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Select item 74417441.

Nkx2–5 Regulates the Proliferation and Migration of H9c2 Cells

Hongshu Wang, Yong Liu, Shen Han, Yunfeng Zi, Yayong Zhang, Ruize Kong, Zu Liu, Zhibin Cai, Chongbin Zhong, Wei Liu, Lifeng Li, Lihong Jiang

Med Sci Monit. 2020; 26: e925388-1–e925388-16. Prepublished online 2020 Aug 5. Published online 2020 Aug 11. doi: 10.12659/MSM.925388

PMCID:: PMC7441744

Abstract Article PDF–2.4M

Select item 66297362.

Role of Nkx2.5 in H₂O₂-induced Nsd1 suppression

Xiaoyan Liang, Guoming Chu, Leitong Wang, Guangrui Lai, Yanyan Zhao

Cell Stress Chaperones. 2019 Jul; 24(4): 697–707. Published online 2019 May 18. doi: 10.1007/s12192-019-00995-z

PMCID:: PMC6629736

Abstract Article PDF–1.6M

Select item 50192453.

Familial Atrial Septal Defect and Sudden Cardiac Death: Identification of a Novel NKX2‐5 Mutation and a Review of the Literature

Sabrina Gade Ellesøe, Morten Munk Johansen, Jesper Vandborg Bjerre, Vibeke Elisabeth Hjortdal, Søren Brunak, Lars Allan Larsen

Congenit Heart Dis. 2016 May-Jun; 11(3): 283–290. Published online 2015 Dec 18. doi: 10.1111/chd.12317

PMCID:: PMC5019245

Abstract Article PDF–196K

Select item 48891604.

Variants of Transient Receptor Potential Melastatin Member 4 in Childhood Atrioventricular Block

Ninda Syam, Stéphanie Chatel, Lijo Cherian Ozhathil, Valentin Sottas, Jean‐Sébastien Rougier, Alban Baruteau, Estelle Baron, Mohamed‐Yassine Amarouch, Xavier Daumy, Vincent Probst, Jean‐Jacques Schott, Hugues Abriel

J Am Heart Assoc. 2016 May; 5(5): e001625. Published online 2016 May 20. doi: 10.1161/JAHA.114.001625

PMCID:: PMC4889160

Abstract Article PDF–1.9M

Select item 43515245.

NKX2-5 Mutations in an Inbred Consanguineous Population: Genetic and Phenotypic Diversity

Ossama K. Abou Hassan, Akl C. Fahed, Manal Batrawi, Mariam Arabi, Marwan M. Refaat, Steven R. DePalma, J. G. Seidman, Christine E. Seidman, Fadi F. Bitar, Georges M. Nemer

Sci Rep. 2015; 5: 8848. Published online 2015 Mar 6. doi: 10.1038/srep08848

PMCID:: PMC4351524

Abstract Article PDF–647K

Select item 41409556.

A mouse model of human congenital heart disease: high incidence of diverse cardiac anomalies and ventricular noncompaction produced by heterozygous Nkx2-5 homeodomain missense mutation

Hassan Ashraf, Lagnajeet Pradhan, Eileen I. Chang, Ryota Terada, Nicole J. Ryan, Laura E. Briggs, Rajib Chowdhury, Miguel A. Zárate, Yukiko Sugi, Hyun-Joo Nam, D. Woodrow Benson, Robert H. Anderson, Hideko Kasahara

Circ Cardiovasc Genet. Author manuscript; available in PMC 2015 Aug 1.

Published in final edited form as: Circ Cardiovasc Genet. 2014 Aug; 7(4): 423–433. Published online 2014 Jul 15. doi: 10.1161/CIRCGENETICS.113.000281

PMCID:: PMC4140955

Abstract Article PDF–3.3M

Select item 35322057.

The Ambiguous Role of NKX2-5 Mutations in Thyroid Dysgenesis

Klaartje van Engelen, Mathilda T. M. Mommersteeg, Marieke J. H. Baars, Jan Lam, Aho Ilgun, A. S. Paul van Trotsenburg, Anne M. J. B. Smets, Vincent M. Christoffels, Barbara J. M. Mulder, Alex V. Postma

PLoS One. 2012; 7(12): e52685. Published online 2012 Dec 28. doi: 10.1371/journal.pone.0052685

PMCID:: PMC3532205

Abstract Article PDF–263K

Select item 34480078.

Crystal Structure of the Human NKX2.5 Homeodomain in Complex with DNA Target

Lagnajeet Pradhan, Caroli Genis, Peyton Scone, Ellen O. Weinberg, Hideko Kasahara, Hyun-Joo Nam

Biochemistry. Author manuscript; available in PMC 2012 Sep 21.

Published in final edited form as: Biochemistry. 2012 Aug 14; 51(32): 6312–6319. Published online 2012 Aug 3. doi: 10.1021/bi300849c

PMCID:: PMC3448007

Abstract Article PDF–1.9M

Select item 33565059.

Congenital Asplenia in Mice and Humans with Mutations in a Pbx/Nkx2-5/p15 Module

Matthew Koss, Alexandre Bolze, Andrea Brendolan, Matilde Saggese, Terence D. Capellini, Ekaterina Bojilova, Bertrand Boisson, Owen W.J. Prall, David Elliott, Mark Solloway, Elisa Lenti, Chisa Hidaka, Ching-Pin Chang, Nizar Mahlaoui, Richard P. Harvey, Jean-Laurent Casanova, Licia Selleri

Dev Cell. Author manuscript; available in PMC 2013 May 15.

Published in final edited form as: Dev Cell. 2012 May 15; 22(5): 913–926. Published online 2012 May 3. doi: 10.1016/j.devcel.2012.02.009

PMCID:: PMC3356505

Abstract Article PDF–6.8M

Select item 321633910.

Tinman/Nkx2-5 acts via miR-1 and upstream of Cdc42 to regulate heart function across species

Li Qian, Joshua D. Wythe, Jiandong Liu, Jerome Cartry, Georg Vogler, Bhagyalaxmi Mohapatra, Robyn T. Otway, Yu Huang, Isabelle N. King, Marjorie Maillet, Yi Zheng, Timothy Crawley, Ouarda Taghli-Lamallem, Christopher Semsarian, Sally Dunwoodie, David Winlaw, Richard P. Harvey, Diane Fatkin, Jeffrey A. Towbin, Jeffery D. Molkentin, Deepak Srivastava, Karen Ocorr, Benoit G. Bruneau, Rolf Bodmer

J Cell Biol. 2011 Jun 27; 193(7): 1181–1196. doi: 10.1083/jcb.201006114

PMCID:: PMC3216339

Abstract Article PDF–3.6M

Select item 317805911.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 317148212.

Complex SUMO-1 Regulation of Cardiac Transcription Factor Nkx2-5

Mauro W. Costa, Stella Lee, Milena B. Furtado, Li Xin, Duncan B. Sparrow, Camila G. Martinez, Sally L. Dunwoodie, Eleonora Kurtenbach, Tim Mohun, Nadia Rosenthal, Richard P. Harvey

PLoS One. 2011; 6(9): e24812. Published online 2011 Sep 12. doi: 10.1371/journal.pone.0024812

PMCID:: PMC3171482

Abstract Article PDF–1.0M

Select item 304067813.

The Cardiac Transcription Network Modulated by Gata4, Mef2a, Nkx2.5, Srf, Histone Modifications, and MicroRNAs

Jenny Schlesinger, Markus Schueler, Marcel Grunert, Jenny J. Fischer, Qin Zhang, Tammo Krueger, Martin Lange, Martje Tönjes, Ilona Dunkel, Silke R. Sperling

PLoS Genet. 2011 Feb; 7(2): e1001313. Published online 2011 Feb 17. doi: 10.1371/journal.pgen.1001313

PMCID:: PMC3040678

Abstract Article PDF–2.2M

Select item 292250314.

Foxp1 coordinates cardiomyocyte proliferation through both cell-autonomous and nonautonomous mechanisms

Yuzhen Zhang, Shanru Li, Lijun Yuan, Ying Tian, Joel Weidenfeld, Jifu Yang, Feiyan Liu, Ann L. Chokas, Edward E. Morrisey

Genes Dev. 2010 Aug 15; 24(16): 1746–1757. doi: 10.1101/gad.1929210

PMCID:: PMC2922503

Abstract Article PDF–2.1M

Select item 289755315.

Pref-1 Interacts with Fibronectin To Inhibit Adipocyte Differentiation

Yuhui Wang, Ling Zhao, Cynthia Smas, Hei Sook Sul

Mol Cell Biol. 2010 Jul; 30(14): 3480–3492. Published online 2010 May 10. doi: 10.1128/MCB.00057-10

PMCID:: PMC2897553

Abstract Article PDF–5.1M

Select item 282298316.

Nkx2.5/Csx Represses Myofibroblast Differentiation

Biao Hu, Yue Ming Wu, Zhe Wu, Sem H. Phan

Am J Respir Cell Mol Biol. 2010 Feb; 42(2): 218–226. Published online 2009 Apr 24. doi: 10.1165/rcmb.2008-0404OC

PMCID:: PMC2822983

Abstract Article PDF–824K

Select item 277500417.

Histone deacetylases facilitate sodium/calcium exchanger up-regulation in adult cardiomyocytes

Sangeetha Chandrasekaran, Richard E. Peterson, Santhosh K. Mani, Benjamin Addy, Avery L. Buchholz, Lin Xu, Thirumagal Thiyagarajan, Harinath Kasiganesan, Christine B. Kern, Donald R. Menick

FASEB J. 2009 Nov; 23(11): 3851–3864. doi: 10.1096/fj.09-132415

PMCID:: PMC2775004

Abstract Article

Select item 276920318.

miR-145 and miR-143 Regulate Smooth Muscle Cell Fate Decisions

Kimberly R. Cordes, Neil T. Sheehy, Mark White, Emily Berry, Sarah U. Morton, Alecia N. Muth, Ting-Hein Lee, Joseph M. Miano, Kathryn N. Ivey, Deepak Srivastava

Nature. Author manuscript; available in PMC 2010 Feb 7.

Published in final edited form as: Nature. 2009 Aug 6; 460(7256): 705–710. Published online 2009 Jul 5. doi: 10.1038/nature08195

PMCID:: PMC2769203

Abstract Article PDF–2.2M

Select item 273392719.

Slow progressive conduction and contraction defects in loss of Nkx2–5 mice after cardiomyocyte terminal differentiation

Morihiko Takeda, Laura E. Briggs, Hiroko Wakimoto, Melissa H. Marks, Sonisha A. Warren, Jonathan T. Lu, Ellen O. Weinberg, Keith D. Robertson, Kenneth R. Chien, Hideko Kasahara

Lab Invest. Author manuscript; available in PMC 2010 Mar 1.

Published in final edited form as: Lab Invest. 2009 Sep; 89(9): 983–993. Published online 2009 Jun 22. doi: 10.1038/labinvest.2009.59

PMCID:: PMC2733927

Abstract Article PDF–1.8M

Select item 268463720.

NKX2-5 Regulates the Expression of β-Catenin and GATA4 in Ventricular Myocytes

Ali M. Riazi, Jun K. Takeuchi, Lisa K. Hornberger, Syed Hassan Zaidi, Fariba Amini, John Coles, Benoit G. Bruneau, Glen S. Van Arsdell

PLoS One. 2009; 4(5): e5698. Published online 2009 May 28. doi: 10.1371/journal.pone.0005698

PMCID:: PMC2684637

Abstract Article PDF–1000K

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