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Select item 107514471.

Receptor interacting protein kinase‐3 mediates both myopathy and cardiomyopathy in preclinical animal models of Duchenne muscular dystrophy

Maximilien Bencze, Baptiste Periou, Isabel Punzón, Inès Barthélémy, Valentina Taglietti, Cyrielle Hou, Louai Zaidan, Kaouthar Kefi, Stéphane Blot, Onnik Agbulut, Marianne Gervais, Geneviève Derumeaux, François‐Jérôme Authier, Laurent Tiret, Fréderic Relaix

J Cachexia Sarcopenia Muscle. 2023 Dec; 14(6): 2520–2531. Published online 2023 Nov 1. doi: 10.1002/jcsm.13265

PMCID:: PMC10751447

Abstract Article PDF–3.7M

Select item 95556452.

Inhibition of RIP1-RIP3-mediated necroptosis attenuates renal fibrosis via Wnt3α/β-catenin/GSK-3β signaling in unilateral ureteral obstruction

Shang Guo Piao, Jun Ding, Xue Jing Lin, Qi Yan Nan, Mei Ying Xuan, Yu Ji Jiang, Hai Lan Zheng, Ji Zhe Jin, Can Li

PLoS One. 2022; 17(10): e0274116. Published online 2022 Oct 12. doi: 10.1371/journal.pone.0274116

PMCID:: PMC9555645

Abstract Article PDF–4.9M

Select item 90231753.

RIP3 Contributes to Cardiac Hypertrophy by Influencing MLKL-Mediated Calcium Influx

Honghong Xue, Hongtao Shi, Fan Zhang, Hao Li, Chao Li, Qinghua Han

Oxid Med Cell Longev. 2022; 2022: 5490553. Published online 2022 Apr 14. doi: 10.1155/2022/5490553

PMCID:: PMC9023175

Abstract Article PDF–2.6M

Select item 88443554.

RIPK1-RIPK3 mediates myocardial fibrosis in type 2 diabetes mellitus by impairing autophagic flux of cardiac fibroblasts

Shigang Qiao, Lei Hong, Yongming Zhu, Jun Zha, An Wang, Jia Qiu, Wei Li, Chen Wang, Jianzhong An, Huiling Zhang

Cell Death Dis. 2022 Feb; 13(2): 147. Published online 2022 Feb 14. doi: 10.1038/s41419-022-04587-1

PMCID:: PMC8844355

Abstract Article PDF–4.9M

Select item 86101115.

RIP3 Inhibition ameliorates chronic constriction injury-induced neuropathic pain by suppressing JNK signaling

Na He, Yu-Juan Qu, Dan-Yang Li, Shou-Wei Yue

Aging (Albany NY) 2021 Nov 15; 13(21): 24417–24431. Published online 2021 Nov 12. doi: 10.18632/aging.203691

PMCID:: PMC8610111

Abstract Article PDF–1.4M

Select item 83471336.

Inhibition of Cardiac RIP3 Mitigates Early Reperfusion Injury and Calcium-Induced Mitochondrial Swelling without Altering Necroptotic Signalling

Csaba Horvath, Megan Young, Izabela Jarabicova, Lucia Kindernay, Kristina Ferenczyova, Tanya Ravingerova, Martin Lewis, M. Saadeh Suleiman, Adriana Adameova

Int J Mol Sci. 2021 Aug; 22(15): 7983. Published online 2021 Jul 26. doi: 10.3390/ijms22157983

PMCID:: PMC8347133

Abstract Article PDF–2.0M

Select item 82094857.

TNF-mediated alveolar macrophage necroptosis drives disease pathogenesis during respiratory syncytial virus infection

Leonardo Duarte Santos, Krist Helen Antunes, Stéfanie Primon Muraro, Gabriela Fabiano de Souza, Amanda Gonzalez da Silva, Jaqueline de Souza Felipe, Larissa Cardoso Zanetti, Rafael Sanguinetti Czepielewski, Karen Magnus, Marcelo Scotta, Rita Mattiello, Fabio Maito, Ana Paula Duarte de Souza, Ricardo Weinlich, Marco Aurélio Ramirez Vinolo, Bárbara Nery Porto

Eur Respir J. 2021 Jun; 57(6): 2003764. Published online 2021 Jun 17. doi: 10.1183/13993003.03764-2020

PMCID:: PMC8209485

Abstract Article PDF–1.0M

Select item 80860378.

RIPK3 Activates MLKL-mediated Necroptosis and Inflammasome Signaling during Streptococcus Infection

Hua-Rong Huang, Soo Jung Cho, Rebecca M. Harris, Jianjun Yang, Santos Bermejo, Lokesh Sharma, Charles S. Dela Cruz, Jin-Fu Xu, Heather W. Stout-Delgado

Am J Respir Cell Mol Biol. 2021 May; 64(5): 579–591. doi: 10.1165/rcmb.2020-0312OC

PMCID:: PMC8086037

Abstract Article PDF–1.8M

Select item 74298749.

RIPK3 collaborates with GSDMD to drive tissue injury in lethal polymicrobial sepsis

Hui Chen, Yinshuang Li, Jianfeng Wu, Guoping Li, Xuan Tao, Kunmei Lai, Ying Yuan, Xiaohong Zhang, Zhenhuan Zou, Yanfang Xu

Cell Death Differ. 2020 Sep; 27(9): 2568–2585. Published online 2020 Mar 9. doi: 10.1038/s41418-020-0524-1

PMCID:: PMC7429874

Abstract Article PDF–7.5M

Select item 731741110.

RIP1 kinase activity is critical for skin inflammation but not for viral propagation

Joshua D. Webster, Youngsu C. Kwon, Summer Park, Hua Zhang, Nick Corr, Nina Ljumanovic, Adeyemi O. Adedeji, Eugene Varfolomeev, Tatiana Goncharov, Jessica Preston, Sara F. Santagostino, Snahel Patel, Min Xu, Jonathan Maher, Brent S. McKenzie, Domagoj Vucic

J Leukoc Biol. 2020 Jun; 107(6): 941–952. Published online 2020 Jan 27. doi: 10.1002/JLB.3MA1219-398R

PMCID:: PMC7317411

Abstract Article PDF–8.4M

Select item 722428311.

Dectin-1-induced RIPK1 and RIPK3 activation protects host against Candida albicans infection

Mengtao Cao, Zhengxi Wu, Qi Lou, Wenli Lu, Jie Zhang, Qi Li, Yifan Zhang, Yikun Yao, Qun Zhao, Ming Li, Haibing Zhang, Youcun Qian

Cell Death Differ. 2019 Dec; 26(12): 2622–2636. Published online 2019 Apr 3. doi: 10.1038/s41418-019-0323-8

PMCID:: PMC7224283

Abstract Article PDF–2.9M

Select item 715375312.

Influenza Virus Z-RNAs Induce ZBP1-Mediated Necroptosis

Ting Zhang, Chaoran Yin, David F. Boyd, Giovanni Quarato, Justin P. Ingram, Maria Shubina, Katherine B. Ragan, Takumi Ishizuka, Jeremy Chase Crawford, Bart Tummers, Diego A. Rodriguez, Jia Xue, Suraj Peri, William J. Kaiser, Carolina B. López, Yan Xu, Jason W. Upton, Paul G. Thomas, Douglas R. Green, Siddharth Balachandran

Cell. Author manuscript; available in PMC 2021 Mar 19.

Published in final edited form as: Cell. 2020 Mar 19; 180(6): 1115–1129.e13. doi: 10.1016/j.cell.2020.02.050

PMCID:: PMC7153753

Abstract Article PDF–3.8M

Select item 710563913.

RIPK3 Promotes JEV Replication in Neurons via Downregulation of IFI44L

Peiyu Bian, Chuantao Ye, Xuyang Zheng, Chuanyu Luo, Jiali Yang, Mengyuan Li, Yuan Wang, Jing Yang, Yun Zhou, Fanglin Zhang, Jianqi Lian, Ying Zhang, Zhansheng Jia, Yingfeng Lei

Front Microbiol. 2020; 11: 368. Published online 2020 Mar 24. doi: 10.3389/fmicb.2020.00368

PMCID:: PMC7105639

Abstract Article PDF–6.4M

Select item 687467514.

Transcription modulation by CDK9 regulates inflammatory genes and RIPK3-MLKL-mediated necroptosis in periodontitis progression

Jiao Li, Jiahong Shi, Yue Pan, Yunhe Zhao, Fuhua Yan, Houxuan Li, Lang Lei

Sci Rep. 2019; 9: 17369. Published online 2019 Nov 22. doi: 10.1038/s41598-019-53910-y

PMCID:: PMC6874675

Abstract Article PDF–6.6M

Select item 654812715.

Necroptosis mediators RIPK3 and MLKL suppress intracellular Listeria replication independently of host cell killing

Kazuhito Sai, Cameron Parsons, John S. House, Sophia Kathariou, Jun Ninomiya-Tsuji

J Cell Biol. 2019 Jun 28; 218(6): 1994–2005. Published online 2019 Apr 11. doi: 10.1083/jcb.201810014

PMCID:: PMC6548127

Abstract Article PDF–2.1M

Select item 647556716.

Close Relationship between cIAP2 and Human ARDS Induced by Severe H7N9 Infection

Chu Qin, Xiao-yan Sai, Xiu-fen Qian, Yan Wu, Li-fei Zou, Hong-mei Wang, Tao Bian, Zheng Yan

Biomed Res Int. 2019; 2019: 2121357. Published online 2019 Apr 7. doi: 10.1155/2019/2121357

PMCID:: PMC6475567

Abstract Article PDF–2.5M

Select item 639353017.

Loss of periodontal ligament fibroblasts by RIPK3-MLKL-mediated necroptosis in the progress of chronic periodontitis

J. Shi, J. Li, W. Su, S. Zhao, H. Li, L. Lei

Sci Rep. 2019; 9: 2902. Published online 2019 Feb 27. doi: 10.1038/s41598-019-39721-1

PMCID:: PMC6393530

Abstract Article PDF–2.1M

Select item 606252218.

Species-independent contribution of ZBP1/DAI/DLM-1-triggered necroptosis in host defense against HSV1

Hongyan Guo, Ryan P. Gilley, Amanda Fisher, Rebecca Lane, Vanessa J. Landsteiner, Katherine B. Ragan, Cole M. Dovey, Jan E. Carette, Jason W. Upton, Edward S. Mocarski, William J. Kaiser

Cell Death Dis. 2018 Aug; 9(8): 816. Published online 2018 Jul 26. doi: 10.1038/s41419-018-0868-3

PMCID:: PMC6062522

Abstract Article PDF–1.5M

Select item 598537619.

Is Receptor-Interacting Protein Kinase 3 a Viable Therapeutic Target for Mycobacterium tuberculosis Infection?

Michael D. Stutz, Samar Ojaimi, Gregor Ebert, Marc Pellegrini

Front Immunol. 2018; 9: 1178. Published online 2018 May 28. doi: 10.3389/fimmu.2018.01178

PMCID:: PMC5985376

Abstract Article PDF–2.5M

Select item 595754620.

Inflammation and outer blood-retina barrier (BRB) compromise following choroidal murine cytomegalovirus (MCMV) infections

Jinxian Xu, Xinglou Liu, Juan Mo, Brendan Marshall, Libby Perry, Zheng Dong, Ming Zhang

Mol Vis. 2018; 24: 379–394. Published online 2018 May 18.

PMCID:: PMC5957546

Abstract Article PDF–1.5M

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