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Select item 103304431.

Interspecies Variation Affects IAPP Membrane Binding

Henry M. Sanders, Farzaneh Chalyavi, Caitlyn R. Fields, Marius M. Kostelic, Ming-Hao Li, Daniel P. Raleigh, Martin T. Zanni, Michael T. Marty

J Am Soc Mass Spectrom. Author manuscript; available in PMC 2024 Jun 7.

Published in final edited form as: J Am Soc Mass Spectrom. 2023 Jun 7; 34(6): 986–990. Published online 2023 Apr 26. doi: 10.1021/jasms.3c00005

PMCID:: PMC10330443

Abstract Article PDF–806K

Select item 73167122.

Amylin and beta amyloid proteins interact to form amorphous heterocomplexes with enhanced toxicity in neuronal cells

Prashant Bharadwaj, Tanya Solomon, Bikash R. Sahoo, Katarzyna Ignasiak, Scott Gaskin, Joanne Rowles, Giuseppe Verdile, Mark J. Howard, Charles S. Bond, Ayyalusamy Ramamoorthy, Ralph N. Martins, Philip Newsholme

Sci Rep. 2020; 10: 10356. Published online 2020 Jun 25. doi: 10.1038/s41598-020-66602-9

PMCID:: PMC7316712

Abstract Article PDF–2.0M

Select item 72804743.

Involvement of amylin B-H₂S-connexin 43 signaling pathway in vascular dysfunction and enhanced ischemia–reperfusion-induced myocardial injury in diabetic rats

Xiaoyong Liu, Rui Yang, Wenwei Bai, Xiang Xu, Feng Bi, Yingzheng Hao, Qishi Yang, Hu Li

Biosci Rep. 2020 Jun 26; 40(6): BSR20194154. Published online 2020 Jun 8. doi: 10.1042/BSR20194154

PMCID:: PMC7280474

Abstract Article PDF–1.4M

Select item 58452064.

Lipid accelerating the fibril of islet amyloid polypeptide aggravated the pancreatic islet injury in vitro and in vivo

Xiao-Dan Mo, Li-Ping Gao, Qing-Jun Wang, Jie Yin, Yu-Hong Jing

Lipids Health Dis. 2018; 17: 42. Published online 2018 Mar 9. doi: 10.1186/s12944-018-0694-8

PMCID:: PMC5845206

Abstract Article PDF–2.0M

Select item 55996865.

Novel insight into streptozotocin-induced diabetic rats from the protein misfolding perspective

Edgar Leyva-García, Reyna Lara-Martínez, Liborio Morán-Zanabria, Cristina Revilla-Monsalve, Luis Felipe Jiménez-García, Norma Oviedo, Chiharu Murata, Eulalia Garrido-Magaña, Nelly F. Altamirano-Bustamante, Myriam M. Altamirano-Bustamante

Sci Rep. 2017; 7: 11552. Published online 2017 Sep 14. doi: 10.1038/s41598-017-11776-y

PMCID:: PMC5599686

Abstract Article PDF–3.3M

Select item 50768346.

C4b-binding Protein Protects β-Cells from Islet Amyloid Polypeptide-induced Cytotoxicity

Jonatan Sjölander, Elin Byman, Klaudia Kulak, Sara C. Nilsson, Enming Zhang, Ulrika Krus, Gunilla T. Westermark, Petter Storm, Ben C. King, Erik Renström, Anna M. Blom

J Biol Chem. 2016 Oct 7; 291(41): 21644–21655. Published online 2016 Aug 26. doi: 10.1074/jbc.M116.731141

PMCID:: PMC5076834

Abstract Article PDF–2.5M

Select item 48683687.

Endogenous VMH amylin signaling is required for full leptin signaling and protection from diet-induced obesity

Ambrose A. Dunn-Meynell, Christelle Le Foll, Miranda D. Johnson, Thomas A. Lutz, Matthew R. Hayes, Barry E. Levin

Am J Physiol Regul Integr Comp Physiol. 2016 Feb 15; 310(4): R355–R365. Published online 2015 Dec 16. doi: 10.1152/ajpregu.00462.2015

PMCID:: PMC4868368

Abstract Article

Select item 47396988.

Identification of Human Islet Amyloid Polypeptide as a BACE2 Substrate

Ingrid C. Rulifson, Ping Cao, Li Miao, David Kopecky, Linda Huang, Ryan D. White, Kim Samayoa, Jonitha Gardner, Xiaosu Wu, Kui Chen, Trace Tsuruda, Oliver Homann, Helene Baribault, Harvey Yamane, Tim Carlson, Jed Wiltzius, Yang Li

PLoS One. 2016; 11(2): e0147254. Published online 2016 Feb 3. doi: 10.1371/journal.pone.0147254

PMCID:: PMC4739698

Abstract Article PDF–4.3M

Select item 45193429.

Secondary Structure of Rat and Human Amylin across Force Fields

Kyle Quynn Hoffmann, Michael McGovern, Chi-cheng Chiu, Juan J. de Pablo

PLoS One. 2015; 10(7): e0134091. Published online 2015 Jul 29. doi: 10.1371/journal.pone.0134091

PMCID:: PMC4519342

Abstract Article PDF–7.9M

Select item 431616410.

Inhibition of IAPP aggregation by insulin depends on the insulin oligomeric state regulated by zinc ion concentration

Praveen Nedumpully-Govindan, Feng Ding

Sci Rep. 2015; 5: 8240. Published online 2015 Feb 4. doi: 10.1038/srep08240

PMCID:: PMC4316164

Abstract Article PDF–913K

Select item 416302211.

Three-Dimensional Structure and Orientation of Rat Islet Amyloid Polypeptide Protein in a Membrane Environment by Solution NMR Spectroscopy

Ravi Prakash Reddy Nanga, Jeffrey R. Brender, Jiadi Xu, Kevin Hartman, Vivekanandan Subramanian, Ayyalusamy Ramamoorthy

J Am Chem Soc. Author manuscript; available in PMC 2014 Sep 13.

Published in final edited form as: J Am Chem Soc. 2009 Jun 17; 131(23): 8252–8261. doi: 10.1021/ja9010095

PMCID:: PMC4163022

Abstract Article PDF–1.2M

Select item 415568912.

Phosphorylation and Degradation of Tomosyn-2 De-represses Insulin Secretion

Sushant Bhatnagar, Mufaddal S. Soni, Lindsay S. Wrighton, Alexander S. Hebert, Amber S. Zhou, Pradyut K. Paul, Trillian Gregg, Mary E. Rabaglia, Mark P. Keller, Joshua J. Coon, Alan D. Attie

J Biol Chem. 2014 Sep 5; 289(36): 25276–25286. Published online 2014 Jul 7. doi: 10.1074/jbc.M114.575985

PMCID:: PMC4155689

Abstract Article PDF–1.1M

Select item 384580113.

Blockade of Islet Amyloid Polypeptide Fibrillation and Cytotoxicity by the Secretory Chaperones 7B2 and proSAAS

Juan R. Peinado, Furqan Sami, Nina Rajpurohit, Iris Lindberg

FEBS Lett. Author manuscript; available in PMC 2014 Nov 1.

Published in final edited form as: FEBS Lett. 2013 Nov 1; 587(21): 10.1016/j.febslet.2013.09.006. Published online 2013 Sep 13. doi: 10.1016/j.febslet.2013.09.006