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Select item 42424511.

Lipoxygenase-catalyzed transformation of epoxy fatty acids to hydroxy-endoperoxides: a potential P450 and lipoxygenase interaction

Tarvi Teder, William E. Boeglin, Alan R. Brash

J Lipid Res. 2014 Dec; 55(12): 2587–2596. doi: 10.1194/jlr.M054072

PMCID:: PMC4242451

Abstract Article PDF–959K

Select item 41038482.

Maresin Biosynthesis and Identification of Maresin 2, a New Anti-Inflammatory and Pro-Resolving Mediator from Human Macrophages

Bin Deng, Chin-Wei Wang, Hildur H. Arnardottir, Yongsheng Li, Chien-Yee Cindy Cheng, Jesmond Dalli, Charles N. Serhan

PLoS One. 2014; 9(7): e102362. Published online 2014 Jul 18. doi: 10.1371/journal.pone.0102362

PMCID:: PMC4103848

Abstract Article PDF–911K

Select item 38400043.

Functional characterization of genetic enzyme variations in human lipoxygenases

Thomas Horn, Kumar Reddy Kakularam, Monika Anton, Constanze Richter, Pallu Reddanna, Hartmut Kuhn

Redox Biol. 2013; 1(1): 566–577. Published online 2013 Nov 11. doi: 10.1016/j.redox.2013.11.001

PMCID:: PMC3840004

Abstract Article PDF–4.2M

Select item 36887394.

The novel 13S,14S-epoxy-maresin is converted by human macrophages to maresin 1 (MaR1), inhibits leukotriene A₄ hydrolase (LTA₄H), and shifts macrophage phenotype

Jesmond Dalli, Min Zhu, Nikita A. Vlasenko, Bin Deng, Jesper Z. Haeggström, Nicos A. Petasis, Charles N. Serhan

FASEB J. 2013 Jul; 27(7): 2573–2583. doi: 10.1096/fj.13-227728

PMCID:: PMC3688739

Abstract Article

Select item 36338135.

Systematic analysis of rat 12/15-lipoxygenase enzymes reveals critical role for spinal eLOX3 hepoxilin synthase activity in inflammatory hyperalgesia

Ann M. Gregus, Darren S. Dumlao, Spencer C. Wei, Paul C. Norris, Laura C. Catella, Flore G. Meyerstein, Matthew W. Buczynski, Joanne J. Steinauer, Bethany L. Fitzsimmons, Tony L. Yaksh, Edward A. Dennis

FASEB J. 2013 May; 27(5): 1939–1949. doi: 10.1096/fj.12-217414

PMCID:: PMC3633813

Abstract Article

Select item 34942516.

Investigations of human platelet-type 12-lipoxygenase: role of lipoxygenase products in platelet activation

Kenneth N. Ikei, Jennifer Yeung, Patrick L. Apopa, Jesús Ceja, Joanne Vesci, Theodore R. Holman, Michael Holinstat

J Lipid Res. 2012 Dec; 53(12): 2546–2559. doi: 10.1194/jlr.M026385

PMCID:: PMC3494251

Abstract Article PDF–1.6M

Select item 33149537.

Up-regulation of 12(S)-lipoxygenase induces a migratory phenotype in colorectal cancer cells

T. Klampfl, E. Bogner, W. Bednar, L. Mager, D. Massudom, I. Kalny, C. Heinzle, W. Berger, S. Stättner, J. Karner, M. Klimpfinger, G. Fürstenberger, P. Krieg, B. Marian

Exp Cell Res. 2012 Apr 1; 318(6): 768–778. doi: 10.1016/j.yexcr.2011.12.017

PMCID:: PMC3314953

Abstract Article

Select item 31780598.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 30232049.

Evidence for activation of inflammatory lipoxygenase pathways in visceral adipose tissue of obese Zucker rats

Swarup K. Chakrabarti, Yeshao Wen, Anca D. Dobrian, Banumathi K. Cole, Qian Ma, Hong Pei, Michael D. Williams, Melissa H. Bevard, George E. Vandenhoff, Susanna R. Keller, Jiali Gu, Jerry L. Nadler

Am J Physiol Endocrinol Metab. 2011 Jan; 300(1): E175–E187. Published online 2010 Oct 26. doi: 10.1152/ajpendo.00203.2010

PMCID:: PMC3023204

Abstract Article

Select item 294522310.

Peroxynitrite-Induced Neuronal Apoptosis Is Mediated by Intracellular Zinc Release and 12-Lipoxygenase Activation

Yumin Zhang, Hong Wang, Jianrong Li, Daniel A. Jimenez, Edwin S. Levitan, Elias Aizenman, Paul A. Rosenberg

J Neurosci. 2004 Nov 24; 24(47): 10616–10627. doi: 10.1523/JNEUROSCI.2469-04.2004

PMCID:: PMC2945223

Abstract Article PDF–420K

Select item 291196011.

Vitamin K Prevents Oxidative Cell Death by Inhibiting Activation of 12-Lipoxygenase in Developing Oligodendrocytes

Jianrong Li, Hong Wang, Paul A. Rosenberg

J Neurosci Res. Author manuscript; available in PMC 2010 Jul 29.

Published in final edited form as: J Neurosci Res. 2009 Jul; 87(9): 1997–2005. doi: 10.1002/jnr.22029

PMCID:: PMC2911960

Abstract Article PDF–1.6M

Select item 277449812.

Oxidative Metabolism of Lipoamino Acids and Vanilloids by Lipoxygenases and Cyclooxygenases

Jeffery J. Prusakiewicz, Melissa V. Turman, Andrew Vila, Heather L. Ball, Ahmad H. Al-Mestarihi, Vincenzo Di Marzo, Lawrence J. Marnett

Arch Biochem Biophys. Author manuscript; available in PMC 2009 Nov 8.

Published in final edited form as: Arch Biochem Biophys. 2007 Aug 15; 464(2): 260–268. Published online 2007 Apr 20. doi: 10.1016/j.abb.2007.04.007

PMCID:: PMC2774498

Abstract Article PDF–1.0M

Select item 276007413.

Oxidative Metabolism of a Fatty Acid Amide Hydrolase-Regulated Lipid, Arachidonoyltaurine

Melissa V. Turman, Philip J. Kingsley, Carol A. Rouzer, Benjamin F. Cravatt, Lawrence J. Marnett

Biochemistry. Author manuscript; available in PMC 2009 Oct 11.

Published in final edited form as: Biochemistry. 2008 Mar 25; 47(12): 3917–3925. Published online 2008 Mar 1. doi: 10.1021/bi702530z

PMCID:: PMC2760074

Abstract Article PDF–764K

Select item 267294914.

Role of Src Tyrosine Kinase in the Atherogenic Effects of the 12/15-Lipoxygenase Pathway in Vascular Smooth Muscle Cells

Marpadga A. Reddy, Saurabh Sahar, Louisa M. Villeneuve, Linda Lanting, Rama Natarajan

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2010 Mar 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2009 Mar; 29(3): 387–393. Published online 2008 Dec 18. doi: 10.1161/ATVBAHA.108.179150

PMCID:: PMC2672949

Abstract Article PDF–934K

Select item 263705015.

Large-Scale Proteomics and Phosphoproteomics of Urinary Exosomes

Patricia A. Gonzales, Trairak Pisitkun, Jason D. Hoffert, Dmitry Tchapyjnikov, Robert A. Star, Robert Kleta, Nam Sun Wang, Mark A. Knepper

J Am Soc Nephrol. 2009 Feb; 20(2): 363–379. doi: 10.1681/ASN.2008040406

PMCID:: PMC2637050

Abstract Article

Select item 258550316.

Association of Arachidonate 12 Lipoxygenase Genotype Variation and Glycemic Control With Albuminuria in Type 2 Diabetes

Yongmei Liu, Barry I. Freedman, Kathryn P. Burdon, Carl D. Langefeld, Timothy Howard, David Herrington, David C. Goff, Jr., Donald W. Bowden, Lynne E. Wagenknecht, Catherine C. Hedrick, Stephen S. Rich

Am J Kidney Dis. Author manuscript; available in PMC 2009 Aug 1.

Published in final edited form as: Am J Kidney Dis. 2008 Aug; 52(2): 242–250. Published online 2008 Mar 25. doi: 10.1053/j.ajkd.2007.12.033

PMCID:: PMC2585503

Abstract Article PDF–494K

Select item 258481517.

12-Lipoxygenase-knockout mice are resistant to inflammatory effects of obesity induced by western diet

Craig S. Nunemaker, Meng Chen, Hong Pei, Sarah D. Kimble, Susanna R. Keller, Jeffrey D. Carter, Zandong Yang, Kellie M. Smith, Runpei Wu, Melissa H. Bevard, James C. Garmey, Jerry L. Nadler

Am J Physiol Endocrinol Metab. 2008 Nov; 295(5): E1065–E1075. Published online 2008 Sep 9. doi: 10.1152/ajpendo.90371.2008