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Select item 77857071.

Maf1 Ameliorates Sepsis-Associated Encephalopathy by Suppressing the NF-kB/NLRP3 Inflammasome Signaling Pathway

Shenglong Chen, Chaogang Tang, Hongguang Ding, Zhonghua Wang, Xinqiang Liu, Yunfei Chai, Wenqiang Jiang, Yongli Han, Hongke Zeng

Front Immunol. 2020; 11: 594071. Published online 2020 Dec 23. doi: 10.3389/fimmu.2020.594071

PMCID:: PMC7785707

Abstract Article PDF–3.8M

Select item 67933542.

p21 Ras and Phosphatidylinositol-3 Kinase Are Required for Survival of Wild-Type and NF1 Mutant Sensory Neurons

Laura J. Klesse, Luis F. Parada

J Neurosci. 1998 Dec 15; 18(24): 10420–10428. doi: 10.1523/JNEUROSCI.18-24-10420.1998

PMCID:: PMC6793354

Abstract Article PDF–677K

Select item 67830813.

α-Synuclein Shares Physical and Functional Homology with 14-3-3 Proteins

Natalie Ostrerova, Leonard Petrucelli, Matthew Farrer, Nitinkumar Mehta, Peter Choi, John Hardy, Benjamin Wolozin

J Neurosci. 1999 Jul 15; 19(14): 5782–5791. doi: 10.1523/JNEUROSCI.19-14-05782.1999

PMCID:: PMC6783081

Abstract Article PDF–852K

Select item 67622764.

Stimulation of Endothelin B Receptors in Astrocytes Induces cAMP Response Element-Binding Protein Phosphorylation and c-fos Expression Via Multiple Mitogen-Activated Protein Kinase Signaling Pathways

Sergio Schinelli, Patrizia Zanassi, Mayra Paolillo, Hang Wang, Antonio Feliciello, Vittorio Gallo

J Neurosci. 2001 Nov 15; 21(22): 8842–8853. doi: 10.1523/JNEUROSCI.21-22-08842.2001

PMCID:: PMC6762276

Abstract Article PDF–1.3M

Select item 63127265.

Protein Arginine Methyltransferase 5 Regulates ERK1/2 Signal Transduction Amplitude and Cell Fate Through CRAF

Pedro Andreu-Pérez, Rosaura Esteve-Puig, Carlos de Torre-Minguela, Marta López-Fauqued, Joan Josep Bech-Serra, Stephan Tenbaum, Elena R. García-Trevijano, Francesc Canals, Glenn Merlino, Matías A. Ávila, Juan A. Recio

Sci Signal. Author manuscript; available in PMC 2019 Jan 1.

Published in final edited form as: Sci Signal. 2011 Sep 13; 4(190): ra58. doi: 10.1126/scisignal.2001936

PMCID:: PMC6312726

Abstract Article PDF–1.8M

Select item 61011366.

The E3 ubiquitin ligase HERC1 controls the ERK signaling pathway targeting C-RAF for degradation

Taiane Schneider, Arturo Martinez-Martinez, Monica Cubillos-Rojas, Ramon Bartrons, Francesc Ventura, Jose Luis Rosa

Oncotarget. 2018 Jul 31; 9(59): 31531–31548. Published online 2018 Jul 31. doi: 10.18632/oncotarget.25847

PMCID:: PMC6101136

Abstract Article PDF–6.3M

Select item 40422187.

Multikinase inhibitor sorafenib prevents pressure overload-induced left ventricular hypertrophy in rats by blocking the c-Raf/ERK1/2 signaling pathway

Arezoo Daryadel, Anna Bogdanova, Max Gassmann, Xavier Mueller, Gregor Zünd, Burkhardt Seifert, Christine Lehalle, Nelly Frossard, Reza Tavakoli

J Cardiothorac Surg. 2014; 9: 81. Published online 2014 May 9. doi: 10.1186/1749-8090-9-81

PMCID:: PMC4042218

Abstract Article PDF–2.0M

Select item 39519998.

Nilotinib and MEK inhibitors induce synthetic lethality through paradoxical activation of RAF in drug-resistant chronic myeloid leukemia

Leisl M. Packer, Sareena Rana, Robert Hayward, Thomas O'Hare, Christopher A. Eide, Ana Rebocho, Sonja Heidorn, Matthew S. Zabriskie, Ion Niculescu-Duvaz, Brian J. Druker, Caroline Springer, Richard Marais

Cancer Cell. Author manuscript; available in PMC 2014 Mar 13.

Published in final edited form as: Cancer Cell. 2011 Dec 13; 20(6): 715–727. doi: 10.1016/j.ccr.2011.11.004

PMCID:: PMC3951999

Abstract Article PDF–977K

Select item 37390159.

X-linked Inhibitor of Apoptosis Protein negatively regulates neuronal differentiation through interaction with cRAF and Trk

Rut Fadó, Rana S. Moubarak, Alfredo J. Miñano-Molina, Bruna Barneda-Zahonero, Jorge Valero, Carlos A. Saura, Julio Moran, Joan X. Comella, José Rodríguez-Álvarez

Sci Rep. 2013; 3: 2397. Published online 2013 Aug 9. doi: 10.1038/srep02397

PMCID:: PMC3739015

Abstract Article PDF–1.7M

Select item 371281810.

Raf-1 Kinase Regulates Smooth Muscle Contraction in the Rat Mesenteric Arteries

Kunju Sathishkumar, Uma Yallampalli, Rebekah Elkins, Chandra Yallampalli

J Vasc Res. 2010 Aug; 47(5): 384–398. Published online 2010 Jan 27. doi: 10.1159/000277726

PMCID:: PMC3712818

Abstract Article PDF–782K

Select item 364884911.

Role of the Protein Kinase C-ε–Raf-1–MEK-1/2–p44/42 MAPK Signaling Cascade in the Activation of Signal Transducers and Activators of Transcription 1 and 3 and Induction of Cyclooxygenase-2 After Ischemic Preconditioning

Yu-Ting Xuan, Yiru Guo, Yanqing Zhu, Ou-Li Wang, Gregg Rokosh, Robert O. Messing, Roberto Bolli

Circulation. Author manuscript; available in PMC 2013 May 9.

Published in final edited form as: Circulation. 2005 Sep 27; 112(13): 1971–1978. Published online 2005 Sep 19. doi: 10.1161/CIRCULATIONAHA.105.561522

PMCID:: PMC3648849

Abstract Article PDF–4.9M

Select item 363162912.

Phosphodiesterase-8A binds to and regulates Raf-1 kinase

Kim M. Brown, Jon P. Day, Elaine Huston, Bastian Zimmermann, Kornelia Hampel, Frank Christian, David Romano, Selim Terhzaz, Louisa C. Y. Lee, Miranda J. Willis, David B. Morton, Joseph A. Beavo, Masami Shimizu-Albergine, Shireen A. Davies, Walter Kolch, Miles D. Houslay, George S. Baillie

Proc Natl Acad Sci U S A. 2013 Apr 16; 110(16): E1533–E1542. Published online 2013 Mar 18. doi: 10.1073/pnas.1303004110

PMCID:: PMC3631629

Abstract Article PDF–1.7M

Select item 358211613.

Endothelial ERK signaling controls lymphatic fate specification

Yong Deng, Deepak Atri, Anne Eichmann, Michael Simons

J Clin Invest. 2013 Mar 1; 123(3): 1202–1215. Published online 2013 Feb 8. doi: 10.1172/JCI63034

PMCID:: PMC3582116

Abstract Article PDF–9.8M

Select item 345753414.

Increased BRAF Heterodimerization Is the Common Pathogenic Mechanism for Noonan Syndrome-Associated RAF1 Mutants

Xue Wu, Jiani Yin, Jeremy Simpson, Kyoung-Han Kim, Shengqing Gu, Jenny H. Hong, Peter Bayliss, Peter H. Backx, Benjamin G. Neel, Toshiyuki Araki

Mol Cell Biol. 2012 Oct; 32(19): 3872–3890. doi: 10.1128/MCB.00751-12

PMCID:: PMC3457534

Abstract Article PDF–6.1M

Select item 339061715.

Raf Kinase Inhibitor Protein (RKIP) Dimer Formation Controls Its Target Switch from Raf1 to G Protein-coupled Receptor Kinase (GRK) 2

Katharina Deiss, Caroline Kisker, Martin J. Lohse, Kristina Lorenz

J Biol Chem. 2012 Jul 6; 287(28): 23407–23417. Published online 2012 May 17. doi: 10.1074/jbc.M112.363812

PMCID:: PMC3390617

Abstract Article PDF–1.0M

Select item 336541316.

Distinct requirement for an intact dimer interface in wild-type, V600E and kinase-dead B-Raf signalling

Michael Röring, Ricarda Herr, Gina J Fiala, Katharina Heilmann, Sandra Braun, Anja E Eisenhardt, Sebastian Halbach, David Capper, Andreas von Deimling, Wolfgang W Schamel, Darren N Saunders, Tilman Brummer

EMBO J. 2012 May 30; 31(11): 2629–2647. Published online 2012 Apr 17. doi: 10.1038/emboj.2012.100

PMCID:: PMC3365413

Abstract Article PDF–3.1M

Select item 320583317.

Pancreatic β-cell Raf-1 is required for glucose tolerance, insulin secretion, and insulin 2 transcription

Emilyn U. Alejandro, Gareth E. Lim, Arya E. Mehran, Xiaoke Hu, Farnaz Taghizadeh, Dmytro Pelipeychenko, Manuela Baccarini, James D. Johnson

FASEB J. 2011 Nov; 25(11): 3884–3895. doi: 10.1096/fj.10-180349

PMCID:: PMC3205833

Abstract Article

Select item 317805918.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 310359519.

Cyclosporine attenuates cardiomyocyte hypertrophy induced by RAF1 mutants in Noonan and LEOPARD syndromes

Perundurai S Dhandapany, Frank Fabris, Rahul Tonk, Ardo Illaste, Ioannis Karakikes, Mehran Sorourian, Jipo Sheng, Roger J. Hajjar, Marco Tartaglia, Eric A. Sobie, Djamel Lebeche, Bruce D. Gelb

J Mol Cell Cardiol. Author manuscript; available in PMC 2012 Jul 1.

Published in final edited form as: J Mol Cell Cardiol. 2011 Jul; 51(1): 4–15. Published online 2011 Apr 8. doi: 10.1016/j.yjmcc.2011.03.001