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Select item 111602241.

Down‐regulation of cyclooxygenase‐2 expression but up‐regulation of cyclooxygenase‐1 in renal carcinomas of the Eker (TSC2 gene mutant) rat model

Toshihiro Okamoto, Atsuko Hara, Okio Hino

Cancer Sci. 2003 Jan; 94(1): 22–25. Published online 2005 Aug 19. doi: 10.1111/j.1349-7006.2003.tb01346.x

PMCID:: PMC11160224

Abstract Article PDF–177K

Select item 99581862.

Cyclooxygenase-2 activates EGFR–ERK1/2 pathway via PGE2-mediated ADAM-17 signaling in testosterone-induced benign prostatic hyperplasia

Mohammed E. Abo-El Fetoh, Maha M. Abdel-Fattah, Wafaa R. Mohamed, Laila A. A. Ramadan, Hassan Afify

Inflammopharmacology. 2023; 31(1): 499–516. Published online 2022 Dec 31. doi: 10.1007/s10787-022-01123-7

PMCID:: PMC9958186

Abstract Article PDF–2.8M

Select item 99165073.

Combination of Radix Astragali and Safflower Promotes Angiogenesis in Rats with Ischemic Stroke via Silencing PTGS2

Shouchao Xu, Jiehong Yang, Haitong Wan, Li Yu, Yu He

Int J Mol Sci. 2023 Feb; 24(3): 2126. Published online 2023 Jan 21. doi: 10.3390/ijms24032126

PMCID:: PMC9916507

Abstract Article PDF–9.8M

Select item 76428914.

COX-2-independent activation of renal (pro)renin receptor contributes to DOCA-salt hypertension in rats

Fei Wang, Ying Sun, Renfei Luo, Xiaohan Lu, Baoxue Yang, Tianxin Yang

Am J Physiol Renal Physiol. 2020 Oct 1; 319(4): F647–F653. Published online 2020 Aug 17. doi: 10.1152/ajprenal.00112.2020

PMCID:: PMC7642891

Abstract Article

Select item 72636335.

Role of GluN2A NMDA receptor in homocysteine-induced prostaglandin E2 release from neurons

Sathyanarayanan Rajagopal, Ashley Anne Fitzgerald, Satya Narayan Deep, Surojit Paul, Ranjana Poddar

J Neurochem. Author manuscript; available in PMC 2020 Jul 1.

Published in final edited form as: J Neurochem. 2019 Jul; 150(1): 44–55. Published online 2019 Jun 20. doi: 10.1111/jnc.14775

PMCID:: PMC7263633

Abstract Article PDF–2.6M

Select item 67295116.

Constitutive Spinal Cyclooxygenase-2 Participates in the Initiation of Tissue Injury-Induced Hyperalgesia

Joseph R. Ghilardi, Camilla I. Svensson, Scott D. Rogers, Tony L. Yaksh, Patrick W. Mantyh

J Neurosci. 2004 Mar 17; 24(11): 2727–2732. doi: 10.1523/JNEUROSCI.5054-03.2004

PMCID:: PMC6729511

Abstract Article PDF–513K

Select item 66726737.

A Cyclooxygenase-2 Inhibitor Ameliorates Behavioral Impairments Induced by Striatal Administration of Epidermal Growth Factor

Makoto Mizuno, Hidekazu Sotoyama, Eri Narita, Hiroki Kawamura, Hisaaki Namba, Yingjun Zheng, Takeyoshi Eda, Hiroyuki Nawa

J Neurosci. 2007 Sep 19; 27(38): 10116–10127. doi: 10.1523/JNEUROSCI.2368-07.2007

PMCID:: PMC6672673

Abstract Article PDF–708K

Select item 66624508.

Cox-2 Negatively Affects the Protective Role of Propofol against Hypoxia/Reoxygenation Induced Cardiomyocytes Apoptosis through Suppressing Akt Signaling

Kangmu Ma, Jiapei Qiu, Mi Zhou, Yang Yang, Xiaofeng Ye

Biomed Res Int. 2019; 2019: 7587451. Published online 2019 Jul 16. doi: 10.1155/2019/7587451

PMCID:: PMC6662450

Abstract Article PDF–1.6M

Select item 65123779.

Anti‐inflammatory effects of low molecular weight heparin derivative in a rat model of carrageenan‐induced pleurisy

Matteo Ceccarelli, Daniele Bani, Lorenzo Cinci, Silvia Nistri, Caterina Uliva, Elena Ragazzo, Alfredo Vannacci, Marco Manoni, Anna Maria Gori, Rosanna Abbate, Gian Franco Gensini, Emanuela Masini

J Cell Mol Med. 2009 Aug; 13(8b): 2704–2712. Published online 2009 Nov 26. doi: 10.1111/j.1582-4934.2008.00658.x

PMCID:: PMC6512377

Abstract Article PDF–878K

Select item 638636310.

Cigarette smoke extracts and cadmium induce COX-2 expression through γ-secretase-mediated p38 MAPK activation in C6 astroglia cells

Hyun Joung Lim, Jung Hyun Park, Chulman Jo, Keejung Yoon, Young Ho Koh

PLoS One. 2019; 14(2): e0212749. Published online 2019 Feb 22. doi: 10.1371/journal.pone.0212749

PMCID:: PMC6386363

Abstract Article PDF–2.0M

Select item 599551211.

COX-2 expression mediated by calcium-TonEBP signaling axis under hyperosmotic conditions serves osmoprotective function in nucleus pulposus cells

Hyowon Choi, Weera Chaiyamongkol, Alexandra C. Doolittle, Zariel I. Johnson, Shilpa S. Gogate, Zachary R. Schoepflin, Irving M. Shapiro, Makarand V. Risbud

J Biol Chem. 2018 Jun 8; 293(23): 8969–8981. Published online 2018 Apr 26. doi: 10.1074/jbc.RA117.001167

PMCID:: PMC5995512

Abstract Article PDF–1.0M

Select item 590255412.

Neuronal SphK1 acetylates COX2 and contributes to pathogenesis in a model of Alzheimer’s Disease

Ju Youn Lee, Seung Hoon Han, Min Hee Park, Bosung Baek, Im-Sook Song, Min-Koo Choi, Yoh Takuwa, Hoon Ryu, Seung Hyun Kim, Xingxuan He, Edward H. Schuchman, Jae-Sung Bae, Hee Kyung Jin

Nat Commun. 2018; 9: 1479. Published online 2018 Apr 16. doi: 10.1038/s41467-018-03674-2

PMCID:: PMC5902554

Abstract Article PDF–2.6M

Select item 586602113.

Hypothyroidism increases cyclooxygenase-2 levels and pro-inflammatory response and decreases cell proliferation and neuroblast differentiation in the hippocampus

Sung Min Nam, Jong Whi Kim, Dae Young Yoo, Hyo Young Jung, Jin Young Chung, Dae Won Kim, In Koo Hwang, Yeo Sung Yoon

Mol Med Rep. 2018 Apr; 17(4): 5782–5788. Published online 2018 Feb 13. doi: 10.3892/mmr.2018.8605

PMCID:: PMC5866021

Abstract Article PDF–1.6M

Select item 584235714.

Cyclooxygenase-2 expression in primary breast cancers predicts dissemination of cancer cells to the bone marrow

Anthony Lucci, Savitri Krishnamurthy, Balraj Singh, Isabelle Bedrosian, Funda Meric-Bernstam, James Reuben, Kristine Broglio, Kailash Mosalpuria, Ashutosh Lodhi, Laura Vincent, Massimo Cristofanilli

Breast Cancer Res Treat. Author manuscript; available in PMC 2018 Mar 8.

Published in final edited form as: Breast Cancer Res Treat. 2009 Sep; 117(1): 61–68. Published online 2008 Jul 29. doi: 10.1007/s10549-008-0135-x

PMCID:: PMC5842357

Abstract Article PDF–259K

Select item 565773715.

Genetic and Histological Alterations Reveal Key Role of Prostaglandin Synthase and Cyclooxygenase 1 and 2 in Traumatic Brain Injury–Induced Neuroinflammation in the Cerebral Cortex of Rats Exposed to Moderate Fluid Percussion Injury

Hideki Shojo, Cesario V. Borlongan, Tadashi Mabuchi

Cell Transplant. 2017 Jul; 26(7): 1301–1313. Published online 2017 Jun 30. doi: 10.1177/0963689717715169

PMCID:: PMC5657737

Abstract Article PDF–1.4M

Select item 562526216.

Arterial stiffness induces remodeling phenotypes in pulmonary artery smooth muscle cells via YAP/TAZ-mediated repression of cyclooxygenase-2

Paul B. Dieffenbach, Christina Mallarino Haeger, Anna Maria F. Coronata, Kyoung Moo Choi, Xaralabos Varelas, Daniel J. Tschumperlin, Laura E. Fredenburgh

Am J Physiol Lung Cell Mol Physiol. 2017 Sep 1; 313(3): L628–L647. Published online 2017 Jun 22. doi: 10.1152/ajplung.00173.2017