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Select item 63707131.

Neuroblastoma RAS Viral Oncogene Homolog (NRAS) Is a Novel Prognostic Marker and Contributes to Sorafenib Resistance in Hepatocellular Carcinoma

Peter Dietrich, Anne Gaza, Laura Wormser, Valerie Fritz, Claus Hellerbrand, Anja Katrin Bosserhoff

Neoplasia. 2019 Mar; 21(3): 257–268. Published online 2019 Jan 25. doi: 10.1016/j.neo.2018.11.011

PMCID:: PMC6370713

Abstract Article PDF–4.1M

Select item 56256682.

Tumour mutation status and sites of metastasis in patients with cutaneous melanoma

Nikki R Adler, Rory Wolfe, John W Kelly, Andrew Haydon, Grant A McArthur, Catriona A McLean, Victoria J Mar

Br J Cancer. 2017 Sep 26; 117(7): 1026–1035. Published online 2017 Aug 8. doi: 10.1038/bjc.2017.254

PMCID:: PMC5625668

Abstract Article PDF–275K

Select item 53473943.

The ability of endogenous Nras oncogenes to initiate leukemia is codon-dependent

Guangyao Kong, Yuan-I Chang, Xiaona You, Erik A. Ranheim, Yun Zhou, Christin E. Burd, Jing Zhang

Leukemia. Author manuscript; available in PMC 2017 Mar 13.

Published in final edited form as: Leukemia. 2016 Sep; 30(9): 1935–1938. Published online 2016 Apr 25. doi: 10.1038/leu.2016.89

PMCID:: PMC5347394

Article PDF–361K

Select item 48727914.

Comparison of liver oncogenic potential among human RAS isoforms

Sook In Chung, Hyuk Moon, Hye-Lim Ju, Dae Yeong Kim, Kyung Joo Cho, Silvia Ribback, Frank Dombrowski, Diego F. Calvisi, Simon Weonsang Ro

Oncotarget. 2016 Feb 9; 7(6): 7354–7366. Published online 2016 Jan 18. doi: 10.18632/oncotarget.6931

PMCID:: PMC4872791

Abstract Article PDF–8.6M

Select item 45210335.

Deficiency of β Common Receptor Moderately Attenuates the Progression of Myeloproliferative Neoplasm in Nras^G12D/+ Mice

Jingfang Zhang, Erik A. Ranheim, Juan Du, Yangang Liu, Jinyong Wang, Guangyao Kong, Jing Zhang

J Biol Chem. 2015 Jul 31; 290(31): 19093–19103. Published online 2015 Jun 16. doi: 10.1074/jbc.M115.653154

PMCID:: PMC4521033

Abstract Article PDF–3.3M

Select item 42309266.

Clonal Architectures and Driver Mutations in Metastatic Melanomas

Li Ding, Minjung Kim, Krishna L. Kanchi, Nathan D. Dees, Charles Lu, Malachi Griffith, David Fenstermacher, Hyeran Sung, Christopher A. Miller, Brian Goetz, Michael C. Wendl, Obi Griffith, Lynn A. Cornelius, Gerald P. Linette, Joshua F. McMichael, Vernon K. Sondak, Ryan C. Fields, Timothy J. Ley, James J. Mulé, Richard K. Wilson, Jeffrey S. Weber

PLoS One. 2014; 9(11): e111153. Published online 2014 Nov 13. doi: 10.1371/journal.pone.0111153

PMCID:: PMC4230926

Abstract Article PDF–3.1M

Select item 41234257.

Mutation of NRAS but not KRAS significantly reduces myeloma sensitivity to single-agent bortezomib therapy

George Mulligan, David I. Lichter, Alessandra Di Bacco, Stephen J. Blakemore, Allison Berger, Erik Koenig, Hugues Bernard, William Trepicchio, Bin Li, Rachel Neuwirth, Nibedita Chattopadhyay, Joseph B. Bolen, Andrew J. Dorner, Helgi van de Velde, Deborah Ricci, Sundar Jagannath, James R. Berenson, Paul G. Richardson, Edward A. Stadtmauer, Robert Z. Orlowski, Sagar Lonial, Kenneth C. Anderson, Pieter Sonneveld, Jesús F. San Miguel, Dixie-Lee Esseltine, Matthew Schu

Blood. 2014 Jan 30; 123(5): 632–639. Prepublished online 2013 Dec 11. doi: 10.1182/blood-2013-05-504340

PMCID:: PMC4123425

Abstract Article

Select item 39677198.

NRAS Mutations with Low Allele Burden have Independent Prognostic Significance for Patients with Lower Risk Myelodysplastic Syndromes

Derek M Murphy, Rafael Bejar, Kristen Stevenson, Donna Neuberg, Yanggu Shi, Courtney Cubrich, Katherine Richardson, Phil Eastlake, Guillermo Garcia-Manero, Hagop Kantarjian, Benjamin L. Ebert, G. Mike Makrigiorgos

Leukemia. Author manuscript; available in PMC 2014 Apr 1.

Published in final edited form as: Leukemia. 2013 Oct; 27(10): 2077–2081. Published online 2013 May 27. doi: 10.1038/leu.2013.160

PMCID:: PMC3967719

Article PDF–880K

Select item 38505979.

An Increase in N-Ras Expression is Associated with Development of Hormone Refractory Prostate Cancer in a Subset of Patients

Pamela Traynor, Liane M. McGlynn, Rono Mukhergee, Samuel J. S. Grimsley, John M. S. Bartlett, Joanne Edwards

Dis Markers. 2008; 24(3): 157–165. Published online 2008 Mar 4. doi: 10.1155/2008/918087

PMCID:: PMC3850597

Summary PDF–280K

Select item 363890510.

MicroRNA-146a is a therapeutic target and biomarker for peripartum cardiomyopathy

Julie Halkein, Sebastien P. Tabruyn, Melanie Ricke-Hoch, Arash Haghikia, Ngoc-Quynh-Nhu Nguyen, Michaela Scherr, Karolien Castermans, Ludovic Malvaux, Vincent Lambert, Marc Thiry, Karen Sliwa, Agnes Noel, Joseph A. Martial, Denise Hilfiker-Kleiner, Ingrid Struman

J Clin Invest. 2013 May 1; 123(5): 2143–2154. Published online 2013 Apr 24. doi: 10.1172/JCI64365

PMCID:: PMC3638905

Abstract Article PDF–3.8M

Select item 351821911.

KIF14 negatively regulates Rap1a–Radil signaling during breast cancer progression

Syed M. Ahmed, Brigitte L. Thériault, Maruti Uppalapati, Catherine W.N. Chiu, Brenda L. Gallie, Sachdev S. Sidhu, Stéphane Angers

J Cell Biol. 2012 Dec 10; 199(6): 951–967. doi: 10.1083/jcb.201206051

PMCID:: PMC3518219

Abstract Article PDF–3.7M

Select item 331755312.

PAQR10 and PAQR11 mediate Ras signaling in the Golgi apparatus

Ting Jin, Qiurong Ding, Heng Huang, Daqian Xu, Yuhui Jiang, Ben Zhou, Zhenghu Li, Xiaomeng Jiang, Jing He, Weizhong Liu, Yixuan Zhang, Yi Pan, Zhenzhen Wang, Walter G Thomas, Yan Chen

Cell Res. 2012 Apr; 22(4): 661–676. Published online 2011 Oct 4. doi: 10.1038/cr.2011.161

PMCID:: PMC3317553

Abstract Article PDF–1.7M

Select item 326955313.

AKT and N-Ras co-activation in the mouse liver promotes rapid carcinogenesis via mTORC1, FOXM1/SKP2, and c-Myc pathways

Coral Ho, Chunmei Wang, Sandra Mattu, Giulia Destefanis, Sara Ladu, Salvatore Delogu, Julia Armbruster, Lingling Fan, Susie A. Lee, Lijie Jiang, Frank Dombrowski, Matthias Evert, Xin Chen, Diego F. Calvisi

Hepatology. Author manuscript; available in PMC 2013 Mar 1.

Published in final edited form as: Hepatology. 2012 Mar; 55(3): 833–845. Published online 2011 Dec 19. doi: 10.1002/hep.24736

PMCID:: PMC3269553

Abstract Article PDF–2.4M

Select item 317805914.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 313868915.

Endogenous oncogenic Nras mutation initiates hematopoietic malignancies in a dose- and cell type-dependent manner

Jinyong Wang, Yangang Liu, Zeyang Li, Zhongde Wang, Li Xuan Tan, Myung-Jeom Ryu, Benjamin Meline, Juan Du, Ken H. Young, Erik Ranheim, Qiang Chang, Jing Zhang

Blood. 2011 Jul 14; 118(2): 368–379. Prepublished online 2011 May 17. doi: 10.1182/blood-2010-12-326058

PMCID:: PMC3138689

Abstract Article

Select item 292409816.

MicroRNA-214 Promotes Myogenic Differentiation by Facilitating Exit from Mitosis via Down-regulation of Proto-oncogene N-ras

Jun Liu, Xiao-ju Luo, An-wen Xiong, Zeng-di Zhang, Shen Yue, Ming-sheng Zhu, Steven Y. Cheng

J Biol Chem. 2010 Aug 20; 285(34): 26599–26607. Published online 2010 Jun 9. doi: 10.1074/jbc.M110.115824

PMCID:: PMC2924098

Abstract Article PDF–2.6M

Select item 265571917.

Regulator of G-Protein Signaling 14 (RGS14) Is a Selective H-Ras Effector

Francis S. Willard, Melinda D. Willard, Adam J. Kimple, Meera Soundararajan, Emily A. Oestreich, Xiaoyan Li, Nathaniel A. Sowa, Randall J. Kimple, Declan A. Doyle, Channing J. Der, Mark J. Zylka, William D. Snider, David P. Siderovski

PLoS One. 2009; 4(3): e4884. Published online 2009 Mar 25. doi: 10.1371/journal.pone.0004884

PMCID:: PMC2655719

Abstract Article PDF–1.6M

Select item 263507418.

RAS oncogene suppression induces apoptosis followed by more differentiated and less myelosuppressive disease upon relapse of acute myeloid leukemia

Won-Il Kim, Ilze Matise, Miechaleen D. Diers, David A. Largaespada

Blood. 2009 Jan 29; 113(5): 1086–1096. Prepublished online 2008 Oct 24. doi: 10.1182/blood-2008-01-132316

PMCID:: PMC2635074

Abstract Article

Select item 257560619.

Cia5d regulates a new fibroblast-like synoviocyte invasion-associated gene expression signature

Teresina Laragione, Max Brenner, Wentian Li, Pércio S Gulko

Arthritis Res Ther. 2008; 10(4): R92. Published online 2008 Aug 15. doi: 10.1186/ar2476

PMCID:: PMC2575606

Abstract Article PDF–676K

Select item 185278520.

Selective role for RGS12 as a Ras/Raf/MEK scaffold in nerve growth factor-mediated differentiation

Melinda D Willard, Francis S Willard, Xiaoyan Li, Steven D Cappell, William D Snider, David P Siderovski

EMBO J. 2007 Apr 18; 26(8): 2029–2040. Published online 2007 Mar 22. doi: 10.1038/sj.emboj.7601659

PMCID:: PMC1852785

Abstract Article PDF–392K

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