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Select item 109023231.

NEDD4-2 and the CLC-2 channel regulate neuronal excitability in the pathogenesis of mesial temporal lobe epilepsy

Yuting Liu, Haiyan Yang, Rongrong Zeng, Lu He, Ting Xiao, Xiaomei Peng, Zhuo Kuang, Liwen Wu

Sci Rep. 2024; 14: 4835. Published online 2024 Feb 28. doi: 10.1038/s41598-024-52399-4

PMCID:: PMC10902323

Abstract Article PDF–3.7M

Select item 100790182.

Identification of Ndfip1 as a novel negative regulator for spatial memory formation associated with increased ubiquitination of Beclin 1 and PTEN

Wei-Lun Hsu, Yun-Li Ma, Yan-Chu Chen, Yen-Chen Liu, Kuang-Min Cheng, Eminy H. Y. Lee

PLoS One. 2023; 18(4): e0283908. Published online 2023 Apr 6. doi: 10.1371/journal.pone.0283908

PMCID:: PMC10079018

Abstract Article PDF–2.5M

Select item 90978393.

NEDD4 attenuates phosgene‐induced acute lung injury through the inhibition of Notch1 activation

Yiru Shao, Zhifeng Jiang, Daikun He, Jie Shen

J Cell Mol Med. 2022 May; 26(10): 2831–2840. Published online 2022 Mar 31. doi: 10.1111/jcmm.17296

PMCID:: PMC9097839

Abstract Article PDF–12M

Select item 83289974.

Aagab acts as a novel regulator of NEDD4-1-mediated Pten nuclear translocation to promote neurological recovery following hypoxic-ischemic brain damage

Chunfang Dai, Bin Wu, Yuxin Chen, Xiaohuan Li, Yanrui Bai, Yehong Du, Yayan Pang, Yu Tian Wang, Zhifang Dong

Cell Death Differ. 2021 Aug; 28(8): 2367–2384. Published online 2021 Mar 12. doi: 10.1038/s41418-021-00757-4

PMCID:: PMC8328997

Abstract Article PDF–4.4M

Select item 66737935.

RNA Interference Screen Reveals an Essential Role of Nedd4–2 in Dopamine Transporter Ubiquitination and Endocytosis

Tatiana Sorkina, Manuel Miranda, Kalen R. Dionne, Brian R. Hoover, Nancy R. Zahniser, Alexander Sorkin

J Neurosci. 2006 Aug 2; 26(31): 8195–8205. doi: 10.1523/JNEUROSCI.1301-06.2006

PMCID:: PMC6673793

Abstract Article PDF–711K

Select item 63636306.

Microarray analysis and functional characterization revealed NEDD4-mediated cardiomyocyte autophagy induced by angiotensin II

Ying Gu, Fan Yang, Yongchao Yu, Jianxia Meng, Yang Li, Ruming Xu, Yang Liu, Yuchen Xiao, Zhiyun Xu, Liping Ma, Guokun Wang

Cell Stress Chaperones. 2019 Jan; 24(1): 203–212. Published online 2019 Jan 10. doi: 10.1007/s12192-018-00957-x

PMCID:: PMC6363630

Abstract Article PDF–3.8M

Select item 52432217.

The role of Nedd4-1 WW domains in binding and regulating human organic anion transporter 1

Da Xu, Haoxun Wang, Carol Gardner, Zui Pan, Ping L. Zhang, Jinghui Zhang, Guofeng You

Am J Physiol Renal Physiol. 2016 Aug 1; 311(2): F320–F329. Published online 2016 May 25. doi: 10.1152/ajprenal.00153.2016

PMCID:: PMC5243221

Abstract Article

Select item 51371498.

Ubiquitin Ligase NEDD4 Regulates PPARγ Stability and Adipocyte Differentiation in 3T3-L1 Cells

Jing Jing Li, Ruishan Wang, Rati Lama, Xinjiang Wang, Z. Elizabeth Floyd, Edwards A. Park, Francesca-Fang Liao

Sci Rep. 2016; 6: 38550. Published online 2016 Dec 5. doi: 10.1038/srep38550

PMCID:: PMC5137149

Abstract Article PDF–1.8M

Select item 48448339.

The multidrug resistance pump ABCB1 is a substrate for the ubiquitin ligase NEDD4-1

Begum G. Akkaya, Joseph K. Zolnerciks, Tasha K. Ritchie, Bjoern Bauer, Anika M.S. Hartz, James A. Sullivan, Kenneth J. Linton

Mol Membr Biol. Author manuscript; available in PMC 2016 May 26.

Published in final edited form as: Mol Membr Biol. 2015; 32(2): 39–45. Published online 2015 May 26. doi: 10.3109/09687688.2015.1023378

PMCID:: PMC4844833

Abstract Article PDF–647K

Select item 481719010.

Structural Studies of the Nedd4 WW Domains and Their Selectivity for the Connexin43 (Cx43) Carboxyl Terminus

Gaelle Spagnol, Fabien Kieken, Jennifer L. Kopanic, Hanjun Li, Sydney Zach, Kelly L. Stauch, Rosslyn Grosely, Paul L. Sorgen

J Biol Chem. 2016 Apr 1; 291(14): 7637–7650. Published online 2016 Feb 3. doi: 10.1074/jbc.M115.701417

PMCID:: PMC4817190

Abstract Article PDF–3.1M

Select item 475615111.

Histone Modification of Nedd4 Ubiquitin Ligase Controls the Loss of AMPA Receptors and Cognitive Impairment Induced by Repeated Stress

Jing Wei, Zhe Xiong, Janine B. Lee, Jia Cheng, Lara J. Duffney, Emmanuel Matas, Zhen Yan

J Neurosci. 2016 Feb 17; 36(7): 2119–2130. doi: 10.1523/JNEUROSCI.3056-15.2016

PMCID:: PMC4756151

Abstract Article PDF–2.7M

Select item 453236512.

E3 Ubiquitin Ligase NEDD4 Promotes Influenza Virus Infection by Decreasing Levels of the Antiviral Protein IFITM3

Nicholas M. Chesarino, Temet M. McMichael, Jacob S. Yount

PLoS Pathog. 2015 Aug; 11(8): e1005095. Published online 2015 Aug 11. doi: 10.1371/journal.ppat.1005095

PMCID:: PMC4532365

Abstract Article PDF–3.0M

Select item 445253813.

Dlg3 Trafficking and Apical Tight Junction Formation Is Regulated by Nedd4 and Nedd4-2 E3 Ubiquitin Ligases

Claude A. Van Campenhout, Andrea Eitelhuber, Christian J. Gloeckner, Patrizia Giallonardo, Moritz Gegg, Heide Oller, Seth G.N. Grant, Daniel Krappmann, Marius Ueffing, Heiko Lickert

Dev Cell. 2011 Sep 13; 21(3): 479–491. doi: 10.1016/j.devcel.2011.08.003

PMCID:: PMC4452538

Abstract Article

Select item 435813414.

Nedd4 Family Interacting Protein 1 (Ndfip1) Is Required for Ubiquitination and Nuclear Trafficking of BRCA1-associated ATM Activator 1 (BRAT1) during the DNA Damage Response

Ley-Hian Low, Yuh-Lit Chow, Yijia Li, Choo-Peng Goh, Ulrich Putz, John Silke, Toru Ouchi, Jason Howitt, Seong-Seng Tan

J Biol Chem. 2015 Mar 13; 290(11): 7141–7150. Published online 2015 Jan 28. doi: 10.1074/jbc.M114.613687

PMCID:: PMC4358134

Abstract Article PDF–2.5M

Select item 426109215.

Synaptic Strength Is Bidirectionally Controlled by Opposing Activity-Dependent Regulation of Nedd4-1 and USP8

Samantha L. Scudder, Marisa S. Goo, Anna E. Cartier, Alice Molteni, Lindsay A. Schwarz, Rebecca Wright, Gentry N. Patrick

J Neurosci. 2014 Dec 10; 34(50): 16637–16649. doi: 10.1523/JNEUROSCI.2452-14.2014

PMCID:: PMC4261092

Abstract Article PDF–3.6M

Select item 398892416.

Enhanced ubiquitin-dependent degradation by Nedd4 protects against α-synuclein accumulation and toxicity in animal models of Parkinson's disease

Sian E. Davies, Penelope J. Hallett, Thomas Moens, Gaynor Smith, Emily Mangano, Hyoung Tae Kim, Alfred L. Goldberg, Ji-Long Liu, Ole Isacson, George K. Tofaris

Neurobiol Dis. 2014 Apr; 64(100): 79–87. doi: 10.1016/j.nbd.2013.12.011

PMCID:: PMC3988924

Abstract Article PDF–1.2M

Select item 385507917.

Nedd4 is a Specific E3 Ubiquitin Ligase for the NMDA Receptor Subunit GluN2D

Vivek Gautam, Jonathan C. Trinidad, Ronald A. Rimerman, Blaise M. Costa, Alma L. Burlingame, Daniel T. Monaghan

Neuropharmacology. Author manuscript; available in PMC 2014 Nov 1.

Published in final edited form as: Neuropharmacology. 2013 Nov; 74: 10.1016/j.neuropharm.2013.04.035. Published online 2013 Apr 29. doi: 10.1016/j.neuropharm.2013.04.035

PMCID:: PMC3855079

Abstract Article PDF–3.5M

Select item 382735818.

Lipopolysaccharide Induces Degradation of Connexin43 in Rat Astrocytes via the Ubiquitin-Proteasome Proteolytic Pathway

Chih-Kai Liao, Chung-Jiuan Jeng, Hwai-Shi Wang, Shu-Huei Wang, Jiahn-Chun Wu

PLoS One. 2013; 8(11): e79350. Published online 2013 Nov 13. doi: 10.1371/journal.pone.0079350

PMCID:: PMC3827358

Abstract Article PDF–4.6M

Select item 377350519.

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

Simona Principe, E. Ellen Jones, Yunee Kim, Ankit Sinha, Julius O. Nyalwidhe, Jasmin Brooks, O. John Semmes, Dean A. Troyer, Raymond S. Lance, Thomas Kislinger, Richard R. Drake

Proteomics. Author manuscript; available in PMC 2014 May 1.

Published in final edited form as: Proteomics. 2013 May; 13(0): 1667–1671. Published online 2013 Apr 23. doi: 10.1002/pmic.201200561