joseph D. Mueller, Meghan B. Francis, Marco M. Hefti, Julie A. Schneider, Gloria Lee

J Cell Sci. 2019 Jul 15; 132(14): jcs229054. Published online 2019 Jul 15. doi: 10.1242/jcs.229054

PMCID:: PMC6679582

Abstract Article

Select item 63694457.

Loss of Shp2 Rescues BDNF/TrkB Signaling and Contributes to Improved Retinal Ganglion Cell Neuroprotection

Nitin Chitranshi, Yogita Dheer, Mehdi Mirzaei, Yunqi Wu, Ghasem H. Salekdeh, Mojdeh Abbasi, Veer Gupta, Roshana Vander Wall, Yuyi You, Stuart L. Graham, Vivek Gupta

Mol Ther. 2019 Feb 6; 27(2): 424–441. Published online 2018 Oct 4. doi: 10.1016/j.ymthe.2018.09.019

PMCID:: PMC6369445

Abstract Article PDF–5.7M

Select item 60818628.

Inhibition of Shp2 ameliorates monocrotaline-induced pulmonary arterial hypertension in rats

Yusheng Cheng, Min Yu, Jian Xu, Mengyu He, Hong Wang, Hui Kong, Weiping Xie

BMC Pulm Med. 2018; 18: 130. Published online 2018 Aug 7. doi: 10.1186/s12890-018-0700-y

PMCID:: PMC6081862

Abstract Article PDF–4.6M

Select item 56024059.

Src homology 2 domain–containing phosphotyrosine phosphatase 2 (Shp2) controls surface GluA1 protein in synaptic homeostasis

Bin Zhang, Wen Lu

J Biol Chem. 2017 Sep 15; 292(37): 15481–15488. Published online 2017 Aug 2. doi: 10.1074/jbc.M117.775239

PMCID:: PMC5602405

Abstract Article PDF–1.4M

Select item 500926110.

Increased Activity of Src Homology 2 Domain Containing Phosphotyrosine Phosphatase 2 (Shp2) Regulates Activity-dependent AMPA Receptor Trafficking

Bin Zhang, Yong-lan Du, Wen Lu, Xun-yi Yan, Qian Yang, Wei Yang, Jian-hong Luo

J Biol Chem. 2016 Sep 2; 291(36): 18856–18866. Published online 2016 Jul 14. doi: 10.1074/jbc.M116.714501

PMCID:: PMC5009261

Abstract Article PDF–2.8M

Select item 472449411.

PECAM1 regulates flow-mediated Gab1 tyrosine phosphorylation and signaling

Suowen Xu, Chang Hoon Ha, Weiye Wang, Xiangbin Xu, Meimei Yin, Felix Q. Jin, Michael Mastrangelo, Marina Koroleva, Keigi Fujiwara, Zheng Gen Jin

Cell Signal. Author manuscript; available in PMC 2017 Mar 1.

Published in final edited form as: Cell Signal. 2016 Mar; 28(3): 117–124. Published online 2015 Dec 17. doi: 10.1016/j.cellsig.2015.12.007

PMCID:: PMC4724494

Abstract Article PDF–2.4M

Select item 464345312.

A Common Variant in the PTPN11 Gene Contributes to the Risk of Tetralogy of Fallot

Judith A. Goodship, Darroch Hall, Ana Topf, Chrysovalanto Mamasoula, Helen Griffin, Thahira J. Rahman, Elise Glen, Huay Tan, Julian Palomino Doza, Caroline L. Relton, Jamie Bentham, Shoumo Bhattacharya, Catherine Cosgrove, David Brook, Javier Granados-Riveron, Frances A. Bu’Lock, John O’Sullivan, A. Graham Stuart, Jonathan Parsons, Heather J. Cordell, Bernard Keavney

Circ Cardiovasc Genet. Author manuscript; available in PMC 2015 Nov 13.

Published in final edited form as: Circ Cardiovasc Genet. 2012 Jun; 5(3): 287–292. Published online 2012 Apr 13. doi: 10.1161/CIRCGENETICS.111.962035

PMCID:: PMC4643453

Abstract Article PDF–177K

Select item 442434213.

Protein Kinase A (PKA) Phosphorylation of Shp2 Protein Inhibits Its Phosphatase Activity and Modulates Ligand Specificity

Brian T. Burmeister, Li Wang, Matthew G. Gold, Randal A. Skidgel, John P. O'Bryan, Graeme K. Carnegie

J Biol Chem. 2015 May 8; 290(19): 12058–12067. Published online 2015 Mar 23. doi: 10.1074/jbc.M115.642983

PMCID:: PMC4424342

Abstract Article PDF–1.8M

Select item 430324814.

SHP-2 Mediates Target-Regulated Axonal Termination and NGF-Dependent Neurite Growth in Sympathetic Neurons

Bo Chen, Latanya Hammonds-Odie, Jeanette Perron, Brian A. Masters, John L. Bixby

Dev Biol. Author manuscript; available in PMC 2015 Jan 22.

Published in final edited form as: Dev Biol. 2002 Dec 15; 252(2): 170–187. doi: 10.1006/dbio.2002.0847

PMCID:: PMC4303248

Abstract Article PDF–998K

Select item 417545015.

Significance of SHP-1 and SHP-2 Expression in Human Papillomavirus Infected Condyloma acuminatum and Cervical Cancer

Xiao-hua Tao, Jian-gen Shen, Wei-li Pan, Yu-e Dong, Qun Meng, Kenneth V. Honn, Rongxian Jin

Pathol Oncol Res. Author manuscript; available in PMC 2014 Sep 25.

Published in final edited form as: Pathol Oncol Res. 2008 Dec; 14(4): 365–371. Published online 2008 Jun 10. doi: 10.1007/s12253-008-9065-5

PMCID:: PMC4175450

Abstract Article PDF–481K

Select item 396804016.

Role of the Protein Tyrosine Phosphatase Shp2 in Homeostasis of the Intestinal Epithelium

Hironori Yamashita, Takenori Kotani, Jung-ha Park, Yoji Murata, Hideki Okazawa, Hiroshi Ohnishi, Yonson Ku, Takashi Matozaki

PLoS One. 2014; 9(3): e92904. Published online 2014 Mar 27. doi: 10.1371/journal.pone.0092904

PMCID:: PMC3968040

Abstract Article PDF–1.6M

Select item 389196717.

Shp2-Dependent ERK Signaling Is Essential for Induction of Bergmann Glia and Foliation of the Cerebellum

Kairong Li, Alan W. Leung, Qiuxia Guo, Wentian Yang, James Y. H. Li

J Neurosci. 2014 Jan 15; 34(3): 922–931. doi: 10.1523/JNEUROSCI.3476-13.2014

PMCID:: PMC3891967

Abstract Article PDF–8.2M

Select item 368997518.

New Approaches to Prevent LEOPARD Syndrome-associated Cardiac Hypertrophy by Specifically Targeting Shp2-dependent Signaling

Christine Schramm, Michelle A. Edwards, Maike Krenz

J Biol Chem. 2013 Jun 21; 288(25): 18335–18344. Published online 2013 May 14. doi: 10.1074/jbc.M113.483800

PMCID:: PMC3689975

Abstract Article PDF–2.3M

Select item 365645319.

Megakaryocyte-specific deletion of the protein-tyrosine phosphatases Shp1 and Shp2 causes abnormal megakaryocyte development, platelet production, and function

Alexandra Mazharian, Jun Mori, Ying-Jie Wang, Silke Heising, Benjamin G. Neel, Steve P. Watson, Yotis A. Senis

Blood. 2013 May 16; 121(20): 4205–4220. Prepublished online 2013 Mar 18. doi: 10.1182/blood-2012-08-449272

PMCID:: PMC3656453

Abstract Article

Select item 350940020.

Association of polymorphism of PTPN 11 encoding SHP-2 with gastric atrophy but not gastric cancer in Helicobacter pylori seropositive Chinese population

Jing Jiang, Zhi-Fang Jia, Fei Kong, Mei-Shan Jin, Yin-Ping Wang, Suyan Tian, Jian Suo, Xueyuan Cao

BMC Gastroenterol. 2012; 12: 89. Published online 2012 Jul 12. doi: 10.1186/1471-230X-12-89

PMCID:: PMC3509400

Abstract Article PDF–245K

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