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Select item 101819101.

miR-135a Regulates Atrial Fibrillation by Targeting Smad3

Xueting Fan, Kai Feng, Yonghui Liu, Leixi Yang, Yizhuo Zhao, Liping Tian, Yiqun Tang, Xiaozhi Wang

Cardiovasc Ther. 2023; 2023: 8811996. Published online 2023 May 5. doi: 10.1155/2023/8811996

PMCID:: PMC10181910

Abstract Article PDF–2.1M

Select item 88059282.

Hyperoxia induces alveolar epithelial cell apoptosis by regulating mitochondrial function through small mothers against decapentaplegic 3 (SMAD3) and extracellular signal-regulated kinase 1/2 (ERK1/2)

Jun Jiang, Juan Wang, Cen Li, Lianqin Mo, Dong Huang

Bioengineered. 2022; 13(1): 242–252. Published online 2021 Dec 25. doi: 10.1080/21655979.2021.2012953

PMCID:: PMC8805928

Abstract Article PDF–2.3M

Select item 87409073.

Severe Acute Respiratory Syndrome-associated Coronavirus Nucleocapsid Protein Interacts with Smad3 and Modulates Transforming Growth Factor-β Signaling

Xingang Zhao, John M. Nicholls, Ye-Guang Chen

J Biol Chem. 2008 Feb 8; 283(6): 3272–3280. Published online 2021 Jan 4. doi: 10.1074/jbc.M708033200

PMCID:: PMC8740907

Abstract Article PDF–612K

Select item 86878544.

Zishen Qingre Tongluo Formula Improves Renal Fatty Acid Oxidation and Alleviated Fibrosis via the Regulation of the TGF-β1/Smad3 Signaling Pathway in Hyperuricemic Nephrology Rats

Peng Liu, Chen Wang, Yun Wang, Honghong Zhang, Baoli Liu, Xinping Qiu

Biomed Res Int. 2021; 2021: 2793823. Published online 2021 Dec 13. doi: 10.1155/2021/2793823

PMCID:: PMC8687854

Abstract Article PDF–1.3M

Select item 86184895.

In Vivo Investigation of the Ameliorating Effect of Tempol against MIA-Induced Knee Osteoarthritis in Rats: Involvement of TGF-β1/SMAD3/NOX4 Cue

Hagar B. Abo-zalam, Rania M. Abdelsalam, Rehab F. Abdel-Rahman, Mohamed F. Abd-Ellah, Mahmoud M. Khattab

Molecules. 2021 Nov; 26(22): 6993. Published online 2021 Nov 19. doi: 10.3390/molecules26226993

PMCID:: PMC8618489

Abstract Article PDF–6.4M

Select item 78349686.

Astragaloside IV alleviates silica-induced pulmonary fibrosis via inactivation of the TGF-β1/Smad2/3 signaling pathway

Nannan Li, Ke Wu, Feifei Feng, Lin Wang, Xiang Zhou, Wei Wang

Int J Mol Med. 2021 Mar; 47(3): 16. Published online 2021 Jan 8. doi: 10.3892/ijmm.2021.4849

PMCID:: PMC7834968

Abstract Article PDF–1.0M

Select item 70526537.

Protein arginine methyltransferase 1 mediates renal fibroblast activation and fibrogenesis through activation of Smad3 signaling

Yu Zhu, Chao Yu, Shougang Zhuang

Am J Physiol Renal Physiol. 2020 Feb 1; 318(2): F375–F387. Published online 2019 Dec 9. doi: 10.1152/ajprenal.00487.2019

PMCID:: PMC7052653

Abstract Article

Select item 68244668.

Structural basis for distinct roles of SMAD2 and SMAD3 in FOXH1 pioneer-directed TGF-β signaling

Eric Aragón, Qiong Wang, Yilong Zou, Sophie M. Morgani, Lidia Ruiz, Zuzanna Kaczmarska, Jie Su, Carles Torner, Lin Tian, Jing Hu, Weiping Shu, Saloni Agrawal, Tiago Gomes, José A. Márquez, Anna-Katerina Hadjantonakis, Maria J. Macias, Joan Massagué

Genes Dev. 2019 Nov 1; 33(21-22): 1506–1524. doi: 10.1101/gad.330837.119

PMCID:: PMC6824466

Abstract Article PDF–12M

Select item 63093669.

PPM1A Functions as a Smad Phosphatase to Terminate TGFβ Signaling

Xia Lin, Xueyan Duan, Yao-Yun Liang, Ying Su, Katharine H. Wrighton, Jianyin Long, Min Hu, Candi M. Davis, Jinrong Wang, F. Charles Brunicardi, Yigong Shi, Ye-Guang Chen, Anming Meng, Xin-Hua Feng

Cell. Author manuscript; available in PMC 2018 Dec 28.

Published in final edited form as: Cell. 2006 Jun 2; 125(5): 915–928. doi: 10.1016/j.cell.2006.03.044

PMCID:: PMC6309366

Abstract Article PDF–3.3M

Select item 619768810.

Bone marrow derived-mesenchymal stem cells downregulate IL17A dependent IL6/STAT3 signaling pathway in CCl₄-induced rat liver fibrosis

Shimaa Farouk, Salwa Sabet, Fatma A. Abu Zahra, Akmal A. El-Ghor

PLoS One. 2018; 13(10): e0206130. Published online 2018 Oct 22. doi: 10.1371/journal.pone.0206130

PMCID:: PMC6197688

Abstract Article PDF–2.5M

Select item 598521211.

Neuronal Transforming Growth Factor beta Signaling via SMAD3 Contributes to Pain in Animal Models of Chronic Pancreatitis

Liansheng Liu, Yaohui Zhu, Michaël Noë, Qian Li, Pankaj Jay Pasricha

Gastroenterology. Author manuscript; available in PMC 2019 Jun 1.

Published in final edited form as: Gastroenterology. 2018 Jun; 154(8): 2252–2265.e2. Published online 2018 Mar 2. doi: 10.1053/j.gastro.2018.02.030

PMCID:: PMC5985212

Abstract Article PDF–1.0M

Select item 557259412.

Ginsenoside Rg1 Attenuates Cigarette Smoke-Induced Pulmonary Epithelial-Mesenchymal Transition via Inhibition of the TGF-β1/Smad Pathway

Sibin Guan, Weiguo Xu, Fengfeng Han, Wen Gu, Lin Song, Wenjing Ye, Qian Liu, Xuejun Guo

Biomed Res Int. 2017; 2017: 7171404. Published online 2017 Aug 13. doi: 10.1155/2017/7171404

PMCID:: PMC5572594

Abstract Article PDF–3.0M

Select item 557156113.

Crosstalk between Smad2/3 and specific isoforms of ERK in TGF‐β1‐induced TIMP‐3 expression in rat chondrocytes

Yanhui Zhu, Jianhua Gu, Tong Zhu, Chen Jin, Xiaopeng Hu, Xiang Wang

J Cell Mol Med. 2017 Sep; 21(9): 1781–1790. Published online 2017 Feb 23. doi: 10.1111/jcmm.13099

PMCID:: PMC5571561

Abstract Article PDF–799K

Select item 556199214.

miR-203 inhibits the expression of collagen-related genes and the proliferation of hepatic stellate cells through a SMAD3-dependent mechanism

Danping Hu, Yibing Hu, Wangwang Xu, Huanhuan Yu, Naibin Yang, Shunlan Ni, Rongquan Fu

Mol Med Rep. 2017 Aug; 16(2): 1248–1254. Published online 2017 Jun 6. doi: 10.3892/mmr.2017.6702

PMCID:: PMC5561992

Abstract Article PDF–1.1M

Select item 544379715.

ANO1 inhibits cardiac fibrosis after myocardial infraction via TGF-β/smad3 pathway

Yao Gao, Yan Mei Zhang, Li Jun Qian, Ming Chu, Jian Hong, Di Xu

Sci Rep. 2017; 7: 2355. Published online 2017 May 24. doi: 10.1038/s41598-017-02585-4

PMCID:: PMC5443797

Abstract Article PDF–2.0M

Select item 526843916.

Fluoride Regulate Osteoblastic Transforming Growth Factor-β1 Signaling by Mediating Recycling of the Type I Receptor ALK5

Chen Yang, Yan Wang, Hui Xu

PLoS One. 2017; 12(1): e0170674. Published online 2017 Jan 26. doi: 10.1371/journal.pone.0170674

Correction in:: PLoS One. 2017; 12(4): e0176772.

PMCID:: PMC5268439

Abstract Article PDF–2.0M

Select item 523732017.

Negative immune factors might predominate local tumor immune status and promote carcinogenesis in cervical carcinoma

Minyi Zhao, Yang Li, Xing Wei, Qian Zhang, Hongran Jia, Shimin Quan, Di Cao, Li Wang, Ting Yang, Juan Zhao, Meili Pei, Sijuan Tian, Yang Yu, Yanping Guo, Xiaofeng Yang

Virol J. 2017; 14: 5. Published online 2017 Jan 13. doi: 10.1186/s12985-016-0670-8

PMCID:: PMC5237320

Abstract Article PDF–626K

Select item 511366818.

Local CXCR4 Upregulation in the Injured Arterial Wall Contributes to Intimal Hyperplasia

Xudong Shi, Lian‐Wang Guo, Stephen Seedial, Toshio Takayama, Bowen Wang, Mengxue Zhang, Sarah R. Franco, Yi Si, Mirnal A Chaudhary, Bo Liu, K. Craig Kent

Stem Cells. 2016 Nov; 34(11): 2744–2757. Published online 2016 Jul 17. doi: 10.1002/stem.2442