PMC Links for GEO Profiles (Select 3212795) - PMC

Manuel Johanns, Pascale Lemoine, Virginie Janssens, Giuseppina Grieco, Soren K. Moestrup, Rikke Nielsen, Erik I. Christensen, Pierre J. Courtoy, Hervé Emonard, Etienne Marbaix, Patrick Henriet

Sci Rep. 2017; 7: 4328. Published online 2017 Jun 28. doi: 10.1038/s41598-017-04648-y

PMCID:: PMC5489529

Abstract Article PDF–1.5M

Select item 48524994.

Common arterial trunk and ventricular non-compaction in Lrp2 knockout mice indicate a crucial role of LRP2 in cardiac development

Maria E. Baardman, Mathijs V. Zwier, Lambertus J. Wisse, Adriana C. Gittenberger-de Groot, Wilhelmina S. Kerstjens-Frederikse, Robert M. W. Hofstra, Angelika Jurdzinski, Beerend P. Hierck, Monique R. M. Jongbloed, Rolf M. F. Berger, Torsten Plösch, Marco C. DeRuiter

Dis Model Mech. 2016 Apr 1; 9(4): 413–425. doi: 10.1242/dmm.022053

PMCID:: PMC4852499

Abstract Article

Select item 47141935.

Low-density Lipoprotein Receptor-related Proteins in a Novel Mechanism of Axon Guidance and Peripheral Nerve Regeneration

Lila M. Landowski, Macarena Pavez, Lachlan S. Brown, Robert Gasperini, Bruce V. Taylor, Adrian K. West, Lisa Foa

J Biol Chem. 2016 Jan 15; 291(3): 1092–1102. Published online 2015 Nov 23. doi: 10.1074/jbc.M115.668996

PMCID:: PMC4714193

Abstract Article PDF–1.7M

Select item 46175406.

Global genetic analysis in mice unveils central role for cilia in congenital heart disease

You Li, Nikolai T. Klena, George C Gabriel, Xiaoqin Liu, Andrew J. Kim, Kristi Lemke, Yu Chen, Bishwanath Chatterjee, William Devine, Rama Rao Damerla, Chien-fu Chang, Hisato Yagi, Jovenal T. San Agustin, Mohamed Thahir, Shane Anderton, Caroline Lawhead, Anita Vescovi, Herbert Pratt, Judy Morgan, Leslie Haynes, Cynthia L. Smith, Janan T. Eppig, Laura Reinholdt, Richard Francis, Linda Leatherbury, Madhavi K. Ganapathiraju, Kimimasa Tobita, Gregory J. Pazour, Cecilia W. Lo

Nature. Author manuscript; available in PMC 2015 Nov 28.

Published in final edited form as: Nature. 2015 May 28; 521(7553): 520–524. Published online 2015 Mar 25. doi: 10.1038/nature14269

PMCID:: PMC4617540

Abstract Article PDF–518K

Select item 45050487.

Megalin/Cubulin-Lysosome-mediated Albumin Reabsorption Is Involved in the Tubular Cell Activation of NLRP3 Inflammasome and Tubulointerstitial Inflammation

Dan Liu, Yi Wen, Tao-Tao Tang, Lin-Li Lv, Ri-Ning Tang, Hong Liu, Kun-Ling Ma, Steve D. Crowley, Bi-Cheng Liu

J Biol Chem. 2015 Jul 17; 290(29): 18018–18028. Published online 2015 May 29. doi: 10.1074/jbc.M115.662064

PMCID:: PMC4505048

Abstract Article PDF–5.0M

Select item 39578058.

Epithelial Trafficking of Sonic Hedgehog by Megalin

Carlos R. Morales, Jibin Zeng, Mohamed El Alfy, Jeremy L. Barth, Mastan Rao Chintalapudi, Robert A. McCarthy, John P. Incardona, W. Scott Argraves

J Histochem Cytochem. 2006 Oct; 54(10): 1115–1127. doi: 10.1369/jhc.5A6899.2006

PMCID:: PMC3957805

Abstract Article PDF–1.2M

Select item 39305179.

Arf4 Is Required for Mammalian Development but Dispensable for Ciliary Assembly

John A. Follit, Jovenal T. San Agustin, Julie A. Jonassen, Tingting Huang, Jaime A. Rivera-Perez, Kimberly D. Tremblay, Gregory J. Pazour

PLoS Genet. 2014 Feb; 10(2): e1004170. Published online 2014 Feb 20. doi: 10.1371/journal.pgen.1004170

PMCID:: PMC3930517

Abstract Article PDF–7.3M

Select item 377350510.

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

Simona Principe, E. Ellen Jones, Yunee Kim, Ankit Sinha, Julius O. Nyalwidhe, Jasmin Brooks, O. John Semmes, Dean A. Troyer, Raymond S. Lance, Thomas Kislinger, Richard R. Drake

Proteomics. Author manuscript; available in PMC 2014 May 1.

Published in final edited form as: Proteomics. 2013 May; 13(0): 1667–1671. Published online 2013 Apr 23. doi: 10.1002/pmic.201200561

PMCID:: PMC3773505

Abstract Article PDF–630K

Select item 370497911.

ARH directs megalin to the endocytic recycling compartment to regulate its proteolysis and gene expression

Mehul Shah, Oscar Y. Baterina, Jr., Vanessa Taupin, Marilyn G. Farquhar

J Cell Biol. 2013 Jul 8; 202(1): 113–127. doi: 10.1083/jcb.201211110

PMCID:: PMC3704979

Abstract Article PDF–2.8M

Select item 358195412.

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins

Rajesh Ghai, Andrea Bugarcic, Huadong Liu, Suzanne J. Norwood, Sune Skeldal, Elizabeth J. Coulson, Shawn Shun-Cheng Li, Rohan D. Teasdale, Brett M. Collins

Proc Natl Acad Sci U S A. 2013 Feb 19; 110(8): E643–E652. Published online 2013 Feb 4. doi: 10.1073/pnas.1216229110

PMCID:: PMC3581954

Abstract Article PDF–2.3M

Select item 356769213.

Gentamicin Binds to the Megalin Receptor as a Competitive Inhibitor Using the Common Ligand Binding Motif of Complement Type Repeats: INSIGHT FROM THE NMR STRUCTURE OF THE 10TH COMPLEMENT TYPE REPEAT DOMAIN ALONE AND IN COMPLEX WITH GENTAMICIN

Robert Dagil, Charlotte O'Shea, Anders Nykjær, Alexandre M. J. J. Bonvin, Birthe B. Kragelund

J Biol Chem. 2013 Feb 8; 288(6): 4424–4435. Published online 2012 Dec 27. doi: 10.1074/jbc.M112.434159

PMCID:: PMC3567692

Abstract Article PDF–2.1M

Select item 317805914.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 300992015.

Intrarenal Renin Angiotensin System Revisited: ROLE OF MEGALIN-DEPENDENT ENDOCYTOSIS ALONG THE PROXIMAL NEPHRON

Marcus Pohl, Henriette Kaminski, Hayo Castrop, Michael Bader, Nina Himmerkus, Markus Bleich, Sebastian Bachmann, Franziska Theilig

J Biol Chem. 2010 Dec 31; 285(53): 41935–41946. Published online 2010 Oct 21. doi: 10.1074/jbc.M110.150284

PMCID:: PMC3009920

Abstract Article PDF–2.7M

Select item 284899016.

Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses

Siân Jones, Xiaosong Zhang, D. Williams Parsons, Jimmy Cheng-Ho Lin, Rebecca J. Leary, Philipp Angenendt, Parminder Mankoo, Hannah Carter, Hirohiko Kamiyama, Antonio Jimeno, Seung-Mo Hong, Baojin Fu, Ming-Tseh Lin, Eric S. Calhoun, Mihoko Kamiyama, Kimberly Walter, Tatiana Nikolskaya, Yuri Nikolsky, James Hartigan, Douglas R. Smith, Manuel Hidalgo, Steven D. Leach, Alison P. Klein, Elizabeth M. Jaffee, Michael Goggins, Anirban Maitra, Christine Iacobuzio-Donahue, James R. Eshleman, Scott E. Kern, Ralph H. Hruban, Rachel Karchin, Nickolas Papadopoulos, Giovanni Parmigiani, Bert Vogelstein, Victor E. Velculescu, Kenneth W. Kinzler

Science. Author manuscript; available in PMC 2010 Apr 4.

Published in final edited form as: Science. 2008 Sep 26; 321(5897): 1801–1806. Published online 2008 Sep 4. doi: 10.1126/science.1164368

PMCID:: PMC2848990

Abstract Article PDF–971K

Select item 263705017.

Large-Scale Proteomics and Phosphoproteomics of Urinary Exosomes

Patricia A. Gonzales, Trairak Pisitkun, Jason D. Hoffert, Dmitry Tchapyjnikov, Robert A. Star, Robert Kleta, Nam Sun Wang, Mark A. Knepper

J Am Soc Nephrol. 2009 Feb; 20(2): 363–379. doi: 10.1681/ASN.2008040406

PMCID:: PMC2637050

Abstract Article

Select item 204026318.

Megalin binds and internalizes angiotensin-(1-7)

Romer Gonzalez-Villalobos, R. Bryan Klassen, Patricia L. Allen, Kelly Johanson, Chasity B. Baker, Hiroyuki Kobori, L. G. Navar, Timothy G. Hammond

Am J Physiol Renal Physiol. Author manuscript; available in PMC 2007 Oct 23.

Published in final edited form as: Am J Physiol Renal Physiol. 2006 May; 290(5): F1270–F1275. Published online 2005 Dec 27. doi: 10.1152/ajprenal.00164.2005

PMCID:: PMC2040263

Abstract Article PDF–374K

Select item 122099619.

Cytosolic adaptor protein Dab2 is an intracellular ligand of endocytic receptor gp600/megalin.

A V Oleinikov, J Zhao, S P Makker

Biochem J. 2000 May 1; 347(Pt 3): 613–621.

PMCID:: PMC1220996

Summary PDF–205K

Select item 38773120.

Normal Development and Fertility of Knockout Mice Lacking the Tumor Suppressor Gene LRP1b Suggest Functional Compensation by LRP1

Peter Marschang, Jochen Brich, Edwin J. Weeber, J. David Sweatt, John M. Shelton, James A. Richardson, Robert E. Hammer, Joachim Herz

Mol Cell Biol. 2004 May; 24(9): 3782–3793. doi: 10.1128/MCB.24.9.3782-3793.2004

PMCID:: PMC387731

Abstract Article PDF–543K

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