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Select item 94519211.

Methylation-mediated silencing of PTPRD induces pulmonary hypertension by promoting pulmonary arterial smooth muscle cell migration via the PDGFRB/PLCγ1 axis

Junhua Xu, Yanfeng Zhong, Haoyang Yin, John Linneman, Yixuan Luo, Sijian Xia, Qinyi Xia, Lei Yang, Xingtao Huang, Kang Kang, Jun Wang, Yanqin Niu, Li Li, Deming Gou

J Hypertens. 2022 Sep; 40(9): 1795–1807. Published online 2022 Jul 25. doi: 10.1097/HJH.0000000000003220

PMCID:: PMC9451921

Abstract Article PDF–3.6M

Select item 80767962.

Personal Neoantigens From Patients With NSCLC Induce Efficient Antitumor Responses

Wei Zhang, Qi Yin, Haidong Huang, Jingjing Lu, Hao Qin, Si Chen, Wenjun Zhang, Xiaoping Su, Weihong Sun, Yuchao Dong, Qiang Li

Front Oncol. 2021; 11: 628456. Published online 2021 Apr 13. doi: 10.3389/fonc.2021.628456

PMCID:: PMC8076796

Abstract Article PDF–1.3M

Select item 78084623.

Model establishment of prognostic-related immune genes in laryngeal squamous cell carcinoma

Ming Sun, Sihan Chen, Min Fu

Medicine (Baltimore) 2021 Jan 15; 100(2): e24263. Published online 2021 Jan 15. doi: 10.1097/MD.0000000000024263

PMCID:: PMC7808462

Abstract Article PDF–1.3M

Select item 76104194.

PLCγ1 suppression promotes the adaptation of KRAS-mutant lung adenocarcinomas to hypoxia

Maria Saliakoura, Matteo Rossi Sebastiano, Chiara Pozzato, Florian H. Heidel, Tina M. Schnöder, Spasenija Savic Prince, Lukas Bubendorf, Paolo Pinton, Ralph Schmid, Johanna Baumgartner, Stefan Freigang, Sabina A. Berezowska, Alessandro Rimessi, Georgia Konstantinidou

Nat Cell Biol. Author manuscript; available in PMC 2021 Apr 19.

Published in final edited form as: Nat Cell Biol. 2020 Nov 1; 22(11): 1382–1395. Published online 2020 Oct 19. doi: 10.1038/s41556-020-00592-8

PMCID:: PMC7610419

Abstract Article PDF–8.7M

Select item 67407615.

Phospholipase Cγ in Distinct Regions of the Ventral Tegmental Area Differentially Modulates Mood-Related Behaviors

Carlos A. Bolaños, Linda I. Perrotti, Scott Edwards, Amelia J. Eisch, Michel Barrot, Valerie G. Olson, David S. Russell, Rachael L. Neve, Eric J. Nestler

J Neurosci. 2003 Aug 20; 23(20): 7569–7576. doi: 10.1523/JNEUROSCI.23-20-07569.2003

PMCID:: PMC6740761

Abstract Article PDF–419K

Select item 66222376.

TRPC5 Channel Is the Mediator of Neurotrophin-3 in Regulating Dendritic Growth via CaMKIIα in Rat Hippocampal Neurons

Zhuohao He, Caixia Jia, Shengjie Feng, Kechun Zhou, Yilin Tai, Xue Bai, Yizheng Wang

J Neurosci. 2012 Jul 4; 32(27): 9383–9395. doi: 10.1523/JNEUROSCI.6363-11.2012

PMCID:: PMC6622237

Abstract Article PDF–3.7M

Select item 55862857.

Phospholipase Cγ1 Mediates Intima Formation Through Akt‐Notch1 Signaling Independent of the Phospholipase Activity

Dongyang Jiang, Jianhui Zhuang, Wenhui Peng, Yuyan Lu, Hao Liu, Qian Zhao, Chen Chi, Xiankai Li, Guofu Zhu, Xiangbin Xu, Chen Yan, Yawei Xu, Junbo Ge, Jinjiang Pang

J Am Heart Assoc. 2017 Jul; 6(7): e005537. Published online 2017 Jul 11. doi: 10.1161/JAHA.117.005537

PMCID:: PMC5586285

Abstract Article PDF–2.7M

Select item 54070178.

c-Jun enhances intestinal epithelial restitution after wounding by increasing phospholipase C-γ1 transcription

Peng-Yuan Wang, Shelley R. Wang, Lan Xiao, Jie Chen, Jian-Ying Wang, Jaladanki N. Rao

Am J Physiol Cell Physiol. 2017 Apr 1; 312(4): C367–C375. Published online 2017 Jan 18. doi: 10.1152/ajpcell.00330.2016

PMCID:: PMC5407017

Abstract Article

Select item 49916769.

Periodic mechanical stress induces the extracellular matrix expression and migration of rat nucleus pulposus cells by upregulating the expression of intergrin α1 and phosphorylation of downstream phospholipase Cγ1

Gongming Gao, Jin He, Luming Nong, Hua Xie, Yongjing Huang, Nanwei Xu, Dong Zhou

Mol Med Rep. 2016 Sep; 14(3): 2457–2464. Published online 2016 Jul 27. doi: 10.3892/mmr.2016.5549

PMCID:: PMC4991676

Abstract Article PDF–1.0M

Select item 495597710.

Phospholipase C gamma mediates endogenous brain-derived neurotrophic factor-regulated calcitonin gene-related peptide expression in colitis-induced visceral pain

Fiza Hashmi, Miao Liu, Shanwei Shen, Li-Ya Qiao

Mol Pain. 2016; 12: 1744806916657088. Published online 2016 Jun 15. doi: 10.1177/1744806916657088

PMCID:: PMC4955977

Abstract Article PDF–1.7M

Select item 483819011.

Two FGFR kinase molecules act in concert to recruit and transphosphorylate PLCγ

Zhifeng Huang, William M. Marsiglia, Upal BasuRoy, Nader Rahimi, Dariush Ilghari, Huiyan Wang, Huaibin Chen, Weiming Gai, Steven Blais, Thomas A. Neubert, Alka Mansukhani, Nathaniel J. Traaseth, Xiaokun Li, Moosa Mohammadi

Mol Cell. Author manuscript; available in PMC 2017 Jan 7.

Published in final edited form as: Mol Cell. 2016 Jan 7; 61(1): 98–110. Published online 2015 Dec 10. doi: 10.1016/j.molcel.2015.11.010

Correction in:: volume 61 on page 324

PMCID:: PMC4838190

Abstract Article PDF–1.1M

Select item 476408012.

Structural basis underlying a novel mechanism for control of receptor tyrosine kinase signal selectivity

Jae Hyun Bae, Erin Denise Lew, Satoru Yuzawa, Francisco Tome, Irit Lax, Joseph Schlessinger

Cell. Author manuscript; available in PMC 2016 Feb 23.

Published in final edited form as: Cell. 2009 Aug 7; 138(3): 514–524. doi: 10.1016/j.cell.2009.05.028

PMCID:: PMC4764080

Abstract Article PDF–3.0M

Select item 458387813.

Reduced expression of E-cadherin and p120-catenin and elevated expression of PLC-γ1 and PIKE are associated with aggressiveness of oral squamous cell carcinoma

Yi Jiang, Liyan Liao, Chandrama Shrestha, Shangli Ji, Ying Chen, Jian Peng, Larry Wang, Eryuan Liao, Zhongjian Xie

Int J Clin Exp Pathol. 2015; 8(8): 9042–9051. Published online 2015 Aug 1.

PMCID:: PMC4583878

Abstract Article PDF–1.0M

Select item 446886014.

Microtubule-associated protein 6 mediates neuronal connectivity through Semaphorin 3E-dependent signalling for axonal growth

Jean-Christophe Deloulme, Sylvie Gory-Fauré, Franck Mauconduit, Sophie Chauvet, Julie Jonckheere, Benoit Boulan, Erik Mire, Jing Xue, Marion Jany, Caroline Maucler, Agathe A. Deparis, Olivier Montigon, Alexia Daoust, Emmanuel L. Barbier, Christophe Bosc, Nicole Deglon, Jacques Brocard, Eric Denarier, Isabelle Le Brun, Karin Pernet-Gallay, Isabelle Vilgrain, Phillip J. Robinson, Hana Lahrech, Fanny Mann, Annie Andrieux

Nat Commun. 2015; 6: 7246. Published online 2015 Jun 3. doi: 10.1038/ncomms8246