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Select item 113761051.

Molecular Mechanism of ligand-gating and opening of NMDA receptor

Tsung-Han Chou, Max Epstein, Russell G. Fritzemeier, Nicholas S. Akins, Srinu Paladugu, Elijah Z. Ullman, Dennis C. Liotta, Stephen F. Traynelis, Hiro Furukawa

Nature. Author manuscript; available in PMC 2024 Sep 5.

Published in final edited form as: Nature. 2024 Aug; 632(8023): 209–217. Published online 2024 Jul 31. doi: 10.1038/s41586-024-07742-0

PMCID:: PMC11376105

Abstract Article PDF–6.6M

Select item 100753842.

Structural insights into binding of therapeutic channel blockers in NMDA receptors

Tsung-Han Chou, Max Epstein, Kevin Michalski, Eve Fine, Philip C. Biggin, Hiro Furukawa

Nat Struct Mol Biol. Author manuscript; available in PMC 2023 Apr 5.

Published in final edited form as: Nat Struct Mol Biol. 2022 Jun; 29(6): 507–518. Published online 2022 May 30. doi: 10.1038/s41594-022-00772-0

PMCID:: PMC10075384

Abstract Article PDF–5.2M

Select item 80967593.

The NMDA Receptor Subunit (GluN1 and GluN2A) Modulation Following Different Conditions of Cocaine Abstinence in Rat Brain Structures

Irena Smaga, Karolina Wydra, Agata Suder, Małgorzata Frankowska, Marek Sanak, Lucia Caffino, Fabio Fumagalli, Małgorzata Filip

Neurotox Res. 2021; 39(3): 556–565. Published online 2021 Mar 24. doi: 10.1007/s12640-021-00350-0

PMCID:: PMC8096759

Abstract Article PDF–1.6M

Select item 77491704.

Novel use of a chemically modified siRNA for robust and sustainable in vivo gene silencing in the retina

Takazumi Taniguchi, Ken-ichi Endo, Hidetoshi Tanioka, Masaaki Sasaoka, Kei Tashiro, Shigeru Kinoshita, Masaaki Kageyama

Sci Rep. 2020; 10: 22343. Published online 2020 Dec 18. doi: 10.1038/s41598-020-79242-w

PMCID:: PMC7749170

Abstract Article PDF–1.4M

Select item 75960855.

The pathogenic S688Y mutation in the ligand-binding domain of the GluN1 subunit regulates the properties of NMDA receptors

Kristyna Skrenkova, Jae-man Song, Stepan Kortus, Marharyta Kolcheva, Jakub Netolicky, Katarina Hemelikova, Martina Kaniakova, Barbora Hrcka Krausova, Tomas Kucera, Jan Korabecny, Young Ho Suh, Martin Horak

Sci Rep. 2020; 10: 18576. Published online 2020 Oct 29. doi: 10.1038/s41598-020-75646-w

PMCID:: PMC7596085

Abstract Article PDF–2.6M

Select item 70355156.

Conformational spread and dynamics in allostery of NMDA receptors

Ryan J. Durham, Nabina Paudyal, Elisa Carrillo, Nidhi Kaur Bhatia, David M. Maclean, Vladimir Berka, Drew M. Dolino, Alemayehu A. Gorfe, Vasanthi Jayaraman

Proc Natl Acad Sci U S A. 2020 Feb 18; 117(7): 3839–3847. Published online 2020 Feb 3. doi: 10.1073/pnas.1910950117

PMCID:: PMC7035515

Abstract Article PDF–1.5M

Select item 67828307.

Association of AMPA Receptors with a Subset of Glutamate Receptor-Interacting Protein In Vivo

Michael Wyszynski, Juli G. Valtschanoff, Scott Naisbitt, Anthone W. Dunah, Eunjoon Kim, David G. Standaert, Richard Weinberg, Morgan Sheng

J Neurosci. 1999 Aug 1; 19(15): 6528–6537. doi: 10.1523/JNEUROSCI.19-15-06528.1999

PMCID:: PMC6782830

Abstract Article PDF–1.3M

Select item 67824808.

Rescue of Cerebellar Granule Cells from Death in weaver NR1 Double Mutants

Patricia Jensen, D. James Surmeier, Dan Goldowitz

J Neurosci. 1999 Sep 15; 19(18): 7991–7998. doi: 10.1523/JNEUROSCI.19-18-07991.1999

PMCID:: PMC6782480

Abstract Article PDF–815K

Select item 67731369.

NMDA Receptor Activity In Utero Averts Respiratory Depression and Anomalous Long-Term Depression in Newborn Mice

Chi-Sang Poon, Zhongren Zhou, Jean Champagnat

J Neurosci. 2000 May 1; 20(9): RC73. doi: 10.1523/JNEUROSCI.20-09-j0003.2000

PMCID:: PMC6773136

Abstract PDF–118K

Select item 677265210.

Functional Consequences of Reduction in NMDA Receptor Glycine Affinity in Mice Carrying Targeted Point Mutations in the Glycine Binding Site

James N. C. Kew, Anja Koester, Jean-Luc Moreau, Francois Jenck, Abdel-Mouttalib Ouagazzal, Vincent Mutel, J. Grayson Richards, Gerhard Trube, Guenther Fischer, Alexandra Montkowski, Wolfgang Hundt, Rainer K. Reinscheid, Meike Pauly-Evers, John A. Kemp, Horst Bluethmann

J Neurosci. 2000 Jun 1; 20(11): 4037–4049. doi: 10.1523/JNEUROSCI.20-11-04037.2000

PMCID:: PMC6772652

Abstract Article PDF–731K

Select item 676385011.

An NMDA Receptor Signaling Complex with Protein Phosphatase 2A

Shing Fai Chan, Nikolaus J. Sucher

J Neurosci. 2001 Oct 15; 21(20): 7985–7992. doi: 10.1523/JNEUROSCI.21-20-07985.2001

PMCID:: PMC6763850

Abstract Article PDF–350K

Select item 676223512.

Assembly with the NR1 Subunit Is Required for Surface Expression of NR3A-Containing NMDA Receptors

Isabel Pérez-Otaño, Christine T. Schulteis, Anis Contractor, Stuart A. Lipton, James S. Trimmer, Nikolaus J. Sucher, Stephen F. Heinemann

J Neurosci. 2001 Feb 15; 21(4): 1228–1237. doi: 10.1523/JNEUROSCI.21-04-01228.2001

PMCID:: PMC6762235

Abstract Article PDF–730K

Select item 674200413.

Absence of Whisker-Related Pattern Formation in Mice with NMDA Receptors Lacking Coincidence Detection Properties and Calcium Signaling

York Rudhard, Matthias Kneussel, Mohammed A. Nassar, Georg F. Rast, Alexander J. Annala, Philip E. Chen, Cezar M. Tigaret, Isabel Dean, Juergen Roes, Alasdair J. Gibb, Stephen P. Hunt, Ralf Schoepfer

J Neurosci. 2003 Mar 15; 23(6): 2323–2332. doi: 10.1523/JNEUROSCI.23-06-02323.2003

PMCID:: PMC6742004

Abstract Article PDF–551K

Select item 674120214.

A Conditional Deletion of the NR1 Subunit of the NMDA Receptor in Adult Spinal Cord Dorsal Horn Reduces NMDA Currents and Injury-Induced Pain

Samantha M. South, Tatsuro Kohno, Brian K. Kaspar, Deborah Hegarty, Bryce Vissel, Carrie T. Drake, Megumi Ohata, Shirzad Jenab, Andreas W. Sailer, Shelle Malkmus, Takashi Masuyama, Philip Horner, Johanna Bogulavsky, Fred H. Gage, Tony L. Yaksh, Clifford J. Woolf, Stephen F. Heinemann, Charles E. Inturrisi

J Neurosci. 2003 Jun 15; 23(12): 5031–5040. doi: 10.1523/JNEUROSCI.23-12-05031.2003

PMCID:: PMC6741202

Abstract Article PDF–690K

Select item 674110215.

Focal Adhesion Kinase Is Required, But Not Sufficient, for the Induction of Long-Term Potentiation in Dentate Gyrus Neurons In Vivo

Ying C. Yang, Yun L. Ma, Shau K. Chen, Cheng W. Wang, Eminy H. Y. Lee

J Neurosci. 2003 May 15; 23(10): 4072–4080. doi: 10.1523/JNEUROSCI.23-10-04072.2003

PMCID:: PMC6741102

Abstract Article PDF–458K

Select item 674098816.

Intracellular Domains of NMDA Receptor Subtypes Are Determinants for Long-Term Potentiation Induction

Georg Köhr, Vidar Jensen, Helmut J. Koester, Andre L. A. Mihaljevic, Jo K. Utvik, Ane Kvello, Ole P. Ottersen, Peter H. Seeburg, Rolf Sprengel, Øivind Hvalby

J Neurosci. 2003 Nov 26; 23(34): 10791–10799. doi: 10.1523/JNEUROSCI.23-34-10791.2003

PMCID:: PMC6740988

Abstract Article PDF–323K

Select item 674073717.

Impaired NMDA Receptor-Mediated Postsynaptic Function and Blunted NMDA Receptor-Dependent Persistent Pain in Mice Lacking Postsynaptic Density-93 Protein

Yuan-Xiang Tao, Gavin Rumbaugh, Guo-Du Wang, Ronald S. Petralia, Chengshui Zhao, Frederick W. Kauer, Feng Tao, Min Zhuo, Robert J. Wenthold, Srinivasa N. Raja, Richard L. Huganir, David S. Bredt, Roger A. Johns

J Neurosci. 2003 Jul 30; 23(17): 6703–6712. doi: 10.1523/JNEUROSCI.23-17-06703.2003